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Cell Metabolism, ISSN 1550-4131, 02/2017, Volume 25, Issue 2, pp. 386 - 399
Journal Article
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 02/2014, Volume 1843, Issue 2, pp. 372 - 386
(CRNDE) is a novel gene that is activated early in colorectal cancer but whose regulation and functions are unknown. CRNDE transcripts are recognized as long... 
lncRNA | IGF1 | Insulin | CRNDE | Colorectal cancer | Warburg effect | LncRNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IncRNA | CELL-PROLIFERATION | GLUCOSE-TRANSPORT | MUSCLE-CELLS | CELL BIOLOGY | COLON-CANCER | RECTAL-CANCER | COLORECTAL-CANCER | MUTATIONS | CARBOHYDRATE-METABOLISM | EXPRESSION | GROWTH-FACTOR-I | Insulin-Like Growth Factor I - pharmacology | Glucose Transporter Type 4 - metabolism | TOR Serine-Threonine Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | Phosphatidylinositol 3-Kinases - metabolism | RNA, Messenger - metabolism | raf Kinases - metabolism | RNA Interference | Metabolism - drug effects | Insulin-Like Growth Factor II - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Colorectal Neoplasms - metabolism | Metabolism - genetics | Insulin - pharmacology | RNA, Messenger - genetics | RNA, Long Noncoding - genetics | Signal Transduction - genetics | Transcriptome - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Insulin-Like Growth Factor II - metabolism | Gene Expression Regulation - drug effects | Insulin - metabolism | Lactates - metabolism | Signal Transduction - drug effects | Models, Biological | Cell Line, Tumor | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Colorectal Neoplasms - pathology | RNA, Long Noncoding - metabolism | Insulin-Like Growth Factor I - metabolism | Mitogen-Activated Protein Kinases - metabolism | RNA, Small Interfering - metabolism | RNA | Genes | Analysis | Physiological aspects | Glucose | Gene expression | Dextrose | Epigenetic inheritance
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2016, Volume 1861, Issue 6, pp. 491 - 500
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2006, Volume 103, Issue 4, pp. 1006 - 1011
Farnesoid X receptor (FXR) plays an important role in maintaining bile acid and cholesterol homeostasis. Here we demonstrate that FXR also regulates glucose... 
Messenger RNA | Diabetes complications | Glycogen | Liver | Adenoviruses | Mice | Liver glycogen | Insulin | Cholesterols | Blood plasma | GW4064 | triglyceride | glucose | TRIGLYCERIDE LEVELS | MYOCARDIAL-INFARCTION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | GLYCOGEN-SYNTHASE KINASE-3 | farnesoid x receptor-VP16 | INSULIN-RESISTANCE | GENE-EXPRESSION | cholesterol | FARNESOID-X-RECEPTOR | BILE-ACID BIOSYNTHESIS | LIPID HOMEOSTASIS | CARBOHYDRATE-METABOLISM | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear | DNA-Binding Proteins - metabolism | Lipids - chemistry | Glycogen - metabolism | Time Factors | Adenoviridae - genetics | Diabetes Mellitus, Experimental - metabolism | Gluconeogenesis | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Hyperlipidemias - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Etoposide - metabolism | Mice, Transgenic | Models, Statistical | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Triglycerides - metabolism | Hyperglycemia - metabolism | Isoxazoles - pharmacology | Transcription Factors - metabolism | Blotting, Northern | Insulin - metabolism | Animals | 3-Hydroxybutyric Acid - metabolism | Glucose - metabolism | Blood Glucose - metabolism | Glucose metabolism | Control | Genes | Rattus | Homeostasis | Rats | Physiological aspects | Research | Structure | Lipids | Diabetes | Glucose | Metabolism | Rodents | Cholesterol | Index Medicus | Biological Sciences | farnesoid X receptor-VP16
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 31, pp. 25758 - 25769
The early initiation phase of acute inflammation is anabolic and primarily requires glycolysis with reduced mitochondrial glucose oxidation for energy, whereas... 
MACROPHAGE-MEDIATED INFLAMMATION | HOMEOSTASIS | T-CELL MEMORY | METABOLISM | ADIPONECTIN | INSULIN-RESISTANCE | IMMUNOSUPPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTOXIN TOLERANCE | SEPSIS | DIFFERENTIATION | Sirtuin 1 - metabolism | Humans | Monocyte-Macrophage Precursor Cells - immunology | Glucose Transporter Type 1 - metabolism | Monocyte-Macrophage Precursor Cells - metabolism | Leukocytes - immunology | Heat-Shock Proteins - genetics | Monocyte-Macrophage Precursor Cells - physiology | Nicotinamide Phosphoribosyltransferase - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Sepsis - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | NAD - biosynthesis | Fatty Acids - metabolism | Cell Line | Sepsis - immunology | Cytokines - metabolism | Oxidation-Reduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Transcription Factors - genetics | Toll-Like Receptor 4 - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | Adaptation, Physiological - immunology | Animals | Carrier Proteins - metabolism | Energy Metabolism | Lipopolysaccharides - pharmacology | Glucose - metabolism | Glycolysis | Mice | Leukocytes - metabolism | Sirtuins - metabolism | Index Medicus | NAD | Sirtuins | Immunology | Acute Inflammation | Bioenergetics | PGC-1 | Sepsis | HIF-1α | Biosensors | Macrophages | Metabolism
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 19, pp. 20314 - 20326
Hepatic glucokinase (GK) catalyzes the phosphorylation of glucose to glucose 6-phosphate (G6P), a step which is essential for glucose metabolism in liver as... 
