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PLoS Pathogens, ISSN 1553-7366, 10/2009, Volume 5, Issue 10, pp. e1000632 - e1000632
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2015, Volume 10, Issue 1, p. e116389
Clinical studies suggest that responses to HPV16 E6E7L2 fusion protein (TA-CIN) vaccination alone are modest, and GPI-0100 is a well-tolerated, potent... 
PHASE-II TRIAL | MULTIDISCIPLINARY SCIENCES | HUMAN-PAPILLOMAVIRUS VACCINES | VIRUS-LIKE PARTICLE | VULVAL INTRAEPITHELIAL NEOPLASIA | TA-CIN | CERVICAL-CANCER | MUCOSAL VACCINATION | ANTITUMOR IMMUNITY | HEALTHY-VOLUNTEERS | DNA VACCINATION | Recombinant Fusion Proteins - immunology | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Papillomavirus Vaccines - genetics | Recombinant Fusion Proteins - pharmacology | Saponins - administration & dosage | Humans | Papillomavirus E7 Proteins - immunology | Papillomavirus E7 Proteins - genetics | Papillomavirus Infections - therapy | Neoplasms - virology | Antibodies, Neutralizing - immunology | Neoplasms - therapy | Vaccination - methods | HEK293 Cells | Capsid Proteins - immunology | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Antineoplastic Agents - pharmacology | Papillomavirus Vaccines - administration & dosage | Recombinant Fusion Proteins - administration & dosage | Mice, Inbred C57BL | Repressor Proteins - genetics | Treatment Outcome | Combined Modality Therapy | Cisplatin - pharmacology | Papillomavirus Vaccines - pharmacology | Animals | Repressor Proteins - immunology | Cell Line, Tumor | Antibodies, Viral - immunology | Mice, Inbred BALB C | Oncogene Proteins, Viral - immunology | CD8-Positive T-Lymphocytes - immunology | Capsid Proteins - genetics | Saponins - pharmacology | Drug therapy | Health aspects | Papillomavirus infections | Cisplatin | Adjuvant treatment | Cancer | Animal models | CD8 antigen | Vaccination | Lymphocytes T | CD4 antigen | Chemotherapy | Immunogenicity | Lungs | Neutralizing | Remission | Mice | Fusion protein | Tumors
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 2014, Volume 20, Issue 9, pp. 519 - 528
Highlights • Apoptins are viral proteins that trigger cell death. • Apoptins show cancer-selective toxicity. • Potential delivery methods are being assayed for... 
Pathology | anaphase-promoting complex | protein phosphatase 2A | protein kinase C | CDK2 | anticancer agents | Protein kinase C | Anticancer agents | Anaphase-promoting complex | Protein phosphatase 2A | NEWCASTLE-DISEASE-VIRUS | MEDICINE, RESEARCH & EXPERIMENTAL | CHICKEN ANEMIA VIRUS | ATTENUATED SALMONELLA-TYPHIMURIUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ONCOLYTIC VIRUS | CELL-DEATH | CELL BIOLOGY | NUCLEAR-LOCALIZATION | IN-VITRO | HEPATOCELLULAR-CARCINOMA | HUMAN GYROVIRUS | ADENOVIRUS EXPRESSING APOPTIN | Apoptosis - drug effects | Humans | Chicken anemia virus - chemistry | Antineoplastic Agents - administration & dosage | Gyrovirus - chemistry | Animals | Capsid Proteins - physiology | Viral Proteins - isolation & purification | Viral Proteins - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Drug Delivery Systems - methods | Capsid Proteins - pharmacology | Proteins | Antimitotic agents | Medical colleges | Care and treatment | Antineoplastic agents | Cells | Cancer | Basic Medicine | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cell and Molecular Biology | Cancer and Oncology | Klinisk medicin | Cell- och molekylärbiologi | anticancer agents; anaphase-promoting complex; CDK2; protein kinase C; protein phosphatase 2A | Cancer och onkologi
Journal Article
Virology, ISSN 0042-6822, 2015, Volume 485, pp. 128 - 134
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2013, Volume 9, Issue 5, p. e1003334
Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of... 
