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Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 03/2010, Volume 87, Issue 3, pp. 322 - 329
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2016, Volume 60, Issue 1, pp. 105 - 114
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 63, Issue 4, pp. 805 - 812
Background & Aims Paritaprevir, ombitasvir, and dasabuvir are direct-acting antivirals for treatment of chronic hepatitis C virus (HCV) infection. The aim of... 
Gastroenterology and Hepatology | Direct-acting antiviral agents | Ombitasvir | Chronic hepatitis C | Hepatic impairment | Ritonavir | Paritaprevir | Pharmacokinetics | Dasabuvir | ABT-450/R-OMBITASVIR | TRANSPORTER EXPRESSION | RIBAVIRIN | LIVER-DISEASE | GENOTYPE 1 | THERAPY | CIRRHOSIS | HCV | GASTROENTEROLOGY & HEPATOLOGY | Antiviral Agents - pharmacokinetics | Humans | Middle Aged | Cytochrome P-450 CYP3A Inhibitors - pharmacokinetics | Male | Anilides - pharmacokinetics | Carbamates - administration & dosage | Hepatitis C, Chronic - complications | Carbamates - pharmacokinetics | Dose-Response Relationship, Drug | Uracil - administration & dosage | Ribavirin - administration & dosage | Ribavirin - pharmacokinetics | Female | Drug Therapy, Combination | Liver Function Tests | Cytochrome P-450 CYP3A Inhibitors - administration & dosage | Ritonavir - administration & dosage | Macrocyclic Compounds - pharmacokinetics | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Hepatic Insufficiency - blood | Hepatitis C, Chronic - blood | Sulfonamides - pharmacokinetics | Ritonavir - pharmacokinetics | Anilides - administration & dosage | Macrocyclic Compounds - administration & dosage | Hepatic Insufficiency - etiology | Uracil - pharmacokinetics | Sulfonamides - administration & dosage | Uracil - analogs & derivatives | Antiviral agents | Safety and security measures | Hepatitis C virus | Hepatitis C | Index Medicus
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 05/2015, Volume 15, Issue 5, pp. 1313 - 1322
The authors describe the drug–drug interaction profile of the he patitis C direct‐acting antiviral agents ABT‐450, ombitasvir, and dasabuvir with cyclosporine... 
infectious disease | clinical research/practice | pharmacology | calcineurin inhibitor: cyclosporine A (CsA) | pharmacokinetics/pharmacodynamics | immunosuppressant | infection and infectious agents | calcineurin inhibitor: tacrolimus | liver transplantation/hepatology | viral: hepatitis C | SURGERY | ABT-450/R-OMBITASVIR | LIVER-TRANSPLANTATION | EFFICACY | DRUG-INTERACTIONS | TRANSPORTERS | INFECTION | HCV | RIBAVIRIN | INHIBITOR | HEPATITIS-C | TRANSPLANTATION | Antiviral Agents - pharmacokinetics | Hepatitis C - drug therapy | Area Under Curve | Humans | Middle Aged | Male | Anilides - pharmacokinetics | Carbamates - administration & dosage | Healthy Volunteers | Carbamates - pharmacokinetics | Young Adult | Uracil - administration & dosage | Cyclosporine - pharmacokinetics | Adult | Female | Tacrolimus - administration & dosage | Hepacivirus - drug effects | Drug Administration Schedule | Macrocyclic Compounds - pharmacokinetics | Tacrolimus - pharmacokinetics | Antiviral Agents - administration & dosage | Sulfonamides - pharmacokinetics | Anilides - administration & dosage | Adolescent | Cyclosporine - administration & dosage | Macrocyclic Compounds - administration & dosage | Uracil - pharmacokinetics | Sulfonamides - administration & dosage | Uracil - analogs & derivatives | Dosage and administration | Liver diseases | Drug therapy, Combination | Tacrolimus | Hepatitis C virus | Hepatitis C | Hepatitis | Medical research | Drug dosages | Index Medicus | practice | pharmacodynamics | hepatology | clinical research | pharmacokinetics | Original | liver transplantation
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 03/2017, Volume 83, Issue 3, pp. 527 - 539
Journal Article
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 04/2016, Volume 62, Issue 8, pp. 972 - 979
Background. Guidelines for the treatment of human immunodeficiency virus (HIV) infection consistently recommend initiation of antiretroviral therapy in... 
