X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1326) 1326
cardiomegaly - enzymology (895) 895
rats (757) 757
male (693) 693
myocardium - enzymology (655) 655
index medicus (470) 470
cardiomegaly - pathology (451) 451
humans (422) 422
mice (398) 398
cardiac & cardiovascular systems (382) 382
cardiomegaly - physiopathology (371) 371
cardiomegaly - metabolism (351) 351
hypertrophy (314) 314
myocardium - pathology (289) 289
cardiomegaly - etiology (255) 255
myocardium - metabolism (255) 255
cardiomegaly - genetics (249) 249
cardiac hypertrophy (240) 240
peripheral vascular disease (229) 229
myocytes, cardiac - enzymology (227) 227
cell biology (224) 224
disease models, animal (223) 223
heart (223) 223
rats, sprague-dawley (211) 211
cells, cultured (210) 210
female (210) 210
signal transduction (200) 200
heart-failure (197) 197
expression (180) 180
phosphorylation (174) 174
cardiomegaly - chemically induced (173) 173
myocytes, cardiac - pathology (172) 172
cardiomegaly - prevention & control (168) 168
time factors (160) 160
mice, inbred c57bl (155) 155
physiology (155) 155
mice, knockout (152) 152
heart failure (142) 142
mice, transgenic (140) 140
biochemistry & molecular biology (139) 139
myocytes, cardiac - drug effects (135) 135
rats, wistar (135) 135
gene-expression (121) 121
cardiac-hypertrophy (120) 120
fibrosis (120) 120
article (116) 116
activation (115) 115
hematology (115) 115
heart failure - enzymology (111) 111
hypertension (111) 111
cardiomegaly - drug therapy (103) 103
pressure-overload (103) 103
rats, inbred strains (103) 103
heart enlargement (102) 102
enzyme activation (101) 101
pharmacology & pharmacy (100) 100
animals, newborn (98) 98
apoptosis (97) 97
organ size (96) 96
hypertension - enzymology (95) 95
in-vivo (93) 93
oxidative stress (92) 92
heart - drug effects (91) 91
signal transduction - drug effects (89) 89
gene expression (88) 88
myocytes, cardiac - metabolism (86) 86
rna, messenger - metabolism (86) 86
blood pressure (85) 85
physiological aspects (85) 85
blood pressure - drug effects (84) 84
adenosine triphosphatases - metabolism (83) 83
isoenzymes - metabolism (83) 83
cardiomyocytes (81) 81
inhibition (78) 78
heart ventricles - enzymology (77) 77
myocardial contraction (76) 76
calcium - metabolism (75) 75
heart - physiopathology (75) 75
myocardium - cytology (73) 73
myocytes (73) 73
myosins - metabolism (73) 73
cardiovascular system (72) 72
enzyme inhibitors - pharmacology (72) 72
hypertension - complications (70) 70
rats, inbred shr (69) 69
angiotensin-ii (68) 68
hypertension - physiopathology (68) 68
cardiomegaly - complications (67) 67
heart failure - physiopathology (67) 67
myocardial-infarction (67) 67
angiotensin ii (66) 66
left-ventricular hypertrophy (65) 65
transfection (65) 65
cardiomyopathy (63) 63
protein kinase c - metabolism (63) 63
proteins (63) 63
isoproterenol - pharmacology (62) 62
rats, inbred wky (59) 59
rodents (59) 59
angiotensin ii - pharmacology (58) 58
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1407) 1407
Japanese (26) 26
Russian (23) 23
German (16) 16
Chinese (8) 8
French (8) 8
Italian (6) 6
Bulgarian (3) 3
Czech (1) 1
Polish (1) 1
Portuguese (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2014, Volume 63, Issue 24, pp. 2734 - 2741
Objectives This study sought to investigate the effect of endothelial dysfunction on the development of cardiac hypertrophy and fibrosis. Background... 
