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Nature medicine, ISSN 1546-170X, 2012, Volume 18, Issue 7, pp. 1148 - 1153
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2007, Volume 98, Issue 3, pp. 614 - 620
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 2008, Volume 294, Issue 6, pp. H2721 - H2735
...), prolongs life span in evolutionarily distant organisms and may mimic the cytoprotective effects of dietary restriction... 
Vascular aging | Polyphenol | Stroke | Tobacco | Sirtuin 1 | Inflammation | Apoptosis | sirtuin 1 | LIFE-SPAN | MITOCHONDRIAL SUPEROXIDE-PRODUCTION | ELECTRON-SPIN-RESONANCE | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | DNA-DAMAGE | apoptosis | NECROSIS-FACTOR-ALPHA | polyphenol | stroke | CORONARY-ARTERIES | NAD(P)H OXIDASE | ENDOTHELIUM-DEPENDENT DILATION | inflammation | vascular aging | CALORIC RESTRICTION | PERIPHERAL VASCULAR DISEASE | tobacco | NF-KAPPA-B | Carotid Arteries - drug effects | Smoking - adverse effects | Inflammation - pathology | Reactive Oxygen Species - metabolism | Rats, Wistar | Apoptosis - drug effects | Male | NF-kappa B - metabolism | Stilbenes - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Smoking - physiopathology | Inflammation Mediators - metabolism | Resveratrol | Carotid Arteries - enzymology | Models, Animal | Sirtuins - genetics | Cytoprotection | DNA Damage - drug effects | Coronary Vessels - drug effects | Coronary Vessels - enzymology | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Smoke - adverse effects | Cells, Cultured | Rats | Arteries - drug effects | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Inflammation - etiology | Smoking - metabolism | Phenotype | Animals | Arteries - enzymology | Arteries - physiopathology | Smoking - pathology | Inflammation - prevention & control | Oxidative Stress - drug effects | Vasodilation - drug effects | Endothelial Cells - enzymology | Inflammation - enzymology | Sirtuins - metabolism | Endothelial Cells - drug effects | Inflammation - physiopathology
Journal Article
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2016, Volume 374, Issue 13, pp. 1221 - 1231
Journal Article
Lancet neurology, ISSN 1474-4422, 2015, Volume 14, Issue 4, pp. 361 - 367
Journal Article
PloS one, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0128141
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 2, pp. e669S - e690S
Journal Article
Cardiovascular research, ISSN 1755-3245, 2010, Volume 87, Issue 3, pp. 569 - 577
.... In the present study, we investigated the potential cardiovascular therapeutic effects of a long-term treatment with an arginase inhibitor in adult spontaneously hypertensive rats (SHR... 
Remodelling | Arginase | Spontaneously hypertensive rat | Endothelial function | Arteries | CARDIAC & CARDIOVASCULAR SYSTEMS | RESISTANCE ARTERIES | BLOOD-PRESSURE REDUCTION | GENE POLYMORPHISMS | STIFFNESS | CONTRACTION | NITRIC-OXIDE | ASSOCIATION | CONTRIBUTES | ANTIHYPERTENSIVE TREATMENT | Carotid Arteries - drug effects | Mesenteric Arteries - physiopathology | Compliance | Arginase - metabolism | Rats, Inbred WKY | Endothelium, Vascular - drug effects | Heart Diseases - prevention & control | Hypertension - drug therapy | Male | Mesenteric Arteries - drug effects | Endothelium, Vascular - enzymology | Arginine - analogs & derivatives | Dose-Response Relationship, Drug | Time Factors | Carotid Arteries - enzymology | Blood Pressure - drug effects | Membrane Proteins - metabolism | Aorta - physiopathology | Arginase - antagonists & inhibitors | Hypertension - enzymology | Hypertension - genetics | Aorta - enzymology | Disease Models, Animal | Rats, Inbred SHR | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Aorta - drug effects | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Rats | Myocardium - pathology | Heart Diseases - enzymology | Vasoconstriction - drug effects | Hypertension - pathology | Hypertension - physiopathology | Cardiovascular Agents - pharmacology | Collagen - metabolism | Animals | Carotid Arteries - physiopathology | Arginine - pharmacology | Cyclooxygenase 2 - metabolism | Fibrosis | Nitric Oxide Synthase - metabolism | Cyclooxygenase 1 - metabolism | Vasodilation - drug effects | Mesenteric Arteries - enzymology | Heart Diseases - pathology
Journal Article
Atherosclerosis, ISSN 0021-9150, 2015, Volume 241, Issue 1, pp. 111 - 120
Abstract In vitro , insulin has mitogenic effects on vascular smooth muscle cells (VSMC... 
