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Trends in Molecular Medicine, ISSN 1471-4914, 2012, Volume 18, Issue 6, pp. 337 - 347
Glucosinolates and isothiocyanates have both been objects of research for more than half a century. Interest in these unique phytochemicals escalated following... 
Pathology | PHENETHYL ISOTHIOCYANATE | MEDICINE, RESEARCH & EXPERIMENTAL | MIGRATION INHIBITORY FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | BENZYL ISOTHIOCYANATE | CRUCIFEROUS VEGETABLES | SULFORAPHANE RESTORES | CELL BIOLOGY | TRANSCRIPTION FACTOR NRF2 | TRAUMATIC BRAIN-INJURY | INTRACEREBRAL HEMORRHAGE | SPINAL-CORD-INJURY | BROCCOLI SPROUT BEVERAGES | Cardiovascular Diseases - drug therapy | Humans | Isothiocyanates - administration & dosage | Diabetic Nephropathies - drug therapy | Glucosinolates - chemistry | Neuroprotective Agents - pharmacology | Anticarcinogenic Agents - administration & dosage | Isothiocyanates - chemistry | Anti-Bacterial Agents - chemistry | Helicobacter Infections - drug therapy | Models, Animal | Neuroprotective Agents - administration & dosage | Anticarcinogenic Agents - pharmacology | Isothiocyanates - pharmacology | Neuroprotective Agents - chemistry | Cardiotonic Agents - chemistry | Cardiotonic Agents - pharmacology | Animals | Anticarcinogenic Agents - chemistry | Cardiotonic Agents - administration & dosage | Glucosinolates - pharmacology | Central Nervous System - drug effects | Anti-Bacterial Agents - pharmacology | Cell Transformation, Neoplastic - drug effects | Anti-Bacterial Agents - administration & dosage | Glucosinolates - administration & dosage | Skin - drug effects | Proteins | Analysis
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 03/2013, Volume 18, Issue 8, pp. 899 - 929
Significance: Anthracyclines (doxorubicin, daunorubicin, or epirubicin) rank among the most effective anticancer drugs, but their clinical usefulness is... 
Forum Review Articles | DOXORUBICIN-INDUCED CARDIOTOXICITY | ADVANCED BREAST-CANCER | SPONTANEOUSLY HYPERTENSIVE-RATS | MANGANESE SUPEROXIDE-DISMUTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADRIAMYCIN-INDUCED CARDIOMYOPATHY | ACUTE LYMPHOBLASTIC-LEUKEMIA | ENDOCRINOLOGY & METABOLISM | SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE | MITOCHONDRIAL CALCIUM HOMEOSTASIS | CONGESTIVE-HEART-FAILURE | FREE-RADICAL FORMATION | Anthracyclines - adverse effects | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Oxidative Stress | Humans | Metals - adverse effects | Razoxane - pharmacology | Anthracyclines - pharmacology | Antineoplastic Agents - adverse effects | Cardiotonic Agents - adverse effects | Myocardium - metabolism | Antineoplastic Agents - pharmacology | Razoxane - chemistry | Chelating Agents - adverse effects | Anthracyclines - chemistry | Oxidation-Reduction | Signal Transduction | Chelating Agents - chemistry | Cardiotonic Agents - chemistry | Antioxidants - pharmacology | Cardiotonic Agents - pharmacology | Chelating Agents - pharmacology | Antineoplastic Agents - chemistry | Razoxane - adverse effects | Heart - drug effects | Complications and side effects | Oxidative stress | Anthracyclines | Oxidation-reduction reaction | Chemical reactions | Dosage and administration | Research | Index Medicus | Forum Review
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2016, Volume 106, pp. 1 - 18
Bromodomains are epigenetic readers of histone acetylation involved in chromatin remodeling and transcriptional regulation. The human proteome comprises 46... 
BET proteins | Acetylated histones | Drug discovery | Epigenetic drugs | Bromodomains | SELECTIVE-INHIBITION | EPIGENETIC READERS | TRANSCRIPTIONAL ACTIVITY | DISPLACEMENT ASSAYS | SYNERGISTIC ACTIVITY | FRAGMENT-BASED DISCOVERY | SMALL-MOLECULE INHIBITORS | CBP/P300 BROMODOMAIN | CHEMICAL PROBE | PHARMACOLOGY & PHARMACY | Chromatin - metabolism | Transcription, Genetic - drug effects | Transcription Factors - chemistry | Histones - chemistry | Triazoles - chemistry | Cardiovascular Diseases - drug therapy | Humans | Cardiovascular Diseases - pathology | Cardiovascular Diseases - genetics | Autoimmune Diseases - genetics | Azepines - chemistry | Neoplasms - genetics | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Acetylation | Autoimmune Diseases - pathology | Chromatin - drug effects | Histones - antagonists & inhibitors | Autoimmune Diseases - drug therapy | Chromatin - chemistry | Benzodiazepines - pharmacology | Chromatin Assembly and Disassembly | Models, Molecular | Transcription Factors - antagonists & inhibitors | Cardiotonic Agents - chemistry | Cardiotonic Agents - pharmacology | Transcription Factors - genetics | Antineoplastic Agents - chemistry | Drug Discovery | Neoplasms - drug therapy | Azepines - pharmacology | Triazoles - pharmacology | Histones - genetics | Benzodiazepines - chemistry | Neoplasms - pathology | Irritable bowel syndrome | Life Sciences | Biochemistry, Molecular Biology | Biomolecules
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 04/2008, Volume 8, Issue 4, pp. 399 - 420
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2007, Volume 129, Issue 9, pp. 2482 - 2487
Journal Article
Pharmacological Research, ISSN 1043-6618, 05/2017, Volume 119, pp. 373 - 383
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-known bioactive compound derived from the active ingredient of turmeric... 
Oxidative stress | Myocardial ischemia | Curcumin | Histone acetylation | Cardiac diseases | KAPPA-B ACTIVATION | DOWN-REGULATION | SIRT1 ACTIVATION | INDUCED MYOCARDIAL-INFARCTION | ISCHEMIA-REPERFUSION INJURY | BRUGADA-SYNDROME | PHARMACOLOGY & PHARMACY | INFLAMMATORY RESPONSE | UP-REGULATION | PREVENTS DIABETIC CARDIOMYOPATHY | Inflammation - pathology | Myocardium - immunology | Antioxidants - chemistry | Heart Diseases - metabolism | Curcumin - chemistry | Heart - embryology | Humans | Cardiotonic Agents - therapeutic use | Inflammation - metabolism | Inflammation - drug therapy | Myocardium - metabolism | Anti-Inflammatory Agents - therapeutic use | Curcumin - therapeutic use | Anti-Inflammatory Agents - pharmacology | Curcumin - pharmacology | Myocardium - pathology | Cardiotonic Agents - chemistry | Inflammation - immunology | Antioxidants - pharmacology | Cardiotonic Agents - pharmacology | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents - chemistry | Heart - drug effects | Heart Diseases - drug therapy | Oxidative Stress - drug effects | Heart Diseases - pathology | Curcuma - chemistry | Heart Diseases - immunology | Cardiovascular diseases | Medical colleges | Biomedical engineering | Embryonic development | Arrhythmia | Developmental biology | Analysis | Interferon | Biological response modifiers | Coxsackievirus infections
Journal Article