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1. Full Text Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression
by Xu, Chunxiao and Fillmore, Christine M and Koyama, Shohei and Wu, Hongbo and Zhao, Yanqiu and Chen, Zhao and Herter-Sprie, Grit S and Akbay, Esra A and Tchaicha, Jeremy H and Altabef, Abigail and Reibel, Jacob B and Walton, Zandra and Ji, Hongbin and Watanabe, Hideo and Jänne, Pasi A and Castrillon, Diego H and Rustgi, Anil K and Bass, Adam J and Freeman, Gordon J and Padera, Robert F and Dranoff, Glenn and Hammerman, Peter S and Kim, Carla F and Wong, Kwok-Kin
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 590 - 604
Lung squamous cell carcinoma (SCC) is a deadly disease for which current treatments are inadequate. We demonstrate that biallelic inactivation of and in the... 
STEM-CELLS | ONCOLOGY | ADENOCARCINOMA | INFLAMMATION | MECHANISMS | INFECTION | SUPPRESSOR-CELLS | DIFFERENTIATION | IDENTIFICATION | CANCER | PROGRESSION | CELL BIOLOGY | Carcinoma, Squamous Cell - genetics | Lymphocyte Activation - immunology | Antigens, Ly - biosynthesis | Immune Tolerance - immunology | Killer Cells, Natural - immunology | Transcription, Genetic | Lung - metabolism | Trans-Activators - biosynthesis | Tumor Cells, Cultured | Macrophages - immunology | Disease Models, Animal | Tumor Escape - immunology | Lung Neoplasms - genetics | PTEN Phosphohydrolase - genetics | Phosphoproteins - biosynthesis | Keratin-5 - biosynthesis | Neutrophils - immunology | Protein-Serine-Threonine Kinases - genetics | Metabolome | Receptor, Nerve Growth Factor - biosynthesis | SOXB1 Transcription Factors - biosynthesis | Carcinoma, Squamous Cell - immunology | Lung Neoplasms - immunology | Membrane Proteins - biosynthesis | Animals | B-Lymphocytes - immunology | Keratin-15 | B7-H1 Antigen - biosynthesis | T-Lymphocytes - immunology | Mice | Squamous cell carcinoma | Gene expression | Analysis | Stem cells | Index Medicus
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2. Full Text Cd44+ cells in head and neck squamous cell carcinoma suppress t-cell-mediated immunity by selective constitutive and inducible expression of PD-L1
by Lee, Yunqin and Shin, June Ho and Longmire, Michelle and Wang, Hua and Kohrt, Holbrook E and Chang, Howard Y and Sunwoo, John B
Clinical Cancer Research, ISSN 1078-0432, 07/2016, Volume 22, Issue 14, pp. 3571 - 3581
Purpose: Humantumors consist of heterogeneous populations of cells with distinct marker expression and functional properties. In squamous cell carcinoma of the... 
EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | ACTIVATION | MELANOMA | ONCOLOGY | MOLECULE | STAT3 | SELF-RENEWAL | ANTITUMOR IMMUNITY | TUMOR-INITIATING CELLS | CANCER STEM-CELLS | Carcinoma, Squamous Cell - metabolism | Epithelial-Mesenchymal Transition - physiology | Humans | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - metabolism | B7-H1 Antigen - metabolism | Head and Neck Neoplasms - immunology | STAT1 Transcription Factor - metabolism | Squamous Cell Carcinoma of Head and Neck | Animals | Epithelial-Mesenchymal Transition - immunology | Hyaluronan Receptors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | STAT3 Transcription Factor - metabolism | Index Medicus | SCCHN | Immune evasion | cancer stem cells | immune suppression | oral cancer | tumor heterogeneity
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3. Full Text Immunosuppressive activity of CD14+ HLA‐DR− cells in squamous cell carcinoma of the head and neck
by Chikamatsu, Kazuaki and Sakakura, Koichi and Toyoda, Minoru and Takahashi, Katsumasa and Yamamoto, Takanori and Masuyama, Keisuke
Cancer Science, ISSN 1347-9032, 06/2012, Volume 103, Issue 6, pp. 976 - 983
Myeloid‐derived suppressor cells ( MDSC ) represent a heterogeneous population and have the potential to suppress immune responses via diverse mechanisms. In... 
