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Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2011, Volume 31, Issue 7, pp. 1565 - 1572
OBJECTIVE—Interleukin 17A (IL17A) is involved in many inflammatory processes, but its role in atherosclerosis remains controversial. We examined the role of... 
atherosclerosis | nitric oxide | cytokines | vascular biology | superoxide | IL-17A | INTACT | FOAM CELLS | PLAQUE | MONOCYTE MIGRATION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | T-CELLS | Antibodies, Neutralizing - administration & dosage | Inflammation - pathology | Spleen - immunology | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Dendritic Cells - immunology | Humans | Middle Aged | Interleukin-17 - immunology | Male | Aorta - metabolism | Interferon-gamma - metabolism | Aortic Diseases - metabolism | Inflammation - metabolism | Ligation | Lymphocytes - immunology | Time Factors | Carotid Artery Diseases - pathology | Dietary Fats | Superoxides - metabolism | Female | Angiotensin II | Carotid Artery Diseases - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Carotid Artery Diseases - immunology | Interleukin-17 - blood | Atherosclerosis - pathology | Atherosclerosis - immunology | Aortic Diseases - immunology | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Aorta - immunology | Inflammation - immunology | Interleukin-17 - deficiency | Atherosclerosis - metabolism | Mice, Knockout | Interleukin-17 - metabolism | Aortic Diseases - genetics | Animals | Apolipoproteins E - genetics | Carotid Artery Diseases - genetics | Inflammation - genetics | Carotid Arteries - surgery | Aged | Mice | Nitric Oxide - metabolism | Interferon-gamma | Reactive oxygen species | Apolipoprotein E | Interleukin 17 | Atherosclerosis
Journal Article
Journal Article
Circulation research, ISSN 0009-7330, 2014, Volume 114, Issue 5, pp. 770 - 779
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2010, Volume 30, Issue 9, pp. 1832 - 1841
Journal Article
Atherosclerosis, ISSN 0021-9150, 2011, Volume 216, Issue 1, pp. 125 - 130
Abstract Objective To assess the influence of the TNFA rs1800629 (G > A) polymorphism in the risk of cardiovascular (CV) disease and subclinical... 
Cardiovascular | Cardiovascular disease | Genetics | rs1800629 | TNFA | Rheumatoid arthritis | Atherosclerosis | Rs1800629 | INTIMA-MEDIA THICKNESS | CORONARY-ARTERY DISEASE | MYOCARDIAL-INFARCTION | FACTOR-ALPHA GENE | PROMOTER POLYMORPHISM | ENDOTHELIAL FUNCTION | TUMOR-NECROSIS-FACTOR | HEART-DISEASE | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Male | Cardiovascular Diseases - pathology | Arthritis, Rheumatoid - complications | Cardiovascular Diseases - genetics | Vasodilation | HLA-DR Antigens - genetics | Carotid Artery Diseases - pathology | Brachial Artery - physiopathology | Female | Odds Ratio | Carotid Artery Diseases - immunology | Cardiovascular Diseases - physiopathology | Genetic Predisposition to Disease | Risk Assessment | Gene Frequency | Risk Factors | Proportional Hazards Models | Logistic Models | Epitopes | Chi-Square Distribution | Spain | Cardiovascular Diseases - immunology | Arthritis, Rheumatoid - genetics | Phenotype | HLA-DR3 Antigen - genetics | HLA-DRB1 Chains | Carotid Artery Diseases - genetics | Aged | Carotid Arteries - pathology | Polymorphism, Single Nucleotide | Arthritis, Rheumatoid - immunology | Rheumatoid factor | Care and treatment | Histocompatibility antigens | Peptides | HLA histocompatibility antigens | Genetic aspects | Foot-and-mouth disease | Cardiovascular diseases | Risk factors | Endothelium
Journal Article
Circulation, ISSN 0009-7322, 08/2009, Volume 120, Issue 5, pp. 427 - 436
Journal Article
Atherosclerosis, ISSN 0021-9150, 2010, Volume 212, Issue 1, pp. 252 - 259
Abstract Objective To examine n −3 polyunsaturated fatty acid (PUFA) incorporation into atherosclerotic plaques and the association with plaque inflammation... 
Cardiovascular | Inflammation | Metalloproteinase | Fatty acid | Atherosclerosis | Plaque | MORTALITY | FISH CONSUMPTION | MYOCARDIAL-INFARCTION | SUDDEN-DEATH | DIETARY SUPPLEMENTATION | RISK | CARDIOVASCULAR-DISEASE | CAROTID PLAQUES | LONG-CHAIN N-3 | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | Carotid Artery Diseases - surgery | Inflammation - pathology | Matrix Metalloproteinases - genetics | Eicosapentaenoic Acid - analogs & derivatives | Humans | Middle Aged | England | RNA, Messenger - analysis | Male | Eicosapentaenoic Acid - administration & dosage | Foam Cells - drug effects | Endarterectomy, Carotid | Inflammation - metabolism | Capsules | Inflammation Mediators - analysis | Carotid Artery Diseases - pathology | Inflammation - drug therapy | T-Lymphocytes - drug effects | Aged, 80 and over | Adult | Female | Phospholipids - metabolism | Carotid Artery Diseases - metabolism | Cytokines - genetics | Carotid Artery Diseases - drug therapy | Carotid Artery Diseases - immunology | Double-Blind Method | Administration, Oral | Eicosapentaenoic Acid - metabolism | Gene Expression Regulation | Treatment Outcome | Inflammation - immunology | Chi-Square Distribution | Docosahexaenoic Acids - administration & dosage | Preoperative Care | Eicosapentaenoic Acid - blood | Docosahexaenoic Acids - blood | T-Lymphocytes - immunology | Aged | Foam Cells - immunology | Dietary Supplements | Drug Combinations | Inflammation - surgery | Rupture, Spontaneous | Unsaturated fatty acids | Esters | Omega-3 fatty acids
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2014, Volume 34, Issue 8, pp. 1668 - 1673
Coagulation factor XI is proposed as therapeutic target for anticoagulation. However, it is still unclear whether the antithrombotic properties of factor XI... 