pharmacokinetics | direct-acting antiviral HCV drugs | HIV | hepatitis C | HIV protease inhibitors | INFECTIOUS DISEASES | ABT-450/R-OMBITASVIR | MICROBIOLOGY | RIBAVIRIN | IMMUNOLOGY | THERAPY | HCV | RITONAVIR | Anilides - therapeutic use | Antiviral Agents - pharmacokinetics | Hepatitis C - drug therapy | Coinfection - drug therapy | Humans | Middle Aged | Hepatitis C, Chronic - virology | Male | Anilides - pharmacokinetics | Carbamates - administration & dosage | Hepatitis C, Chronic - complications | Healthy Volunteers | Carbamates - pharmacokinetics | Young Adult | Drug Therapy, Combination - adverse effects | Drug Interactions | Uracil - administration & dosage | HIV Protease Inhibitors - pharmacokinetics | Adult | Female | Hepatitis C - complications | HIV Protease Inhibitors - adverse effects | Hepacivirus - drug effects | Drug Administration Schedule | Ritonavir - administration & dosage | Antiviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | Macrocyclic Compounds - pharmacokinetics | Uracil - therapeutic use | HIV Protease Inhibitors - administration & dosage | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Coinfection - virology | Sulfonamides - pharmacokinetics | Macrocyclic Compounds - therapeutic use | Ritonavir - pharmacokinetics | Anilides - administration & dosage | Sulfonamides - therapeutic use | Adolescent | HIV Infections - complications | Hepatitis C - virology | HIV Infections - drug therapy | Macrocyclic Compounds - administration & dosage | Carbamates - therapeutic use | Uracil - pharmacokinetics | Sulfonamides - administration & dosage | Uracil - analogs & derivatives | Antiviral agents | Care and treatment | Research | Hepatitis C virus | HIV (Viruses) | Patients | Health aspects | Methods | Antiretroviral drugs | Hepatitis | Protease inhibitors | Human immunodeficiency virus--HIV | Medical treatment | Index Medicus
Journal Article
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 06/2014, Volume 54, Issue 6, pp. 649 - 656
Statins are commonly used medications by HIV-1 patients. Elvitegravir/cobicistat/emtricitabine/tenofovir DF is a single tablet regimen for the treatment of... 
pharmacokinetics | organic anion transporting polypeptide | breast cancer resistance protein | Stribild | statins | elvitegravir | HIV PROTEASE INHIBITORS | INTEGRASE | EMTRICITABINE | CO-FORMULATED ELVITEGRAVIR | INITIAL TREATMENT | TRANSPORT | EFAVIRENZ | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | INFECTION | TENOFOVIR | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Anti-HIV Agents - pharmacology | Fluorobenzenes - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Pyrimidines - blood | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Male | Neoplasm Proteins - antagonists & inhibitors | Carbamates - pharmacokinetics | Fluorobenzenes - pharmacology | Drug Interactions | Organic Anion Transporters, Sodium-Independent - metabolism | Quinolones - pharmacokinetics | Madin Darby Canine Kidney Cells | Solute Carrier Organic Anion Transporter Family Member 1B3 | Carbamates - pharmacology | Organic Anion Transporters - antagonists & inhibitors | Rosuvastatin Calcium | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Sulfonamides - pharmacokinetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Pyrimidines - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Cobicistat | ATP-Binding Cassette Transporters - antagonists & inhibitors | Thiazoles - blood | Cricetulus | Quinolones - pharmacology | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Thiazoles - pharmacokinetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Quinolones - blood | Sulfonamides - blood | ATP-Binding Cassette Transporters - metabolism | Adult | Female | Anti-HIV Agents - blood | Drug Therapy, Combination | Fluorobenzenes - blood | CHO Cells | Carbamates - blood | Animals | Anti-HIV Agents - pharmacokinetics | Dogs | Thiazoles - pharmacology | Drug Combinations | Rosuvastatin | Dosage and administration | Pharmacokinetics | Analysis | Confidence intervals | Rodents | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 63, Issue 1, pp. 20 - 29
Journal Article
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 8/2016, Volume 55, Issue 8, pp. 1003 - 1014
Journal Article