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Circulation, ISSN 0009-7322, 10/2013, Volume 128, Issue 18, pp. 2026 - 2038
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2014, Volume 34, Issue 8, pp. 1723 - 1730
OBJECTIVE—Perivascular adipose tissue (PVAT) expands during obesity, is highly inflamed, and correlates with coronary plaque burden and increased... 
Hyperplasia | Adipose tissue | ARTERIAL INJURY | adipose tissue | CAROTID ARTERIES | INTIMAL HYPERPLASIA | INSULIN-RESISTANCE | IN-VIVO | P-SELECTIN | CARDIOVASCULAR-DISEASE | hyperplasia | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | E-DEFICIENT MICE | ENDOTHELIAL GROWTH-FACTOR | Carotid Arteries - metabolism | Muscle, Smooth, Vascular - metabolism | Coculture Techniques | Humans | Actins - metabolism | Myocytes, Smooth Muscle - pathology | Neovascularization, Pathologic | Carotid Artery Injuries - etiology | Adipose Tissue - metabolism | Neointima | Time Factors | Transendothelial and Transepithelial Migration | Diet, High-Fat | Receptors, LDL - deficiency | Carotid Artery Injuries - genetics | Chemokine CCL2 - metabolism | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Biomarkers - metabolism | Receptors, LDL - genetics | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Chemokine CCL2 - genetics | Chemokine CCL2 - deficiency | Chemotaxis | Mice, Knockout | Macrophages - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Adipocytes - metabolism | Adipocytes - transplantation | Carotid Arteries - pathology | Mice | Adipose Tissue - transplantation | Culture Media, Conditioned - metabolism | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 07/2009, Volume 105, Issue 2, pp. 158 - 166
Journal Article
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2017, Volume 113, Issue 13, pp. 1627 - 1638
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2015, Volume 35, Issue 12, pp. 2579 - 2593
OBJECTIVE—Endoluminal vascular interventions such as angioplasty initiate a sterile inflammatory response resulting from local tissue damage. This response... 
hyperplasia | macrophages | carotid artery injuries | Angioplasty | HMGBI protein | STERILE INFLAMMATION | ISCHEMIA-REPERFUSION INJURY | TOLL-LIKE RECEPTOR-4 | THERAPY | PROTEIN HMG1 | IN-VIVO | RESTENOSIS | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | MICE | HEMATOLOGY | angioplasty | BOX 1 HMGB1 | Carotid Arteries - metabolism | Chemotaxis, Leukocyte | Vasculitis - metabolism | Cell Proliferation | Vascular System Injuries - genetics | Humans | Hyperplasia | Vasculitis - pathology | Myocytes, Smooth Muscle - pathology | Adaptor Proteins, Vesicular Transport - metabolism | HMGB1 Protein - genetics | Vascular System Injuries - pathology | Vasculitis - genetics | Neointima | Time Factors | Toll-Like Receptor 4 - deficiency | HMGB1 Protein - metabolism | Inflammation Mediators - metabolism | Carotid Artery Injuries - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | HMGB1 Protein - deficiency | Cytokines - metabolism | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Vascular System Injuries - metabolism | Animals | Carotid Arteries - pathology | Macrophages, Peritoneal - metabolism | Myeloid Differentiation Factor 88 - metabolism | Cell Movement | Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 09/2012, Volume 95, Issue 4, pp. 517 - 526
Proliferation and migration of vascular smooth muscle cells (VSMCs) can cause atherosclerosis and neointimal formation. MicroRNAs have been shown to regulate... 
MicroRNA-195 | Balloon-injured carotid artery | Human aorta smooth muscle cell | Neointimal formation | Atherosclerosis | D1 EXPRESSION | CARDIAC & CARDIOVASCULAR SYSTEMS | CYCLIN D1 | PROTEIN-KINASE | LESION FORMATION | P38 MAPK | SUPPRESSES TUMORIGENICITY | FIBROBLAST-GROWTH-FACTOR | KAPPA-B | BREAST-CANCER | IN-VITRO | Carotid Arteries - metabolism | Immunohistochemistry | Cyclin D1 - metabolism | Genetic Therapy | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Myocytes, Smooth Muscle - pathology | Male | MicroRNAs - metabolism | cdc42 GTP-Binding Protein - metabolism | Fibroblast Growth Factor 1 - genetics | In Situ Hybridization | Neointima | Transfection | Time Factors | Interleukin-1beta - metabolism | Inflammation Mediators - metabolism | Adenoviridae - genetics | Carotid Artery Injuries - genetics | Lipoproteins, LDL - metabolism | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Cells, Cultured | Computational Biology | Fibroblast Growth Factor 1 - metabolism | Gene Expression Regulation | Rats | Gene Expression Profiling - methods | Rats, Sprague-Dawley | Carotid Artery Injuries - therapy | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Cyclin D1 - genetics | cdc42 GTP-Binding Protein - genetics | Carotid Arteries - pathology | Genetic Vectors | Cell Movement | Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 06/2013, Volume 98, Issue 3, pp. 458 - 468
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2017, Volume 113, Issue 13, pp. 1653 - 1663
Aims Adventitial cells have been suggested to contribute to neointima formation, but the functional relevance and the responsible signalling pathways are... 