Blood coagulation | Factor XI | Thrombosis | Atherosclerosis | atherosclerosis | INTRINSIC PATHWAY | factor XI | blood coagulation | CAROTID-ARTERY | MOUSE | VENOUS THROMBOSIS | DEFICIENCY | thrombosis | REDUCED INCIDENCE | IN-VIVO | COAGULATION | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | ANTISENSE OLIGONUCLEOTIDES | Carotid Arteries - metabolism | Inflammation - pathology | Platelet Adhesiveness | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Carotid Artery Diseases - complications | Male | Inflammation - blood | Time Factors | Carotid Artery Diseases - pathology | Blood Coagulation | Thrombosis - blood | Thrombosis - prevention & control | Disease Models, Animal | Carotid Artery Diseases - immunology | Atherosclerosis - pathology | Factor XI - genetics | Atherosclerosis - immunology | Mice, Inbred C57BL | Atherosclerosis - complications | Inflammation - immunology | Plaque, Atherosclerotic | Mice, Knockout | Atherosclerosis - blood | Platelet Aggregation | Collagen - metabolism | Thrombosis - pathology | Macrophages - metabolism | Animals | Blood Platelets - metabolism | Thrombosis - etiology | Apolipoproteins E - genetics | Carotid Artery Diseases - blood | Carotid Arteries - immunology | Carotid Artery Diseases - genetics | Oligonucleotides, Antisense - administration & dosage | Thrombosis - genetics | Carotid Arteries - pathology | Mice | Factor XI - metabolism | Fibrin - metabolism | Cholesterol, Dietary | Rupture, Spontaneous
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2013, Volume 33, Issue 4, pp. 679 - 686
OBJECTIVE—Unstable atherosclerotic lesions are prone to rupture, which leads to atherothrombosis. Chemokine (C-X-C motif) ligand 12 (CXCL12) promotes the... 
atherosclerosis | chemokine | STEM-CELLS | MOBILIZATION | INJURY | SDF-1 | BONE-MARROW-CELLS | CXCR4 | vascular biology | NEOINTIMA FORMATION | FACTOR-I | PLAQUE | plaque modification | RUPTURE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Stem Cells - immunology | Apolipoproteins E - deficiency | Male | X-Ray Microtomography | Chemokine CXCL2 - administration & dosage | RNA Interference | Carotid Artery Diseases - pathology | Bone Marrow Transplantation | Antigens, Ly - metabolism | Myocytes, Smooth Muscle - drug effects | Disease Models, Animal | Biomarkers - metabolism | Macrophages - pathology | Genotype | Mice, Transgenic | Chemotaxis - drug effects | Plaque, Atherosclerotic | Mice, Knockout | Muscle Proteins - genetics | Phenotype | Carotid Arteries - immunology | Carotid Artery Diseases - genetics | Fibrosis | Stem Cells - pathology | Mice | Endothelial Cells - pathology | Injections, Intravenous | Myocytes, Smooth Muscle - pathology | Stem Cells - metabolism | Flow Cytometry | Chemokine CXCL2 - genetics | Membrane Proteins - metabolism | Carotid Artery Diseases - metabolism | Chemokine CXCL2 - metabolism | Microfilament Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Macrophages - immunology | Carotid Artery Diseases - drug therapy | Carotid Artery Diseases - immunology | Proto-Oncogene Proteins c-sis - metabolism | Mice, Inbred C57BL | Cells, Cultured | Endothelial Cells - immunology | Animals | Apolipoproteins E - genetics | Myocytes, Smooth Muscle - immunology | Stem Cells - drug effects | Macrophages - drug effects | Carotid Arteries - pathology | Endothelial Cells - drug effects
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2010, Volume 30, Issue 9, pp. 1842 - 1848
Journal Article
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2015, Volume 35, Issue 1, pp. 79 - 86
The protein degrading activity of cathepsin C (CatC), combined with its role in leukocyte granule activation, suggests a contribution of this cystein protease... 
protease | inflammation | human | mice | Atherosclerosis | atherosclerosis | LOCALIZATION | ACTIVATION | ATHEROGENESIS | SERINE PROTEASES | EXPERIMENTAL ARTHRITIS | CHYMASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | T-CELLS | DIPEPTIDYL-PEPTIDASE-I | Carotid Artery Diseases - prevention & control | Atherosclerosis - genetics | Humans | Leukocytes - enzymology | Leukocytes - immunology | Atherosclerosis - enzymology | Time Factors | Carotid Artery Diseases - pathology | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - enzymology | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Carotid Arteries - enzymology | Female | Aortic Diseases - enzymology | Cell Differentiation | Aorta - enzymology | Aortic Diseases - pathology | Disease Models, Animal | Adaptive Immunity | Carotid Artery Diseases - immunology | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Aortic Diseases - immunology | Down-Regulation | Mice, Inbred C57BL | Cathepsin C - genetics | Cells, Cultured | Aorta - immunology | Foam Cells - enzymology | Immunity, Innate | Plaque, Atherosclerotic | Cathepsin C - metabolism | Disease Progression | Macrophage Activation | Mice, Knockout | Aorta - pathology | Aortic Diseases - genetics | Animals | Carotid Artery Diseases - enzymology | Carotid Arteries - immunology | Carotid Artery Diseases - genetics | Carotid Arteries - pathology | Foam Cells - immunology | Atherosclerosis - prevention & control
Journal Article