Cardiovascular | Endothelial nitric oxide synthase | Neointima | Angioplasty | Insulin | Re-endothelialization | MIGRATION | ACTIVATION | PHOSPHORYLATION | MECHANISMS | RAT CAROTID-ARTERY | INTIMAL HYPERPLASIA | BALLOON INJURY | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | EXPRESSION | IN-STENT RESTENOSIS | Femoral Artery - pathology | Phosphorylation | Carotid Artery Injuries - drug therapy | Drug Implants | Vascular System Injuries - enzymology | Male | Vascular System Injuries - drug therapy | Nitric Oxide Synthase Type III - deficiency | Dose-Response Relationship, Drug | Femoral Artery - enzymology | Vascular System Injuries - pathology | Femoral Artery - injuries | Time Factors | Aorta, Thoracic - drug effects | Nitric Oxide Synthase Type III - metabolism | Aorta, Thoracic - pathology | Carotid Artery Injuries - pathology | Disease Models, Animal | Vascular System Injuries - physiopathology | Vasodilator Agents - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - injuries | Insulin - administration & dosage | Re-Epithelialization - drug effects | Femoral Artery - drug effects | Nitric Oxide Synthase Type III - genetics | Rats, Sprague-Dawley | Mice, Knockout | Nitric Oxide Synthase Type III - antagonists & inhibitors | Aorta, Thoracic - enzymology | Cell Movement - drug effects | Animals | Carotid Artery Injuries - enzymology | Signal Transduction - drug effects | Carotid Artery Injuries - physiopathology | Carotid Artery, Common - enzymology | Carotid Artery, Common - drug effects | Carotid Artery, Common - pathology | Vasodilation - drug effects | Growth | Nitric oxide | Analysis | Physiological aspects | Statistics | Endothelium
Journal Article
by Anand, Sonia S and Bosch, Jackie and Eikelboom, John W and Connolly, Stuart J and Aboyans, Victor and Alings, Marco and Kakkar, Ajay K and Lewis, Basil S and Störk, Stefan and Zhu, Jun and Lopez-Jaramillo, Patricio and O'Donnell, Martin and Commerford, Patrick J and Vinereanu, Dragos and Ryden, Lars and Misselwitz, Frank and Varigos, John D and Vanassche, Thomas and Chen, Edmond and Branch, Kelley and Leong, Darryl P and Bangdiwala, Shrikant I and Hart, Robert G and Yusuf, Salim and CARTASEGNA, LUIS and VICO, MARISA and HOMINAL, MIGUEL ANGEL and HASBANI, EDUARDO and CACCAVO, ALBERTO and VOGEL, DANIEL and HRABAR, ADRIAN and CUNEO, CARLOS and MACKINNON, IGNACIO J and AHUAD GUERRERO, RODOLFO ANDRES and COSTABEL, JUAN PABLO and BARTOLACCI, INES PALMIRA and BARBIERI, MARIA and GOMEZ VILAMAJO, OSCAR and GARCIA DURAN, RUBEN OMAR and SCHIAVI, LILIA BEATRIZ and INGARAMO, ADRIAN and BORDONAVA, ANSELMO PAULINO and PELAGAGGE, MARIA JOSE and NOVARETTO, LEONARDO and ALBISU DI GENNERO, JUAN PABLO and IBANEZ SAGGIA, LUZ MARIA and ALVAREZ, MOIRA and VITA, NESTOR ALEJANDRO and MACIN, STELLA MARIS and CARDONA, MARCELO and SARJANOVICH, RODOLFO JUAN and CUADRADO, JESUS and LITVAK BRUNO, MARCOS RAUL and CHACON, CAROLINA and MAFFEI, LAURA ELENA and GRINFELD, DIEGO and VENSENTINI, NATALIA and MAJUL, CLAUDIO RODOLFO and LUCIARDI, HECTOR LUCAS and FERRE PACORA, FREDY ANTONI and VAN DEN HEUVEL, PAUL and VERHAMME, PETER and DEBONNAIRE, PHILIPPE and VAN DE BORNE, PHILIPPE and LEROY, JEAN and SCHROE, HERMAN and ELEGEERT, IVAN