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Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 6, pp. 991 - 1006
Excess weight gain, especially when associated with increased visceral adiposity, is a major cause of hypertension, accounting for 65% to 75% of the risk for... 
blood pressure | kidney | chronic renal insufficiency | melanocortins | leptin | mineralocorticoids | CARDIAC & CARDIOVASCULAR SYSTEMS | SYMPATHETIC-NERVOUS-SYSTEM | NATRIURETIC PEPTIDES | CARDIOVASCULAR FUNCTIONS | BLOOD-PRESSURE | MELANOCORTIN SYSTEM | BODY-MASS-INDEX | RENIN-ANGIOTENSIN SYSTEM | ARTERIAL-PRESSURE | SELECTIVE LEPTIN RESISTANCE | PERIPHERAL VASCULAR DISEASE | CHRONIC KIDNEY-DISEASE | HEMATOLOGY | Natriuresis - physiology | Antihypertensive Agents - pharmacology | Intra-Abdominal Fat - physiopathology | Prevalence | Dyslipidemias - complications | Humans | Sodium - metabolism | Sympathetic Nervous System - physiopathology | Pro-Opiomelanocortin - physiology | Hypertension - etiology | Leptin - physiology | Insulin Resistance - physiology | Metabolic Syndrome - physiopathology | Models, Animal | Parasympathetic Nervous System - physiopathology | Hypertension - epidemiology | Kidney - physiopathology | Models, Cardiovascular | Obesity - complications | Aldosterone - physiology | Obesity - physiopathology | Renin-Angiotensin System - physiology | Antihypertensive Agents - therapeutic use | Organ Specificity | Pressure | Renal Insufficiency, Chronic - physiopathology | Hypertension - physiopathology | Metabolic Syndrome - complications | Animals | Heart Conduction System - physiopathology | Receptors, Leptin - physiology | Obesity - epidemiology | Renin-Angiotensin System - drug effects | Hemodynamics | Dyslipidemias - physiopathology | chronic kidney disease | sympathetic activity | Blood pressure | renin-angiotensin system
Journal Article
Circulation Research, ISSN 0009-7330, 03/2014, Volume 114, Issue 6, pp. 1004 - 1021
Journal Article
Circulation, ISSN 0009-7322, 07/2007, Volume 116, Issue 1, pp. 77 - 84
NERVOUS-SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | antioxidants | SUDDEN-DEATH | nervous system, autonomic | INJURY | apoptosis | death, sudden | nervous system, sympathetic | INTRACRANIAL HEMORRHAGE | DAMAGE | MYOCARDIAL LESIONS | cerebral infarction | INSULAR CORTEX | SUBARACHNOID HEMORRHAGE | PERIPHERAL VASCULAR DISEASE | cardiomyopathy | STRESS | Thyroxine - toxicity | Calcium - metabolism | Humans | Death, Sudden, Cardiac - etiology | Sympathetic Nervous System - physiopathology | Fludrocortisone - analogs & derivatives | Arrhythmias, Cardiac - physiopathology | Necrosis | Cardiotonic Agents - therapeutic use | Stress, Physiological - complications | Fludrocortisone - toxicity | Electrocardiography | Myocardial Stunning - etiology | Parasympathetic Nervous System - physiopathology | Heart Diseases - chemically induced | Culture | Helplessness, Learned | Ergocalciferols - toxicity | Cats | Psychophysiologic Disorders - physiopathology | Myocardial Stunning - physiopathology | Heart Diseases - physiopathology | Myocardial Stunning - psychology | Rats | Catecholamines - physiology | Myocardium - pathology | Stress, Physiological - physiopathology | Arrhythmias, Cardiac - etiology | Catecholamines - toxicity | Immobilization - adverse effects | Subarachnoid Hemorrhage - complications | Hypothalamus - physiopathology | Emotions | Myocardial Reperfusion Injury - physiopathology | Vagus Nerve - physiopathology | Catecholamines - antagonists & inhibitors | Heart Diseases - etiology | Heart Diseases - psychology | Subarachnoid Hemorrhage - physiopathology | Animals | Psychophysiologic Disorders - psychology | Heart Conduction System - physiopathology | Dogs | Mice | Stress, Physiological - psychology | Heart | Physiological aspects | Brain | Research
Journal Article
Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 6, pp. 976 - 990
Several articles have dealt with the importance and mechanisms of the sympathetic nervous system alterations in experimental animal models of hypertension.... 
