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Cancer Cell, ISSN 1535-6108, 02/2013, Volume 23, Issue 2, pp. 249 - 262
Journal Article
Plos One, ISSN 1932-6203, 2013, Volume 8, Issue 4, pp. e61895 - e61895
Several chemotherapeutics exert immunomodulatory effects. One of these is the nucleoside analogue gemcitabine, which is widely used in patients with lung... 
T-CELL RESPONSES | TUMOR-BEARING MICE | COMBINATION | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | Mesothelioma - immunology | Lung Neoplasms - drug therapy | Neoplasm Transplantation | CD8-Positive T-Lymphocytes - pathology | Mesothelioma - pathology | Lung Neoplasms - mortality | Carcinoma, Lewis Lung - immunology | Deoxycytidine - pharmacology | Lung Neoplasms - pathology | Mesothelioma - mortality | Lymphocyte Depletion | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Drug Therapy, Combination | Immunity, Innate - drug effects | Antibodies, Monoclonal - pharmacology | Mice, Transgenic | Carcinoma, Lewis Lung - drug therapy | Mesothelioma - drug therapy | Drug Synergism | Lung Neoplasms - immunology | Animals | Tumor Burden - drug effects | Carcinoma, Lewis Lung - mortality | CD8-Positive T-Lymphocytes - drug effects | Survival Analysis | Carcinoma, Lewis Lung - pathology | Mice | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | Deoxycytidine - analogs & derivatives | Immunologic Factors - pharmacology | Antimitotic agents | Viral antibodies | Chemotherapy | Analysis | Lung cancer | Melanoma | Antibodies | Antineoplastic agents | T cells | Drug approval | Cancer | Ovarian cancer | Drugs | Animal models | Asbestos | Gemcitabine | Ovarian carcinoma | CD8 antigen | Blocking antibodies | Clinical trials | Cytotoxicity | Mesothelioma | Oncology | Lymphocytes T | Metastasis | Immunity | Cancer therapies | Immunosuppressive agents | Metastases | Ethics | CTLA-4 protein | Immunology | Lymphocytes | Immunotherapy | Drug dosages | Immune system | Medical research | Antigens | Immune response | Immunomodulation | T cell receptors | Breast cancer | Pharmacology | Patients | CD4 antigen | Medicine | Hospitals | Immune checkpoint | Immunogenicity | Synergistic effect | Nucleoside analogs | Apoptosis
Journal Article
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 17, pp. 3479 - 3491
Journal Article
Cancer Cell, ISSN 1535-6108, 01/2015, Volume 27, Issue 1, pp. 123 - 137
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 3, pp. 263 - 273
Several hypotheses have been proposed to explain how antiangiogenic drugs enhance the treatment efficacy of cytotoxic chemotherapy, including impairing the... 
CELLCYCLE | BREAST-CANCER | LUNG-CANCER | RECRUITMENT | THERAPY | ONCOLOGY | VEGF | CHEMOKINE | GROWTH-FACTOR | TUMOR ANGIOGENESIS | NEOVASCULARIZATION | METRONOMIC CHEMOTHERAPY | CELL BIOLOGY | Paclitaxel - pharmacology | Apoptosis - drug effects | Humans | Melanoma, Experimental - drug therapy | Antibodies, Monoclonal - therapeutic use | Deoxycytidine - pharmacology | Antineoplastic Agents - therapeutic use | Deoxycytidine - therapeutic use | Neoplasms - blood | Angiogenesis Inhibitors - therapeutic use | Bone Marrow Cells - drug effects | Female | Antineoplastic Agents - pharmacology | Drug Therapy, Combination | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Vascular Endothelial Growth Factor A - blood | Angiogenesis Inhibitors - pharmacology | Melanoma, Experimental - pathology | Carcinoma, Lewis Lung - blood | Breast Neoplasms - drug therapy | Paclitaxel - therapeutic use | Carcinoma, Lewis Lung - drug therapy | Neoplasms - drug therapy | Animals | Tumor Burden - drug effects | Breast Neoplasms - pathology | Chemokine CXCL12 - blood | Breast Neoplasms - blood | Carcinoma, Lewis Lung - pathology | Stem Cells - drug effects | Stem Cells - pathology | Cell Proliferation - drug effects | Melanoma, Experimental - blood | Mice | Mice, Inbred BALB C | Endothelial Cells - pathology | Neoplasms - pathology | Deoxycytidine - analogs & derivatives | Endothelial Cells - drug effects | Antimitotic agents | Chemotherapy | Antineoplastic agents | Antitank weapons | Cancer | Tumors | Endothelium
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, p. 14293
Involvement of the immune system in tumour progression is at the forefront of cancer research. Analysis of the tumour immune microenvironment has yielded a... 
NANOPARTICLES | IMMUNE CELLS | INHIBITION | MULTIDISCIPLINARY SCIENCES | KINASE | DYNAMICS | TUMOR-ASSOCIATED MACROPHAGES | MYELOID CELLS | BLOCKADE | POLARIZATION | PROBES
Journal Article
Blood, ISSN 0006-4971, 02/2010, Volume 115, Issue 7, pp. 1461 - 1471
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2016, Volume 30, Issue 6, pp. 953 - 967
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 05/2015, Volume 205, pp. 89 - 97
Platinum-based polymeric nano-drugs, especially cisplatin-loaded polymeric nanoparticles (CDDP-NPs), have been extensively exploited for the treatment of solid... 
Glutamic acid | Pharmacokinetics | Nanoparticle | Biodistribution | Cisplatin | SOLID TUMORS | DRUG-DELIVERY | ANTICANCER DRUG | CANCER | CHEMISTRY, MULTIDISCIPLINARY | ENHANCED PERMEABILITY | CO-DELIVERY | INCORPORATED POLYMERIC MICELLES | PLGA-MPEG NANOPARTICLES | PHARMACOLOGY & PHARMACY | ANTITUMOR EFFICACY | TARGETED DELIVERY | Injections, Intravenous | Molecular Weight | Cisplatin - pharmacokinetics | Area Under Curve | Colonic Neoplasms - drug therapy | Male | Metabolic Clearance Rate | Polyethylene Glycols - chemistry | Antineoplastic Agents - administration & dosage | Colonic Neoplasms - metabolism | Cisplatin - administration & dosage | Drug Carriers | Nanoparticles | Polyglutamic Acid - analogs & derivatives | Tissue Distribution | Cisplatin - chemistry | Cisplatin - blood | Female | Antineoplastic Agents - pharmacokinetics | Nanomedicine | Mice, Inbred C57BL | Technology, Pharmaceutical - methods | Antineoplastic Agents - chemistry | Carcinoma, Lewis Lung - metabolism | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Carcinoma, Lewis Lung - drug therapy | Particle Size | Polyglutamic Acid - chemistry | Animals | Tumor Burden - drug effects | Colonic Neoplasms - pathology | Antineoplastic Agents - blood | Carcinoma, Lewis Lung - pathology | Mice | Mice, Inbred BALB C | Antimitotic agents | Ethylene glycol | Chemical plants | Analysis | Amino acids | Glutamate | Antineoplastic agents | Tumors
Journal Article
Journal Article