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1. Introduction to carcinogen hazards
: an outline of chemical carcinogens, hazards and test methods, with data and assessments on 78 miscellaneous chemicals
by Searle, Charles E., 1922 and Teale, Jennifer and University of Birmingham. Dept. of Cancer Studies
1988, ISBN 9780704409934, iii, 157
Handbooks, manuals, etc | Carcinogenicity testing | Carcinogens
Book
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2. Full Text Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010
by Adler, Sarah and Basketter, David and Creton, Stuart and Pelkonen, Olavi and van Benthem, Jan and Zuang, Valerie and Andersen, Klaus Ejner and Angers-Loustau, Alexane and Aptula, Aynur and Bal-Price, Anna and Benfenati, Emilio and Bernauer, Ulrike and Bessems, Jos G. M and Bois, Frederic Y and Boobis, Alan and Brandon, Esther and Bremer, Susanne and Broschard, Thomas and Casati, Silvia and Coecke, Sana and Corvi, Raffaella and Cronin, Mark and Daston, George and Dekant, Wolfgang and Felter, Susan and Grignard, Elise and Gundert-Remy, Ursula and Heinonen, Tuula and Kimber, Ian and Kleinjans, Jos and Komulainen, Hannu and Kreiling, Reinhard and Kreysa, Joachim and Leite, Sofia Batista and Loizou, George and Maxwell, Gavin and Mazzatorta, Paolo and Munn, Sharon and Pfuhler, Stefan and Phrakonkham, Pascal and Piersma, Aldert H and Poth, Albrecht and Prieto, Pilar and Repetto, Guillermo and Rogiers, Vera and Schoeters, Greet and Schwarz, Michael and Serafimova, Rositsa and Tahti, Hanna and Testai, Emanuela and van Delft, Joost and van Loveren, Henk and Vinken, Mathieu and Worth, Anew and Zaldivar, Jose-Manuel
Archives of Toxicology, ISSN 0340-5761, 05/2011, Volume 85, Issue 5, pp. 367 - 485
The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics on the market in Europe after 2013. In that context, the European... 
Toxicokinetics | Repeated dose toxicity | Carcinogenicity | Alternative methods | Reproductive toxicity | Skin sensitisation | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Biomedicine general | STEM-CELL TEST | IN-VIVO EXTRAPOLATION | LYMPH-NODE ASSAY | PIG MAXIMIZATION TEST | QUANTITATIVE RISK-ASSESSMENT | TOXICOLOGICAL CONCERN TTC | VITRO GENOTOXICITY TESTS | INCORPORATING MOLECULAR FLEXIBILITY | TOXICOLOGY | DISCRIMINATE RODENT CARCINOGENS | VOLATILE ORGANIC-COMPOUNDS | Risk Assessment - methods | Guidelines as Topic | Reproducibility of Results | Carcinogenicity Tests - methods | Humans | Animal Testing Alternatives - standards | Biological Availability | Toxicity Tests - trends | Animal Testing Alternatives - trends | Animals | Consumer Product Safety - legislation & jurisprudence | Cosmetics - standards | European Union | Toxicity Tests - methods | Risk Assessment - trends | Skin - drug effects | Animal experimentation | Medical colleges | Allergy | Environmental health | Green technology | Cosmetics | Scientists | Allergic reaction | Consulting services | Methods | Public health | Cosmetics industry | Product testing | Laboratory animals | Toxicity | Life Sciences | Toxicology | Environmental Sciences
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3. Full Text IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)
by MacGregor, James T and Frötschl, Roland and White, Paul A and Crump, Kenny S and Eastmond, David A and Fukushima, Shoji and Guérard, Melanie and Hayashi, Makoto and Soeteman-Hernández, Lya G and Kasamatsu, Toshio and Levy, Dan D and Morita, Takeshi and Müller, Lutz and Schoeny, Rita and Schuler, Maik J and Thybaud, Véronique and Johnson, George E
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, ISSN 1383-5718, 05/2015, Volume 783, pp. 55 - 65
This report summarizes the discussion, conclusions, and points of consensus of the IWGT Working Group on Quantitative Approaches to Genetic Toxicology Risk... 