VACCINATION PROGRAMS | NEUTRALIZING ACTIVITY | FED COLOSTRUM SUPPLEMENTS | MICROBIOLOGY | CONFER PROTECTION | VIROLOGY | BOVINE ROTAVIRUS | IMMUNE-RESPONSES | NASAL IMMUNIZATION | VIRUS-LIKE PARTICLES | MATERNAL ANTIBODIES | MONOCLONAL-ANTIBODIES | PARASITOLOGY | Antibodies, Viral - pharmacology | Humans | Rotavirus - immunology | Rotavirus - genetics | Antigens, Viral - genetics | Rotavirus Infections - genetics | Antibodies, Neutralizing - immunology | Swine | Diarrhea - immunology | Capsid Proteins - immunology | Rotavirus Infections - virology | Antibodies, Monoclonal - immunology | Antibodies, Monoclonal - pharmacology | Diarrhea - virology | Antibodies, Neutralizing - pharmacology | Antibodies, Neutralizing - genetics | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Rotavirus Infections - immunology | Antibodies, Monoclonal - genetics | Antigens, Viral - immunology | Camelids, New World | Animals | Rotavirus Infections - drug therapy | Capsid Proteins - antagonists & inhibitors | Recombinant Proteins - immunology | Diarrhea - genetics | Antibodies, Viral - immunology | Diarrhea - drug therapy | Antibodies, Viral - genetics | Capsid Proteins - genetics | Viral antibodies | Care and treatment | Immune response | Rotaviruses | Antibodies | Diarrhea | Research | Properties | Testing | Nutrition research | Statistical analysis | Cloning | Mortality | Colleges & universities | Viruses | Vaccines | Milk
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23317
Background: The application of viral elements in tumor therapy is one facet of cancer research. Recombinant capsid protein VP1 (rVP1) of foot-and-mouth disease... 
BREAST-CANCER | TARGETED THERAPIES | BCL-XL | SERUM-LEVELS | BIOLOGY | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | DOWN-REGULATION | MOUTH-DISEASE VIRUS | ADENOVIRUS E4ORF4 PROTEIN | CANCER PROGRESSION | NF-KAPPA-B | Immunohistochemistry | Immunoprecipitation | Apoptosis - drug effects | Recombinant Proteins - pharmacology | Blotting, Western | Animals | Flow Cytometry | Liver Neoplasms - metabolism | Cell Line, Tumor | Chemokine CCL2 - biosynthesis | Chemokine CCL2 - metabolism | Mice | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Capsid Proteins - pharmacology | Carcinoma, Hepatocellular - metabolism | Viral proteins | Analysis | Development and progression | Foot-and-mouth disease | Research | Metastasis | Hepatoma | Health aspects | Recombinant proteins | Apoptosis | VP1 protein | Transcription factors | Intravenous administration | Capsid protein | Agricultural biotechnology | Foot & mouth disease | AKT protein | Cancer therapies | Anticancer properties | Metastases | Proteins | Liver cancer | Mitochondria | Tumorigenesis | Inhibition | Growth factors | Medical research | NF-κB protein | Cytokines | Chemotherapy | Hepatocytes | Ligands | Gene therapy | Viability | Cell migration | Monocyte chemoattractant protein 1 | Cell proliferation | Biotechnology | Animal models | Phosphorylation | Bax protein | Colorectal cancer | Viruses | Hepatocellular carcinoma | Activation | Kinases | Rodents | Tumor necrosis factor-TNF | Recombinant | Translocation | Deactivation | Data processing | Pharmacology | Breast cancer | Tumor cell lines | Chemical compounds | Medical prognosis | Cell lines | Antitumor activity | Prostate cancer | Chemokines | Cancer
Journal Article
BMC Cancer, ISSN 1471-2407, 10/2013, Volume 13, Issue 1, pp. 488 - 488
Background: Chicken Anemia Virus (CAV) VP3 protein (also known as Apoptin), a basic and proline-rich protein has a unique capability in inducing apoptosis in... 
Microinjection | VP3 | Chang cells | Apoptin | MCF7 cells | Apoptosis | Truncation | LOCALIZATION | CHICKEN ANEMIA VIRUS | ONCOLOGY | KINASE | TUMOR | Recombinant Fusion Proteins - isolation & purification |