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Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 15, pp. 3870 - 3881
Abstract Development of effective non-invasive drug delivery systems is of great importance to the treatment of Alzheimer's diseases and has made great... 
Advanced Basic Science | Dentistry | Lactoferrin | Brain targeting | Intranasal administration | NAP | Nanoparticle | Alzheimer's disease | FUNCTIONALIZED NANOPARTICLES | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | PLA NANOPARTICLES | ENGINEERING, BIOMEDICAL | ALZHEIMERS-DISEASE | CELL-PENETRATING PEPTIDES | HIPPOCAMPAL-NEURONS | NEUROPROTECTIVE PROTEIN ADNP | AMYLOID BETA-PEPTIDE | CENTRAL-NERVOUS-SYSTEM | PLGA NANOPARTICLES | Thiazoles - blood | Nanoparticles - chemistry | Humans | Ibotenic Acid - pharmacology | Brain - enzymology | Molecular Sequence Data | Carbocyanines - metabolism | Male | Polyethylene Glycols - chemistry | Choline O-Acetyltransferase - metabolism | Peptides - administration & dosage | Thiazoles - pharmacokinetics | Drug Delivery Systems | Brain - metabolism | Neuroprotective Agents - pharmacology | Amyloid beta-Peptides - administration & dosage | Neuroprotective Agents - administration & dosage | Amino Acid Sequence | Cell Line | Lactoferrin - metabolism | Tissue Distribution - drug effects | Neuroprotective Agents - chemistry | Peptides - chemistry | Amyloid beta-Peptides - toxicity | Endocytosis - drug effects | Coumarins - pharmacokinetics | Nanoparticles - ultrastructure | Administration, Intranasal | Rats, Sprague-Dawley | Mice, Inbred ICR | Peptides - pharmacology | Brain - drug effects | Coumarins - pharmacology | Polyesters - chemistry | Animals | Coumarins - blood | Brain - pathology | Mice | Thiazoles - pharmacology | Acetylcholinesterase - metabolism | Nanoparticles | Drugs | Drug delivery systems | Clathrin | Peptides | Analysis | Lactoferrins | Amyloid beta-protein | Drugstores | Protein binding | Vehicles | Proteins | Brain | X-ray photoelectron spectroscopy | Hippocampus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 03/2016, Volume 501, Issue 1-2, pp. 271 - 277
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 10/2012, Volume 163, Issue 1, pp. 82 - 92
Gene therapy is a promising therapeutic approach for treating disease, but the efficient delivery of genes to desired locations with minimal side effects... 
Magnetic resonance imaging (MRI) | Gene delivery | Super paramagnetic iron oxide nanoparticles (SPIONs) | Chitosan and PEI coated magnetic micelles (CP–mag-micelles) | Theranostics | Chitosan and PEI coated magnetic micelles (CP-mag-micelles) | STEM-CELLS | CONTRAST AGENTS | DRUG-DELIVERY | CHITOSAN-GRAFT-POLYETHYLENIMINE | POLYMERIC MICELLE | SIRNA DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | CARRIER | IN-VITRO | THERAPY | NANOPARTICLE-BOUND DNA | PHARMACOLOGY & PHARMACY | Fluorescent Dyes - pharmacokinetics | Carbocyanines - pharmacokinetics | Carbocyanines - administration & dosage | Humans | Magnetic Resonance Imaging - methods | Magnetite Nanoparticles - administration & dosage | Polyethylene Glycols - chemistry | Tissue Distribution | Transfection - methods | Magnetic Phenomena | Micelles | Polyesters - administration & dosage | Polyethyleneimine - chemistry | HEK293 Cells | Fluorescent Dyes - administration & dosage | Gene Expression | Mice, Inbred C57BL | Chitosan - administration & dosage | DNA - administration & dosage | Polyethylene Glycols - administration & dosage | Polyesters - chemistry | Magnetite Nanoparticles - chemistry | Animals | Chitosan - chemistry | Polyethyleneimine - administration & dosage | Cell Line, Tumor | Mice | 3T3 Cells | Iron compounds | Magnetic resonance imaging | Ferric oxide | Genes | Nucleic acids | Gene therapy | Polyols | magnetic resonance imaging (MRI) | gene delivery | theranostics | super paramagnetic iron oxide nanoparticles (SPIONs)
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2013, Volume 168, Issue 3, pp. 251 - 261
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 197, pp. 199 - 207
Direct pulmonary delivery of anti-cancer agents is viewed as an effective way of treating lung cancer. Here, we fabricated inhalable nanoparticles made of... 