Points of departure | Quantitative risk assessment | Genotoxicity | Benchmark dose | PREDICTING RODENT CARCINOGENICITY | LIMITS | THRESHOLD | GENETIC TOXICITY ASSAYS | POTENCY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | TOXICOLOGY | Neoplasms - metabolism | Mutagens - toxicity | Risk Assessment | Humans | DNA - metabolism | Mutagenicity Tests - methods | DNA - genetics | Neoplasms - chemically induced | Neoplasms - genetics | Models, Genetic | Mutation | Neoplasms - pathology | Mutagenicity Tests - standards | Mutagens - analysis | Benchmarks | Biosafety | Consulting services | Risk assessment | Methods
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4. Full Text Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis
by Smith, Martyn T and Guyton, Kathryn Z and Gibbons, Catherine F and Fritz, Jason M and Portier, Christopher J and Rusyn, Ivan and DeMarini, David M and Caldwell, Jane C and Kavlock, Robert J and Lambert, Paul F and Hecht, Stephen S and Bucher, John R and Stewart, Bernard W and Baan, Robert A and Cogliano, Vincent J and Straif, Kurt
Environmental Health Perspectives, ISSN 0091-6765, 06/2016, Volume 124, Issue 6, pp. 713 - 721
BACKGROUND: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1,... 
EPIGENETIC MECHANISMS | SIGNALING PATHWAYS | BENZENE-INDUCED LEUKEMIA | NUCLEAR RECEPTORS | CANCER HALLMARK | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | LOW-DOSE EXPOSURES | CHEMICAL-MIXTURES | ETHYLENE-OXIDE | TOXICOLOGY | MOLECULAR-MECHANISMS | DRUG-METABOLISM | Risk Assessment - methods | Animals | Polychlorinated Biphenyls - toxicity | Carcinogenicity Tests - methods | Humans | Carcinogenicity Tests - standards | Carcinogens - standards | Benzene - toxicity | Carcinogenesis | Carcinogens - toxicity | Risk Assessment - standards | Monographs | Hydrocarbons | Gene expression | Epidemiology | Chemicals | Data bases | Studies | Carcinogens | Toxicology | Polychlorinated biphenyls--PCB | Tumors | Cancer | Index Medicus | Review
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5. Carcinogenesis and mutagenesis testing
by Douglas, J. F
1984, Contemporary biomedicine, ISBN 9780896030428, xvii, 335
Carcinogens | Mutagens | Carcinogenicity testing | Mutagenicity testing | Mutagenicity tests | methods | analysis
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6. Data book of chromosomal aberration test in vitro
by Ishidate, Motoi
1988, Rev. ed. --, ISBN 9780444809698, 484
Chemical mutagenesis | Carcinogens | Chromosome abnormalities | Mutagens | Handbooks, manuals, etc | Carcinogenicity testing | Mutagenicity testing | Mutagenicity Tests | methods | Chromosome Aberrations | analysis
Book
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7. Full Text Current methods in risk assessment of genotoxic chemicals
by Cartus, Alexander and Schrenk, Dieter
Food and Chemical Toxicology, ISSN 0278-6915, 08/2017, Volume 106, Issue Pt B, pp. 574 - 582
Chemical contaminants and residues are undesired chemicals occurring in consumer products such as food and drugs, at the workplace and in the environment, i.e.... 
Genotoxicity testing | Residues | Carcinogenicity | Contaminants | Risk assessment | Genotoxicity | HEALTH-RISK | DNA-ADDUCTS | SAFETY ASSESSMENT | FOOD SCIENCE & TECHNOLOGY | TOXICITY | ON-A-CHIP | TOXICOLOGICAL CONCERN TTC | SCIENTIFIC OPINION | THRESHOLD | DECISION TREE | TOXICOLOGY | FOOD | Hazard Analysis and Critical Control Points - methods | Risk Assessment - methods | Animals | Food Contamination - analysis | Humans | Mutagenicity Tests - methods | Mutagenicity Tests - standards | Mutagens - analysis | Consumer goods | Dioxin | Food contamination | Methods | Index Medicus
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8. Full Text Refinement, reduction, and replacement of animal toxicity tests by computational methods
by Ford, Kevin A
ILAR Journal, ISSN 1084-2020, 2016, Volume 57, Issue 2, pp. 226 - 233
Widespread public and scientific interest in promoting the care and well-being of animals used for toxicity testing has given rise to improvements in animal... 
