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Oncogene, ISSN 0950-9232, 05/2016, Volume 35, Issue 21, pp. 2687 - 2697
Antiangiogenic therapy resistance occurs frequently in patients with metastatic renal cell carcinoma (RCC). The purpose of this study was to understand the... 
ACTIVATION | METASTASIS | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | CELL BIOLOGY | RECEPTOR TYROSINE KINASES | CABOZANTINIB XL184 | ONCOLOGY | C-MET | GROWTH | GENETICS & HEREDITY | EXPRESSION | PROGRESSION | Proto-Oncogene Proteins c-met - metabolism | Humans | Drug Resistance, Neoplasm | Molecular Targeted Therapy | Sunitinib | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Carcinoma, Renal Cell - enzymology | Indoles - pharmacology | Carcinoma, Renal Cell - drug therapy | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Carcinoma, Renal Cell - pathology | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Angiogenesis Inhibitors - pharmacology | Proto-Oncogene Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Proto-Oncogene Proteins c-met - genetics | Xenograft Model Antitumor Assays | Pyrroles - pharmacology | Animals | Receptor Protein-Tyrosine Kinases - genetics | Mice, Nude | Kidney Neoplasms - enzymology | Kidney Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Kidney Neoplasms - drug therapy | Molecular targeted therapy | Genetic aspects | Carcinoma, Renal cell | Drug therapy | Drug resistance | Properties | Phosphotransferases | Methods | Cancer therapies | Kidney cancer | Metastasis | Cabozantinib | Renal Cell Carcinoma | AXL | MET
Journal Article
Critical Reviews in Oncology / Hematology, ISSN 1040-8428, 08/2018, Volume 128, pp. 82 - 87
Journal Article
Cancer Treatment Reviews, ISSN 0305-7372, 2015, Volume 41, Issue 2, pp. 114 - 121
Highlights • Evasion of immune surveillance, a process defined immune-editing, leads to RCC malignant progression. • The PD-1/PD-L1 axis inhibition by... 
Hematology, Oncology and Palliative Medicine | PDL-1 | Renal cell carcinoma | PD-1 | Immunotherapy | DENILEUKIN DIFTITOX | RECOMBINANT INTERLEUKIN-2 | CANCER | TUMOR-INFILTRATING LYMPHOCYTES | ONCOLOGY | REGULATORY T-CELLS | ACTIVATED KILLER-CELLS | HIGH-DOSE INTERLEUKIN-2 | CLINICAL ACTIVITY | PHASE-I | Immunotherapy - methods | Prognosis | Humans | Ipilimumab | Gene Expression Regulation, Neoplastic | Kidney Neoplasms - immunology | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Carcinoma, Renal Cell - immunology | Neoplasm Grading | T-Lymphocytes - drug effects | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Carcinoma, Renal Cell - drug therapy | Antibodies, Monoclonal, Humanized - therapeutic use | Antineoplastic Agents - immunology | Carcinoma, Renal Cell - pathology | Down-Regulation | Programmed Cell Death 1 Receptor - metabolism | Clinical Trials as Topic | B7-H1 Antigen - metabolism | B7-H1 Antigen - antagonists & inhibitors | Signal Transduction - drug effects | Kidney Neoplasms - pathology | T-Lymphocytes - immunology | Cell Proliferation - drug effects | Antibody-Dependent Cell Cytotoxicity - drug effects | Kidney Neoplasms - drug therapy | Neoplasm Staging | Antimitotic agents | T cells | Antineoplastic agents | Cancer
Journal Article
Cancer Treatment Reviews, ISSN 0305-7372, 2016, Volume 49, pp. 37 - 44
Highlights • The therapeutic landscape of renal cell carcinoma (RCC) has greatly expanded in the last decade. • Clinicians are used to classify RCC based on... 
Hematology, Oncology and Palliative Medicine | Metastatic renal cell carcinoma | TKI | Precision medicine | Non-clear cell renal cell carcinoma | Targeted therapy | mTOR | PD-L1 | Clear cell renal cell carcinoma | Personalized medicine | PD-1 | SURVIVAL | FIBROBLAST-GROWTH-FACTOR | OPEN-LABEL | PHASE-II TRIAL | INTERFERON-ALPHA | IN-VITRO | ONCOLOGY | C-MET | DOUBLE-BLIND | PATIENTS PTS | INHIBITOR | AMP-Activated Protein Kinases - metabolism | Kidney Neoplasms - genetics | Glucose Transporter Type 4 - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Carcinoma, Renal Cell - genetics | Glucose Transporter Type 1 - metabolism | Kidney Neoplasms - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Molecular Targeted Therapy | Fumarate Hydratase - metabolism | TOR Serine-Threonine Kinases - genetics | Receptors, Fibroblast Growth Factor - genetics | Hepatocyte Growth Factor - genetics | Carcinoma, Renal Cell - drug therapy | Proto-Oncogene Proteins c-akt - metabolism | Precision Medicine | Signal Transduction | Epidermal Growth Factor - metabolism | B7-H1 Antigen - genetics | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins c-met - genetics | Carcinoma, Renal Cell - metabolism | Platelet-Derived Growth Factor - metabolism | Metabolic Networks and Pathways | Succinate Dehydrogenase - metabolism | Mutation | Kidney Neoplasms - drug therapy | Programmed Cell Death 1 Receptor - genetics | Antimitotic agents | Care and treatment | Carcinoma, Renal cell | Antineoplastic agents | Cancer
Journal Article