MYELOID SUPPRESSOR-CELLS | ONCOLOGY | REGULATORY T-CELLS | MONOCYTES | PROLIFERATION | MECHANISMS | DIFFERENTIATION | EVASION | CANCER | REVERSAL | Cell Proliferation | Humans | Middle Aged | Male | Lipopolysaccharide Receptors - analysis | Squamous Cell Carcinoma of Head and Neck | Myeloid Cells - immunology | Aged, 80 and over | Adult | Female | B7-2 Antigen - immunology | HLA-DR Antigens - metabolism | Antibodies, Monoclonal - immunology | Transforming Growth Factor beta - immunology | Cells, Cultured | B7-2 Antigen - analysis | Lipopolysaccharide Receptors - immunology | B7-H1 Antigen - immunology | Carcinoma, Squamous Cell - immunology | Interleukin-7 Receptor alpha Subunit - analysis | Head and Neck Neoplasms - immunology | Interleukin-2 Receptor alpha Subunit - analysis | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Aged | B7-H1 Antigen - analysis | HLA-DR Antigens - immunology | Interferon-gamma - biosynthesis | Index Medicus
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4. Full Text Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
by Lyford-Pike, Sofia and Peng, Shiwen and Young, Geoffrey D and Taube, Janis M and Westra, William H and Akpeng, Belinda and Bruno, Tullia C and Richmon, Jeremy D and Wang, Hao and Bishop, Justin A and Chen, Lieping and Drake, Charles G and Topalian, Suzanne L and Pardoll, Drew M and Pai, Sara I
Cancer Research, ISSN 0008-5472, 03/2013, Volume 73, Issue 6, pp. 1733 - 1741
Human papillomavirus-associated head and neck squamous cell carcinomas (HPV-HNSCC) originate in the tonsils, the major lymphoid organ that orchestrates... 
SURVIVAL | OROPHARYNGEAL | ONCOLOGY | SAFETY | B7-H1 EXPRESSION | PTEN | ANTIBODY | HUMAN-PAPILLOMAVIRUS | BLOCKADE | CANCER | T-CELLS | Immunohistochemistry | B7-H1 Antigen - physiology | Head and Neck Neoplasms - virology | Carcinoma, Squamous Cell - virology | Humans | Interferon-gamma - metabolism | Papillomaviridae - isolation & purification | Programmed Cell Death 1 Receptor - physiology | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - immunology | Flow Cytometry | CD8-Positive T-Lymphocytes - immunology | Index Medicus | immune checkpoint | PD-L1 | oropharyngeal cancers | squamous cell carcinomas | adapative resistance | PD-1 | head and neck cancers | HPV
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5. Full Text Ox40+ regulatory T cells in cutaneous squamous cell carcinoma suppress effector T-cell responses and associate with metastatic potential
by Lai, Chester and August, Suzannah and Albibas, Amel and Behar, Ramnik and Cho, Shin-Young and Polak, Marta E and Theaker, Jeffrey and Macleod, Amanda S and French, Ruth R and Glennie, Martin J and Al-Shamkhani, Aymen and Healy, Eugene
Clinical Cancer Research, ISSN 1078-0432, 08/2016, Volume 22, Issue 16, pp. 4236 - 4248
Purpose: Cutaneous squamous cell carcinoma (cSCC) is the most common In-flan cancer with metastatic potential. Despite T cells accumulating around cSCCs, these... 
TUMOR-INFILTRATING LYMPHOCYTES | INDIVIDUALS | RECRUITMENT | CANCER-PATIENTS | MELANOMA | ONCOLOGY | LYMPH-NODE | SKIN | EXPRESSION | CD134 | PROGRESSION | Immunohistochemistry | Skin Neoplasms - pathology | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Receptors, OX40 - agonists | Skin Neoplasms - immunology | Immunomodulation | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Immunophenotyping | Carcinoma, Squamous Cell - immunology | Skin Neoplasms - metabolism | T-Lymphocytes, Regulatory - immunology | Lymphocyte Activation - immunology | Neoplasm Metastasis | Phenotype | Receptors, OX40 - metabolism | T-Lymphocyte Subsets - metabolism | Biomarkers | Lymphocyte Count | Immunologic Memory | Lymphocytes, Tumor-Infiltrating - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
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6. Full Text Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
by Duhen, Thomas and Duhen, Rebekka and Montler, Ryan and Moses, Jake and Moudgil, Tarsem and De Miranda, Noel F and Goodall, Cheri P and Blair, Tiffany C and Fox, Bernard A and McDermott, Jason E and Chang, Shu-Ching and Grunkemeier, Gary and Leidner, Rom and Bell, Richard Bryan and Weinberg, Andrew D and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2724 - 13
Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that... 