hypertension essential | renal insufficiency | sympathetic nervous system | CARDIAC & CARDIOVASCULAR SYSTEMS | RESISTANT HYPERTENSION | PLASMA NOREPINEPHRINE | BLOOD-PRESSURE | RENAL DENERVATION | SKELETAL-MUSCLE | OBESITY-INDUCED HYPERTENSION | NEURAL ACTIVATION | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | REFLEX ABNORMALITIES | HEMATOLOGY | BAROREFLEX CONTROL | Kidney Diseases - physiopathology | Neuroimaging | Antihypertensive Agents - pharmacology | Humans | Hypertension - drug therapy | Hypertension, Renal - physiopathology | Sympathetic Nervous System - physiopathology | Hypertension - etiology | Melanocortins - physiology | Leptin - physiology | Vasoconstriction - physiology | Multicenter Studies as Topic | Insulin Resistance - physiology | Sympathectomy - methods | Metabolic Syndrome - physiopathology | Heart Rate - physiology | Kidney Diseases - complications | Hypertension - therapy | Hypertension, Renal - surgery | Hyperinsulinism - physiopathology | Obesity - complications | Diagnostic Techniques, Cardiovascular | Obesity - physiopathology | Clinical Trials as Topic | Sympathetic Fibers, Postganglionic - physiology | Antihypertensive Agents - therapeutic use | Forecasting | Hypertension - physiopathology | Metabolic Syndrome - complications | Norepinephrine - blood | Animals | Kidney - innervation | Leptin - deficiency | essential hypertension | renal failure | human obesity | renal denervation
Journal Article
Circulation Research, ISSN 0009-7330, 06/2015, Volume 116, Issue 12, pp. 2005 - 2019
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates nearly all physiological functions of the heart (chronotropy,... 
arrhythmias, cardiac | physiopathology | autonomic nervous system | death, sudden cardiac | POLYMORPHIC VENTRICULAR-TACHYCARDIA | CARDIAC & CARDIOVASCULAR SYSTEMS | death | SPINAL-CORD | sudden cardiac | ATRIAL-FIBRILLATION | RENAL SYMPATHETIC DENERVATION | arrhythmias | HEART-RATE-VARIABILITY | ACUTE MYOCARDIAL-INFARCTION | PERIPHERAL VASCULAR DISEASE | GROWTH-FACTOR | TREATMENT-RESISTANT HYPERTENSION | HEMATOLOGY | T-WAVE ALTERNANS | cardiac | AUTONOMIC NERVOUS-SYSTEM | Humans | Myocardial Contraction - physiology | Afferent Pathways - physiopathology | Death, Sudden, Cardiac - etiology | Hypertension, Renal - physiopathology | Autonomic Nervous System - physiopathology | Arrhythmias, Cardiac - physiopathology | Nerve Growth Factor - physiology | Heart Diseases - complications | Cell Transdifferentiation | Hypertension, Renal - surgery | Diabetic Neuropathies - physiopathology | Disease Models, Animal | Heart - innervation | Autonomic Nervous System Diseases - complications | Heart Diseases - physiopathology | Translational Medical Research | Nerve Regeneration | Feedback, Physiological | Animals | Autonomic Nervous System Diseases - physiopathology | Heart Conduction System - physiopathology | Semaphorin-3A - physiology | Kidney - innervation | Mice | Hemodynamics | Denervation | sudden cardiac death | Autonomic nervous system | arrhythmia | pathophysiology
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 07/2012, Volume 1261, Issue 1, pp. 55 - 63
Enhanced susceptibility to inflammatory and autoimmune disease can be related to impairments in HPA axis activity and associated hypocortisolism, or to... 