Cardiovascular | Internal Medicine | endothelial-mesenchymal transition | diastolic dysfunction | endothelium | NADPH (nicotinamide adenine dinucleotide phosphate) oxidase | angiotensin II | CELLS | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | HEART-FAILURE | ATHEROSCLEROSIS | ANGIOTENSIN-II | PATHOPHYSIOLOGY | HYPERTROPHY | MICE | CONTRIBUTES | Heart Failure, Diastolic - genetics | Mesenchymal Stromal Cells - enzymology | Humans | Cardiomegaly - pathology | Male | Endothelium, Vascular - enzymology | Membrane Glycoproteins - physiology | Ventricular Dysfunction, Left - genetics | Ventricular Dysfunction, Left - pathology | NADPH Oxidases - genetics | Ventricular Dysfunction, Left - enzymology | Inflammation Mediators - physiology | Fibrosis - genetics | Fibrosis - enzymology | Cells, Cultured | Heart Failure, Diastolic - enzymology | Mice, Transgenic | Cardiomegaly - enzymology | Heart Failure, Diastolic - pathology | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Animals | Endothelium, Vascular - pathology | Mice | Fibrosis - pathology | Mesenchymal Stromal Cells - pathology | Cardiomegaly - genetics | NADPH Oxidases - physiology | Oxidases | Heart | Fibrosis | Stem cells | Endothelium | Hypertension | Heart failure | Genotype & phenotype | Stroke | Heart attacks | Pathogenesis | Rodents | Cardiomyocytes | Variance analysis
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6656
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective... 
METABOLISM | GENE | SIRT3-MEDIATED DEACETYLATION | PATHWAY | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | HOMOLOG | AKT | SIRTUINS | CALORIE RESTRICTION | CELL-DEATH | Mitochondria - enzymology | Fibroblasts - enzymology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Myofibroblasts - enzymology | Superoxide Dismutase - antagonists & inhibitors | Cardiomegaly - pathology | Isoproterenol | Lignans - pharmacology | Myocytes, Cardiac - enzymology | Phenylephrine - pharmacology | Biphenyl Compounds - pharmacology | Membrane Proteins - metabolism | Superoxide Dismutase - metabolism | Myofibroblasts - pathology | Sirtuin 3 - genetics | Signal Transduction | Membrane Proteins - genetics | Carrier Proteins - antagonists & inhibitors | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Myocardium - pathology | Cardiotonic Agents - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Fibroblasts - pathology | Myofibroblasts - drug effects | Adenosine Triphosphatases - antagonists & inhibitors | Carrier Proteins - genetics | Myocytes, Cardiac - pathology | Acetylation - drug effects | Myocardium - enzymology | Reactive Oxygen Species - antagonists & inhibitors | Animals | Cardiomegaly - prevention & control | Carrier Proteins - metabolism | Myocytes, Cardiac - drug effects | Membrane Proteins - antagonists & inhibitors | Cell Differentiation - drug effects | Fibroblasts - drug effects | Cardiomegaly - chemically induced | Adenosine Triphosphatases - genetics | Cell Proliferation - drug effects | Mice | Enzyme Activation | Primary Cell Culture | Cardiomegaly - genetics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 52, pp. 40819 - 40829
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2016, Volume 310, Issue 8, pp. H962 - H972
Doxorubicin (Doxo) is a chemotherapeutic drug widely used to treat variety of cancers. One of the most serious side effects of Doxo is its dose-dependent and... 
