X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (11734) 11734
Book Review (982) 982
Publication (770) 770
Book Chapter (128) 128
Conference Proceeding (69) 69
Dissertation (21) 21
Book / eBook (14) 14
Newspaper Article (9) 9
Government Document (4) 4
Web Resource (2) 2
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (8421) 8421
humans (3850) 3850
animals (3818) 3818
biochemistry & molecular biology (3515) 3515
carbonic anhydrase (3128) 3128
carbonic anhydrases - metabolism (2385) 2385
carbonic-anhydrase (2191) 2191
chemistry, medicinal (1718) 1718
carbonic anhydrase inhibitors - pharmacology (1353) 1353
kinetics (1294) 1294
carbonic anhydrases - chemistry (1275) 1275
proteins (1269) 1269
enzymes (1222) 1222
carbonic anhydrase inhibitors - chemistry (1068) 1068
chemistry, multidisciplinary (1037) 1037
structure-activity relationship (1034) 1034
hydrogen-ion concentration (1024) 1024
analysis (1016) 1016
male (992) 992
sulfonamides (952) 952
chemistry, organic (942) 942
models, molecular (935) 935
molecular structure (824) 824
binding sites (811) 811
amino acid sequence (802) 802
female (792) 792
cattle (778) 778
chemistry (774) 774
carbonic anhydrases - genetics (749) 749
protein binding (749) 749
molecular sequence data (744) 744
expression (742) 742
sulfonamides - chemistry (741) 741
binding (732) 732
research (727) 727
mice (711) 711
derivatives (691) 691
rats (690) 690
sulfonamides - pharmacology (681) 681
carbonic-anhydrase inhibitors (675) 675
biophysics (672) 672
crystal-structure (668) 668
ligands (618) 618
carbon dioxide (604) 604
protein conformation (601) 601
carbonic anhydrase inhibitors - chemical synthesis (599) 599
catalysis (591) 591
zinc (589) 589
inhibitors (588) 588
cell biology (580) 580
cancer (571) 571
pharmacology & pharmacy (549) 549
physiology (535) 535
protein (527) 527
chemistry, physical (524) 524
erythrocytes - enzymology (510) 510
carbonic anhydrase ii - metabolism (509) 509
sulfonamide (495) 495
crystallography, x-ray (494) 494
inhibition (473) 473
physiological aspects (454) 454
active-site (453) 453
chemistry, inorganic & nuclear (451) 451
drug design (446) 446
carbonic anhydrases (445) 445
carbonic anhydrases - analysis (443) 443
article (441) 441
carbonic anhydrase ix (441) 441
isoenzymes - metabolism (433) 433
carbon dioxide - metabolism (427) 427
biochemical research methods (426) 426
acetazolamide (425) 425
hypoxia (422) 422
dose-response relationship, drug (420) 420
carbonic-anhydrase-ii (418) 418
mechanism (409) 409
carbonic anhydrase inhibitors (407) 407
biochemistry (404) 404
life sciences (403) 403
carbonic anhydrases - blood (393) 393
design (391) 391
protein folding (391) 391
carbonic anhydrase ii - chemistry (385) 385
sulfonamides - chemical synthesis (383) 383
gene expression (368) 368
photosynthesis (365) 365
chemistry, analytical (362) 362
carbonic anhydrase ii - antagonists & inhibitors (357) 357
cells (357) 357
chemical properties (357) 357
thermodynamics (351) 351
escherichia-coli (350) 350
therapeutic applications (345) 345
biotechnology & applied microbiology (344) 344
plant sciences (332) 332
metabolism (318) 318
multidisciplinary sciences (318) 318
acetazolamide - pharmacology (313) 313
biology (312) 312
isozyme-ii (312) 312
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (11742) 11742
German (41) 41
French (40) 40
Chinese (29) 29
Russian (20) 20
Japanese (14) 14
Czech (6) 6
Italian (3) 3
Lithuanian (3) 3
Polish (3) 3
Portuguese (3) 3
Hungarian (2) 2
Korean (2) 2
Swedish (2) 2
Dutch (1) 1
Romanian (1) 1
Serbian (1) 1
Spanish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2018, Volume 151, pp. 363 - 375
Two series of 2-benzylpiperazines have been prepared and tested for the inhibition of physiologically relevant isoforms of human carbonic anhydrases (hCA, EC... 