psychoneuroimmunology | stress | cortisol | cytokines | depression | autoimmune | Depression | Autoimmune | Cortisol | Psychoneuroimmunology | Cytokines | Stress | CORTICOTROPIN-RELEASING HORMONE | PSYCHOLOGICAL STRESS | DNA-BINDING | METABOLIC SYNDROME | MULTIDISCIPLINARY SCIENCES | BETA-ISOFORM | IMMUNE | SWEAT PATCHES | GENE-EXPRESSION | CENTRAL-NERVOUS-SYSTEM | PITUITARY-ADRENAL AXIS | Depression - physiopathology | Cushing Syndrome - physiopathology | Humans | Neuroimmunomodulation - physiology | Receptors, Glucocorticoid - metabolism | Cushing Syndrome - metabolism | Depression - genetics | Glucocorticoids - immunology | Depression - metabolism | Inflammation - metabolism | Metabolic Diseases - physiopathology | Osteoporosis - metabolism | Glucocorticoids - metabolism | Stress, Psychological - metabolism | Corticosterone - immunology | Hypothalamo-Hypophyseal System - physiopathology | Osteoporosis - physiopathology | Cardiovascular Diseases - physiopathology | Pituitary-Adrenal System - physiopathology | Cardiovascular Diseases - metabolism | Pituitary-Adrenal System - metabolism | Receptors, Glucocorticoid - immunology | Hypothalamo-Hypophyseal System - metabolism | Stress, Psychological - genetics | Animals | Receptors, Glucocorticoid - genetics | Biomarkers | Inflammation - genetics | Corticosterone - metabolism | Mice | Inflammation - physiopathology | Stress, Psychological - physiopathology | Genes | Receptors | Control | Illnesses | Glucocorticoids | Impairment | Genetics | Management
Journal Article
Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 6, pp. 937 - 959
Until recently, significant advances in our understanding of the mechanisms of blood pressure regulation arose from studies of monogenic forms of hypertension... 
blood pressure | uromodulin | exome | hypertension | natriuretic peptide, brain | genome-wide association study | COMMON VARIANTS | ALDOSTERONE-PRODUCING ADENOMAS | CARDIAC & CARDIOVASCULAR SYSTEMS | KELCH-LIKE 3 | SECONDARY HYPERTENSION | SOMATIC MUTATIONS | MINERALOCORTICOID RECEPTOR | NATRIURETIC-PEPTIDE | MISSING HERITABILITY | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AMBULATORY BLOOD-PRESSURE | GENOME-WIDE ASSOCIATION | Kidney Diseases - physiopathology | Paraganglioma - physiopathology | Oligonucleotide Array Sequence Analysis | Sodium, Dietary - adverse effects | Blood Pressure - genetics | Humans | Hypertension - drug therapy | Male | Sympathetic Nervous System - physiopathology | Hypotension - genetics | Kidney Diseases - genetics | Pheochromocytoma - physiopathology | Hypertension, Pregnancy-Induced - genetics | Bartter Syndrome - genetics | Hyperaldosteronism - physiopathology | Glucocorticoids - physiology | Female | Blood Pressure - physiology | Neoplastic Syndromes, Hereditary - genetics | Hypertension - genetics | Mineralocorticoids - physiology | Genetic Predisposition to Disease | Genome-Wide Association Study | Models, Cardiovascular | Paraganglioma - genetics | Hyperaldosteronism - genetics | Hypertension, Pregnancy-Induced - physiopathology | Renin-Angiotensin System - genetics | Renin-Angiotensin System - physiology | Hypertension - physiopathology | Pregnancy | Adrenal Gland Neoplasms - physiopathology | Sodium, Dietary - pharmacokinetics | Neoplastic Syndromes, Hereditary - physiopathology | Pheochromocytoma - genetics | Bartter Syndrome - physiopathology | Polymorphism, Single Nucleotide | Mutation | Adrenal Gland Neoplasms - genetics
Journal Article
Sleep Medicine Reviews, ISSN 1087-0792, 2008, Volume 12, Issue 3, pp. 197 - 210
Summary Frequently disrupted and restricted sleep is a common problem for many people in our modern around-the-clock society. In this context, it is an... 
