X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (9608) 9608
female (4981) 4981
oncology (4639) 4639
cancer (4481) 4481
male (3855) 3855
middle aged (3543) 3543
animals (3420) 3420
pancreatic neoplasms - pathology (3253) 3253
pancreatic cancer (3057) 3057
aged (3023) 3023
cell line, tumor (2958) 2958
pancreatic neoplasms - metabolism (2857) 2857
expression (2652) 2652
prognosis (2642) 2642
tumors (2550) 2550
metastasis (2516) 2516
carcinoma (2504) 2504
immunohistochemistry (2471) 2471
adult (2259) 2259
carcinoma, pancreatic ductal - pathology (2253) 2253
mice (2129) 2129
carcinoma, pancreatic ductal - metabolism (2103) 2103
gene expression (1926) 1926
gene expression regulation, neoplastic (1888) 1888
pancreatic neoplasms - genetics (1794) 1794
proteins (1782) 1782
adenocarcinoma (1754) 1754
cell biology (1747) 1747
pathology (1601) 1601
research (1595) 1595
apoptosis (1557) 1557
biomarkers, tumor - metabolism (1426) 1426
carcinoma, pancreatic ductal - genetics (1402) 1402
aged, 80 and over (1397) 1397
analysis (1372) 1372
cell proliferation (1368) 1368
breast cancer (1321) 1321
signal transduction (1317) 1317
development and progression (1277) 1277
survival (1240) 1240
medical prognosis (1195) 1195
genetic aspects (1171) 1171
breast-cancer (1091) 1091
gastroenterology & hepatology (1076) 1076
biochemistry & molecular biology (1053) 1053
surgery (1050) 1050
pancreas (1036) 1036
chemotherapy (1019) 1019
health aspects (1019) 1019
growth (995) 995
neoplasm invasiveness (977) 977
research article (959) 959
neoplasm staging (923) 923
cells (901) 901
kinases (896) 896
care and treatment (895) 895
medicine (864) 864
mutation (859) 859
medicine & public health (833) 833
pancreatic neoplasms - drug therapy (832) 832
multidisciplinary sciences (831) 831
metastases (821) 821
disease progression (818) 818
progression (804) 804
biomarkers (803) 803
hepatocellular-carcinoma (793) 793
adenocarcinoma - pathology (789) 789
diagnosis (787) 787
cancer therapies (771) 771
mice, nude (767) 767
cancer research (758) 758
activation (750) 750
invasion (733) 733
adenocarcinoma - metabolism (730) 730
breast neoplasms - pathology (724) 724
studies (715) 715
biomarkers, tumor - genetics (705) 705
gene-expression (701) 701
pancreatic ductal adenocarcinoma (701) 701
ductal adenocarcinoma (695) 695
up-regulation (693) 693
proliferation (688) 688
breast neoplasms - metabolism (680) 680
epithelial-mesenchymal transition (669) 669
cell growth (666) 666
stem cells (656) 656
genes (641) 641
angiogenesis (637) 637
reverse transcriptase polymerase chain reaction (634) 634
physiological aspects (629) 629
down-regulation (628) 628
medicine, research & experimental (628) 628
science (627) 627
biology (625) 625
carcinoma, pancreatic ductal - drug therapy (625) 625
cell cycle (623) 623
tumor cells, cultured (615) 615
patients (607) 607
kaplan-meier estimate (598) 598
survival analysis (597) 597
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (10996) 10996
Chinese (42) 42
Japanese (31) 31
Norwegian (6) 6
German (5) 5
Portuguese (4) 4
Russian (4) 4
Czech (2) 2
French (2) 2
Korean (2) 2
Hungarian (1) 1
Polish (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


by Raphael, Benjamin J and Hruban, Ralph H and Aguirre, Andrew J and Moffitt, Richard A and Yeh, Jen Jen and Stewart, Chip and Robertson, A. Gordon and Cherniack, Andrew D and Gupta, Manaswi and Getz, Gad and Gabriel, Stacey B and Meyerson, Matthew and Cibulskis, Carrie and Fei, Suzanne S and Hinoue, Toshinori and Shen, Hui and Laird, Peter W and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Akbani, Rehan and Loher, Phillipe and Londin, Eric R and Rigoutsos, Isidore and Telonis, Aristeidis G and Gibb, Ewan A and Goldenberg, Anna and Mezlini, Aziz M and Hoadley, Katherine A and Collisson, Eric and Lander, Eric and Murray, Bradley A and Hess, Julian and Rosenberg, Mara and Bergelson, Louis and Zhang, Hailei and Cho, Juok and Tiao, Grace and Kim, Jaegil and Livitz, Dimitri and Leshchiner, Ignaty and Reardon, Brendan and Van Allen, Eliezer and Kamburov, Atanas and Beroukhim, Rameen and Saksena, Gordon and Schumacher, Steven E and Noble, Michael S and Heiman, David I and Gehlenborg, Nils and Lawrence, Michael S and Adsay, Volkan and Petersen, Gloria and Klimstra, David and Bardeesy, Nabeel and Leiserson, Mark D.M and Bowlby, Reanne and Kasaian, Katayoon and Birol, Inanc