Glaucoma | Enzyme inhibitors | Carbonic anhydrase | Enantioselectivity | Piperazine | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | SULFONAMIDES | MOIETIES | DISCOVERY | BENZENESULFONAMIDES | GENERATION | DERIVATIVES | TOOL | Intraocular Pressure - drug effects | Carbonic Anhydrase Inhibitors - chemistry | Stereoisomerism | Humans | Carbonic Anhydrase II - metabolism | Crystallography, X-Ray | Male | Piperazines - chemistry | Carbonic Anhydrase I - metabolism | Carbonic Anhydrases - chemistry | Carbonic Anhydrase II - antagonists & inhibitors | Carbonic Anhydrases - metabolism | Carbonic Anhydrase IV - metabolism | Carbonic Anhydrase IX - metabolism | Glaucoma - metabolism | Glaucoma - physiopathology | Carbonic Anhydrase Inhibitors - therapeutic use | Carbonic Anhydrase IX - antagonists & inhibitors | Rabbits | Glaucoma - drug therapy | Carbonic Anhydrase Inhibitors - chemical synthesis | Piperazines - therapeutic use | Carbonic Anhydrase I - chemistry | Carbonic Anhydrase Inhibitors - pharmacology | Piperazines - pharmacology | Animals | Carbonic Anhydrase IV - chemistry | Carbonic Anhydrase I - antagonists & inhibitors | Carbonic Anhydrase IX - chemistry | Piperazines - chemical synthesis | Molecular Docking Simulation | Carbonic Anhydrase IV - antagonists & inhibitors | Carbonic Anhydrase II - chemistry | Benzylpiperazine | Functional foods | Analysis | Enantiomers | Nitrogen | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 38, pp. 16233 - 16238
Carbonic anhydrase (CA) IX is a plasma membrane-associated member of the α-CA enzyme family, which is involved in solid tumor acidification. It is a marker of... 
Enzymes | Molecules | Active sites | Memory interference | Crystals | Cell adhesion | Hypoxia | Dimers | Crystal structure | Tumors | CA-IX | ISOZYMES | PROTEIN-TYROSINE-PHOSPHATASES | MULTIDISCIPLINARY SCIENCES | RESOLUTION | INTRACELLULAR PH | EXTRACELLULAR DOMAIN | E-CADHERIN | PROTON-TRANSFER | HYPOXIA | REFINED STRUCTURE | Protons | Carbon Dioxide - chemistry | Carbonic Anhydrases - genetics | Humans | Protein Multimerization | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Carbonic Anhydrases - chemistry | Antigens, Neoplasm - chemistry | Carbonic Anhydrases - metabolism | Disulfides - chemistry | Enzyme Inhibitors - chemistry | Drug Design | Water - chemistry | Antigens, Neoplasm - metabolism | Bicarbonates - chemistry | Carbonic Anhydrase IX | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Antigens, Neoplasm - genetics | Catalytic Domain | Carbon Dioxide - metabolism | Enzyme Inhibitors - metabolism | Crystallization | Enzyme Inhibitors - pharmacology | Water - metabolism | Models, Molecular | Neoplasms - enzymology | Recombinant Proteins - chemistry | Neoplasms - drug therapy | Sequence Homology, Amino Acid | Bicarbonates - metabolism | Protein Conformation | Kinetics | Neoplasms - pathology | Hydrogen-Ion Concentration | Structure | Proteins | Membranes | Molecular structure | Chemical compounds | Cell adhesion & migration | Index Medicus | Biological Sciences
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 09/2015, Volume 23, Issue 17, pp. 5311 - 5318
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2017, Volume 25, Issue 14, pp. 3714 - 3718
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 521 - 530
Journal Article
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 02/2004, Volume 186, Issue 3, pp. 623 - 630
Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PCC7942 | GENE | CYANOBACTERIUM SYNECHOCOCCUS UTEX-625 | CARBOXYLASE/OXYGENASE | MICROBIOLOGY | CO2 CONCENTRATING MECHANISMS | INORGANIC CARBON | THIOBACILLUS-NEAPOLITANUS | EXPRESSION | PROCHLOROCOCCUS | SYNECH