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European Journal of Cancer, ISSN 0959-8049, 05/2016, Volume 58, pp. 112 - 121
Journal Article
2010, ISBN 0470772743, xvi, 342
Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the... 
Cardiovascular toxicology
Book
Journal Article
Circulation, ISSN 0009-7322, 2013, Volume 128, Issue 17, pp. 1927 - 1995
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 03/2016, Volume 225, pp. 170 - 182
Hyaluronic acid (HA)-based doxorubicin (DOX) nanoparticles (HA-NPs) were fabricated ion-pairing between positively charged DOX and negatively charged HA, which... 
Liposome | Ion-pairing | Nanoparticle | Hyaluronic acid (HA) | Doxorubicin (DOX) | CELLS | DRUG-DELIVERY | DOXORUBICIN | NANOCARRIERS | CARDIOTOXICITY | CANCER | CHEMISTRY, MULTIDISCIPLINARY | IN-VIVO | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | MULTIDRUG-RESISTANCE | CD44 | Neoplasms - metabolism | Hyaluronic Acid - therapeutic use | Drug Carriers - therapeutic use | Nanoparticles - chemistry | Rats, Wistar | Humans | Drug Carriers - administration & dosage | Delayed-Action Preparations - chemistry | Male | Doxorubicin - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Antibiotics, Antineoplastic - chemistry | Nanoparticles - therapeutic use | Delayed-Action Preparations - pharmacokinetics | Doxorubicin - analogs & derivatives | Hyaluronan Receptors - metabolism | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Hyaluronic Acid - chemistry | Hyaluronic Acid - pharmacokinetics | Doxorubicin - pharmacokinetics | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Animals | Antibiotics, Antineoplastic - therapeutic use | Tumor Burden - drug effects | Cell Line, Tumor | Delayed-Action Preparations - therapeutic use | Drug Liberation | Drug Carriers - pharmacokinetics | Mice | Nanoparticles - administration & dosage | Neoplasms - pathology | Nanoparticles | Hyaluronic acid | Tumors | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2016, Volume 22, Issue 5, pp. 547 - 556
Doxorubicin is an anthracycline chemotherapy agent effective in treating a wide range of malignancies, but it causes a dose-related cardiotoxicity that can... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | RISK-FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEXRAZOXANE | INDUCED CARDIOMYOPATHY | MATURATION | MUSCLE GENE-EXPRESSION | CELL BIOLOGY | CHILDHOOD-CANCER | INHIBITION | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | CONGESTIVE-HEART-FAILURE | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Calcium - metabolism | Humans | Middle Aged | Transcriptome | Antibiotics, Antineoplastic - adverse effects | Mitochondria, Heart - drug effects | Membrane Potential, Mitochondrial - drug effects | Flow Cytometry | Adult | Female | Real-Time Polymerase Chain Reaction | Cardiotoxicity - genetics | DNA Damage - drug effects | Cell Survival - drug effects | Disease Susceptibility | Heart Failure - genetics | Breast Neoplasms - drug therapy | Myocytes, Cardiac - drug effects | Fluorescent Antibody Technique | Myocytes, Cardiac - metabolism | Aged | Polymorphism, Single Nucleotide | Oxidative Stress - drug effects | Induced Pluripotent Stem Cells | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Heart Failure - chemically induced | Complications and side effects | Patient outcomes | Stem cells | Development and progression | Breast cancer | Transplantation | Cardiovascular diseases | Drug therapy | Doxorubicin | Methods | Heart failure | Chemotherapy | Toxicity | Index Medicus
Journal Article
Aging, ISSN 1945-4589, 12/2009, Volume 1, Issue 12, pp. 988 - 1007
Short-term fasting ( 48 hours) was shown to be effective in protecting normal cells and mice but not cancer cells against high dose chemotherapy, termed... 
LIFE-SPAN | IGF-I | OXIDATIVE STRESS | Toxicity | CARDIOTOXICITY | fasting | DIETARY RESTRICTION | CELL BIOLOGY | INSULIN | Side-effect | Chemotherapy | GROWTH | RESISTANCE | NUTRITION | Cancer | CALORIE RESTRICTION | NEPHROTOXICITY | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2012, Volume 30, Issue 31, pp. 3792 - 3799
Journal Article
Journal Article