Sirt3 | Mitochondria | Doxorubicin | ROS | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | mitochondria | CARDIOTOXICITY | CARDIOMYOCYTES | CELL-DEATH | REPAIR | REACTIVE OXYGEN | SIRT3-MEDIATED DEACETYLATION | PERIPHERAL VASCULAR DISEASE | doxorubicin | ANTHRACYCLINES | CARDIAC MITOCHONDRIA | CALORIE RESTRICTION | Fibroblasts - enzymology | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Oxidative Stress | Mitochondria, Heart - pathology | Cardiomegaly - pathology | Cardiomyopathies - prevention & control | Male | Sirtuin 3 - deficiency | Cardiomyopathies - enzymology | DNA Adducts - metabolism | Myocytes, Cardiac - enzymology | Cardiomyopathies - genetics | DNA, Mitochondrial - genetics | Time Factors | Cell Death | Female | DNA Glycosylases - metabolism | Deoxyguanosine - analogs & derivatives | Disease Models, Animal | Sirtuin 3 - genetics | DNA, Mitochondrial - metabolism | Cells, Cultured | Mitochondria, Heart - enzymology | Cardiomyopathies - pathology | Cardiomegaly - enzymology | Fibroblasts - pathology | Rats, Sprague-Dawley | Mice, Knockout | Hydrolysis | Myocytes, Cardiac - pathology | Animals | Cardiomegaly - chemically induced | Deoxyguanosine - metabolism | DNA Damage | Cardiomegaly - genetics | Sirtuins - metabolism | Cardiomyopathies - chemically induced | Index Medicus | Signaling and Stress Response
Journal Article
Circulation, ISSN 0009-7322, 07/2011, Volume 124, Issue 4, pp. 406 - 415
Background-Cardiac overload, a major cause of heart failure, induces the expression of the heat shock protein H11 kinase/Hsp22 (Hsp22). Methods and Results-To... 
physiology | heart failure | heat-shock proteins | signal transduction | models, theoretical | LIFE-SPAN | PRESSURE-OVERLOAD | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | SERINE PHOSPHORYLATION | CHAPERONE | HYPERTROPHY | IN-VIVO | PROTEASOME | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | PROMOTES | Heart Failure - enzymology | HSP20 Heat-Shock Proteins - genetics | Male | NF-kappa B - metabolism | Gene Expression Profiling | Cell Nucleus - enzymology | Myocytes, Cardiac - enzymology | Gene Deletion | Mitochondria, Heart - genetics | STAT3 Transcription Factor - genetics | Heart Failure - mortality | Cells, Cultured | Mitochondria, Heart - enzymology | Oxidative Phosphorylation | Rats | Heart Failure - genetics | Cardiomegaly - enzymology | Mice, Knockout | Muscle Proteins - genetics | Collagen - metabolism | Animals | Cell Nucleus - genetics | Interleukin-6 - biosynthesis | Mice | Cardiomegaly - genetics | Heart failure | Physiological aspects | Heat shock proteins | Genetic aspects | Research | Gene expression | Phosphotransferases | Risk factors | Interleukin-6 | Cardiomegaly | Muscle Proteins | genetics | NF-kappa B | biosynthesis | Mitochondria, Heart | Heart Failure | Myocytes, Cardiac | enzymology | STAT | HSP20 Heat-Shock Proteins | Overload | Collagen | mortality | metabolism | STAT3 Transcription Factor | Cell Nucleus
Journal Article
Circulation Research, ISSN 0009-7330, 04/2010, Volume 106, Issue 7, pp. 1253 - 1264
RATIONALE:NADPH oxidases are a major source of superoxide (O2) in the cardiovascular system. The function of Nox4, a member of the Nox family of NADPH... 
