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Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 1, pp. 42 - 51
Journal Article
European Respiratory Journal, ISSN 0903-1936, 12/2015, Volume 46, Issue 6, pp. 1762 - 1772
The impact of host immunity on outcome in nonsmall cell lung cancer (NSCLC) is controversial. We examined the relationship between lymphoid infiltration... 
SURVIVAL | TERTIARY LYMPHOID STRUCTURES | IMMUNE CELLS | GASTRIC-CANCER | RESPIRATORY SYSTEM | RATIO | CERVICAL-CANCER | RECURRENCE | OVARIAN-CANCER | ADVERSE PROGNOSIS | CARCINOMA | Immunohistochemistry | Multivariate Analysis | Receptor, Epidermal Growth Factor - genetics | T-Lymphocytes, Regulatory - metabolism | Adenocarcinoma - pathology | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Lung Neoplasms - pathology | Male | Pneumonectomy | T-Lymphocytes, Regulatory - immunology | Neoplasm, Residual | Carcinoma, Large Cell - immunology | Forkhead Transcription Factors - metabolism | Aged, 80 and over | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - surgery | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Proportional Hazards Models | Tumor Burden | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Algorithms | Image Processing, Computer-Assisted | Carcinoma, Large Cell - surgery | Lymphocyte Count | Lung Neoplasms - surgery | Aged | CD8-Positive T-Lymphocytes - immunology | Neoplasm Staging | Adenocarcinoma - surgery | Cohort Studies
Journal Article
Journal Article
Clinical Lung Cancer, ISSN 1525-7304, 2016, Volume 18, Issue 2, pp. 220 - 233.e8
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 2017, Volume 16, Issue 1, pp. 3 - 13
Lung cancer has the highest mortality rate among cancer patients in the world, in particular because most patients are only diagnosed at an advanced and... 
lung cancer | computed tomography (CT) screening | antibody | tumor immunology | proteomics | next-generation sequencing (NGS) | antigen | early detection | biomarker | SCREENING TRIAL | PULMONARY NODULES | BIOCHEMICAL RESEARCH METHODS | DANTE TRIAL | IMMUNOGLOBULIN PEPTIDES | NELSON TRIAL | HIGH-RISK | SPIRAL COMPUTED-TOMOGRAPHY | ANTIBODY REPERTOIRE | DOSE CT | CELL | Carcinoma, Squamous Cell - blood | Early Detection of Cancer - methods | Autoantibodies - blood | Carcinoma, Squamous Cell - genetics | Humans | Tomography, X-Ray Computed | Carcinoma, Squamous Cell - diagnostic imaging | Small Cell Lung Carcinoma - blood | Carcinoma, Large Cell - immunology | Antigens, Neoplasm - blood | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Carcinoma, Large Cell - blood | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Gene Expression | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - blood | Adenocarcinoma - immunology | Small Cell Lung Carcinoma - genetics | Carcinoma, Squamous Cell - immunology | Biomarkers, Tumor - blood | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Carcinoma, Large Cell - diagnostic imaging | Small Cell Lung Carcinoma - diagnostic imaging | Carcinoma, Non-Small-Cell Lung - blood | Lung Neoplasms - diagnostic imaging | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Lung Neoplasms - blood | Adenocarcinoma - diagnostic imaging | Autoantibodies - genetics | Biomarkers, Tumor - immunology | Small Cell Lung Carcinoma - immunology
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2012, Volume 131, Issue 5, pp. E649 - E658
The spontaneous immune responses against XAGE‐1b (GAGED2a) were analyzed in non‐small cell lung cancer (NSCLC) patients. An antibody response against XAGE‐1b... 
