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Journal Article
Cancer Prevention Research, ISSN 1940-6207, 07/2011, Volume 4, Issue 7, pp. 1021 - 1029
Journal Article
Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2008, Volume 68, Issue 16, pp. 6541 - 6549
Journal Article
Genes and Development, ISSN 0890-9369, 06/2006, Volume 20, Issue 12, pp. 1569 - 1574
The tumor suppressor PTEN is frequently inactivated in human cancers. A major downstream effector of PTEN is Akt, which is hyperactivated via PTEN... 
Intestinal polyps | PIN | Endometrium carcinoma | Thyroid and adrenal tumors | Cancer therapy | AKT/PKB | GENETICALLY-ENGINEERED MICE | PTEN | DEVELOPMENTAL BIOLOGY | PHOSPHOINOSITIDE 3-KINASE | CANCER | CELL BIOLOGY | cancer therapy | PATHWAY | thyroid and adrenal tumors | NEOPLASIA | RELEVANCE | intestinal polyps | MUTATION | GENETICS & HEREDITY | endometrium carcinoma | Prostatic Intraepithelial Neoplasia - pathology | Thyroid Neoplasms - enzymology | Proto-Oncogene Proteins c-akt - deficiency | Male | Intestinal Polyps - enzymology | Proto-Oncogene Proteins c-akt - genetics | Adrenal Gland Neoplasms - enzymology | Prostatic Neoplasms - genetics | Endometrial Neoplasms - genetics | Neoplasms - genetics | Female | Pseudolymphoma - genetics | Pseudolymphoma - enzymology | Adrenal Gland Neoplasms - pathology | PTEN Phosphohydrolase - genetics | Prostatic Neoplasms - pathology | Endometrial Neoplasms - enzymology | Neoplasms - enzymology | PTEN Phosphohydrolase - metabolism | Pseudolymphoma - pathology | Thyroid Neoplasms - genetics | Animals | Prostatic Intraepithelial Neoplasia - enzymology | Intestinal Polyps - pathology | Prostatic Neoplasms - enzymology | Endometrial Neoplasms - pathology | Heterozygote | Mice | Prostatic Intraepithelial Neoplasia - genetics | Neoplasms - pathology | Adrenal Gland Neoplasms - genetics | Thyroid Neoplasms - pathology | Index Medicus | Research Communication
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 03/2010, Volume 17, Issue 1, pp. 27 - 37
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2004, Volume 381, Issue 3, pp. 761 - 767
An important regulator involved in oxygen-dependent gene expression is the transcription factor HIF (hypoxia-inducible factor), which is composed of an... 
Post-translational modification | Hypoxia-inducible factor | Protein degradation | Oxygen sensing | Prolyl hydroxylation | Von-Hippel-Lindau protein | TRANSCRIPTIONAL ACTIVITY | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | hypoxia-inducible factor | oxygen sensing | post-translational modification | von-Hippel-Lindau protein | FAMILY | OXYGEN | FACTOR-1-ALPHA | GENE-EXPRESSION | HIF-1-ALPHA | VHL | protein degradation | prolyl hydroxylation | Humans | Half-Life | Kidney Neoplasms - metabolism | Ubiquitin-Protein Ligases - physiology | Bone Neoplasms - pathology | Hypoxia-Inducible Factor 1, alpha Subunit | RNA, Messenger - biosynthesis | Liver Neoplasms - pathology | Liver Neoplasms - enzymology | Kidney Tubules, Proximal - cytology | DNA-Binding Proteins - physiology | Hypoxia - enzymology | Hydroxylation | Hypoxia-Inducible Factor 1 | Immediate-Early Proteins - biosynthesis | Carcinoma, Hepatocellular - enzymology | Tumor Suppressor Proteins - physiology | Epithelial Cells - enzymology | Liver Neoplasms - metabolism | Cell Line, Tumor | Von Hippel-Lindau Tumor Suppressor Protein | Enzyme Induction - physiology | Osteosarcoma - pathology | Carcinoma, Hepatocellular - metabolism | Epithelial Cells - metabolism | Gene Expression Regulation, Enzymologic - physiology | Oxygen - metabolism | Procollagen-Proline Dioxygenase - biosynthesis | Bone Neoplasms - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Kidney Tubules, Proximal - enzymology | Gene Expression Regulation, Neoplastic - physiology | Osteosarcoma - metabolism | Cell Line | Transcription Factors - physiology | Bone Neoplasms - enzymology | Osteosarcoma - enzymology | Adenocarcinoma, Clear Cell - metabolism | Nuclear Proteins - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases | Dioxygenases | Transcription Factors - metabolism | Kidney Neoplasms - enzymology | Carcinoma, Hepatocellular - pathology | Kidney Tubules, Proximal - metabolism | Kidney Neoplasms - pathology | Adenocarcinoma, Clear Cell - pathology | Nuclear Proteins - physiology | Adenocarcinoma, Clear Cell - enzymology | DNA-Binding Proteins - biosynthesis | Index Medicus | ODD, oxygen-dependent degradation domain | aRP, acidic ribosomal protein | RNAi, RNA interference | pVHL, von-Hippel-Lindau protein | EGLN, egg-laying deficient nine-like protein | HIF, hypoxia-inducible factor | siRNA, small interfering RNA | IVTT, in vitro transcription | PHD, prolyl hydroxylase domain containing protein | translation | RT, reverse transcriptase | RPTEC, human renal proximal tubular epithelial cells
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 12/2006, Volume 30, Issue 12, pp. 1502 - 1512
Inflammatory myofibroblastic tumor (IMT) of the urinary tract, also termed postoperative spindle cell nodule, inflammatory pseudotumor, and pseudosarcomatous... 