Aging | Oxidative stress | Reactive oxygen species | Superoxide | Apoptosis | Hypertrophy | CELLS | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | hypertrophy | PHOSPHORYLATION | apoptosis | ANGIOTENSIN-II | FAMILY NADPH OXIDASES | FREE-RADICALS | NAD(P)H OXIDASE | reactive oxygen species | PERIPHERAL VASCULAR DISEASE | GENERATION | aging | superoxide | HEMATOLOGY | oxidative stress | Aconitate Hydratase - metabolism | Up-Regulation | Cysteine | Cell Proliferation | Uncoupling Agents - pharmacology | Oxidative Stress | Rats, Wistar | Ventricular Function, Left | Apoptosis - drug effects | Mitochondria, Heart - pathology | Humans | NADPH Oxidases - metabolism | Cardiomegaly - pathology | Mitochondria, Heart - drug effects | Myocytes, Cardiac - enzymology | Transfection | Ventricular Dysfunction, Left - genetics | Rotenone - pharmacology | Superoxides - metabolism | Ventricular Dysfunction, Left - pathology | NADPH Oxidases - genetics | Ventricular Dysfunction, Left - enzymology | Disease Models, Animal | Oxidation-Reduction | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mitochondria, Heart - enzymology | Cardiomegaly - physiopathology | Rats | Genotype | Mice, Transgenic | Cardiomegaly - enzymology | NADPH Oxidase 4 | Onium Compounds - pharmacology | NADH Dehydrogenase - metabolism | Ventricular Dysfunction, Left - physiopathology | Aging - pathology | Myocytes, Cardiac - pathology | Phenotype | Animals | Myocytes, Cardiac - drug effects | Fibrosis | Mice | Cardiomegaly - genetics | Aging - metabolism
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 07/2014, Volume 307, Issue 2, pp. H252 - H258
Journal Article
Circulation Research, ISSN 0009-7330, 03/2008, Volume 102, Issue 6, pp. 703 - 710
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9572 - 9577
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2010, Volume 299, Issue 6, pp. H1891 - H1901
Sahan-Firat S, Jennings BL, Yaghini FA, Song CY, Estes AM, Fang XR, Farjana N, Khan AI, Malik KU. 2,3',4,5'-Tetramethoxystilbene prevents... 
Cytochrome P-450 1B1 activity | Endothelial dysfunction | Reactive oxygen species | Renal function | Vascular reactivity | ARACHIDONIC-ACID RELEASE | CYTOSOLIC PHOSPHOLIPASE A | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | SUPEROXIDE-PRODUCTION | NITRIC-OXIDE SYNTHASE | vascular reactivity | ANGIOTENSIN-II | endothelial dysfunction | VASCULAR SMOOTH-MUSCLE | II-INDUCED HYPERTENSION | cytochrome P-450 1B1 activity | reactive oxygen species | renal function | PERIPHERAL VASCULAR DISEASE | Antihypertensive Agents - pharmacology | Kidney - pathology | Kidney - enzymology | Endothelium, Vascular - drug effects | Male | Stilbenes - pharmacology | Proteinuria - prevention & control | Time Factors | p38 Mitogen-Activated Protein Kinases - metabolism | Hypertension - enzymology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Kidney - drug effects | Enzyme Inhibitors - pharmacology | Cardiomegaly - physiopathology | Rats | Cardiomegaly - enzymology | Sodium Chloride, Dietary | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Hypertension - pathology | Proteinuria - physiopathology | Cardiomegaly - prevention & control | Mitogen-Activated Protein Kinase 3 - metabolism | Cytochrome P-450 CYP1B1 | Vasodilation - drug effects | Muscle, Smooth, Vascular - enzymology | Mitogen-Activated Protein Kinase 1 - metabolism | Endothelium, Vascular - enzymology | Muscle, Smooth, Vascular - physiopathology | Hypertension - etiology | Superoxides - metabolism | Hypertension - prevention & control | Blood Pressure - drug effects | NADH, NADPH Oxidoreductases - metabolism | Aorta - enzymology | Kidney - physiopathology | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Aorta - drug effects | Desoxycorticosterone | Myocardium - pathology | Hypertension - physiopathology | NADPH Oxidase 1 | Aryl Hydrocarbon Hydroxylases - metabolism | Hydroxyeicosatetraenoic Acids - blood | Proteinuria - enzymology | Diuresis - drug effects | Myocardium - enzymology | Animals | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - blood | Hypertension | Prevention | Cytochrome P-450 | Physiological aspects | Development and progression | Health aspects
Journal Article
Circulation Research, ISSN 0009-7330, 03/2010, Volume 106, Issue 5, pp. 961 - 970
RATIONALE:Mitogen-activated protein kinase (MAPK) pathways provide a critical connection between extrinsic and intrinsic signals to cardiac hypertrophy.... 