XAGE‐1b (GAGED2a) | antibody and T‐cell responses | cancer/testis antigen | cancer vaccine | non‐small cell lung cancer | Antibody and T-cell responses | Cancer vaccine | Cancer/testis antigen | XAGE-1b (GAGED2a) | Non-small cell lung cancer | non-small cell lung cancer | IMMUNE-RESPONSE | IDENTIFICATION | testis antigen | antibody and T-cell responses | PEPTIDE | FAMILY | ONCOLOGY | CANCER/TESTIS ANTIGENS | GENES | cancer | TESTIS ANTIGEN NY-ESO-1 | EXPRESSION | CD8-Positive T-Lymphocytes - pathology | Cell Proliferation | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Dendritic Cells - immunology | Humans | Lung Neoplasms - metabolism | Dendritic Cells - pathology | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - pathology | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | Adenocarcinoma - metabolism | Carcinoma, Large Cell - immunology | Peptide Fragments - immunology | Antigens, Neoplasm - metabolism | CD8-Positive T-Lymphocytes - metabolism | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Lung - metabolism | Epitopes, T-Lymphocyte - immunology | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Dendritic Cells - metabolism | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Antibodies, Neoplasm - immunology | Carcinoma, Large Cell - metabolism | Enzyme-Linked Immunosorbent Assay | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Antibodies, Neoplasm - blood | RNA, Messenger - genetics | CD4-Positive T-Lymphocytes - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Squamous Cell - immunology | Blotting, Western | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Neoplasm Staging | Epitopes, T-Lymphocyte - metabolism | Lung - immunology | Apoptosis | Immunoglobulins | Chemotherapy | T cell receptors | Vaccines | Peptides | Lung cancer | Adenocarcinoma
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2012, Volume 49, Issue 4, pp. 852 - 859
Abstract Purpose Dendritic cell (DC)-based vaccines have been expected to serve as new therapeutic approaches for advanced non-small cell lung cancers... 
Hematology, Oncology and Palliative Medicine | Wilms’ tumour-1 | Dendritic cell vaccine | Overall survival | Non-small cell lung cancer | Wilms' tumour-1 | PHASE-III | COMBINATION | GEMCITABINE | CHEMOTHERAPY | PACLITAXEL | TRIAL | TOLL-LIKE RECEPTOR-4 | CISPLATIN | ONCOLOGY | IMMUNOTHERAPY | WT1 | Prognosis | Follow-Up Studies | Lung Neoplasms - mortality | Dendritic Cells - immunology | Humans | Middle Aged | Male | Carcinoma, Large Cell - mortality | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - immunology | Cancer Vaccines - therapeutic use | Carcinoma, Squamous Cell - mortality | Carcinoma, Large Cell - immunology | Peptide Fragments - immunology | WT1 Proteins - immunology | Aged, 80 and over | Adult | Female | Retrospective Studies | T-Lymphocytes, Cytotoxic - immunology | Adenocarcinoma - immunology | Neoplasm Recurrence, Local - therapy | Carcinoma, Squamous Cell - therapy | Survival Rate | Lung Neoplasms - therapy | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Carcinoma, Non-Small-Cell Lung - therapy | Lung Neoplasms - immunology | Adenocarcinoma - therapy | Aged | Neoplasm Staging | Dendritic Cells - transplantation | Carcinoma, Large Cell - therapy | Adenocarcinoma - mortality | Cancer vaccines | Antigens | Medical colleges | Care and treatment | Peptides | Dendritic cells | Patient outcomes | Lung cancer, Non-small cell | Tumor proteins | Tumors | Cancer
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 825 - 832
Purpose: Immunotherapy with antibodies against B7/CD28 family members, including PD-1, PD-L1, and CTLA-4 has shifted the treatment paradigm for non-small cell... 
SURVIVAL | ACTIVATION | THERAPY | ONCOLOGY | MOLECULE | PD-L1 | B7-H3 | IDENTIFICATION | CELL | Tissue Array Analysis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Molecular Targeted Therapy | Adenocarcinoma - metabolism | Carcinoma, Large Cell - immunology | Immunotherapy | Female | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Retrospective Studies | Lung Neoplasms - genetics | Carcinoma, Large Cell - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Carcinoma, Non-Small-Cell Lung - metabolism | Immunoglobulins - analysis | Lymphatic Metastasis | Continental Population Groups - genetics | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Genes, erbB-1 | Lung Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - pathology | Neoplasm Proteins - analysis | Aged | Mutation | Adenocarcinoma | Small cell lung carcinoma | Epidermal growth factor receptors | PD-1 protein | Lung cancer | Antibodies | Non-small cell lung carcinoma | Lymphocytes T | Histology | Lung carcinoma | Multivariate analysis | Tissues | CD28 antigen | B7 antigen | CTLA-4 protein | Immune checkpoint | Experimental design | PD-L1 protein | Tumors | Cancer | HHLA2 | immune checkpoint
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2008, Volume 26, Issue 9, pp. 1452 - 1458
Journal Article
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 05/2015, Volume 68, Issue 5, pp. 368 - 373
Objective Despite advances in therapy, lung cancer is still the leading cause of cancer-related mortality in the world. Further prognostic tools are warranted... 
