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Circulation, ISSN 0009-7322, 10/2003, Volume 108, Issue 17, pp. 2147 - 2152
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6656
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective... 
METABOLISM | GENE | SIRT3-MEDIATED DEACETYLATION | PATHWAY | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | HOMOLOG | AKT | SIRTUINS | CALORIE RESTRICTION | CELL-DEATH | Mitochondria - enzymology | Fibroblasts - enzymology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Myofibroblasts - enzymology | Superoxide Dismutase - antagonists & inhibitors | Cardiomegaly - pathology | Isoproterenol | Lignans - pharmacology | Myocytes, Cardiac - enzymology | Phenylephrine - pharmacology | Biphenyl Compounds - pharmacology | Membrane Proteins - metabolism | Superoxide Dismutase - metabolism | Myofibroblasts - pathology | Sirtuin 3 - genetics | Signal Transduction | Membrane Proteins - genetics | Carrier Proteins - antagonists & inhibitors | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Myocardium - pathology | Cardiotonic Agents - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Fibroblasts - pathology | Myofibroblasts - drug effects | Adenosine Triphosphatases - antagonists & inhibitors | Carrier Proteins - genetics | Myocytes, Cardiac - pathology | Acetylation - drug effects | Myocardium - enzymology | Reactive Oxygen Species - antagonists & inhibitors | Animals | Cardiomegaly - prevention & control | Carrier Proteins - metabolism | Myocytes, Cardiac - drug effects | Membrane Proteins - antagonists & inhibitors | Cell Differentiation - drug effects | Fibroblasts - drug effects | Cardiomegaly - chemically induced | Adenosine Triphosphatases - genetics | Cell Proliferation - drug effects | Mice | Enzyme Activation | Primary Cell Culture | Cardiomegaly - genetics
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 09/2017, Volume 69, Issue 9, pp. 1191 - 1207
Objectives The aim of this study was to examine the cardioprotective effects and latent mechanism of tannic acid (TA) on cardiac hypertrophy. Methods Abdominal... 
endothelin | tannic acid | cardiac hypertrophy | pressure overload | oxidative stress | MYOCARDIAL-INFARCTION | ENDOTHELIAL DYSFUNCTION | HEART-FAILURE | FRENCH PARADOX | LEFT-VENTRICULAR HYPERTROPHY | INDUCED HYPERTENSION | RENIN-ANGIOTENSIN SYSTEM | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | II TYPE-2 RECEPTOR | Captopril - pharmacology | Rats, Wistar | Apoptosis - drug effects | Endothelin-1 - metabolism | Cardiomegaly - physiopathology | Rats | Male | Tannins - administration & dosage | Cardiotonic Agents - pharmacology | Down-Regulation - drug effects | Receptors, Angiotensin - genetics | Dose-Response Relationship, Drug | Animals | Cardiomegaly - prevention & control | Cardiotonic Agents - administration & dosage | Tannins - pharmacology | Inflammation - prevention & control | Oxidative Stress - drug effects | Fibrosis - prevention & control | Nitric Oxide - metabolism | Disease Models, Animal | Heart | Endothelin | Interleukins | RNA | Heart enlargement | Nitric oxide | Physiological aspects | Bone morphogenetic proteins | Superoxide | Transforming growth factors | Endothelium | Tannic acid | Oxidative stress | Phosphorylation | Matrix metalloproteinases | Bax protein | Bcl-2 protein | Proteinase | Interleukin | Superoxide dismutase | mRNA | Caspase-3 | Angiotensin receptors | Receptors | Catalase | Angiotensin AT1 receptors | Interleukin 1 | Tumor necrosis factor-TNF | Aorta | Peroxidase | Heart diseases | Glutathione | Extracellular signal-regulated kinase | Caspase | Endothelin 1 | Gene expression | Pressure | Malondialdehyde | Gelatinase B | Banding | Acids | Fibrosis | Angiotensin AT2 receptors | Tumors | Apoptosis
Journal Article
AJP - Heart and Circulatory Physiology, ISSN 0363-6135, 03/2008, Volume 294, Issue 3, pp. H1398 - H1406
Journal Article
Translational Research, ISSN 1931-5244, 2016, Volume 172, pp. 96 - 112.e6
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 11/2016, Volume 37, pp. 13 - 19
Aldosterone plays a central role in the development of cardiac pathological states involving ion transport imbalances, especially sodium transport. We have... 