Nanoparticles | Human serum albumin | Self-assembly | Resistant lung cancer | TRAIL | Inhalation | PROTEIN | DOXORUBICIN | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | MODIFIED EXENDIN-4 | APOPTOSIS-INDUCING LIGAND | THERAPY | PLGA MICROPARTICLES | IN-VIVO | PHARMACOLOGY & PHARMACY | TUMOR-GROWTH | Albumins - chemistry | Lung Neoplasms - drug therapy | Carbocyanines - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Drug Carriers - administration & dosage | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Male | Doxorubicin - chemistry | Antineoplastic Agents - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - pharmacokinetics | Drug Carriers - chemistry | Antineoplastic Agents - pharmacokinetics | Lung - metabolism | Doxorubicin - administration & dosage | Lung - pathology | TNF-Related Apoptosis-Inducing Ligand - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - chemistry | Administration, Inhalation | Albumins - administration & dosage | Antineoplastic Agents - chemistry | Doxorubicin - pharmacokinetics | Mice, Inbred ICR | Animals | Adsorption | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Aldehydes - chemistry | Albumin | Anthracyclines | Drug therapy | Drug resistance | Lung cancer | Drugs | Drug delivery systems | Drugstores | Respiratory agents | Metastasis | Aldehydes | Vehicles | Pharmacy
Journal Article
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2016, Volume 232, pp. 1 - 8
Near infrared photoimmunotherapy (NIR-PIT), a targeted cancer therapy which uses an antibody-photo absorber conjugate (APC) and near infrared light exposure,... 
Photoimmunotherapy | Drug delivery | Near infrared light | Enhanced permeability and retention effect | Micro distribution | CANCER-CELLS | CHEMOSENSITIVITY | METASTASIS | PHOTODYNAMIC THERAPY | MOUSE | TUMOR | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | ENHANCED PERMEABILITY | IN-VIVO | PHARMACOLOGY & PHARMACY | CYCLE | Carbocyanines - chemistry | Photosensitizing Agents - chemistry | Cetuximab - chemistry | Photosensitizing Agents - therapeutic use | Carbocyanines - administration & dosage | Humans | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Cetuximab - therapeutic use | Photochemotherapy | Photosensitizing Agents - administration & dosage | Neoplasms - therapy | Immunotherapy | Light | Female | Trastuzumab - chemistry | Trastuzumab - therapeutic use | Organophosphorus Compounds - therapeutic use | Organophosphorus Compounds - chemistry | Trastuzumab - administration & dosage | Carbocyanines - therapeutic use | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Cetuximab - administration & dosage | Organophosphorus Compounds - administration & dosage | Microscopy, Fluorescence | Drugs | Viral antibodies | Drug delivery systems | Fluorescence | Antibodies | Permeability | Fluorescence microscopy | Vehicles | Light-emitting diodes | Antineoplastic agents | Antimitotic agents | Cancer | Tumors | micro distribution | drug delivery | photoimmunotherapy | enhanced permeability and retention effect | near infrared light
Journal Article
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 05/2017, Volume 12, pp. 3881 - 3898
Capsaicin has been used in clinical applications for the treatment of pain disorders and inflammatory diseases. Given the strong pungency and high oil/water... 
Prescription optimization | Analgesic | Capsaicin-loaded NLCs | Hot-plate test | Anti-inflammation | Carrageenan-induced paw edema | carrageenan-induced paw edema | analgesic | DRUG-DELIVERY | METHOTREXATE | prescription optimization | NANOSCIENCE & NANOTECHNOLOGY | anti-inflammation | hot-plate test | NANOPARTICLES | IN-VITRO | capsaicin-loaded NLCs | NANOSTRUCTURED LIPID CARRIERS | INFLAMMATION | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | OPTIMIZATION | Fluorescent Dyes - pharmacokinetics | Carbocyanines - pharmacokinetics | Nanocomposites - chemistry | Capsaicin - pharmacology | Carbocyanines - administration & dosage | Capsaicin - chemistry | Drug Carriers - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Drug Carriers - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Capsaicin - administration & dosage | Dose-Response Relationship, Drug | Lipids - chemistry | Female | Fluorescent Dyes - administration & dosage | Rabbits | Rats | Skin Absorption | Rats, Sprague-Dawley | Mice, Inbred ICR | Dinoprostone - metabolism | Particle Size | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Administration, Topical | Dermatitis - drug therapy | Nanocomposites - administration & dosage | Nanoparticles | Drugs | Complications and side effects | Drug delivery systems | Capsaicin | Physiological aspects | Dosage and administration | Research | Properties | Vehicles | Pain | Hydrogels | Lipids | Inflammation | Surfactants | Inflammatory diseases | Apoptosis | Nanolipoidal carriers | Topical application
Journal Article