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European Journal of Heart Failure, ISSN 1388-9842, 08/2005, Volume 7, Issue 5, pp. 710 - 721
Surveys of prescribing patterns in both hospitals and primary care have usually shown delays in translating the evidence from clinical trials of... 
Heart failure | Isosorbide dinitrate | Beta‐blockers | Digoxin | Angiotensin receptor blockers | Pharmacology | Aldosterone antagonists | Treatment | Eplerenone | Spironolactone | Hydralazine | ACE inhibitors | Clinical recommendations | Beta-blockers | VENTRICULAR SYSTOLIC DYSFUNCTION | heart failure | treatment | CARDIAC & CARDIOVASCULAR SYSTEMS | angiotensin receptor blockers | QUALITY-OF-CARE | hydralazine | eplerenone | isosorbide dinitrate | RANDOMIZED INTERVENTION TRIAL | beta-blockers | MEDICAL-TREATMENT | GENERAL-PRACTICE | digoxin | spironolactone | CONVERTING-ENZYME-INHIBITORS | clinical recommendations | CARDIAC-INSUFFICIENCY | pharmacology | NATIONAL-SURVEY | aldosterone antagonists | ELDERLY-PATIENTS | Benzopyrans - therapeutic use | Valsartan | Angiotensin Receptor Antagonists | Bisoprolol - therapeutic use | Humans | Carbazoles - administration & dosage | Heart Failure - physiopathology | Valine - administration & dosage | Enalapril - therapeutic use | Ethanolamines - administration & dosage | Indoles - administration & dosage | Ramipril - administration & dosage | Captopril - therapeutic use | Propanolamines - therapeutic use | Lisinopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Benzimidazoles - administration & dosage | Tetrazoles - administration & dosage | Ramipril - therapeutic use | Drug Therapy, Combination | Enalapril - administration & dosage | Spironolactone - therapeutic use | Adrenergic beta-Antagonists - administration & dosage | Adrenergic beta-Antagonists - therapeutic use | Benzimidazoles - therapeutic use | Lisinopril - administration & dosage | Nebivolol | Valine - analogs & derivatives | Metoprolol - therapeutic use | Metoprolol - administration & dosage | Evidence-Based Medicine | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Bisoprolol - administration & dosage | Heart Failure - drug therapy | Mineralocorticoid Receptor Antagonists - therapeutic use | Stroke Volume | Benzopyrans - administration & dosage | Captopril - administration & dosage | Guideline Adherence | Ethanolamines - therapeutic use | Indoles - therapeutic use | Metoprolol - analogs & derivatives | Tetrazoles - therapeutic use | Valine - therapeutic use | Carbazoles - therapeutic use | Propanolamines - administration & dosage | Practice Guidelines as Topic | Prescription writing | Corticosteroids | Isosorbide mononitrate | Family medicine | Nitrates | Peptide hormones | Aldosterone | Preventive health services | Cardiac patients | Angiotensin | Antiandrogens | Medicine, Preventive | Steroids | Index Medicus | Kardiologi | converting-enzyme-inhibitors | Cardiac and Cardiovascular Systems | randomized intervention trial | quality-of-care | elderly-patients | cardiac-insufficiency | national-survey | medical-treatment | ventricular systolic dysfunction | general-practice
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2016, Volume 34, Issue 7, pp. 661 - 668
Journal Article
Clinical Pharmacology in Drug Development, ISSN 2160-763X, 11/2015, Volume 4, Issue 6, pp. 407 - 417
LCZ696 is a first-in-class angiotensin receptor neprilysin inhibitor in development for treatments of hypertension and heart failure indications. In 3 separate... 
LCZ696 | pharmacokinetic drug–drug interaction | amlodipine | hydrochlorothiazide | carvedilol | Pharmacokinetic drug-drug interaction | Amlodipine | Hydrochlorothiazide | Carvedilol | STEADY-STATE PHARMACOKINETICS | ANTAGONIST | NATRIURETIC PEPTIDES | pharmacokinetic drug-drug interaction | HEART-FAILURE | EXCRETION | PHARMACOLOGY & PHARMACY | DYSFUNCTION | VALSARTAN | Hydrochlorothiazide - pharmacokinetics | Diuretics - pharmacokinetics | Humans | Middle Aged | Male | Metabolic Clearance Rate | Tetrazoles - blood | Adrenergic beta-Antagonists - pharmacokinetics | Drug Interactions | Tetrazoles - administration & dosage | Adrenergic beta-Antagonists - adverse effects | Amlodipine - administration & dosage | Arizona | Diuretics - blood | Hydrochlorothiazide - adverse effects | Diuretics - administration & dosage | Administration, Oral | Amlodipine - adverse effects | Propanolamines - adverse effects | Antihypertensive Agents - adverse effects | Antihypertensive Agents - blood | Cross-Over Studies | Models, Biological | Calcium Channel Blockers - administration & dosage | Protease Inhibitors - blood | Calcium Channel Blockers - blood | Propanolamines - administration & dosage | Diuretics - adverse effects | Tetrazoles - pharmacokinetics | Angiotensin Receptor Antagonists - adverse effects | Angiotensin Receptor Antagonists - pharmacokinetics | Calcium Channel Blockers - adverse effects | Area Under Curve | Protease Inhibitors - pharmacokinetics | Carbazoles - administration & dosage | Aminobutyrates - adverse effects | Antihypertensive Agents - administration & dosage | Healthy Volunteers | Propanolamines - pharmacokinetics | Amlodipine - pharmacokinetics | Aminobutyrates - pharmacokinetics | Protease Inhibitors - administration & dosage | Protease Inhibitors - adverse effects | Adult | Female | Carbazoles - blood | Aminobutyrates - administration & dosage | Drug Therapy, Combination | Propanolamines - blood | Hydrochlorothiazide - blood | Adrenergic beta-Antagonists - administration & dosage | Adrenergic beta-Antagonists - blood | Carbazoles - adverse effects | Amlodipine - blood | Drug Administration Schedule | Hydrochlorothiazide - administration & dosage | Antihypertensive Agents - pharmacokinetics | Neprilysin - metabolism | Aminobutyrates - blood | Angiotensin Receptor Antagonists - blood | Carbazoles - pharmacokinetics | Neprilysin - antagonists & inhibitors | Tetrazoles - adverse effects | Calcium Channel Blockers - pharmacokinetics | Angiotensin Receptor Antagonists - administration & dosage | Prescription drugs | Beta blockers | Index Medicus
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 12/2015, Volume 60, Issue 12, pp. 3814 - 3816
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2015, Volume 355, Issue 3, pp. 516 - 527
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 5, pp. 679 - 690
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase that is constitutively activated in certain cancers, following gene alterations such as chromosomal... 
ANAPLASTIC LYMPHOMA KINASE | CELL LUNG-CANCER | ONCOLOGY | EML4-ALK FUSION | THERAPEUTIC TARGET | BCR-ABL | NEUROBLASTOMA | ANTITUMOR-ACTIVITY | ACTIVATING MUTATIONS | EXPERIMENTAL-MODELS | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY | Carbazoles - chemistry | Humans | Carbazoles - administration & dosage | Antineoplastic Agents - administration & dosage | Recombinant Fusion Proteins - metabolism | Dose-Response Relationship, Drug | Recombinant Fusion Proteins - antagonists & inhibitors | Protein Kinase Inhibitors - chemistry | Transfection | Neoplasms - genetics | Piperidines - pharmacology | Time Factors | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Piperidines - administration & dosage | Piperidines - chemistry | Administration, Oral | Models, Molecular | Neoplasms - enzymology | Antineoplastic Agents - chemistry | Mice, SCID | Receptor Protein-Tyrosine Kinases - metabolism | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Protein Conformation | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Carbazoles - pharmacology | Neoplasms - pathology | Receptor Protein-Tyrosine Kinases - chemistry | Tyrosine | Aluminum compounds | Lymphomas | Lung cancer, Non-small cell | Index Medicus
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 06/2012, Volume 95, pp. 1 - 9
Journal Article
Journal Article
European Heart Journal, ISSN 0195-668X, 11/2005, Volume 26, Issue 21, pp. 2259 - 2268
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 01/2012, Volume 37, Issue 2, pp. 422 - 433
Memory consolidation is the process by which acquired information is converted to something concrete to be retrieved later. Here we examined a potential role... 
GABA | passive avoidance test | receptor | bicuculline methiodide | mature brain-derived neurotrophic factor | memory consolidation | NEURONAL-ACTIVITY | LONG-TERM-MEMORY | C-FOS | PSYCHIATRY | NEUROTROPHIC FACTOR | BASOLATERAL AMYGDALA | SYNAPTIC PLASTICITY | NEUROSCIENCES | STATE DEPENDENCY | GABA(A) receptor | IN-VIVO | PHARMACOLOGY & PHARMACY | RECOGNITION MEMORY | ONE-TRIAL AVOIDANCE | Memory - drug effects | Humans | Retention (Psychology) - drug effects | Carbazoles - administration & dosage | Male | Indole Alkaloids - administration & dosage | Retention (Psychology) - physiology | CA1 Region, Hippocampal - drug effects | GABA-A Receptor Antagonists - administration & dosage | Brain-Derived Neurotrophic Factor - pharmacology | Brain-Derived Neurotrophic Factor - physiology | Reaction Time - drug effects | CA1 Region, Hippocampal - metabolism | Anisomycin - administration & dosage | Brain-Derived Neurotrophic Factor - metabolism | Bicuculline - analogs & derivatives | Bicuculline - antagonists & inhibitors | GABA-A Receptor Antagonists - pharmacology | Microinjections | Avoidance Learning - physiology | Bicuculline - pharmacology | Recombinant Proteins - pharmacology | Mice, Inbred ICR | Recombinant Proteins - administration & dosage | Antibodies - pharmacology | Antibodies - administration & dosage | Bicuculline - administration & dosage | Brain-Derived Neurotrophic Factor - administration & dosage | Animals | Indole Alkaloids - pharmacology | Receptors, GABA-A - physiology | Anisomycin - pharmacology | Avoidance Learning - drug effects | Mice | Carbazoles - pharmacology | Memory - physiology | Index Medicus
Journal Article
Addiction Biology, ISSN 1355-6215, 09/2014, Volume 19, Issue 5, pp. 758 - 769
Journal Article
Journal Article