TGF-BETA | MELANOMA | THERAPY | MEMORY | CANCER REGRESSION | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | PD-1 | EXPRESSION | EXHAUSTION | ANTIGEN | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Adenocarcinoma of Lung - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Ovarian Neoplasms - pathology | Transcriptome | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Squamous Cell Carcinoma of Head and Neck - mortality | Ovarian Neoplasms - mortality | Antigens, CD - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Ovarian Neoplasms - genetics | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Carcinoma, Squamous Cell - mortality | Melanoma - genetics | Integrin alpha Chains - immunology | Female | Adenocarcinoma of Lung - immunology | Apyrase - immunology | Immunophenotyping | Melanoma - pathology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8 Antigens - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | Apyrase - genetics | CD8 Antigens - genetics | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Melanoma - mortality | Ovarian Neoplasms - immunology | Head | Phenotypes | Tumor cells | CD8 antigen | T cell receptors | Lymphocytes T | Patients | Metastases | T-cell receptor | CD103 antigen | Major histocompatibility complex | Lymphocytes | Immunotherapy | Head and neck cancer | Neck | Solid tumors | Cancer | Tumors | Index Medicus | BASIC BIOLOGICAL SCIENCES
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7. Full Text Clinical impact of serum exosomal microRNA‐21 as a clinical biomarker in human esophageal squamous cell carcinoma
by Tanaka, Youhei and Kamohara, Hidenobu and Kinoshita, Kouichi and Kurashige, Junji and Ishimoto, Takatsugu and Iwatsuki, Masaaki and Watanabe, Masayuki and Baba, Hideo
Cancer, ISSN 0008-543X, 03/2013, Volume 119, Issue 6, pp. 1159 - 1167
BACKGROUND: Exosomes are 40-nm to 100-nm membrane vesicles that are secreted by various cells, and they play a major role in cell-cell communication. The... 
microRNA | human microRNA‐21 | esophageal cancer | exosome | human microRNA-21 | SURVIVAL | RNA | VESICLES | MICROVESICLES | MECHANISMS | DIAGNOSTIC BIOMARKERS | TUMOR-DERIVED EXOSOMES | CANCER | ONCOLOGY | ASSOCIATION | EXPRESSION | Carcinoma, Squamous Cell - blood | Up-Regulation | Carcinoma, Squamous Cell - genetics | Esophageal Neoplasms - blood | Humans | Middle Aged | Exosomes - genetics | Male | Inflammation - immunology | Carcinoma, Squamous Cell - immunology | Esophageal Neoplasms - immunology | Disease Progression | Biomarkers, Tumor - blood | Esophageal Neoplasms - genetics | Cell Line, Tumor | Female | Aged | Exosomes - chemistry | MicroRNAs - blood | Esophageal Squamous Cell Carcinoma | Care and treatment | MicroRNA | Research | Health aspects | Esophageal cancer | Cancer | Index Medicus | Abridged Index Medicus
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8. Full Text PD-L2 expression in human tumors: Relevance to anti-PD-1 therapy in cancer
by Yearley, Jennifer H and Gibson, Christopher and Yu, Ni and Moon, Christina and Murphy, Erin and Juco, Jonathan and Lunceford, Jared and Cheng, Jonathan and Chow, Laura Q.M and Seiwert, Tanguy Y and Handa, Masahisa and Tomassini, Joanne E and McClanahan, Terrill
Clinical Cancer Research, ISSN 1078-0432, 06/2017, Volume 23, Issue 12, pp. 3158 - 3167
Purpose: Tumor-associated PD-L1 expression is predictive of clinical response to PD-1-directed immunotherapy. However, PD-L1-negative patients may also respond... 
RESPONSES | PEMBROLIZUMAB | ONCOLOGY | ADVANCED MELANOMA | SAFETY | DEATH-LIGAND 1 | ANTIBODY | NIVOLUMAB | BLOCKADE | CLINICAL ACTIVITY | IPILIMUMAB | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Squamous Cell Carcinoma of Head and Neck | Antibodies, Monoclonal, Humanized - administration & dosage | Immunotherapy | Aged, 80 and over | Adult | Female | Programmed Cell Death 1 Ligand 2 Protein - genetics | Head and Neck Neoplasms - drug therapy | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - pathology | Programmed Cell Death 1 Ligand 2 Protein - immunology | Disease-Free Survival | Head and Neck Neoplasms - immunology | Carcinoma, Squamous Cell - drug therapy | Head and Neck Neoplasms - genetics | Aged | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Ligand 2 Protein - antagonists & inhibitors | Therapy | Squamous cell carcinoma | Head | PD-1 protein | Tissues | Survival | Patients | Endothelial cells | Metastases | Immune systems | Immune checkpoint | Experimental design | PD-L1 protein | Head and neck cancer | Ligands | Neck | Tumors | Cancer | Index Medicus
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9. Full Text A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17+ cell frequency
by Punt, Simone and nkers, Emilie C and Welters, M and Goedemans, Renske and Koljenovi, Senada and Bloemena, Elisabeth and Snijders, Peter and Gorter, Arko and Burg, Sjoerd and Baatenburg de Jong, Robert Jan and Jordanova, Ekaterina S
Cancer Immunology, Immunotherapy: other biological response modifications, ISSN 0340-7004, 04/2016, Volume 65, Issue 4, pp. 393 - 403
textabstractPatients with HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) have a better prognosis than patients with non-HPV-induced OPSCC. The... 
