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Journal Article
Stroke, ISSN 0039-2499, 02/2010, Volume 41, Issue 2, pp. 295 - 299
Background and Purpose-In ischemic stroke, the site of arterial obstruction has been shown to influence recanalization and clinical outcomes. However, this has... 
Myocardial infarction | Ischemic stroke | Thrombolysis | Arterial obstruction | TISSUE-PLASMINOGEN ACTIVATOR | myocardial infarction | ACUTE ISCHEMIC-STROKE | RECANALIZATION | arterial obstruction | thrombolysis | RANDOMIZED-TRIAL | PERIPHERAL VASCULAR DISEASE | 3 H | PERFUSION-DIFFUSION MISMATCH | ischemic stroke | CLINICAL NEUROLOGY | Infarction, Middle Cerebral Artery - physiopathology | Predictive Value of Tests | Carotid Artery Thrombosis - drug therapy | Prospective Studies | Outcome Assessment (Health Care) | Humans | Middle Aged | Male | Antifibrinolytic Agents - adverse effects | Tissue Plasminogen Activator - adverse effects | Cerebral Arteries - drug effects | Thrombolytic Therapy - methods | Aged, 80 and over | Antifibrinolytic Agents - administration & dosage | Female | Magnetic Resonance Angiography - methods | Infarction, Middle Cerebral Artery - drug therapy | Intracranial Thrombosis - drug therapy | Intracranial Thrombosis - pathology | Severity of Illness Index | Intracranial Thrombosis - physiopathology | Carotid Artery Thrombosis - physiopathology | Thrombolytic Therapy - statistics & numerical data | Cerebral Arteries - physiopathology | Tissue Plasminogen Activator - administration & dosage | Treatment Outcome | Brain Ischemia - physiopathology | Image Processing, Computer-Assisted - methods | Infarction, Middle Cerebral Artery - pathology | Emergency Medical Services - statistics & numerical data | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Cerebral Arteries - pathology | Aged | Emergency Medical Services - methods | Injections, Intravenous - statistics & numerical data | Carotid Artery Thrombosis - pathology
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 10/2015, Volume 132, Issue 15, pp. 1414 - 1424
BACKGROUND—Platelets are central to the process of hemostasis, rapidly aggregating at sites of blood vessel injury and acting as coagulation nidus sites. On... 
membrane ballooning | blood platelets | procoagulant-spreading | blood coagulation | collagen | cell-derived microparticles | fluorescent imaging | APOPTOSIS | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | HUMAN-SKIN WOUNDS | CHANNEL | PERIPHERAL VASCULAR DISEASE | PHOSPHATIDYLSERINE EXPOSURE | TMEM16A | MORPHOLOGY | HEMOSTATIC PLUG | Carotid Artery Thrombosis - blood | Carotid Artery Thrombosis - drug therapy | Humans | Sodium - metabolism | Cytochalasin D - pharmacology | Cell-Derived Microparticles | Heterocyclic Compounds, 4 or More Rings - pharmacology | Phospholipid Transfer Proteins - deficiency | Thrombin - biosynthesis | Microtubules - drug effects | Chlorides - metabolism | Carotid Artery Thrombosis - chemically induced | Cell Membrane - metabolism | Anoctamins | Thrombosis - prevention & control | Blood Platelets - drug effects | Cell Membrane - drug effects | Amides - pharmacology | Acetazolamide - pharmacology | Cell Size - drug effects | Water - metabolism | Cell Membrane - ultrastructure | Actomyosin - metabolism | Cell Adhesion | Cell Shape - drug effects | Animals | Blood Platelets - metabolism | Phospholipid Transfer Proteins - physiology | Blood Platelets - ultrastructure | Collagen | Blood Coagulation Disorders - blood | Mice | Pyridines - pharmacology | Cell Shape - physiology | Balloon dilatation | Usage | Research | Blood platelets | Hemostasis | Analysis
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 11/2009, Volume 102, Issue 5, pp. 829 - 836
Sulfated polysaccharides from marine invertebrates have well-defined structures and constitute a reliable class of molecules for structure-activity... 
Invertebrate | Antithrombotic activity | Fucoidan | Heparin | Sulfated fucans | Anticoagulant activity | ACTIVATION | anticoagulant activity | FUCOSYLATED CHONDROITIN SULFATE | VENOUS THROMBOSIS | CELL-PROLIFERATION | fucoidan | heparin | MOLECULAR-WEIGHT FUCOIDAN | FUCANS | SEA-CUCUMBER | antithrombotic activity | PERIPHERAL VASCULAR DISEASE | ANTICOAGULANT ACTIVITIES | invertebrate | HEMATOLOGY | ANTITHROMBOTIC ACTIVITIES | Sea Cucumbers - chemistry | Fibrinolytic Agents - chemistry | Fucose - chemistry | Carotid Artery Thrombosis - drug therapy | Rats, Wistar | Molecular Sequence Data | Male | Structure-Activity Relationship | Fibrinolytic Agents - isolation & purification | Anticoagulants - toxicity | Polysaccharides - toxicity | Anticoagulants - chemistry | Polysaccharides - isolation & purification | Fibrinolytic Agents - therapeutic use | Polysaccharides - chemistry | Female | Molecular Structure | Drug Evaluation, Preclinical | Anticoagulants - isolation & purification | Carbohydrate Sequence | Polysaccharides - therapeutic use | Venous Thrombosis - drug therapy | Rats | Anticoagulants - therapeutic use | Chondroitin Sulfates - isolation & purification | Chondroitin Sulfates - pharmacology | Chondroitin Sulfates - chemistry | Chondroitin Sulfates - therapeutic use | Enzyme Activation - drug effects | Polysaccharides - pharmacology | Fibrinolytic Agents - pharmacology | Animals | Blood Coagulation - drug effects | Anticoagulants - pharmacology | Factor XII - metabolism | Chondroitin Sulfates - toxicity | Thrombosis - drug therapy | Fibrinolytic Agents - toxicity | Hemorrhage - chemically induced | Carbohydrate Conformation
Journal Article
Journal Article
Stroke, ISSN 0039-2499, 2002, Volume 33, Issue 8, pp. 2066 - 2071
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87026
There is considerable interest in defining new agents or targets for antithrombotic purposes. The 5-HT2A receptor is a G-protein coupled receptor (GPCR)... 
PATHWAYS | STIMULATION | DEPRESSED-PATIENTS | 5-HYDROXYTRYPTAMINE | THROMBOSIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DISEASE | ARTERY | AGGREGATION | ANTIPLATELET | