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1999
eJournal
Diabetes, obesity & metabolism, ISSN 1462-8902, 1999
Journal
Diabetes/metabolism reviews, ISSN 0742-4221, 1985
Journal
Journal of hepatology, ISSN 0168-8278, 2011, Volume 54, Issue 4, pp. 773 - 794
... when the administered daily dosage is higher than 50 mg or when the drug undergoes significant liver metabolism [4]. The mechanisms of DILI are not always known... 
Gastroenterology and Hepatology | Drugs | Obesity | Oxidative stress | Mitochondria | Cell death | Lipids | Hepatotoxicity | Steatosis | TRIGLYCERIDE TRANSFER PROTEIN | DNA-POLYMERASE-GAMMA | PREGNANE X-RECEPTOR | PROLIFERATOR-ACTIVATED RECEPTOR | HEPATIC CYTOCHROME-P450 2E1 | ELEMENT-BINDING PROTEINS | FATTY-ACID OXIDATION | CONSTITUTIVE ANDROSTANE RECEPTOR | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RELATED PARAMETERS | GASTROENTEROLOGY & HEPATOLOGY | Carbohydrate Metabolism - drug effects | Reactive Oxygen Species - metabolism | Mitochondria, Liver - metabolism | Humans | Leptin - metabolism | Oxidative Phosphorylation - drug effects | Adipose Tissue - metabolism | Adiponectin - metabolism | Hepatitis C - complications | Cell Death - drug effects | Fatty Acids - metabolism | Chemical and Drug Induced Liver Injury - etiology | Diabetes Mellitus, Type 2 - complications | Genetic Predisposition to Disease | Fatty Liver - metabolism | Oxidation-Reduction | Obesity - complications | Insulin Resistance | Mitochondrial Membrane Transport Proteins - drug effects | Chemical and Drug Induced Liver Injury - genetics | Mitochondria, Liver - drug effects | Animals | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | Lipid Metabolism - drug effects | Alcoholic Intoxication - complications | Genome, Mitochondrial | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Fatty Liver - etiology | Divalproex | Liver diseases | Thiols | Liver | Cytochrome P-450 | Mitochondrial DNA | Triglycerides | Stavudine | Permeability | Valproic acid | Fatty acids | Cells | Carnitine | Metabolites | Glutathione transferase | Acetaminophen | Physiological aspects | DNA polymerases | Health aspects | Zidovudine | Index Medicus | Reactive Oxygen Species | Fatty Acids | Adiponectin | Mitochondria, Liver | Life Sciences | Mitochondrial Membrane Transport Proteins | Cell Death | Diabetes Mellitus, Type 2 | Adipose Tissue | Alcoholic Intoxication | Hépatology and Gastroenterology | Oxidative Phosphorylation | Carbohydrate Metabolism | Lipid Metabolism | Drug-Induced Liver Injury | Fatty Liver | Human health and pathology | Energy Metabolism | Leptin | Hepatitis C
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2006, Volume 103, Issue 4, pp. 1006 - 1011
.... Here we demonstrate that FXR also regulates glucose metabolism. Activation of FXR by the synthetic agonist GW4064 or hepatic overexpression of constitutively active... 
Messenger RNA | Diabetes complications | Glycogen | Liver | Adenoviruses | Mice | Liver glycogen | Insulin | Cholesterols | Blood plasma | GW4064 | triglyceride | glucose | TRIGLYCERIDE LEVELS | MYOCARDIAL-INFARCTION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | GLYCOGEN-SYNTHASE KINASE-3 | farnesoid x receptor-VP16 | INSULIN-RESISTANCE | GENE-EXPRESSION | cholesterol | FARNESOID-X-RECEPTOR | BILE-ACID BIOSYNTHESIS | LIPID HOMEOSTASIS | CARBOHYDRATE-METABOLISM | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear | DNA-Binding Proteins - metabolism | Lipids - chemistry | Glycogen - metabolism | Time Factors | Adenoviridae - genetics | Diabetes Mellitus, Experimental - metabolism | Gluconeogenesis | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Hyperlipidemias - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Etoposide - metabolism | Mice, Transgenic | Models, Statistical | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Triglycerides - metabolism | Hyperglycemia - metabolism | Isoxazoles - pharmacology | Transcription Factors - metabolism | Blotting, Northern | Insulin - metabolism | Animals | 3-Hydroxybutyric Acid - metabolism | Glucose - metabolism | Blood Glucose - metabolism | Glucose metabolism | Control | Genes | Rattus | Homeostasis | Rats | Physiological aspects | Research | Structure | Biological Sciences | farnesoid X receptor-VP16
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2004, Volume 279, Issue 19, pp. 20314 - 20326
...), a step which is essential for glucose metabolism in liver as well as for the induction of glycolytic and lipogenic genes... 