Head and neck cancer | Th17 cell | Tumor microenvironment | T cell | IL-17 | Treg | SURVIVAL | HEAD | PROGNOSIS | INFILTRATING LYMPHOCYTES | CERVICAL-CANCER | PREVALENCE | IMMUNOLOGY | CLINICAL-RELEVANCE | NECK CANCERS | ONCOLOGY | HUMAN-PAPILLOMAVIRUS STATUS | TH17 CELLS | Forkhead Transcription Factors - immunology | Oropharyngeal Neoplasms - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Middle Aged | Interleukin-17 - immunology | Male | T-Lymphocytes, Regulatory - immunology | Papillomaviridae - immunology | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Aged, 80 and over | Papillomavirus Infections - immunology | Adult | Female | Papillomavirus Infections - virology | Granulocytes - metabolism | Papillomavirus Infections - complications | Kaplan-Meier Estimate | CD3 Complex - metabolism | Carcinoma, Squamous Cell - immunology | Oropharyngeal Neoplasms - complications | Tumor Microenvironment - immunology | Interleukin-17 - metabolism | Microscopy, Confocal | Carcinoma, Squamous Cell - complications | CD3 Complex - immunology | Lymphocyte Count | Th17 Cells - immunology | T-Lymphocytes - immunology | Aged | Granulocytes - immunology | Index Medicus | Original
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10. Full Text B Cells Regulate Macrophage Phenotype and Response to Chemotherapy in Squamous Carcinomas
by Affara, Nesrine I and Ruffell, Brian and Medler, Terry R and Gunderson, Andrew J and Johansson, Magnus and Bornstein, Sophia and Bergsland, Emily and Steinhoff, Martin and Li, Yijin and Gong, Qian and Ma, Yan and Wiesen, Jane F and Wong, Melissa H and Kulesz-Martin, Molly and Irving, Bryan and Coussens, Lisa M
Cancer Cell, ISSN 1535-6108, 06/2014, Volume 25, Issue 6, pp. 809 - 821
B cells foster squamous cell carcinoma (SCC) development through deposition of immunoglobulin-containing immune complexes in premalignant tissue and Fcγ... 
BREAST-CANCER | IMMUNITY | ONCOLOGY | OROPHARYNGEAL CANCER | MOUSE MODEL | SKIN CARCINOGENESIS | CERVICAL-CANCER | HUMAN-PAPILLOMAVIRUS | RESISTANT PROSTATE-CANCER | K14-HPV16 TRANSGENIC MICE | T-CELLS | CELL BIOLOGY | CD8-Positive T-Lymphocytes - pathology | Cricetulus | Carcinoma, Squamous Cell - pathology | Humans | Tumor Microenvironment | Organoplatinum Compounds - administration & dosage | Female | B-Lymphocytes - pathology | Paclitaxel - administration & dosage | Macrophages - immunology | CHO Cells | Macrophages - pathology | Mice, Transgenic | Carcinoma, Squamous Cell - immunology | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | B-Lymphocytes - drug effects | Phenotype | Animals | B-Lymphocytes - immunology | Carcinoma, Squamous Cell - drug therapy | Lymphocytes, Tumor-Infiltrating - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasms - immunology | Macrophages - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - immunology | Antimitotic agents | Squamous cell carcinoma | Chemotherapy | Developmental biology | Nuclear radiation | Monoclonal antibodies | Genetic aspects | B cells | Antineoplastic agents | Macrophages | Cancer | Index Medicus | CD8 T cell | CD20 | B cell | humoral immunity | immunoglobulin | inflammation | macrophage | chemotherapy
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11. Full Text PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-Associated head and neck cancer
by Badoual, Cécile and Hans, Stéphane and Merillon, Nathalie and Van Ryswick, Cordéli and Ravel, Patrice and Benhamouda, Nadine and Levionnois, Emeline and Nizard, Mevyn and Si-Mohamed, Ali and Besnier, Nicolas and Gey, Alain and Rotem-Yehudar, Rinat and Pere, Hél̀ene and Tran, Thi and Guerin, Coralie L and Chauvat, Anne and Dransart, Estelle and Alanio, Cécile and Albert, Sebastien and Barry, Beatrix and Sandoval, Federico and Quintin-Colonna, Françoise and Bruneval, Patrick and Fridman, Wolf H and Lemoine, Francois M and Oudard, Stephane and Johannes, Ludger and Olive, Daniel and Brasnu, Daniel and Tartour, Eric
Cancer Research, ISSN 0008-5472, 01/2013, Volume 73, Issue 1, pp. 128 - 138
Head and neck cancers positive for human papillomavirus (HPV) have a more favorable clinical outcome than HPV-negative cancers, but it is unknown why this is... 
