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1. Full Text Carbonic anhydrase inhibitors
by Supuran, Claudiu T
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 06/2010, Volume 20, Issue 12, pp. 3467 - 3474
Antimalarial | Antiglaucoma | Antifungal | Sulfonamide | Anticonvulsant | Anticancer agent | Antibacterial | Coumarin | Anti-pain | Fullerene | Tumor diagnostics | Carbonic anhydrase | Diuretics | Sulfamate | Antiobesity | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Eye | Analgesics | General and cellular metabolism. Vitamins | Pharmacology. Drug treatments | Biological and medical sciences | Anticonvulsants. Antiepileptics. Antiparkinson agents | Medical sciences | Neuropharmacology | Animals | Carbonic Anhydrase Inhibitors - chemistry | Drug Therapy | Carbonic Anhydrases - isolation & purification | Carbonic Anhydrases - therapeutic use | Carbonic Anhydrases - chemistry | Carbonic Anhydrase Inhibitors - therapeutic use | Histidine | Sulfonamides | Ophthalmic drugs | Index Medicus
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2. Full Text Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases
by Del Prete, Sonia and Vullo, Daniela and Fisher, Gillian M and Andrews, Katherine T and Poulsen, Sally-Ann and Capasso, Clemente and Supuran, Claudiu T
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 09/2014, Volume 24, Issue 18, pp. 4389 - 4396
η-CA-class enzyme | Plasmodium falciparum | Inhibitor | Carbonic anhydrase | Anion | Plasmodium falciparum - enzymology | Amino Acid Sequence | Carbonic Anhydrase Inhibitors - chemistry | Humans | Molecular Sequence Data | Carbonic Anhydrase Inhibitors - chemical synthesis | Structure-Activity Relationship | Carbonic Anhydrase Inhibitors - pharmacology | Phylogeny | Zinc - chemistry | Drug Discovery | Carbonic Anhydrases - metabolism | Dose-Response Relationship, Drug | Sequence Alignment | Isoenzymes - metabolism | Organometallic Compounds - chemical synthesis | Organometallic Compounds - chemistry | Plasmodium falciparum - metabolism | Molecular Structure | Isoenzymes - antagonists & inhibitors | Organometallic Compounds - pharmacology | Index Medicus
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3. Full Text Carbonic anhydrase inhibitors: The β-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors
by Nishimori, Isao and Minakuchi, Tomoko and Kohsaki, Takuhiro and Onishi, Saburo and Takeuchi, Hiroaki and Vullo, Daniela and Scozzafava, Andrea and Supuran, Claudiu T
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2007, Volume 17, Issue 13, pp. 3585 - 3594
Sulfonamide | Carbonic anhydrase | Helicobacter pylori | Sulfamate | Enzyme inhibitor | β-class enzyme | Catalytic/inhibition mechanism | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Medical sciences | Antibacterial agents | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Recombinant Proteins - metabolism | Amino Acid Sequence | Chemistry, Pharmaceutical - methods | Sulfonamides - antagonists & inhibitors | Sulfonamides - chemistry | Humans | Enzyme Inhibitors - pharmacology | Stomach Ulcer - drug therapy | Molecular Sequence Data | Carbonic Anhydrase Inhibitors - chemical synthesis | Carbonic Anhydrase Inhibitors - pharmacology | Stomach Neoplasms - drug therapy | Carbonic Anhydrases - chemistry | Enzyme Inhibitors - chemical synthesis | Sequence Homology, Amino Acid | Helicobacter pylori - enzymology | Cloning, Molecular | Drug Design | Index Medicus
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4. Full Text (In)organic anions as carbonic anhydrase inhibitors
by De Simone, Giuseppina and Supuran, Claudiu T
Journal of inorganic biochemistry, ISSN 0162-0134, 06/2012, Volume 111, pp. 117 - 129
X-ray crystallography | Enzyme inhibitor | Metal complexing anion | Carbonic anhydrase | Anion | Inhibition mechanism | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Protein Structure, Tertiary | Anions - pharmacology | Carbonic Anhydrase Inhibitors - chemistry | Zinc - metabolism | Humans | Models, Molecular | Isoenzymes - chemistry | Anions - chemistry | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrases - chemistry | Zinc - chemistry | Carbonic Anhydrases - metabolism | Animals | Biocatalysis - drug effects | Isoenzymes - metabolism | Enzymes | Chemical inhibitors | Enzyme inhibitors | Corals | Sulfonamides | Ophthalmic drugs | Index Medicus
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5. Full Text Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II–trithiocarbonate adduct—An inhibitor mimicking the sulfonamide and urea binding to the enzyme
by Temperini, Claudia and Scozzafava, Andrea and Supuran, Claudiu T
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2010, Volume 20, Issue 2, pp. 474 - 478
X-ray crystallography | Urea | Trithiocarbonate | Sulfonamide | Carbonic anhydrase | Anion inhibitor | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Catalytic Domain | Sulfonamides - chemistry | Carbonic Anhydrase Inhibitors - chemistry | Thiones - chemistry | Carbonic Anhydrase II - metabolism | Crystallography, X-Ray | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrase II - antagonists & inhibitors | Urea - chemistry | Hydrogen Bonding | Protein Binding | Thiones - pharmacology | Binding Sites | Enzymes | Chemical properties | Sulfonamides | Ophthalmic drugs | Index Medicus
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6. Full Text Carbonic anhydrase inhibitors
by Supuran, Claudiu T and Scozzafava, Andrea and Casini, Angela
Medicinal research reviews, ISSN 0198-6325, 03/2003, Volume 23, Issue 2, pp. 146 - 189
Glaucoma | Sulfonamide | Carbonic anhydrase | Anticanceragent | Diagnostic tool | Isozymes | X-ray | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Animals | Carbonic Anhydrase Inhibitors - chemistry | Humans | Drug Design | Models, Molecular | Carbonic Anhydrase Inhibitors - pharmacology | Catalysis | Index Medicus
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7. Full Text Discovery of potent carbonic anhydrase and acetylcholinesterase inhibitors: 2-aminoindan β-lactam derivatives
by Genç, Hayriye and Kalin, Ramazan and Köksal, Zeynep and Sadeghian, Nastaran and Kocyigit, Umit M and Zengin, Mustafa and Gülçin, İlhami and Özdemir, Hasan
International journal of molecular sciences, ISSN 1661-6596, 10/2016, Volume 17, Issue 10, pp. 1736 - 1736
Enzyme inhibitionenzyme purification | Carbonic anhydrase | 2-azetidinone | Acetylcholinesterase | β-lactam | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Indans - chemistry | Carbonic Anhydrase Inhibitors - chemistry | Humans | Cholinesterase Inhibitors - chemistry | Neurotransmitter Agents - metabolism | Acetylcholine - metabolism | Azetidines - chemistry | beta-Lactams - chemistry | Acetylcholinesterase - metabolism | Carbonic Anhydrases - metabolism | carbonic anhydrase | acetylcholinesterase | enzyme purification | enzyme inhibition
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8.