FATTY-ACID-SYNTHASE | GLUCOSE-HOMEOSTASIS | CARBOHYDRATE RESPONSE ELEMENT | RAT HEPATOCYTES | STEROL REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | PYRUVATE-KINASE GENE | TRANSCRIPTION FACTOR | CARNITINE-PALMITOYLTRANSFERASE-I | TRANSGENIC MICE | Glucokinase - physiology | Liver - enzymology | Fatty Acid Synthases - metabolism | Immunoblotting | Hepatocytes - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Glycogen - metabolism | Time Factors | CCAAT-Enhancer-Binding Proteins - physiology | Adenoviridae - genetics | Transcription, Genetic | Pentosephosphates - metabolism | RNA - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | DNA-Binding Proteins - physiology | Pyruvate Kinase - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Carbohydrate Metabolism | Cells, Cultured | Gene Expression Regulation | Lipid Metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Nuclear Proteins | Transcription Factors - metabolism | Blotting, Northern | Animals | Proteins - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Glucose - metabolism | Mice | Kinetics | Sterol Regulatory Element Binding Protein 1 | Glucose-6-Phosphate - metabolism | Acetyl-CoA Carboxylase - metabolism | Microscopy, Fluorescence | RNA, Small Interfering - metabolism
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2009, Volume 54, Issue 20, pp. 1891 - 1898
Journal Article
The New phytologist, ISSN 0028-646X, 2015, Volume 205, Issue 1, pp. 240 - 254
Overexpression of bacterial γ-glutamylcysteine synthetase in the cytosol of × produces higher glutathione (GSH) concentrations in leaves, thereby indicating... 
Full papers | Cadmium | Leaves | Messenger RNA | Genes | Plant roots | Plants | Root tips | Transgenic plants | Genotypes | antioxidant | plasma membrane H+‐ATPase | glutathione | ion flux | phytoremediation | Populus | oxidative stress | cadmium (Cd) | Ion flux | Oxidative stress | Cadmium (Cd) | ATPase | Plasma membrane H | Antioxidant | Glutathione | Phytoremediation | ARABIDOPSIS-THALIANA | PHYTOCHELATIN SYNTHASE | PHYSIOLOGICAL-RESPONSES | GLUTATHIONE SYNTHESIS | TRANSCRIPTIONAL RESPONSES | PLANT SCIENCES | plasma membrane H+-ATPase | POPULUS X CANESCENS | BRASSICA-NAPUS | GENE-EXPRESSION | HEAVY-METAL RESISTANCE | LONG-DISTANCE TRANSPORT | Inactivation, Metabolic | Reactive Oxygen Species - metabolism | Calcium - metabolism | Genes, Plant | Antioxidants - metabolism | Carbohydrate Metabolism - genetics | Populus - genetics | Cadmium - metabolism | RNA, Messenger - metabolism | Sulfhydryl Compounds - metabolism | Biological Transport | Plants, Genetically Modified | Populus - metabolism | Gene Expression Regulation, Plant | Superoxides - metabolism | Dipeptides - metabolism | Principal Component Analysis | Hydrogen - metabolism | Escherichia coli - enzymology | Plant Roots - metabolism | RNA, Messenger - genetics | Wood - metabolism | Plant Leaves - metabolism | Models, Biological | Plant Bark - metabolism | Populus - growth & development
Journal Article