Neurology | Sleep Medicine | Sleep disturbance | Serotonin | Depression | Cardiovascular disease | Hypothalamic-pituitary-adrenal axis | Sleep restriction | Sympathetic nervous system | Corticotropin-releasing hormone | Sleep deprivation | Stress | stress | cardiovascular disease | hypothalamic-pituitary-adrenal axis | NERVOUS-SYSTEM | corticotropin-releasing hormone | sleep disturbance | sleep restriction | sympathetic nervous system | CIRCADIAN-RHYTHMS | NEUROSCIENCES | BLOOD-PRESSURE | CLINICAL NEUROLOGY | HYPOCRETIN OREXIN | COERULEUS-NORADRENERGIC SYSTEM | sleep deprivation | serotonin | CORTICOTROPIN-RELEASING-FACTOR | CLINICAL-IMPLICATIONS | CORTISOL SECRETION | depression | RAT-BRAIN | PITUITARY-ADRENAL AXIS | Adaptation, Psychological - physiology | Receptors, Serotonin - physiology | Pituitary-Adrenal System - physiopathology | Sleep Disorders, Circadian Rhythm - psychology | Sleep Disorders, Circadian Rhythm - diagnosis | Sleep Initiation and Maintenance Disorders - diagnosis | Brain - physiopathology | Humans | Stress Disorders, Post-Traumatic - psychology | Stress Disorders, Post-Traumatic - physiopathology | Sympathetic Nervous System - physiopathology | Autonomic Nervous System - physiopathology | Sleep Deprivation - diagnosis | Arousal - physiology | Sleep Deprivation - physiopathology | Animals | Neurosecretory Systems - physiology | Stress Disorders, Post-Traumatic - diagnosis | Sleep Deprivation - psychology | Sleep Disorders, Circadian Rhythm - physiopathology | Sleep Initiation and Maintenance Disorders - physiopathology | Hypothalamo-Hypophyseal System - physiopathology | Sleep Initiation and Maintenance Disorders - psychology | Corticotropin releasing hormone | Hypothalamic hormones | Sleep | Index Medicus
Journal Article
Psychoneuroendocrinology, ISSN 0306-4530, 2012, Volume 38, Issue 1, pp. 1 - 11
Summary Low birthweight, a marker of an adverse in utero environment, is associated with cardiometabolic disease and brain disorders in adulthood. The adaptive... 
Endocrinology & Metabolism | Psychiatry | Cognitive decline | Programming | Glucocorticoids | Metabolic syndrome | Hypothalamic–pituitary–adrenal axis | Birthweight | Hypothalamic-pituitary-adrenal axis | Adaptation, Physiological | Metabolic Syndrome - etiology | Prenatal Exposure Delayed Effects | Cushing Syndrome - physiopathology | Humans | Brain Diseases, Metabolic - embryology | Fetus - physiology | Cognition Disorders - etiology | Metabolic Syndrome - physiopathology | Glucocorticoids - physiology | Adult | Female | Metabolic Syndrome - embryology | Neuropsychology | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - antagonists & inhibitors | Hypothalamo-Hypophyseal System - physiopathology | Glucocorticoids - adverse effects | Infant, Newborn | Stress, Physiological - physiology | Cardiovascular Diseases - etiology | Developmental Disabilities - physiopathology | Infant, Low Birth Weight | Cardiovascular Diseases - physiopathology | Cognition Disorders - physiopathology | Pituitary-Adrenal System - physiopathology | Neuroendocrinology | Maternal-Fetal Exchange | Developmental Disabilities - etiology | Awards and Prizes | Placenta - enzymology | Pregnancy Complications - physiopathology | Pregnancy | Pregnancy Complications - psychology | Cushing Syndrome - psychology | Feedback, Physiological | Animals | Brain Diseases, Metabolic - physiopathology | Models, Biological | Cushing Syndrome - embryology | Brain Diseases, Metabolic - etiology | Infant, Small for Gestational Age | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - physiology | Cardiovascular Diseases - embryology | Stress, Psychological - physiopathology | Hypertension | Enzymes | Corticosteroids | Biological products | Growth | Genes | Diagnostic imaging | Risk factors | Physiological aspects | Medical tests | Fetus | Methylation | Steroids
Journal Article