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PloS one, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e57020 - e57020
.... Therapy resistance of a tumor is thought to be related to cancer stem cells (CSCs) within the tumors. There have been indications that the lung cancer is propagated and maintained by a small population of CSCs... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Cadherins - metabolism | Vimentin - metabolism | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Antigens, CD - genetics | Antigens, CD - metabolism | Octamer Transcription Factor-3 - genetics | Small Cell Lung Carcinoma - metabolism | Adenocarcinoma - metabolism | Neoplastic Stem Cells - metabolism | Vimentin - genetics | Thy-1 Antigens - genetics | Hyaluronan Receptors - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Cadherins - genetics | Lung Neoplasms - genetics | Carcinoma, Large Cell - metabolism | Nanog Homeobox Protein | Immunophenotyping | Small Cell Lung Carcinoma - genetics | Mice, SCID | Hyaluronan Receptors - genetics | Homeodomain Proteins - genetics | Thy-1 Antigens - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Primary Cell Culture | Care and treatment | Analysis | Stem cells | Cancer cells | Physiological aspects | Research | Cancer | Adenocarcinoma | Vimentin | Cell culture | Therapy | Biotechnology | Thoracic surgery | Mesenchyme | Oct-4 protein | Lung cancer | Radiation | Population studies | Identification | Biology | mRNA | Metastasis | Cancer therapies | CD90 antigen | N-Cadherin | Immunology | CD44 antigen | Population | Medical research | Squamous cell carcinoma | Hematology | Small cell lung carcinoma | Cell division | Tumor cell lines | Gene expression | Cadherin | Spheroids | Morbidity | Medicine | Pathology | Lungs | Medical prognosis | Pancreatic cancer | Irradiation | Prostate | Tumors | Index Medicus
Journal Article
by Peifer, Martin and Fernández-Cuesta, Lynnette and Sos, Martin L and George, Julie and Seidel, Danila and Kasper, Lawryn H and Plenker, Dennis and Leenders, Frauke and Sun, Ruping and Zander, Thomas and Menon, Roopika and Koker, Mirjam and Dahmen, Ilona and Müller, Christian and Di Cerbo, Vincenzo and Schildhaus, Hans-Ulrich and Altmüller, Janine and Baessmann, Ingelore and Becker, Christian and de Wilde, Bram and Vandesompele, Jo and Böhm, Diana and Ansén, Sascha and Gabler, Franziska and Wilkening, Ines and Heynck, Stefanie and Heuckmann, Johannes M and Lu, Xin and Carter, Scott L and Cibulskis, Kristian and Banerji, Shantanu and Getz, Gad and Park, Kwon-Sik and Rauh, Daniel and Grütter, Christian and Fischer, Matthias and Pasqualucci, Laura and Wright, Gavin and Wainer, Zoe and Russell, Prudence and Petersen, Iver and Chen, Yuan and Stoelben, Erich and Ludwig, Corinna and Schnabel, Philipp and Hoffmann, Hans and Muley, Thomas and Brockmann, Michael and Engel-Riedel, Walburga and Muscarella, Lucia A and Fazio, Vito M and Groen, Harry and Timens, Wim and Sietsma, Hannie and Thunnissen, Erik and Smit, Egbert and Heideman, Daniëlle A M and Snijders, Peter J F and Cappuzzo, Federico and Ligorio, Claudia and Damiani, Stefania and Field, John and Solberg, Steinar and Brustugun, Odd Terje and Lund-Iversen, Marius and Sänger, Jörg and Clement, Joachim H and Soltermann, Alex and Moch, Holger and Weder, Walter and Solomon, Benjamin and Soria, Jean-Charles and Validire, Pierre and Besse, Benjamin and Brambilla, Elisabeth and Brambilla, Christian and Lantuejoul, Sylvie and Lorimier, Philippe and Schneider, Peter M and Hallek, Michael and Pao, William and Meyerson, Matthew and Sage, Julien and Shendure, Jay and Schneider, Robert and Büttner, Reinhard and Wolf, Jürgen and Nürnberg, Peter and Perner, Sven and Heukamp, Lukas C and Brindle, Paul K and Haas, Stefan and Thomas, Roman K
Nature genetics, ISSN 1546-1718, 09/2012, Volume 44, Issue 10, pp. 1104 - 1110
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 5110 - 13
Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Endoribonucleases - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | MicroRNAs - metabolism | Activating Transcription Factor 6 - genetics | Tumor Suppressor Protein p53 - genetics | In Situ Hybridization | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - physiology | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Endoribonucleases - metabolism | Unfolded Protein Response - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Endoplasmic Reticulum-Associated Degradation - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Cell Proliferation - physiology | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Xenograft Model Antitumor Assays | Activating Transcription Factor 6 - metabolism | Animals | Endoplasmic Reticulum-Associated Degradation - physiology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Ubiquitin-Protein Ligases - genetics | Unfolded Protein Response - physiology | Small cell lung carcinoma | p53 Protein | Lung cancer | Non-small cell lung carcinoma | Lung carcinoma | Metastasis | Substrates | Metastases | Proteins | Protein folding | Chromosome 8 | Tumor suppressor genes | miRNA | Solid tumors | Tumors | Cancer | Index Medicus
Journal Article
Annals of surgical oncology, ISSN 1068-9265, 3/2010, Volume 17, Issue 3, pp. 889 - 897
Journal Article
Cancer discovery, ISSN 2159-8290, 03/2017, Volume 7, Issue 3, pp. 264 - 276
.... We have examined the evolving landscape of tumor neoantigens during the emergence of acquired resistance in patients with non-small cell lung cancer after initial response to immune checkpoint... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Lung Neoplasms - pathology | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Ipilimumab - pharmacology | Immunotherapy | Ipilimumab - therapeutic use | Janus Kinase 1 - genetics | Adult | Female | Receptors, Antigen, T-Cell - immunology | Cell Cycle Checkpoints - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptors, Antigen, T-Cell - metabolism | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Antibodies, Monoclonal - pharmacology | Janus Kinase 2 - genetics | CTLA-4 Antigen - genetics | Drug Resistance, Neoplasm - immunology | Lung Neoplasms - therapy | CTLA-4 Antigen - immunology | Antineoplastic Agents, Immunological - pharmacology | Carcinoma, Non-Small-Cell Lung - immunology | Carcinoma, Non-Small-Cell Lung - therapy | Drug Resistance, Neoplasm - genetics | Lung Neoplasms - immunology | Antineoplastic Agents, Immunological - therapeutic use | Cell Cycle Checkpoints - drug effects | Receptors, Antigen, T-Cell - genetics | Mutation | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Cohort Studies | Index Medicus
Journal Article
PLoS genetics, ISSN 1553-7404, 12/2018, Volume 14, Issue 12, pp. e1007790 - e1007790
.... In this study, we identified a novel miRNA, miR-3607-3p, and its targets in non-small cell lung cancer (NSCLC... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | RNA, Small Nucleolar - antagonists & inhibitors | Cell Cycle - genetics | Prognosis | Humans | Middle Aged | Neoplasm Invasiveness - prevention & control | Cyclins - genetics | Lung Neoplasms - pathology | Male | Receptor, Transforming Growth Factor-beta Type I - antagonists & inhibitors | Cell Movement - genetics | Gene Knockdown Techniques | Neoplasm Metastasis | Female | Biomarkers, Tumor - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Proliferation - genetics | Cyclins - antagonists & inhibitors | RNA, Small Nucleolar - blood | Carcinoma, Non-Small-Cell Lung - genetics | Down-Regulation | Lung Neoplasms - therapy | RNA, Small Nucleolar - genetics | Biomarkers, Tumor - blood | Carcinoma, Non-Small-Cell Lung - therapy | Animals | Mice, Nude | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | Mice | Neoplasm Invasiveness - genetics | Receptor, Transforming Growth Factor-beta Type I - genetics | Genetic aspects | MicroRNA | Diagnosis | Research | Gene expression | Lung cancer | Cell proliferation | Pathogenesis | Therapeutic applications | Invasiveness | Non-small cell lung carcinoma | Oncology | Breast cancer | Metastasis | Kinases | Stomach cancer | Western blotting | Metastases | Medical prognosis | MicroRNAs | Xenografts | Cell cycle | Biomarkers | miRNA | Growth factors | Cell migration | Apoptosis | Index Medicus
Journal Article