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Journal of the National Cancer Institute, ISSN 0027-8874, 2010, Volume 102, Issue 13, pp. 959 - 971
BACKGROUND: Genome-wide association studies have identified three chromosomal regions at 15q25, 5p15, and 6p21 as being associated with the risk of lung... 
NICOTINE DEPENDENCE | POLYMORPHISMS | ONCOLOGY | PROGNOSTIC MARKER | SEQUENCE VARIANTS | RISK | GENETIC-VARIANTS | SMOKING | DNA-REPAIR | GENOME-WIDE ASSOCIATION | TELOMERE LENGTH | Smoking - adverse effects | Japan - epidemiology | Lung Neoplasms - ethnology | Tobacco Use Disorder - ethnology | United States - epidemiology | Carcinoma, Small Cell - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Carcinoma, Large Cell - ethnology | Case-Control Studies | Carcinoma, Squamous Cell - ethnology | Canada - epidemiology | Carcinoma, Small Cell - ethnology | Lung Neoplasms - etiology | Aged, 80 and over | Adult | Female | Tobacco Use Disorder - genetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Adenocarcinoma - ethnology | Korea - epidemiology | Odds Ratio | Quality Control | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Association Studies | Risk Assessment | Europe | Gene Frequency | Risk Factors | Linkage Disequilibrium - genetics | Genotype | Smoking - genetics | International Cooperation | Chromosomes, Human, Pair 6 | Chromosomes, Human, Pair 5 | Homozygote | Singapore - epidemiology | Chromosomes, Human, Pair 15 | Aged | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Research | Genetic susceptibility | Lung cancer | Risk factors
Journal Article
Lancet Oncology, ISSN 1470-2045, 07/2016, Volume 17, Issue 7, pp. 984 - 993
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 7, pp. 590 - 598
Summary Background Currently, crizotinib is the only drug that has been approved for treatment of ALK -rearranged non-small-cell lung cancer (NSCLC). We aimed... 
Hematology, Oncology and Palliative Medicine | FUSION | GENE | ONCOLOGY | C-MET | KINASE | CRIZOTINIB | ANAPLASTIC LYMPHOMA | INHIBITOR | ROS1 | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Piperidines - pharmacokinetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Lung Neoplasms - genetics | Protein Kinase Inhibitors - pharmacokinetics | Carcinoma, Large Cell - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Adenocarcinoma - drug therapy | Maximum Tolerated Dose | Carcinoma, Squamous Cell - drug therapy | Receptor Protein-Tyrosine Kinases - genetics | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Gene Rearrangement | Carbazoles - pharmacokinetics | Aged | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Care and treatment | Oncology, Experimental | Research | College teachers | Lung cancer, Non-small cell | Drug approval | Cancer
Journal Article
Annals of Surgical Oncology, ISSN 1068-9265, 3/2010, Volume 17, Issue 3, pp. 889 - 897
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e57020
Lung cancer (LC) with its different subtypes is generally known as a therapy resistant cancer with the highest morbidity rate worldwide. Therapy resistance of... 
EPITHELIAL-MESENCHYMAL TRANSITION | TRANSFORMATION | THERAPY | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | GROWTH | HMGA2 | MICE | CARCINOMA | PROGRESSION | TUMOR-INITIATING CELLS | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Cadherins - metabolism | Vimentin - metabolism | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Antigens, CD - genetics | Antigens, CD - metabolism | Octamer Transcription Factor-3 - genetics | Small Cell Lung Carcinoma - metabolism | Adenocarcinoma - metabolism | Neoplastic Stem Cells - metabolism | Vimentin - genetics | Thy-1 Antigens - genetics | Hyaluronan Receptors - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Cadherins - genetics | Lung Neoplasms - genetics | Carcinoma, Large Cell - metabolism | Nanog Homeobox Protein | Immunophenotyping | Small Cell Lung Carcinoma - genetics | Mice, SCID | Hyaluronan Receptors - genetics | Homeodomain Proteins - genetics | Thy-1 Antigens - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Primary Cell Culture | Care and treatment | Analysis | Stem cells | Cancer cells | Physiological aspects | Research | Cancer | Adenocarcinoma | Vimentin | Cell culture | Therapy | Biotechnology | Thoracic surgery | Mesenchyme | Oct-4 protein | Lung cancer | Radiation | Population studies | Identification | Biology | mRNA | Metastasis | Cancer therapies | CD90 antigen | N-Cadherin | Immunology | CD44 antigen | Population | Medical research | Squamous cell carcinoma | Hematology | Small cell lung carcinoma | Cell division | Tumor cell lines | Gene expression | Cadherin | Spheroids | Morbidity | Medicine | Pathology | Lungs | Medical prognosis | Pancreatic cancer | Cell lines | Irradiation | Prostate | Tumors
Journal Article
PLoS Medicine, ISSN 1549-1277, 10/2006, Volume 3, Issue 10, pp. 1865 - 1876
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2008, Volume 14, Issue 20, pp. 6618 - 6624
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2009, Volume 27, Issue 12, pp. 2030 - 2037
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 757 - 765
Purpose: Although large-cell neuroendocrine carcinoma (LCNEC) of the lung shares many clinical characteristics with small-cell lung cancer (SCLC), little is... 
GENE | CISPLATIN | ONCOLOGY | PATHWAY | IMATINIB | MULTICENTER-PHASE-II | DNA-SEQUENCING DATA | CANCER | EXPRESSION | CHEMOTHERAPY | C-KIT PROTEIN | Carcinoma, Small Cell - surgery | Predictive Value of Tests | Adenocarcinoma - pathology | Carcinoma, Small Cell - genetics | Follow-Up Studies | Carcinoma, Large Cell - pathology | Genes, Neoplasm | Humans | Middle Aged | Male | Gene Expression Profiling | Young Adult | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Neoplasm Proteins - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - surgery | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Proteins - biosynthesis | Carcinoma, Neuroendocrine - genetics | Carcinoma, Neuroendocrine - surgery | Exons - genetics | Gene Dosage | Biopsy | Carcinoma, Large Cell - surgery | Carcinoma, Neuroendocrine - pathology | Aged | Mutation | Carcinoma, Small Cell - pathology | Adenocarcinoma - surgery | TOR protein | Profiling | Small cell lung carcinoma | Epidermal growth factor receptors | Exons | p53 Protein | Lung cancer | AKT2 protein | Non-small cell lung carcinoma | AKT protein | Lung carcinoma | ErbB-2 protein | K-Ras protein | 1-Phosphatidylinositol 3-kinase | Gene sequencing | Alterations | Experimental design | Coding | Fibroblast growth factor receptor 1 | PTEN protein | Tumors | Cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2008, Volume 26, Issue 15, pp. 2442 - 2449
Purpose Somatic mutations in the epidermal growth factor receptor (EGFR) correlate with increased response in patients with non-small-cell lung cancer (NSCLC)... 
GENE-MUTATIONS | PHASE-II TRIAL | ONCOLOGY-GROUP | GROWTH-FACTOR-RECEPTOR | ONCOLOGY | ADENOCARCI