Mineralocorticoid receptor | Cardiac hypertrophy | ENaC | Aldosterone | SGK1 | Nedd4-2 | Proanthocyanidins | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | CARDIOVASCULAR-SYSTEM | SERUM | EPITHELIAL SODIUM-CHANNEL | NUTRITION & DIETETICS | NA+ CHANNEL | GLUCOCORTICOID-INDUCIBLE KINASE | GRAPE-SEED PROANTHOCYANIDINS | RENAL INJURY | Epithelial Sodium Channel Agonists - metabolism | Oxidative Stress | Rats, Wistar | Cardiomegaly - etiology | Ubiquitin-Protein Ligases - antagonists & inhibitors | Heart Ventricles - immunology | Male | Epithelial Sodium Channels - metabolism | Epithelial Sodium Channel Agonists - antagonists & inhibitors | Hypertension - etiology | Cardiotonic Agents - therapeutic use | Immediate-Early Proteins - metabolism | Immediate-Early Proteins - agonists | Endosomal Sorting Complexes Required for Transport - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Ventricular Dysfunction, Left - pathology | Hypertension - prevention & control | Nedd4 Ubiquitin Protein Ligases | Heart Ventricles - pathology | Protein-Serine-Threonine Kinases - metabolism | Biomarkers - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin-Protein Ligases - metabolism | Proanthocyanidins - therapeutic use | Antihypertensive Agents - therapeutic use | Epithelial Sodium Channels - chemistry | Ventricular Dysfunction, Left - physiopathology | Ventricular Dysfunction, Left - prevention & control | Mineralocorticoid Receptor Antagonists - therapeutic use | Ventricular Dysfunction, Left - metabolism | Antioxidants - therapeutic use | Animals | Cardiomegaly - prevention & control | Heart Ventricles - physiopathology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Epithelial Sodium Channel Blockers - therapeutic use | Fibrosis | Endosomal Sorting Complexes Required for Transport - agonists | Heart Ventricles - metabolism | Dietary Supplements | Immediate-Early Proteins - antagonists & inhibitors | Corticosteroids | Steroids
Journal Article
Journal of Hypertension, ISSN 0263-6352, 04/2015, Volume 33, Issue 4, pp. 843 - 850
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 11/2016, Volume 192, pp. 170 - 177
(Burm. f.) Nees (Acanthaceae) has a considerable medicinal reputation in most parts of Asia as a potent medicine in the treatment of Endocrine disorders,... 
Obesity | Andrographis paniculata | Cardiac remodeling | Cardiomyopathy | CHEMISTRY, MEDICINAL | OBESE ZUCKER RATS | HEART-FAILURE | DIABETIC-RATS | PROTECTS | PLANT SCIENCES | VENTRICULAR HYPERTROPHY | INHIBITION | PATHWAY | INTEGRATIVE & COMPLEMENTARY MEDICINE | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | MEDICINAL-PLANTS | Receptor, IGF Type 1 - metabolism | Obesity - drug therapy | Apoptosis - drug effects | Plant Extracts - pharmacology | Solvents - chemistry | Cardiomegaly - etiology | Cardiomegaly - pathology | Diet, High-Fat | Inflammation Mediators - metabolism | Water - chemistry | Anti-Inflammatory Agents - isolation & purification | Phytotherapy | Disease Models, Animal | Anti-Inflammatory Agents - pharmacology | Obesity - complications | Mice, Inbred C57BL | Plant Extracts - isolation & purification | Andrographis - chemistry | Cardiovascular Agents - pharmacology | Obesity - metabolism | Collagen - metabolism | Myocytes, Cardiac - pathology | Animals | Cardiomegaly - prevention & control | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Cardiovascular Agents - isolation & purification | Cyclooxygenase 2 - metabolism | Myocytes, Cardiac - metabolism | Plants, Medicinal | Cardiomegaly - metabolism | Heart | Medical colleges | Armed Forces | Heart enlargement | Emergency medicine | Cardiology | Apoptosis | Prevention | Cardiac patients
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 33, pp. 17427 - 17436
Journal Article