BIOMARKER | PERSPECTIVES | CARCINOMAS | RESISTANCE | RECURRENCE | CD44V6 | PATHOLOGY | VARIANT | Immunohistochemistry | Multivariate Analysis | Predictive Value of Tests | Lung Neoplasms - mortality | Tissue Array Analysis | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Carcinoma, Large Cell - mortality | Extracellular Matrix Proteins - analysis | Young Adult | Carcinoma, Large Cell - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Time Factors | Carcinoma, Large Cell - immunology | Aged, 80 and over | Adult | Female | Carcinoma, Non-Small-Cell Lung - surgery | Biomarkers, Tumor - analysis | Adenocarcinoma - immunology | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Lymphatic Metastasis | Chi-Square Distribution | Carcinoma, Non-Small-Cell Lung - mortality | Adenocarcinoma - secondary | Carcinoma, Non-Small-Cell Lung - immunology | Hyaluronan Receptors - analysis | Lung Neoplasms - immunology | Carcinoma, Large Cell - surgery | Lung Neoplasms - surgery | Aged | Neoplasm Staging | Adenocarcinoma - mortality | Adenocarcinoma - surgery | Usage | Prognosis | Lung cancer | Therapeutics | Research | Gene expression | Hyaluronic acid | Homeopathy | Materia medica and therapeutics | Immunoglobulins | Statistical analysis | Motility | Mortality | Metastasis | Kinases | Cancer therapies | Proteins | Chemotherapy | Acids | Medical prognosis | Apoptosis
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 6/2009, Volume 58, Issue 6, pp. 967 - 976
HM1.24 antigen (CD317) was originally identified as a cell surface protein that is preferentially overexpressed on multiple myeloma cells. Immunotherapy using... 
Biomedicine | Immunology | Lung cancer | Immunotherapy | Cancer Research | Oncology | Interferon | Antibody-dependent cellular cytotoxicity | HM1.24 antigen | MULTIPLE-MYELOMA | CELLS | MONOCLONAL-ANTIBODY | ANTIGENS | IMMUNOLOGY | IDENTIFICATION | ONCOLOGY | GENES | MOLECULAR-CLONING | MULTIDRUG-RESISTANCE | EXPRESSION | CARCINOMA | Antigens, CD - immunology | Cell Proliferation | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | GPI-Linked Proteins | Antibody-Dependent Cell Cytotoxicity - immunology | Immunoenzyme Techniques | Pleural Effusion, Malignant - therapy | Adenocarcinoma - metabolism | Flow Cytometry | Membrane Glycoproteins - antagonists & inhibitors | Carcinoma, Large Cell - immunology | Female | Membrane Glycoproteins - immunology | Tumor Cells, Cultured | Carcinoma, Large Cell - metabolism | Pleural Effusion, Malignant - metabolism | Carcinoma, Small Cell - metabolism | Adenocarcinoma - immunology | Carcinoma, Squamous Cell - therapy | Lung Neoplasms - therapy | Mice, SCID | Carcinoma, Squamous Cell - immunology | Pleural Effusion, Malignant - immunology | Carcinoma, Small Cell - immunology | Carcinoma, Small Cell - therapy | Lung Neoplasms - immunology | Animals | Adenocarcinoma - therapy | Fluorescent Antibody Technique | Mice | Antibody-Dependent Cell Cytotoxicity - drug effects | Carcinoma, Large Cell - therapy | Immunohistochemistry | Care and treatment | Biological products | Corticosteroids | Oncology, Experimental | Multiple myeloma | Respiratory agents | Research | Lung cancer, Non-small cell | Immunity | Pharmacy | Interferon beta | Universities and colleges | Drug therapy | Tumors | Cancer
Journal Article