3Rs | Drug development | Computational toxicology | QSAR | In silico prediction | Alternative testing method | READ-ACROSS | STRUCTURAL INCLUSION RULES | drug development | IN-SILICO TOOLS | in silico prediction | DECISION-SUPPORT-SYSTEM | PREDICTION | alternative testing method | MODELS | CARCINOGENICITY | SPECIES-DIFFERENCES | VETERINARY SCIENCES | CHEMICAL-SUBSTANCES | computational toxicology | HEPATOTOXICITY | Toxicity Tests - methods | Animal Welfare | Animals | Research | Animal Use Alternatives
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9. Full Text Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses
by Amberg, Alexander and Beilke, Lisa and Bercu, Joel and Bower, Dave and Brigo, Alessandro and Cross, Kevin P and Custer, Laura and Dobo, Krista and Dowdy, Eric and Ford, Kevin A and Glowienke, Susanne and Van Gompel, Jacky and Harvey, James and Hasselgren, Catrin and Honma, Masamitsu and Jolly, Robert and Kemper, Raymond and Kenyon, Michelle and Kruhlak, Naomi and Leavitt, Penny and Miller, Scott and Muster, Wolfgang and Nicolette, John and Plaper, Andreja and Powley, Mark and Quigley, Donald P and Reddy, M. Vijayaraj and Spirkl, Hans-Peter and Stavitskaya, Lidiya and Teasdale, Andrew and Weiner, Sandy and Welch, Dennie S and White, Angela and Wichard, Joerg and Myatt, Glenn J
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 06/2016, Volume 77, pp. 13 - 24
The ICH M7 guideline describes a consistent approach to identify, categorize, and control DNA reactive, mutagenic, impurities in pharmaceutical products to... 
Mutagenic impurities | Impurities | Ames test | Expert review | Toxicity databases | ICH M7 | (Q)SAR | SALMONELLA ASSAY | MEDICINE, LEGAL | CHEMICAL RELATIONAL DATABASES | IN-SILICO SYSTEMS | STRATEGIES | PREDICTION | GENOTOXICITY | CARCINOGENICITY | PHARMACOLOGY & PHARMACY | POTENTIALLY MUTAGENIC IMPURITIES | TOXICOLOGY | EXPERT KNOWLEDGE | Mutagens - chemistry | Guidelines as Topic | Mutagens - toxicity | Toxicology - legislation & jurisprudence | Risk Assessment | Carcinogenicity Tests - methods | Humans | Toxicology - standards | Carcinogenicity Tests - standards | Models, Molecular | Mutagenicity Tests - methods | Animals | Guideline Adherence | Mutagenesis | Computer Simulation | Policy Making | Molecular Structure | DNA Damage | Toxicology - methods | Mutagens - classification | Data Mining - methods | Mutagenicity Tests - standards | Quantitative Structure-Activity Relationship | Databases, Factual | Index Medicus
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10. Full Text Zebrafish: An Emerging Model System for Human Disease and Drug Discovery
by Kari, G and Rodeck, U and Dicker, A P
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2007, Volume 82, Issue 1, pp. 70 - 80
In vivo studies represent an essential step in drug development and currently rely largely on mice, yet limitations of mammalian models motivated the search... 
TRANSGENIC ZEBRAFISH | POTENT INHIBITOR | POSITIONAL CLONING | EMBRYO | SCREEN | ACUTE LYMPHOBLASTIC-LEUKEMIA | GENES | PHARMACOLOGY & PHARMACY | INSERTIONAL MUTAGENESIS | MUTATIONS | CANCER | Drug Evaluation, Preclinical - methods | Mutagens - toxicity | Reproducibility of Results | Embryo, Nonmammalian - pathology | Carcinogenicity Tests - methods | Humans | Gene Expression Regulation, Developmental - drug effects | Antineoplastic Agents - therapeutic use | Mutagenicity Tests - methods | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Zebrafish - genetics | Carcinogens - toxicity | Animals | Neoplasms, Experimental - embryology | Drug Design | Models, Animal | Toxicity Tests - methods | Antineoplastic Agents - pharmacology | Cell Transformation, Neoplastic - drug effects | DNA Damage | Gene Expression Regulation, Neoplastic - drug effects | Neoplasms, Experimental - drug therapy
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