and Mungall, Karen L and Sadeghi, Sara and Weinstein, John N and Spellman, Paul T and Liu, Yuexin and Amundadottir, Laufey T and Tepper, Joel and Singhi, Aatur D and Dhir, Rajiv and Paul, Drwiega and Smyrk, Thomas and Zhang, Lizhi and Kim, Paula and Bowen, Jay and Frick, Jessica and Gastier-Foster, Julie M and Gerken, Mark and Lau, Kevin and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Renkel, Jeremy and Sherman, Mark and Wise, Lisa and Yena, Peggy and Zmuda, Erik and Shih, Juliann and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chu, Andy and Chuah, Eric and Clarke, Amanda and Dhalla, Noreen and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network. Electronic address: andrew_aguirre@dfci.harvard.edu and Cancer Genome Atlas Research Network
Cancer cell, ISSN 1535-6108, 2017, Volume 32, Issue 2, pp. 185 - 203.e13
Journal Article
Oncogene, ISSN 1476-5594, 2016, Volume 36, Issue 9, pp. 1232 - 1244
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a high degree of inflammation and profound immune suppression... 
COLONY-STIMULATING FACTOR | TUMOR PROGRESSION | ONCOGENIC KRAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | PROMOTES RESISTANCE | CELL BIOLOGY | LUNG-CANCER | ONCOLOGY | GM-CSF | GENETICS & HEREDITY | SUPPRESSOR-CELLS | TRANSGENIC MICE | PHASE-2 TRIAL | Inflammation - pathology | Adenocarcinoma - pathology | Cell Proliferation | Pancreatic Neoplasms - metabolism | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Phosphoproteins - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | T-Lymphocytes - metabolism | Biomarkers, Tumor - metabolism | Pancreatitis - immunology | Cell Differentiation | Phosphoproteins - physiology | T-Lymphocytes - pathology | Tumor Cells, Cultured | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Myeloid-Derived Suppressor Cells - metabolism | Myeloid-Derived Suppressor Cells - pathology | Acute Disease | Myeloid-Derived Suppressor Cells - immunology | Cytokines - metabolism | Macrophages - pathology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Survival Rate | Inflammation - immunology | Phosphoproteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Xenograft Model Antitumor Assays | Adaptor Proteins, Signal Transducing - physiology | Macrophages - metabolism | Animals | Pancreatic Neoplasms - immunology | Adaptor Proteins, Signal Transducing - genetics | Pancreatitis - pathology | T-Lymphocytes - immunology | Mice | Pancreatitis - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Neoplasm Staging | Apoptosis | Proteins | Inflammation | Cytokines | Pancreatic cancer | PDAC | MDSC | inflammation | acute pancreatitis | YAP | T cells | Macrophages
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 31, pp. 12649 - 12654
.... Ubiquitin E3 ligase ring finger 43 (RNF43) has been suggested as a negative regulator of Wnt signaling, and mutations of RNF43 have been identified in various tumors, including cystic pancreatic tumors... 
Adenocarcinoma | Acinar cells | Cell growth | Cell lines | Pancreatic cells | Small interfering RNA | Genetic mutation | Pancreatic neoplasms | Tumors | Cancer | INHIBITION | PATHWAY | STABILIZATION | REGENERATION | MULTIDISCIPLINARY SCIENCES | DISEASE | GROWTH | ACINAR-CELLS | BETA-CATENIN | INTRAEPITHELIAL NEOPLASIA | CANCER | Oncogene Proteins - genetics | Pancreatic Neoplasms - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Wnt Proteins - metabolism | Carcinoma, Pancreatic Ductal - genetics | DNA-Binding Proteins - metabolism | Pancreatic Neoplasms - drug therapy | Wnt Proteins - genetics | HEK293 Cells | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Wnt Signaling Pathway | Acyltransferases | beta Catenin | Membrane Proteins - genetics | Oncogene Proteins - metabolism | Frizzled Receptors - metabolism | Pancreatic Neoplasms - genetics | DNA-Binding Proteins - genetics | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - drug therapy | Frizzled Receptors - genetics | Membrane Proteins - antagonists & inhibitors | Cell Line, Tumor | Mutation | Clinical Trials, Phase I as Topic | Gene mutations | Pancreatic cancer | Physiological aspects | Genetic aspects | Research | Gene expression | Biological Sciences
Journal Article
Drug resistance updates, ISSN 1368-7646, 2015, Volume 23, pp. 55 - 68
Abstract Pancreatic ductal adenocarcinoma (PDA) ranks fourth among cancer related deaths... 