and HOFFER, ETIENNE and DUJARDIN, KARL and ABRANTES, JOSE ANTONIO and MANENTI, EULER and MAIA, LILIA and HERNANDES, MAURO and ROSSI DOS SANTOS, FABIO and ZIMMERMANN, SERGIO LUIZ and ABIB JR, EDUARDO and LEAES, PAULO and BOTELHO, ROBERTO and BRAILE, MARIA and IZUKAWA, NILO and TANAJURA, LUIZ FERNANDO and SERRANO JUNIOR, CARLOS VICENTE and NASI, LUIZ ANTONIO and TYTUS, RICHARD and PANDEY, SHEKHAR and LONN, EVA and CHA, JAMES and BABAPULLE, MOHAN and LAMY, ANDRE and KIAII, BOB and BHARGAVA, RAKESH and MEHTA, PRAVINSAGAR and HILL, LAURIE and FELL, DAVID and LAM, ANDY and AL-QOOFI, FAISAL and PETRELLA, ROBERT and GLANZ, ANTHONY and NOISEUX, NICOLAS and MERALI, FATIMA and ... and COMPASS Investigators and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The Lancet (British edition), ISSN 0140-6736, 2018, Volume 391, Issue 10117, pp. 219 - 229
Patients with peripheral artery disease have an increased risk of cardiovascular morbidity and mortality... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | MANAGEMENT | THERAPY | OUTPATIENTS | CARDIOVASCULAR EVENT RATES | PREVENTION | RISK | Myocardial Infarction - epidemiology | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Carotid Artery Diseases - complications | Male | Peripheral Arterial Disease - complications | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Incidence | Dose-Response Relationship, Drug | Rivaroxaban - adverse effects | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Cardiovascular Diseases - mortality | Female | Stroke - epidemiology | Aspirin - therapeutic use | Lower Extremity - surgery | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Myocardial Infarction - etiology | Rivaroxaban - therapeutic use | Carotid Artery Diseases - drug therapy | Platelet Aggregation Inhibitors - adverse effects | Stroke - prevention & control | Double-Blind Method | Drug Administration Schedule | Peripheral Arterial Disease - drug therapy | Carotid Artery Diseases - epidemiology | Morbidity | Factor Xa Inhibitors - therapeutic use | Stroke - etiology | Peripheral Arterial Disease - epidemiology | Factor Xa Inhibitors - adverse effects | Aged | Myocardial Infarction - prevention & control | Amputation - statistics & numerical data | Hemorrhage - chemically induced | Lower Extremity - blood supply | Cardiac arrhythmia | Anticoagulants | Aspirin | Stroke | Heart attacks | Medical imaging | Mortality | Clinical trials | Cardiovascular disease | Patients | Disease control | Evidence-based medicine | Carotid arteries | Disease prevention | Coronary vessels | Blood pressure | Carotid artery | Acute coronary syndromes | Thromboembolism | Health risk assessment | Cardiovascular Diseases | Factor Xa Inhibitors | Klinisk medicin | Hemorrhage | epidemiology | Rivaroxaban | administration & dosage | Combination | Amputation | Drug | drug therapy | chemically induced | complications | prevention & control | Peripheral Arterial Disease | etiology | Clinical Medicine | Myocardial Infarction | statistics & numerical data | blood supply | Carotid Artery Diseases | Platelet Aggregation Inhibitors | adverse effects | mortality | Lower Extremity | Dose-Response Relationship | therapeutic use | surgery
Journal Article