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Journal Article
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 10/2009, Volume 297, Issue 4, pp. 1535 - 1543
Atherosclerosis is closely associated with disturbed flow characterized by low and oscillatory shear stress, but studies directly linking disturbed flow to... 
Endothelial dysfunction | Shear stress | Inflammation | Atherosclerosis | Endothelium | atherosclerosis | endothelium | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | FLUID SHEAR-STRESS | NITRIC-OXIDE SYNTHASE | BONE MORPHOGENIC PROTEIN-4 | MOUSE AORTAS | endothelial dysfunction | IN-VITRO | shear stress | inflammation | PERIPHERAL VASCULAR DISEASE | E-DEFICIENT MICE | EXPRESSION | NADPH OXIDASES | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Apolipoproteins E - deficiency | Tunica Intima - physiopathology | Carotid Artery Diseases - physiopathology | Stress, Mechanical | Endothelium, Vascular - drug effects | Male | Vasodilation | Dose-Response Relationship, Drug | NADPH Oxidases - deficiency | RNA - isolation & purification | Ligation | Time Factors | Carotid Artery Diseases - pathology | Computer Simulation | Dietary Fats - administration & dosage | Superoxides - metabolism | NADPH Oxidases - genetics | Female | Disease Models, Animal | Carotid Artery Diseases - etiology | Vasodilator Agents - pharmacology | Models, Cardiovascular | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Gene Expression Regulation | Regional Blood Flow | Disease Progression | Mice, Knockout | Tunica Intima - metabolism | Animals | Tunica Intima - pathology | Carotid Arteries - physiopathology | Apolipoproteins E - genetics | Carotid Artery Diseases - genetics | Carotid Arteries - surgery | Endothelium, Vascular - pathology | Carotid Arteries - pathology | Mice | Physiological aspects | Research | RNA | Risk factors | Arteries | Innovative Methodology
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 16, pp. 1620 - 1630
Since torcetrapib, an inhibitor of cholesteryl ester transfer protein, markedly increases levels of high-density lipoprotein cholesterol and lowers levels of... 
INTIMA-MEDIA THICKNESS | RANDOMIZED CONTROLLED-TRIALS | MEDICINE, GENERAL & INTERNAL | TRANSFER PROTEIN INHIBITOR | CHOLESTERYL ESTER TRANSFER | CARDIOVASCULAR-DISEASE | DOUBLE-BLIND | HDL CHOLESTEROL | CORONARY-DISEASE | SECONDARY PREVENTION | HIGH-DENSITY-LIPOPROTEIN | Carotid Arteries - drug effects | Cholesterol Ester Transfer Proteins - antagonists & inhibitors | Prospective Studies | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Male | Quinolines - pharmacology | Atherosclerosis - etiology | Carotid Artery Diseases - pathology | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Drug Therapy, Combination | Pyrroles - therapeutic use | Carotid Artery Diseases - drug therapy | Hyperlipoproteinemia Type II - complications | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Carotid Artery Diseases - etiology | Double-Blind Method | Hyperlipoproteinemia Type II - blood | Disease Progression | Atorvastatin Calcium | Anticholesteremic Agents - therapeutic use | Cholesterol, HDL - blood | Heterozygote | Carotid Arteries - pathology | Quinolines - therapeutic use | Anticholesteremic Agents - pharmacology | Hypercholesterolemia | High density lipoproteins | Atherosclerosis | Anticholesteremic agents | Dosage and administration | Research | Drug therapy | Cardiovascular disease | Diet | Apolipoproteins | Cholesterol
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2003, Volume 349, Issue 25, pp. 2399 - 2406
Journal Article
Atherosclerosis, ISSN 0021-9150, 08/2017, Volume 263, pp. 405 - 411
Familial hypercholesterolemia (FH) is a common inherited disorder of low density lipoprotein-cholesterol (LDL-C) metabolism. It is associated with higher risk... 
Carotid intima media thickness | Coronary artery calcification | Polygenic hypercholesterolemia | Familial hypercholesterolemia | Preclinical atherosclerosis | INTIMA-MEDIA THICKNESS | DIAGNOSIS | MUTATION DETECTION | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK | GENETIC CAUSES | BEAM COMPUTED-TOMOGRAPHY | LIPOPROTEIN | UK | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | PROGRESSION | Humans | Middle Aged | England | Male | Asymptomatic Diseases | Coronary Artery Disease - blood | Multifactorial Inheritance | Netherlands | Carotid Artery Diseases - diagnostic imaging | Coronary Angiography - methods | DNA Mutational Analysis | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Hyperlipoproteinemia Type II - complications | Severity of Illness Index | Genetic Predisposition to Disease | Carotid Artery Diseases - etiology | Coronary Artery Disease - etiology | Hyperlipoproteinemia Type II - blood | Carotid Intima-Media Thickness | Risk Factors | Biomarkers - blood | Computed Tomography Angiography | Coronary Artery Disease - diagnostic imaging | Phenotype | Carotid Artery Diseases - blood | Aged | Polymorphism, Single Nucleotide | Mutation | Hyperlipoproteinemia Type II - genetics | Heart | Genetic aspects | Hypercholesterolemia | Coronary heart disease | Low density lipoproteins | Atherosclerosis | Cardiac patients | Physiological aspects | Single nucleotide polymorphisms
Journal Article
Journal Article