X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1660) 1660
Publication (153) 153
Book Review (20) 20
Book Chapter (15) 15
Book / eBook (6) 6
Newspaper Article (2) 2
Dissertation (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1001) 1001
humans (892) 892
chemistry, medicinal (811) 811
biochemistry & molecular biology (620) 620
structure-activity relationship (605) 605
carbonic anhydrase inhibitors - chemical synthesis (604) 604
carbonic anhydrase (601) 601
carbonic anhydrase inhibitors - pharmacology (599) 599
carbonic anhydrase inhibitors - chemistry (544) 544
molecular structure (454) 454
animals (452) 452
carbonic anhydrases - metabolism (438) 438
sulfonamides - chemistry (412) 412
sulfonamides (402) 402
sulfonamides - chemical synthesis (380) 380
sulfonamides - pharmacology (374) 374
chemistry, organic (361) 361
derivatives (326) 326
carbonic-anhydrase inhibitors (294) 294
dose-response relationship, drug (270) 270
sulfonamide (216) 216
carbonic anhydrase ii - antagonists & inhibitors (204) 204
chemistry, multidisciplinary (203) 203
cancer (198) 198
models, molecular (197) 197
carbonic anhydrases - chemistry (196) 196
drug design (194) 194
therapeutic applications (181) 181
carbonic anhydrase ii - metabolism (179) 179
inhibitors (177) 177
enzymes (175) 175
isoenzymes - antagonists & inhibitors (174) 174
design (172) 172
carbonic-anhydrase (170) 170
carbonic anhydrase i - antagonists & inhibitors (154) 154
antineoplastic agents - pharmacology (150) 150
analysis (147) 147
isozyme-ii (145) 145
binding (140) 140
kinetics (139) 139
carbonic anhydrase ix (138) 138
pharmacology & pharmacy (136) 136
antineoplastic agents - chemical synthesis (134) 134
chemistry (133) 133
carbonic anhydrase i - metabolism (131) 131
drug discovery (124) 124
isoenzymes - metabolism (124) 124
hypoxia (121) 121
expression (120) 120
activators (119) 119
antineoplastic agents - chemistry (119) 119
mice (118) 118
protein binding (115) 115
agents (111) 111
cell line, tumor (108) 108
proteins (108) 108
crystal-structure (107) 107
biological evaluation (105) 105
isoenzymes (105) 105
antigens, neoplasm - metabolism (100) 100
crystallography, x-ray (98) 98
organic chemistry (98) 98
binding sites (93) 93
therapeutics. pharmacology (91) 91
inhibition (90) 90
male (90) 90
tumors (90) 90
in-vitro (89) 89
research (89) 89
enzyme inhibition (86) 86
acetazolamide (82) 82
discovery (82) 82
carbonic anhydrase inhibitors (81) 81
ligands (81) 81
research article (81) 81
molecular docking simulation (80) 80
synthesis (80) 80
xii (80) 80
carbonic anhydrase ii - chemistry (78) 78
anticancer (77) 77
glaucoma (75) 75
carbonic anhydrase inhibitors - metabolism (74) 74
female (73) 73
drug screening assays, antitumor (72) 72
purification (70) 70
enzyme inhibitors - pharmacology (69) 69
inhibitor (68) 68
medicine (68) 68
biology (67) 67
carbon dioxide (67) 67
potent (67) 67
acetylcholinesterase (65) 65
drugs (65) 65
moieties (64) 64
enzyme inhibitors - chemistry (63) 63
selective inhibitors (63) 63
antigens, neoplasm - chemistry (62) 62
cell proliferation - drug effects (62) 62
erythrocytes - enzymology (62) 62
amino acid sequence (61) 61
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 6/2014, Volume 29, Issue 3, pp. 379 - 387
Abstract Recent advances in microbial genomics, synthetic organic chemistry and X-ray crystallography provided opportunities to identify novel antibacterial... 
