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Cancer letters, ISSN 0304-3835, 2013, Volume 332, Issue 2, pp. 295 - 303
Journal Article
Drug metabolism and disposition, ISSN 1521-009X, 2012, Volume 40, Issue 9, pp. 1744 - 1756
Interindividual variability in activity of uptake transporters is evident in vivo, yet limited data exist in vitro, confounding in vitro-in vivo extrapolation.... 
DRUG TRANSPORTERS | IN-VITRO CLEARANCE | CRYOPRESERVED HUMAN HEPATOCYTES | HMG-COA REDUCTASE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTING POLYPEPTIDES | HEPATIC-UPTAKE | HEALTHY-VOLUNTEERS | METABOLIC ENZYMES | RECEPTOR ANTAGONIST | PREDICTION | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Species Specificity | Valsartan | Hypoglycemic Agents - metabolism | Benzoates - metabolism | Humans | Antihypertensive Agents - metabolism | Hepatocytes - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Angiotensin II Type 1 Receptor Blockers - metabolism | Organic Anion Transporters - metabolism | Pyrimidines - metabolism | Quinolines - pharmacology | Tetrazoles - metabolism | Carbamates - metabolism | Dose-Response Relationship, Drug | Fluorobenzenes - pharmacology | Drug Interactions | Hydroxymethylglutaryl-CoA Reductase Inhibitors - metabolism | Biological Transport | Piperidines - pharmacology | Hepatocytes - drug effects | Carbamates - pharmacology | Pravastatin - pharmacology | Fluorobenzenes - metabolism | Piperidines - metabolism | Pravastatin - metabolism | Valine - analogs & derivatives | Rats | Rosuvastatin Calcium | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Hypoglycemic Agents - pharmacology | Quinolines - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Valine - metabolism | Models, Biological | Benzimidazoles - metabolism | Sulfonamides - metabolism | Benzoates - pharmacology | Benzimidazoles - pharmacology | Kinetics | Valine - pharmacology | Organic Anion Transporters - drug effects
Journal Article
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 15, pp. 11810 - 11819
gamma-Secretase-mediated cleavage of amyloid precursor protein (APP) results in the production of Alzheimer disease-related amyloid-beta (A beta) peptides. The... 
TARGET | PROTEIN | PATTERN | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSMEMBRANE DOMAIN | INHIBITORS | BINDING-SITES | EXPRESSION | FAILURE | PRESENILIN-1 | Pyridines - chemistry | Receptors, Notch - metabolism | Humans | Receptor, EphA4 - metabolism | Pyrimidines - chemistry | Brain - metabolism | Alanine - analogs & derivatives | Dibenzazepines - pharmacology | Drug Interactions | Azepines - chemistry | Piperidines - pharmacology | Protein Processing, Post-Translational - drug effects | Pyrans - chemistry | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Female | Pyrans - pharmacology | Alanine - pharmacology | Carbamates - pharmacology | Binding, Competitive | Guinea Pigs | Amyloid beta-Peptides - biosynthesis | Dipeptides - pharmacology | Mice, Inbred C57BL | Rats | Imidazoles - pharmacology | Pyrimidines - pharmacology | Receptor, EphB2 - metabolism | Sulfonamides - pharmacology | Azepines - pharmacology | Brain - drug effects | Sulindac - analogs & derivatives | Amyloid Precursor Protein Secretases - metabolism | Animals | Cell-Free System | Protein Binding | Mice | Pyridines - pharmacology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Flurbiprofen - pharmacology | Sulindac - pharmacology | Neurodegenerative Diseases | Secretases | Neurobiology | Intramembrane Proteolysis | Amyloid | Pharmacology | Alzheimer Disease
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 1740-634X, 2008, Volume 34, Issue 3, pp. 593 - 606
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 05/2018, Volume 43, Issue 6, pp. 1284 - 1296
... and Pharmacology, Sapienza University of Rome, Rome, Italy; 2Department of Science, Section of Biomedical Sciences and Technologies, University Roma Tre, Rome, Italy... 
SYSTEM | 2-ARACHIDONOYLGLYCEROL | ANXIETY | PSYCHIATRY | ANANDAMIDE | POSTTRAUMATIC-STRESS | EXPOSURE THERAPY | NEUROSCIENCES | FEAR EXTINCTION | MEMORY | PHARMACOLOGY & PHARMACY | MODULATION | CANNABINOIDS | Cannabinoid Receptor Modulators - pharmacology | Endocannabinoids - metabolism | Synaptic Transmission - physiology | Stress Disorders, Post-Traumatic - metabolism | Extinction, Psychological - drug effects | Male | Arachidonic Acids - metabolism | Piperidines - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Psychotropic Drugs - pharmacology | Synaptic Transmission - drug effects | Benzamides - pharmacology | Social Isolation | Extinction, Psychological - physiology | Carbamates - pharmacology | Disease Models, Animal | Amidohydrolases - metabolism | Morpholines - pharmacology | Amidohydrolases - antagonists & inhibitors | Glycerides - metabolism | Rats, Sprague-Dawley | Naphthalenes - pharmacology | Animals | Benzoxazines - pharmacology | Electroshock | Benzodioxoles - pharmacology | Drugs | Therapy | Mental disorders | Memory | Posttraumatic stress disorder | Neuromodulation | Modulators | Risk factors | Mimicry | Training | Learning | Receptors | Endocannabinoid system | Social behavior | 2-Arachidonylglycerol | Social interactions | Post-traumatic stress disorder | Rats | Pharmacology | Exposure | Cannabinoid CB1 receptors | Trauma | Anandamide | Hydrolysis | Post traumatic stress disorder | Inhibitors | Social interaction | Social isolation | Neurotransmission | Hippocampus | 2-Arachidonoylglycerol | Social factors | Psychological stress | Risk analysis | Extinction behavior | Original
Journal Article
Journal Article
Nature chemical biology, ISSN 1552-4469, 2014, Volume 10, Issue 8, pp. 656 - 663
Journal Article