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Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 12, pp. 1475 - 1481
...). We integrated metabolic tracing and transcriptional profiling of a large panel of non-small cell lung cancer (NSCLC... 
ACTIVATION | PROTEIN | GLUTAMINE | PATHWAY | GLUCOSE | GROWTH | GENETICS & HEREDITY | GENE-EXPRESSION | IMPAIR | CARCINOMA | KEAP1 MUTATIONS | RNA, Small Interfering - genetics | NF-E2-Related Factor 2 - antagonists & inhibitors | Cell Proliferation | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Serine - biosynthesis | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Carcinoma, Non-Small-Cell Lung - secondary | Biomarkers, Tumor - metabolism | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Non-Small-Cell Lung - mortality | Adenocarcinoma - secondary | Blotting, Western | Xenograft Model Antitumor Assays | Animals | NF-E2-Related Factor 2 - metabolism | Biomarkers, Tumor - genetics | Mice | Adenocarcinoma - mortality | Apoptosis | Transcription factors | Cell metabolism | Development and progression | Genetic aspects | Genetic transcription | Lung cancer, Non-small cell | Properties | Health aspects | Medical research | Enzymes | Lung cancer | Biosynthesis | RNA polymerase | Metabolism | Gene expression | Experiments | Metabolites | Scientific imaging | Tumorigenesis | Labeling | Bioinformatics | Mass spectrometry
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 21, pp. 2018 - 2028
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 371, Issue 1, pp. 99 - 106
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2019, Volume 381, Issue 21, pp. 2020 - 2031
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 2016, Volume 11, Issue 1, pp. 62 - 71
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2017, Volume 376, Issue 25, pp. 2415 - 2426
Journal Article
The lancet oncology, ISSN 1470-2045, 2013, Volume 14, Issue 7, pp. 590 - 598
Summary Background Currently, crizotinib is the only drug that has been approved for treatment of ALK -rearranged non-small-cell lung cancer (NSCLC... 
Hematology, Oncology and Palliative Medicine | FUSION | GENE | ONCOLOGY | C-MET | KINASE | CRIZOTINIB | ANAPLASTIC LYMPHOMA | INHIBITOR | ROS1 | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Piperidines - pharmacokinetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Lung Neoplasms - genetics | Protein Kinase Inhibitors - pharmacokinetics | Carcinoma, Large Cell - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Adenocarcinoma - drug therapy | Maximum Tolerated Dose | Carcinoma, Squamous Cell - drug therapy | Receptor Protein-Tyrosine Kinases - genetics | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Gene Rearrangement | Carbazoles - pharmacokinetics | Aged | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Care and treatment | Oncology, Experimental | Research | College teachers | Lung cancer, Non-small cell | Drug approval | Cancer
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 3, p. e60317
.... However, its role in non-small cell lung cancer (NSCLC) has not been elucidated. The aim of this study was to investigate the contribution of miR-146a to various aspects of the malignant phenotype of human NSCLCs... 
SUPPRESSOR | ONCOGENESIS | RNA | MULTIDISCIPLINARY SCIENCES | CERVICAL-CANCER | INTERFERENCE | MICRORNAS | NF-KAPPA-B | FACTOR RECEPTOR | EXPRESSION | CONTRIBUTES | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Middle Aged | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | NF-kappa B - metabolism | Antibodies, Monoclonal, Humanized - pharmacology | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacology | Lung - metabolism | Cetuximab | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | ErbB Receptors - metabolism | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Lung - drug effects | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | MicroRNAs - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Apoptosis | Cell Movement | MicroRNA | Growth | Monoclonal antibodies | Lung cancer, Small cell | Development and progression | Lung cancer, Non-small cell | Health aspects | Cell proliferation | Laboratories | Lung cancer | Oncology | Drug delivery | Kinases | Paraffin | Cancer therapies | Metastases | Signal transduction | Cell growth | miRNA | Inhibition | Gefitinib | Sensitizing | NF-κB protein | Phenotypes | Cytokines | Epidermal growth factor receptors | Non-small cell lung carcinoma | siRNA | Breast cancer | Gene expression | Ribonucleic acid--RNA | Patients | Pathology | Signaling | Chemotherapy | Thyroid cancer | MicroRNAs | Medical prognosis | Pancreatic cancer | Biomarkers | Mutation | Cell migration | Cervical cancer | Tumors | Cancer | Ribonucleic acid
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2013, Volume 368, Issue 12, pp. 1101 - 1110
.... In patients with resected stage IB, IIA or IIB, or IIIA non–small-cell lung cancer (NSCLC), platinum-based postoperative chemotherapy is now standard treatment, with an estimated increase in the survival rate of 4 to 5% at 5 years... 
SURVIVAL | TRIAL | MEDICINE, GENERAL & INTERNAL | RRM1 | COMPLEMENTATION GROUP 1 | MESSENGER-RNA EXPRESSION | VALIDATION | MONOCLONAL-ANTIBODIES | III BETA-TUBULIN | CHEMOTHERAPY | Epitope Mapping | Lung Neoplasms - drug therapy | Endonucleases - genetics | Lung Neoplasms - mortality | Humans | Immunoglobulin G | Antineoplastic Agents - therapeutic use | Endonucleases - metabolism | DNA-Binding Proteins - metabolism | Protein Isoforms - metabolism | DNA, Neoplasm | Biomarkers, Tumor - metabolism | Chemotherapy, Adjuvant | Lung Neoplasms - genetics | DNA-Binding Proteins - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Kaplan-Meier Estimate | Endonucleases - immunology | Epitopes | DNA-Binding Proteins - genetics | Carcinoma, Non-Small-Cell Lung - mortality | Drug Resistance, Neoplasm - genetics | Cisplatin - therapeutic use | DNA Repair | Carcinoma, Non-Small-Cell Lung - drug therapy | Protein Isoforms - genetics | Usage | Diagnostic immunohistochemistry | Causes of | Genetic aspects | Research | Diagnosis | Gene expression | Lung cancer, Non-small cell | DNA repair | Care and treatment | Lung cancer, Small cell | Health aspects | Cisplatin | Decision making | Lung cancer | DNA damage | Discordance | Clinical trials | Antibodies | Non-small cell lung carcinoma | Nucleotide excision repair | Proteins | Chemotherapy | Lungs | Platinum | Isoforms | Biomarkers | ERCC1 protein | Deoxyribonucleic acid--DNA | Tumors
Journal Article
Journal Article