ALK | Sarcoma | Pseudosarcoma | Bladder | FISH | Urinary tract | Inflammatory myofibroblastic tumor | SURGERY | PSEUDOSARCOMATOUS FIBROMYXOID TUMOR | DIFFERENTIAL-DIAGNOSIS | sarcoma | PLASMA-CELL GRANULOMA | FUSION | ALK EXPRESSION | inflammatory myofibroblastic tumor | urinary tract | PSEUDOTUMOR | PATHOLOGY | LESIONS | ANAPLASTIC LYMPHOMA KINASE | pseudosarcoma | bladder | OF-THE-LITERATURE | Inflammation - pathology | Urologic Diseases - enzymology | Urologic Diseases - genetics | Protein-Tyrosine Kinases - metabolism | Carcinoma, Transitional Cell - enzymology | Humans | Middle Aged | Ureter - enzymology | Child, Preschool | Male | Urinary Bladder - pathology | Urothelium - pathology | Prostate - pathology | Protein-Tyrosine Kinases - genetics | Fibrosarcoma - pathology | Urothelium - enzymology | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Urinary Bladder - enzymology | Child | Carcinoma, Transitional Cell - genetics | Granuloma, Plasma Cell - enzymology | Granuloma, Plasma Cell - genetics | In Situ Hybridization, Fluorescence | Receptor Protein-Tyrosine Kinases | Granuloma, Plasma Cell - pathology | Fibrosarcoma - genetics | Carcinoma, Transitional Cell - pathology | Urologic Diseases - pathology | Adolescent | Aged | Prostate - enzymology | Fibrosarcoma - enzymology | Ureter - pathology | Index Medicus
Journal Article
Histopathology, ISSN 0309-0167, 12/2017, Volume 71, Issue 6, pp. 985 - 988
Journal Article
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 11/2010, Volume 70, Issue 21, pp. 8874 - 8885
Thyroid carcinoma is the most common endocrine malignancy and the first cause of death among endocrine cancers. We show that the tumorigenic capacity in... 
EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | ONCOLOGY | TYROSINE KINASE | ALDEHYDE DEHYDROGENASE-ACTIVITY | GROWTH | RECEPTOR | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | RADIOACTIVE IODINE | CARCINOMA | Proto-Oncogene Proteins c-met - metabolism | Thyroid Neoplasms - enzymology | Cell Proliferation | Adenocarcinoma, Follicular - pathology | Humans | Middle Aged | Male | Thyroid Gland - enzymology | Case-Control Studies | Immunoenzyme Techniques | Young Adult | Flow Cytometry | Lung Neoplasms - secondary | Neoplastic Stem Cells - metabolism | Carcinoma - enzymology | Neoplastic Stem Cells - pathology | Adult | Female | Carcinoma, Papillary - enzymology | Carcinoma - pathology | Proto-Oncogene Proteins c-akt - metabolism | Aldehyde Dehydrogenase - metabolism | Tumor Stem Cell Assay | Lung Neoplasms - enzymology | Neoplasm Invasiveness | RNA, Messenger - genetics | Aldehyde Dehydrogenase - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Papillary - pathology | Cell Adhesion | Adenocarcinoma, Follicular - enzymology | Blotting, Western | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Thyroid Gland - pathology | Fluorescent Antibody Technique | Mice, Inbred NOD | Aged | Mice | Cell Transformation, Neoplastic - pathology | Cell Movement | Thyroid Neoplasms - pathology | Index Medicus
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