Infectious Disease | Hematology, Oncology and Palliative Medicine | Gemcitabine | Environment mediated drug resistance | Metabolism | Pancreatic ductal adenocarcinoma | Chemoresistance | PHARMACOLOGY & PHARMACY | MicroRNAs - antagonists & inhibitors | Apoptosis - drug effects | Humans | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | MicroRNAs - metabolism | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Neoplasm Proteins - metabolism | Carcinoma, Pancreatic Ductal - genetics | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Carcinoma, Pancreatic Ductal - mortality | MicroRNAs - agonists | Pancreatic Neoplasms - mortality | Neoplasm Proteins - genetics | Tumor Microenvironment - drug effects | Signal Transduction | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Enzyme Inhibitors - therapeutic use | Carcinoma, Pancreatic Ductal - drug therapy | Drug Resistance, Neoplasm - genetics | Ribonucleotide Reductases - antagonists & inhibitors | Ribonucleotide Reductases - metabolism | Survival Analysis | MicroRNAs - genetics | Ribonucleotide Reductases - genetics | Deoxycytidine - analogs & derivatives | Drug Resistance, Neoplasm - drug effects | Adenocarcinoma | Chemotherapy | Drug resistance | Cancer | Medical research | Pancreatic cancer | Medicine, Experimental | Rankings | Metastasis
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 486, Issue 7402, pp. 266 - 270
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2008, Volume 105, Issue 48, pp. 18907 - 18912
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1784 - 1794.e6
...) that progress to pancreatic ductal adenocarcinoma (PDA). We used these mice to study immune suppression in PDA... 
Gastroenterology and Hepatology | Tumor Microenvironment | Pancreatic Cancer | Listeria Vaccine | Immunity | MONOCYTOGENES | DUCTAL ADENOCARCINOMA | ONCOGENIC KRAS | CANCER | TUMORS | ADOPTIVE TRANSFER | IMMUNOTHERAPY | MOUSE MODEL | TC17 CELLS | SUPPRESSOR-CELLS | GASTROENTEROLOGY & HEPATOLOGY | Pancreatic Neoplasms - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Homeodomain Proteins - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Interferon-gamma - metabolism | Mice, 129 Strain | Carcinoma, Pancreatic Ductal - genetics | T-Lymphocytes, Regulatory - immunology | Cancer Vaccines - therapeutic use | Carcinoma in Situ - genetics | Time Factors | Forkhead Transcription Factors - metabolism | Listeria monocytogenes - metabolism | Disease Models, Animal | Carcinoma in Situ - pathology | Antibodies, Monoclonal - pharmacology | Pancreatic Neoplasms - pathology | Mice, Transgenic | Disease Progression | Interleukin-17 - metabolism | Cyclophosphamide - pharmacology | Pancreatic Neoplasms - immunology | Mice | Mutation | Carcinoma in Situ - metabolism | T-Lymphocytes, Regulatory - metabolism | Carcinoma in Situ - drug therapy | Carcinoma in Situ - immunology | Listeria monocytogenes - immunology | Tumor Suppressor Protein p53 - genetics | Pancreatic Neoplasms - drug therapy | Inflammation Mediators - metabolism | Trans-Activators - genetics | Integrases - metabolism | Carcinoma, Pancreatic Ductal - immunology | Proto-Oncogene Proteins p21(ras) - metabolism | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Tumor Suppressor Protein p53 - metabolism | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Homeodomain Proteins - genetics | Cancer Vaccines - immunology | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Listeria monocytogenes - genetics | Trans-Activators - metabolism | CD11b Antigen - metabolism | Integrases - genetics | Medical colleges | Vaccines | Listeria | Developmental biology | Pancreatic cancer | Contamination
Journal Article