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Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 562, Issue 7725, pp. 69 - 75
Primary liver cancer represents a major health problem. It comprises hepatocellular carcinoma (HCC... 
PATHOGENESIS | HEPATOCELLULAR-CARCINOMA | READ ALIGNMENT | HEPATOCYTES | DNA | INFLAMMATION | PACKAGE | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | BINDING | DISCOVERY | Humans | Tumor Microenvironment | Apoptosis - genetics | Hepatocytes - pathology | Male | Gene Expression Profiling | Genes, myc | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | DNA-Binding Proteins - metabolism | Carcinoma, Hepatocellular - genetics | DNA Transposable Elements - genetics | Female | Liver Neoplasms - pathology | Cell Differentiation | Cell Lineage - genetics | Disease Models, Animal | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | Cytokines - metabolism | Liver Neoplasms - genetics | Carcinogenesis - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Transcription Factors - metabolism | Cholangiocarcinoma - pathology | Animals | Epigenesis, Genetic - genetics | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mosaicism | Mice | Necrosis - genetics | Genes, ras | Liver cancer | Research | Carcinogenesis | Oncology, Experimental | Apoptosis | Cancer | Animal models | Cytokines | Liver | Hepatocellular carcinoma | Genomes | Metastasis | Risk analysis | Gene expression | Risk factors | Metastases | Hepatocytes | Morphology | DNA methylation | Tumorigenesis | Bioinformatics | Cholangiocarcinoma | Deoxyribonucleic acid--DNA | Tumors | T-Box Domain Proteins/metabolism | Hepatocytes/pathology | DNA-Binding Proteins/metabolism | Life Sciences | Cholangiocarcinoma/pathology | Transcription Factors/metabolism | Necrosis/genetics | Cytokines/metabolism | Epigenesis, Genetic/genetics | Cyclin-Dependent Kinase Inhibitor p16/deficiency | Carcinoma, Hepatocellular/pathology | DNA Transposable Elements/genetics | Cell Lineage/genetics | T-Box Domain Proteins/genetics | Transcription Factors/genetics | Apoptosis/genetics | Proto-Oncogene Proteins c-akt/genetics | Liver Neoplasms/genetics | Cholangiocarcinoma/genetics | Liver Neoplasms/pathology | DNA-Binding Proteins/genetics | Hepatocytes/metabolism | Carcinoma, Hepatocellular/genetics | Carcinogenesis/genetics
Journal Article
Cancer letters, ISSN 0304-3835, 2016, Volume 383, Issue 1, pp. 18 - 27
Abstract Vascular mimicry (VM) describes the phenomenon that tumor cells but not endothelial cells form vascular-like channels, which provide blood perfusion... 
Hematology, Oncology and Palliative Medicine | TGF-β | Noncoding RNA | SDF1 | CAFs | miR-101 | MIGRATION | VASCULOGENIC MIMICRY | METASTASIS | ANGIOGENESIS | TGF-beta | INVASION | ONCOLOGY | HUMAN-MELANOMA CELLS | EXPRESSION | FUNCTIONAL-SIGNIFICANCE | TUMOR MICROENVIRONMENT | Receptors, Transforming Growth Factor beta - genetics | Cadherins - metabolism | Cancer-Associated Fibroblasts - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Neovascularization, Pathologic | MicroRNAs - metabolism | Antigens, CD - metabolism | Transfection | Time Factors | Cancer-Associated Fibroblasts - transplantation | Carcinoma, Hepatocellular - genetics | Smad2 Protein - genetics | Carcinoma, Hepatocellular - blood supply | Female | Liver Neoplasms - pathology | Tumor Cells, Cultured | Protein-Serine-Threonine Kinases - metabolism | Liver Neoplasms - genetics | Paracrine Communication | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Protein-Serine-Threonine Kinases - genetics | Smad2 Protein - metabolism | Biological Mimicry | Cancer-Associated Fibroblasts - pathology | Animals | Chemokine CXCL12 - metabolism | Liver Neoplasms - blood supply | Receptors, Transforming Growth Factor beta - metabolism | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Mice, Inbred BALB C | MicroRNAs - genetics | Laminin - metabolism | Carcinoma, Hepatocellular - metabolism | Culture Media, Conditioned - metabolism
Journal Article
Journal Article
Cancer letters, ISSN 0304-3835, 2014, Volume 352, Issue 2, pp. 160 - 168
...), a crucial component of immune cells infiltrated in tumor microenvironment, have been found to be associated with progression and metastasis of hepatocellular carcinoma (HCC... 
Hematology, Oncology and Palliative Medicine | Epithelial to mesenchymal transition | Hepatocellular carcinoma | Cancer stem cells | Tumor-associated macrophages | Transforming growth factor-beta1 | MIGRATION | TGF-BETA | METASTASIS | CURATIVE RESECTION | EMT | INVASION | ONCOLOGY | SIGNALING PATHWAY | POLARIZATION | EXPRESSION | PROGRESSION | Carcinoma, Hepatocellular - mortality | Coculture Techniques | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Neoplastic Stem Cells - immunology | Male | Liver Neoplasms - therapy | Liver Neoplasms - mortality | Antigens, CD - metabolism | Epithelial Cell Adhesion Molecule | Young Adult | Neoplastic Stem Cells - metabolism | Time Factors | Epithelial-Mesenchymal Transition | Antigens, Neoplasm - metabolism | Neoplastic Stem Cells - pathology | Adult | Female | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - immunology | Macrophages - immunology | Macrophages - pathology | Paracrine Communication | Signal Transduction | Neoplasm Invasiveness | Kaplan-Meier Estimate | Liver Neoplasms - immunology | Cell Adhesion Molecules - metabolism | Disease-Free Survival | Macrophages - metabolism | Phenotype | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Carcinoma, Hepatocellular - therapy | Mice | Carcinoma, Hepatocellular - metabolism | Cell Movement | Hepatoma | Macrophages | Transforming growth factors | Stem cells | Cancer
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2013, Volume 368, Issue 24, pp. 2266 - 2276
Journal Article
Journal Article
Journal Article