carbonic anhydrase | Antibacterial | dihydropteroate synthase | sulfa drug | trimethoprim | dihydrofolate reductase | Trimethoprim | Dihydropteroate synthase | Sulfa drug | Dihydrofolate reductase | Carbonic anhydrase | HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHATE | CHEMISTRY, MEDICINAL | BACTERIUM VIBRIO-CHOLERAE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SULFONAMIDE RESISTANCE | ATMOSPHERIC CO2 | SOIL-MICROORGANISMS | PLASMODIUM-FALCIPARUM | STAPHYLOCOCCUS-AUREUS | HELICOBACTER-PYLORI | ENZYMATIC SYNTHESIS | Trimethoprim - chemical synthesis | Bacterial Proteins - antagonists & inhibitors | Trimethoprim - pharmacology | Tetrahydrofolate Dehydrogenase - chemistry | Antimetabolites - chemical synthesis | Dihydropteroate Synthase - antagonists & inhibitors | Bacteria - drug effects | Bacterial Proteins - chemistry | Enzyme Inhibitors - pharmacology | Carbonic Anhydrase Inhibitors - chemical synthesis | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrases - chemistry | Enzyme Inhibitors - chemical synthesis | Anti-Bacterial Agents - chemical synthesis | Trimethoprim - analogs & derivatives | Dihydropteroate Synthase - chemistry | Bacteria - enzymology | Anti-Bacterial Agents - pharmacology | Folic Acid Antagonists - chemical synthesis | Sulfanilamides - chemical synthesis | Folic Acid Antagonists - pharmacology | Antimetabolites - pharmacology | Sulfanilamides - pharmacology
Journal Article
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 12/2012, Volume 27, Issue 6, pp. 759 - 772
Inhibition of the metalloenzyme carbonic anhydrase (CA; EC 4.2.1.1) has pharmacologic applications in the field of anti-glaucoma, anti-convulsant and... 
sulphonamide | x-ray crystallography | imaging of hypoxic tumours | Carbonic anhydrase | glaucoma | anti-cancer agent | dithiocarbamate | Glaucoma | X-ray crystallography | Anti-cancer agent | Dithiocarbamate | Sulphonamide | Imaging of hypoxic tumours | MYCOBACTERIUM-TUBERCULOSIS | INCORPORATING 1,3,5-TRIAZINE MOIETIES | CHEMISTRY, MEDICINAL | ACTIVE-SITE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | THERAPEUTIC APPLICATIONS | CRYSTALLOGRAPHIC ANALYSIS | PH-DEPENDENT ACTIVITY | X-RAY | ISOZYME-II | CRYPTOCOCCUS-NEOFORMANS | Fungal Proteins - chemistry | Anti-Infective Agents - pharmacology | Humans | Bacteria - drug effects | Bacterial Proteins - chemistry | Crystallography, X-Ray | Fungal Proteins - antagonists & inhibitors | Isoenzymes - chemistry | Structure-Activity Relationship | Carbonic Anhydrases - chemistry | Carbonic Anhydrases - metabolism | Bacteria - growth & development | Thiocarbamates - pharmacology | Isoenzymes - metabolism | Fungi - growth & development | Bacterial Proteins - antagonists & inhibitors | Catalytic Domain | Fungi - drug effects | Carbonic Anhydrase Inhibitors - chemical synthesis | Carbonic Anhydrase Inhibitors - pharmacology | Sulfonamides - pharmacology | Drug Discovery | Anti-Infective Agents - chemical synthesis | Sulfonamides - chemical synthesis | Thiocarbamates - chemical synthesis | Bacterial Proteins - metabolism | Molecular Docking Simulation | Isoenzymes - antagonists & inhibitors | Fungal Proteins - metabolism
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 11/2016, Volume 31, Issue sup2, pp. 79 - 85
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2015, Volume 23, Issue 13, pp. 3592 - 3602
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2014, Volume 22, Issue 13, pp. 3537 - 3543
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 521 - 530
Journal Article