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Nature (London), ISSN 1476-4687, 04/2011, Volume 472, Issue 7343, pp. 361 - 365
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Capsid - chemistry | Receptors, Pattern Recognition - immunology | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Transcription Factor AP-1 - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | HIV-1 - chemistry | HEK293 Cells | Carrier Proteins - immunology | Cell Line | Retroviridae - chemistry | Ubiquitin-Protein Ligases - metabolism | Retroviridae - immunology | MAP Kinase Kinase Kinases - metabolism | Transcription Factors - metabolism | Capsid - immunology | Carrier Proteins - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Carrier Proteins - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Signal transduction | Efficiency | RNA polymerase | Pattern recognition | Kinases | Evacuations & rescues | Immune system | Index Medicus | HIV-1/immunology | Capsid/immunology | Life Sciences | MAP Kinase Kinase Kinases/metabolism | Carrier Proteins/immunology | Immunology | Transcription Factors/metabolism | Capsid/chemistry | HIV-1/chemistry | Ubiquitin/metabolism | Receptors, Pattern Recognition/immunology | Retroviridae/chemistry | Ubiquitin-Protein Ligases/immunology | Ubiquitin-Conjugating Enzymes/metabolism | HumansImmunity, Innate/immunology | Lipopolysaccharides/pharmacology | Signal Transduction/drug effects | Retroviridae/immunology | Transcription Factor AP-1/metabolism | Lipopolysaccharides/immunology | Ubiquitin-Protein Ligases/metabolism | Carrier Proteins/genetics | Signal Transduction/immunology | NF-kappa B/metabolism | Ubiquitin-Protein Ligases/genetics | Carrier Proteins/metabolism | Receptors, Pattern Recognition/metabolism
Journal Article
Cell (Cambridge), ISSN 0092-8674, 10/2018, Volume 175, Issue 2, pp. 488 - 501.e22
.... However, synthesis of HIV DNA during infection is not sufficient for immune activation. The capsid protein, which associates with viral DNA, has a pivotal role in enabling cGAS-mediated immune activation... 
HIV-1 | macrophages | HIV-2 | dendritic cells | innate immunity | NONO | capsid | cGAS | STING | innate immune sensors | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dendritic Cells - immunology | Humans | Octamer Transcription Factors - immunology | Nucleotidyltransferases - physiology | HIV Infections - immunology | Signal Transduction - immunology | Capsid Proteins - physiology | Cell Nucleus - metabolism | Octamer Transcription Factors - physiology | Nuclear Matrix-Associated Proteins - physiology | Capsid Proteins - immunology | HIV-2 - genetics | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Capsid - metabolism | Macrophages - immunology | RNA-Binding Proteins - physiology | Capsid Proteins - metabolism | Nuclear Matrix-Associated Proteins - immunology | RNA-Binding Proteins - immunology | Nuclear Matrix-Associated Proteins - metabolism | HIV-1 - genetics | Host-Pathogen Interactions | DNA, Viral - immunology | Immunity, Innate - immunology | HIV-1 - immunology | HIV-2 - immunology | DNA, Viral - genetics | RNA-Binding Proteins - metabolism | Antiviral agents | Viral proteins | Dendritic cells | HIV testing | Sensors | HIV (Viruses) | Macrophages | Health aspects | Cyclic guanylic acid | Protein binding | Life Sciences | Genetics | Human genetics
Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e61101 - e61101
.... The most frequent human B cell response is directed to the internal protein VP6 on the surface of double-layered particles, which is normally exposed only in the intracellular environment... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antibodies, Viral - metabolism | Antigens, Viral - metabolism | Epitopes - metabolism | Virus Replication - genetics | Humans | Rotavirus - physiology | Rotavirus - immunology | Molecular Sequence Data | Virion - genetics | Antigens, Viral - genetics | Neutralization Tests | Host-Pathogen Interactions - immunology | Epitopes - immunology | Rotavirus - metabolism | HEK293 Cells | B-Lymphocytes - virology | Capsid Proteins - immunology | Transcription, Genetic | Rotavirus Infections - virology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Caco-2 Cells | Protein Structure, Tertiary | Virion - immunology | Amino Acid Sequence | Cell Line | Immunoglobulin A - metabolism | Capsid Proteins - metabolism | Models, Molecular | Virus Replication - immunology | Protein Binding - immunology | Virion - metabolism | Rotavirus Infections - immunology | Sequence Homology, Amino Acid | Antigens, Viral - immunology | Animals | B-Lymphocytes - immunology | Immunoglobulin A - immunology | Antibodies, Viral - immunology | Epitopes - chemistry | Antibodies, Monoclonal - metabolism | Capsid Proteins - genetics | Genetic aspects | Genetic transcription | B cells | Vaccines | Immunoglobulin A | Pediatrics | Transcription | Mucosa | Antibodies | Viruses | Infections | Biochemistry | Immunity | Crystallography | Proteins | Immunology | Physiology | Immunoglobulins | Automation | Particulates | Biophysics | Medicine | Pathology | Lymphocytes B | Quaternary structure | Scientific imaging | Intracellular | Human behavior | Mass spectrometry | Protein structure | Immunoassays | Neutralization | Index Medicus | Quaternary
Journal Article
Virus research, ISSN 0168-1702, 03/2017, Volume 231, pp. 166 - 175
....•Vaccinations with minor capsid protein L2 induce cross-neutralizing but low-titer antibodies against mucosal and skin HPV... 