FATTY-ACID-SYNTHASE | GLUCOSE-HOMEOSTASIS | CARBOHYDRATE RESPONSE ELEMENT | RAT HEPATOCYTES | STEROL REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | PYRUVATE-KINASE GENE | TRANSCRIPTION FACTOR | CARNITINE-PALMITOYLTRANSFERASE-I | TRANSGENIC MICE | Glucokinase - physiology | Liver - enzymology | Fatty Acid Synthases - metabolism | Immunoblotting | Hepatocytes - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Glycogen - metabolism | Time Factors | CCAAT-Enhancer-Binding Proteins - physiology | Adenoviridae - genetics | Transcription, Genetic | Pentosephosphates - metabolism | RNA - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | DNA-Binding Proteins - physiology | Pyruvate Kinase - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Carbohydrate Metabolism | Cells, Cultured | Gene Expression Regulation | Lipid Metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Nuclear Proteins | Transcription Factors - metabolism | Blotting, Northern | Animals | Proteins - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Glucose - metabolism | Mice | Kinetics | Sterol Regulatory Element Binding Protein 1 | Glucose-6-Phosphate - metabolism | Acetyl-CoA Carboxylase - metabolism | Microscopy, Fluorescence | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, pp. e0148089 - e0148089
Cellular energy regulation relies on complex signaling pathways that respond to fuel availability and metabolic demands. Dysregulation of these networks is... 
LIFE-SPAN | PPAR-ALPHA | ENERGY | FATTY-ACID-COMPOSITION | GLUCOSE | MULTIDISCIPLINARY SCIENCES | RECEPTOR NHR-49 | GENE-EXPRESSION | C-ELEGANS | LACTIC-ACIDOSIS | DIETARY RESTRICTION | Humans | Caenorhabditis elegans Proteins - metabolism | Oxygen - metabolism | Protein Subunits - metabolism | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Cell Respiration - drug effects | Transcription, Genetic | Energy Metabolism - genetics | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Protein Subunits - genetics | Caenorhabditis elegans - metabolism | Signal Transduction | Caenorhabditis elegans - genetics | Lactic Acid - metabolism | Metformin - pharmacology | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mitochondria - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Longevity - genetics | Mitochondria - drug effects | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Caenorhabditis elegans - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Oxygen Consumption - drug effects | Glucose - metabolism | Caenorhabditis elegans Proteins - genetics | Energy Metabolism - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Cell metabolism | Caenorhabditis elegans | Genetic aspects | Research | Protein kinases | Oxidative stress | Energy metabolism | Regulators | Transcription factors | Phosphorylation | Transcription | Oxidative metabolism | Homeostasis | Lipids | Kinases | AMP-activated protein kinase | Protein turnover | Proteins | Mitochondria | Energy | Evolutionary conservation | Physiology | Catalysis | Worms | Enzymes | AMP | Oxygen consumption | Fluxes | Metabolism | Mammals | Gene expression | Fatty acids | Strain | Signaling | Nematodes | Glycolysis | Diabetes | Lactic acid | Metformin | Metabolic disorders | Index Medicus
Journal Article
1966, ISBN 0121819418, Volume 9,41,42,89,90., 5 v.
Book
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6090, pp. 96 - 100
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial... 
Yeasts | Mitochondria | Diet | Plasmids | Drosophila | REPORTS | Amino acids | Oxidation | Respiration | Sugars | Medical schools | RAT-LIVER | TRANSPORT | COMPLEX | MECHANISM | IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | Metabolomics | Humans | Molecular Sequence Data | Mitochondrial Proteins - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Anion Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - genetics | Drosophila melanogaster - metabolism | Saccharomyces cerevisiae - metabolism | Amino Acids - metabolism | Biological Transport | Mitochondrial Proteins - metabolism | Pyruvic Acid - metabolism | Amino Acid Sequence | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Oxidation-Reduction | Carbohydrate Metabolism | Mitochondria - metabolism | Drosophila Proteins - chemistry | Saccharomyces cerevisiae Proteins - genetics | Anion Transport Proteins - metabolism | Citric Acid Cycle | Mitochondrial Membranes - metabolism | Point Mutation | Animals | Drosophila melanogaster - chemistry | Mitochondrial Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Drosophila Proteins - genetics | Anion Transport Proteins - genetics | Saccharomyces cerevisiae Proteins - chemistry | Cell metabolism | Pyruvates | Chemical properties | Research | Molecular biology | Proteins | Yeast | Metabolism | Index Medicus | Carriers | Human | Bacteria | Transport | Transporter
Journal Article