Genetically modified mice | Cardiac hypertrophy | Signal transduction | TRANSCRIPTIONAL ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | signal transduction | DILATED CARDIOMYOPATHY | ENHANCER FACTOR-2 | BMK1/ERK5 | PATHWAY | genetically modified mice | CARDIAC-HYPERTROPHY | ENDOTHELIAL-CELLS | GROWTH | PERIPHERAL VASCULAR DISEASE | cardiac hypertrophy | HEMATOLOGY | EXPRESSION | TRANSGENIC MICE | Blood Pressure | Apoptosis - drug effects | Cardiomegaly - pathology | Male | Myocytes, Cardiac - enzymology | Transfection | RNA Interference | Time Factors | Mitogen-Activated Protein Kinase 7 - antagonists & inhibitors | Indoles - pharmacology | Transcription, Genetic | Hypertension - enzymology | Hypertension - genetics | Animals, Newborn | Aniline Compounds - pharmacology | Myogenic Regulatory Factors - genetics | Cells, Cultured | Cardiomegaly - physiopathology | Myogenic Regulatory Factors - metabolism | Rats | Mitogen-Activated Protein Kinase 7 - genetics | Cardiomegaly - enzymology | Hypertension - pathology | Hypertension - physiopathology | Mice, Knockout | Mitogen-Activated Protein Kinase 7 - deficiency | Myocytes, Cardiac - pathology | Animals | Cardiomegaly - prevention & control | Myocytes, Cardiac - drug effects | Fibrosis | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Cardiomegaly - genetics | Ventricular Remodeling - drug effects
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2010, Volume 49, Issue 2, pp. 210 - 220
Abstract Although increasing evidence indicates that an adipokine adiponectin exerts protective actions on heart, its effects on coronary angiogenesis... 
Cardiovascular | Heart failure | AMPK | Pressure overload | Cardiac angiogenesis | Adiponectin | ISCHEMIA-INDUCED ANGIOGENESIS | CARDIAC & CARDIOVASCULAR SYSTEMS | ACTIVATED PROTEIN-KINASE | REPERFUSION INJURY | HEART-FAILURE | CELL BIOLOGY | STIMULATES ANGIOGENESIS | SKELETAL-MUSCLE | HYPERTROPHY | ADIPOSE-SPECIFIC PROTEIN | ENDOTHELIAL GROWTH-FACTOR | OXIDATIVE/NITRATIVE STRESS | Vascular Endothelial Growth Factor A - biosynthesis | AMP-Activated Protein Kinases - metabolism | Capillaries - pathology | Constriction, Pathologic | Heart Failure - enzymology | Heart Failure - physiopathology | Capillaries - drug effects | Neovascularization, Pathologic - complications | Neovascularization, Pathologic - pathology | Myocytes, Cardiac - enzymology | Neovascularization, Pathologic - enzymology | Adiponectin - deficiency | Adiponectin - metabolism | Neovascularization, Pathologic - physiopathology | Phosphorylation - drug effects | Protein-Serine-Threonine Kinases - metabolism | Heart - physiopathology | Heart Failure - complications | Capillaries - physiopathology | AMP-Activated Protein Kinases - antagonists & inhibitors | Cells, Cultured | Cardiomegaly - physiopathology | Rats | Myocardium - pathology | Cardiomegaly - enzymology | Pressure | Cardiomegaly - complications | Myocytes, Cardiac - pathology | Myocardium - enzymology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Heart - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Ventricular Remodeling - drug effects | Universities and colleges | Cardiology | Vascular endothelial growth factor | adiponectin | heart failure | cardiac angiogenesis | pressure overload
Journal Article