Fibroblasts | Smoothened | Neointima formation | Sonic Hedgehog | PROGENITOR CELLS | MIGRATION | CARDIAC & CARDIOVASCULAR SYSTEMS | INJURY | PHENOTYPE | PROLIFERATION | IL-6 | CHEMOATTRACTANT | SMOOTH-MUSCLE-CELLS | EXPRESSION | Carotid Arteries - metabolism | Femoral Artery - pathology | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Myocytes, Smooth Muscle - pathology | Hedgehog Proteins - metabolism | Male | Smoothened Receptor - metabolism | Adventitia - metabolism | Vascular System Injuries - pathology | Neointima | Time Factors | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - metabolism | Smoothened Receptor - antagonists & inhibitors | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Fibroblasts - metabolism | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Cytokines - metabolism | Paracrine Communication | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Adventitia - drug effects | Fibroblasts - pathology | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Fibroblasts - drug effects | Anilides - pharmacology | Femoral Artery - metabolism | Adventitia - pathology | Carotid Arteries - pathology | Pyridines - pharmacology | Cell Movement | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2014, Volume 34, Issue 2, pp. 355 - 364
OBJECTIVE—Vascular remodeling occurs after endothelial injury, resulting in smooth muscle cell (SMC) proliferation and vascular fibrosis. We previously... 
placental growth factor | receptors mineralocorticoid | vascular endothelial growth factor receptor-1 | aldosterone | myocytes smooth muscle | MORTALITY | OXIDATIVE STRESS | EVENTS | receptors | smooth muscle | myocytes | mineralocorticoid | BLOOD-PRESSURE | SPIRONOLACTONE | PERIPHERAL VASCULAR DISEASE | EPLERENONE | HYPERTENSION | HEMATOLOGY | EXPRESSION | BLOCKER | GENE-TRANSCRIPTION | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Receptors, Mineralocorticoid - agonists | Receptors, Mineralocorticoid - genetics | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Muscle, Smooth, Vascular - metabolism | Pregnancy Proteins - genetics | Myocytes, Smooth Muscle - pathology | Male | Pregnancy Proteins - metabolism | RNA, Messenger - metabolism | Receptors, Mineralocorticoid - deficiency | Time Factors | Carotid Artery Injuries - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Endothelial Cells - metabolism | Mice, Inbred C57BL | Aldosterone - pharmacology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Mice, Knockout | Antibodies - pharmacology | Muscle, Smooth, Vascular - pathology | Animals | Fibrosis | Placenta Growth Factor | Carotid Arteries - pathology | Cell Proliferation - drug effects | Mice | Endothelial Cells - pathology | Endothelial Cells - drug effects | Index Medicus | smooth muscle cells | mineralocorticoid receptor | vascular remodeling | VEGF
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 9, pp. 1683 - 1697
OBJECTIVE—Obesity is associated with elevated circulating leptin levels and hypothalamic leptin resistance. Leptin receptors (LepRs) are expressed on... 
vascular injury | endothelial cells | neointima | endothelin-1 | leptin | mice | obesity | PROGENITOR CELLS | ARTERIAL INJURY | BLOOD-PRESSURE | IN-VITRO | GROWTH-FACTORS | NITRIC-OXIDE | ETA-RECEPTOR | BALLOON ANGIOPLASTY | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | CRE-MEDIATED RECOMBINATION | HEMATOLOGY | Carotid Arteries - metabolism | Phosphorylation | Vascular Remodeling | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Receptors, Leptin - genetics | Leptin - metabolism | Myocytes, Smooth Muscle - pathology | Male | PPAR gamma - metabolism | Obesity - genetics | Neointima | Carotid Artery Injuries - complications | Diet, High-Fat | Female | Carotid Artery Injuries - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | STAT3 Transcription Factor - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Promoter Regions, Genetic | Paracrine Communication | Signal Transduction | Endothelial Cells - metabolism | Endothelin-1 - metabolism | Obesity - complications | Mice, Inbred C57BL | Cells, Cultured | Receptors, Endothelin - metabolism | Genotype | Integrases | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Receptor, TIE-2 - genetics | Receptors, Leptin - deficiency | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Carotid Arteries - pathology | Receptors, Leptin - metabolism | Endothelial Cells - pathology | Cell Movement | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2013, Volume 33, Issue 10, pp. 2355 - 2365
OBJECTIVE—Myocardin, a potent transcriptional coactivator of serum response factor, is involved in vascular development and promotes a contractile smooth... 
microRNAs | myocardin | carotid arteries | muscle, smooth | signal transduction | MUSCLE-CELL DIFFERENTIATION | STEM-CELLS | PHENOTYPIC MODULATION | ATHEROSCLEROSIS | ANGIOPLASTY | MESSENGER-RNA | muscle | IN-VIVO | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | smooth | Carotid Stenosis - prevention & control | Cell Proliferation | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Myocytes, Smooth Muscle - pathology | Male | MicroRNAs - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Carotid Stenosis - metabolism | Neointima | Transfection | Time Factors | Carotid Stenosis - genetics | Nuclear Proteins - deficiency | Trans-Activators - genetics | Carotid Artery Injuries - genetics | 3' Untranslated Regions | Nuclear Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Carotid Artery, Common - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Rats | Nuclear Proteins - metabolism | Carotid Stenosis - pathology | Mice, Knockout | Carotid Artery Injuries - prevention & control | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Trans-Activators - deficiency | Apolipoproteins E - genetics | Carotid Artery, Common - pathology | Trans-Activators - metabolism | Mice | Cell Movement | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0168914 - e0168914
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2016, Volume 36, Issue 9, pp. 1947 - 1961