HIGH NUMBERS | ANTI-PD-1 ANTIBODY | ONCOLOGY | OROPHARYNGEAL CANCER | FOLLICULAR LYMPHOMA | HUMAN-PAPILLOMAVIRUS | ANTITUMOR IMMUNITY | UP-REGULATION | CARCINOMA | PD-1 EXPRESSION | LYMPHOCYTES | T-Lymphocyte Subsets - immunology | Head and Neck Neoplasms - virology | Prognosis | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - virology | Humans | Head and Neck Neoplasms - metabolism | Lymphocyte Activation - immunology | Flow Cytometry | Programmed Cell Death 1 Receptor - biosynthesis | Biomarkers, Tumor - metabolism | Papillomavirus Infections - immunology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Papillomavirus Infections - complications | Mice, Inbred C57BL | Carcinoma, Squamous Cell - immunology | Tumor Microenvironment - immunology | Head and Neck Neoplasms - immunology | Animals | Papillomavirus Infections - metabolism | Fluorescent Antibody Technique | T-Lymphocytes - immunology | Mice | Programmed Cell Death 1 Receptor - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
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12. Full Text IL-6-stimulated CD11b+CD14+HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus
by Chen, Miao-Fen and Kuan, Feng-Che and Yen, Tzu-Chen and Lu, Ming- Shian and Lin, Paul- Yang and Chung, Yi-Hsiu and Chen, Wen-Cheng and Lee, Kuan-Der
Oncotarget, ISSN 1949-2553, 2014, Volume 5, Issue 18, pp. 8716 - 8728
The aim of this study was to assess the significance of myeloid-derived suppressor cells (MDSCs) and their association with IL-6 in esophageal squamous cell... 
Esophageal SCC | IL-6 | MDSC | Index Medicus
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13. Full Text Hyperprogression during anti-PD-1/PD-L1 therapy in patients with recurrent and/or metastatic head and neck squamous cell carcinoma
by Saâda-Bouzid, E and Defaucheux, C and Karabajakian, A and Coloma, V.P and Servois, V and Paoletti, X and Even, C and Fayette, J and Guigay, J and Loirat, D and Peyrade, F and Alt, M and Gal, J and Le Tourneau, C
Annals of oncology : official journal of the European Society for Medical Oncology, ISSN 0923-7534, 07/2017, Volume 28, Issue 7, pp. 1605 - 1611
Background: Pembrolizumab and nivolumab are immune checkpoint inhibitors targeting PD-1 that have recently been approved in pretreated recurrent and/or... 
hyperprogression | immune checkpoint inhibitors | tumor growth kinetics | HNSCC | immunotherapy | RECIST | OPEN-LABEL | CANCER | TUMORS | CHEMOTHERAPY | ONCOLOGY | GROWTH | NIVOLUMAB | PROGRESSION | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Time Factors | Female | Retrospective Studies | Antibodies, Monoclonal, Humanized - adverse effects | Risk Factors | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Treatment Outcome | B7-H1 Antigen - immunology | Carcinoma, Squamous Cell - immunology | Disease Progression | Head and Neck Neoplasms - pathology | Disease-Free Survival | Antineoplastic Agents, Immunological - adverse effects | Head and Neck Neoplasms - immunology | B7-H1 Antigen - antagonists & inhibitors | Carcinoma, Squamous Cell - drug therapy | Tumor Burden - drug effects | Nivolumab | Carcinoma, Squamous Cell - secondary | Head and Neck Neoplasms - mortality | Programmed Cell Death 1 Receptor - immunology | Index Medicus
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