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Journal of the American College of Cardiology, ISSN 0735-1097, 03/2017, Volume 69, Issue 10, pp. 1288 - 1304
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 09/2010, Volume 9, Issue 17, pp. 3515 - 3533
Recently, using a co-culture system, we demonstrated that MCF7 epithelial cancer cells induce oxidative stress in adjacent cancer-associated fibroblasts,... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Caveolin-1 | Oxidative stress | TIGAR | NFκB | BNIP3 | Tumor stroma | Cancer associated fibroblasts | Mitophagy | Autophagy | HIF1 | Hypoxia | LC3 | Predictive biomarker | hypoxia | autophagy | ONCOGENICALLY TRANSFORMED-CELLS | NITRIC-OXIDE SYNTHASE | DOWN-REGULATION | INDUCIBLE FACTOR INDUCTION | cancer associated fibroblasts | CELL BIOLOGY | BREAST-CANCER | caveolin-1 | mitophagy | predictive biomarker | tumor stroma | CAROTID-BODY | EXPRESSION | NF kappa B | oxidative stress | MITOCHONDRIAL COMPLEX-III | Up-Regulation | Oxidative Stress | Microtubule-Associated Proteins - metabolism | Coculture Techniques | Humans | Tumor Microenvironment | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Breast Neoplasms - metabolism | Cell Hypoxia | Chloroquine - pharmacology | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Female | Glutathione Synthase - metabolism | Membrane Proteins - metabolism | Antirheumatic Agents - pharmacology | Glutathione Synthase - antagonists & inhibitors | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Paracrine Communication | Cell Survival | Stromal Cells - metabolism | Caveolin 1 - genetics | Mice, Knockout | Caveolin 1 - metabolism | Animals | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | RNA, Small Interfering - metabolism | Report | cancer-associated fibroblasts
Journal Article
Steroids, ISSN 0039-128X, 05/2015, Volume 97, pp. 2 - 7
The skin irritating principle from was isolated, named thapsigargin and the structure elucidated. By inhibiting the sarco/endoplasmic reticulum Ca ATPase... 
Thapsigargin | Prodrug | Sarco/endoplasmic reticulum (SERCA) | Targeting drugs | Prostate specific antigen (PSA) | Prostate specific membrane antigen (PSMA) | ANALOGS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SARCOPLASMIC-RETICULUM | TRILOBOLIDE | CA2+-ATPASE | PROSTATE-CANCER CELLS | CALCIUM | ENDOCRINOLOGY & METABOLISM | BINDING-SITE | LIBERATING SESQUITERPENE LACTONES | THAPSIA-GARGANICA L | Apoptosis - drug effects | Humans | Soft Tissue Neoplasms - drug therapy | Male | Prodrugs - isolation & purification | Prodrugs - chemistry | Neovascularization, Pathologic - pathology | Enzyme Inhibitors - chemistry | Sarcoplasmic Reticulum Calcium-Transporting ATPases - antagonists & inhibitors | Apiaceae - chemistry | Molecular Structure | Prostatic Neoplasms - drug therapy | Thapsigargin - chemistry | Prostatic Neoplasms - pathology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Enzyme Inhibitors - pharmacology | Antineoplastic Agents, Phytogenic - chemistry | Enzyme Inhibitors - isolation & purification | Thapsigargin - isolation & purification | Animals | Neovascularization, Pathologic - drug therapy | Soft Tissue Neoplasms - pathology | Thapsigargin - pharmacology | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Prodrugs - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Tumors | endoplasmic reticulum (SERCA) | Sarco
Journal Article
eBook
Heart, ISSN 1355-6037, 08/2016, Volume 102, Issue 15, pp. 1230 - 1245
Journal Article