HPV infection and disease | Human papillomavirus (HPV) vaccine | Squamous cell cancer (SCC) | Cutaneous and anogenital warts (condylomata) | Minor capsid protein (L2) | Cervical cancer (CxCa) | Life Sciences & Biomedicine | Science & Technology | Virology | Immunogenicity, Vaccine | Recombinant Fusion Proteins - immunology | Head and Neck Neoplasms - virology | Oncogene Proteins, Viral - chemistry | Papillomaviridae - drug effects | Humans | Vaccination | Cross Protection | Papillomavirus Vaccines - biosynthesis | Uterine Cervical Neoplasms - pathology | Epitopes - immunology | Papillomavirus Infections - pathology | Papillomaviridae - immunology | Capsid Proteins - chemistry | Vaccines, Virus-Like Particle | Capsid Proteins - immunology | Papillomavirus Infections - immunology | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Papillomavirus Vaccines - administration & dosage | Antibodies, Viral - biosynthesis | Head and Neck Neoplasms - prevention & control | Papillomaviridae - growth & development | Cancer Vaccines - administration & dosage | Cancer Vaccines - biosynthesis | Uterine Cervical Neoplasms - prevention & control | Uterine Cervical Neoplasms - immunology | Vaccines, Subunit - immunology | Recombinant Fusion Proteins - chemistry | Head and Neck Neoplasms - pathology | Papillomaviridae - pathogenicity | Cancer Vaccines - immunology | Head and Neck Neoplasms - immunology | Animals | Vaccines, Subunit - biosynthesis | Antibodies, Neutralizing - biosynthesis | Papillomavirus Infections - prevention & control | Vaccines, Subunit - administration & dosage | Immunity, Humoral - drug effects | Recombinant Fusion Proteins - genetics | Uterine Cervical Neoplasms - virology | Papillomavirus Vaccines - immunology | Epitopes - chemistry | Mice | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Prevention | Vaccines | Viral proteins | Health aspects | Papillomavirus infections | Wildlife conservation | Peptides | Development and progression | Papillomaviruses | Warts | Sexually transmitted diseases | Analysis | Skin | Cervical cancer | Antigenic determinants | Index Medicus | Human Papillomavirus (HPV) Vaccine | Cervical Cancer (CxCa) | Minor Capsid Protein (L2) | Squamous Cell Cancer (SCC) | cutaneous and anogenital warts (condylomata)
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 06/2009, Volume 324, Issue 5933, pp. 1444 - 1447
Rotavirus outer-layer protein VP7 is a principal target of protective antibodies... 
Infectious diseases | Rotavirus | Neutralizing antibodies | Virions | Vaccination | Disulfides | Antibodies | Reports | Trimers | Epitopes | Virology | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Subunits | Antibodies, Viral - metabolism | Antigens, Viral - metabolism | Calcium - metabolism | Protein Multimerization | Rotavirus - immunology | Molecular Sequence Data | Antigens, Viral - genetics | Crystallography, X-Ray | Neutralization Tests | Rotavirus - chemistry | Epitopes - immunology | Immunoglobulin Fab Fragments - metabolism | Capsid Proteins - chemistry | Capsid Proteins - immunology | Binding Sites | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Serotyping | Protein Structure, Tertiary | Amino Acid Sequence | Capsid Proteins - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Antigens, Viral - chemistry | Protein Folding | Antigens, Viral - immunology | Immunoglobulin Fab Fragments - chemistry | Antibodies, Viral - chemistry | Antibodies, Viral - immunology | Antibodies, Monoclonal - metabolism | Immunoglobulin Fab Fragments - immunology | Mutation | Binding Sites, Antibody | Capsid Proteins - genetics | Proteins | Viral proteins | Rotaviruses | Physiological aspects | Research | Chemical properties | Structure | Protein binding | Viruses | Immunology | Crystal structure | Index Medicus
Journal Article
Journal of virology, ISSN 1098-5514, 09/2012, Volume 86, Issue 18, pp. 9899 - 9910
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13114 - 13119
.... We previously showed that murine coronavirus (MHV) accessory protein ns2, a 2H phosphoesterase superfamily member, is a phosphodiesterase (PDE... 
Coronavirus | Rotavirus | RNA | Liver | Antivirals | Viruses | Amino acids | Mice | Infections | Murine hepatitis virus | Interferon-stiumulated gene | RNA capping enzyme | Nidovirales | Reoviridae | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Endoribonucleases - genetics | Humans | Rotavirus - physiology | Rotavirus - immunology | Molecular Sequence Data | RNA Viruses - physiology | Immunoblotting | Murine hepatitis virus - physiology | Host-Pathogen Interactions - immunology | Murine hepatitis virus - immunology | Rotavirus - metabolism | Macrophages - virology | Oligoribonucleotides - metabolism | RNA Viruses - immunology | Binding Sites - immunology | Capsid Proteins - immunology | RNA Virus Infections - immunology | Macrophages - immunology | Viral Nonstructural Proteins - immunology | 2',5'-Oligoadenylate Synthetase - metabolism | Amino Acid Sequence | Cell Line | Phosphoric Diester Hydrolases - metabolism | Endoribonucleases - metabolism | Capsid Proteins - metabolism | Murine hepatitis virus - metabolism | Cells, Cultured | Viral Nonstructural Proteins - genetics | Phosphoric Diester Hydrolases - genetics | RNA Virus Infections - virology | RNA Viruses - metabolism | Binding Sites - genetics | Mice, Knockout | Phosphoric Diester Hydrolases - immunology | Sequence Homology, Amino Acid | Immunity, Innate - immunology | Macrophages - metabolism | Animals | 2',5'-Oligoadenylate Synthetase - immunology | Adenine Nucleotides - metabolism | Viral Nonstructural Proteins - metabolism | Mutation | Capsid Proteins - genetics | Endoribonucleases - immunology | RNA viruses | Antiviral agents | Immune response | Physiological aspects | Dosage and administration | Research | Phosphodiesterases | Health aspects | Index Medicus | interferon-stiumulated gene | Biological Sciences
Journal Article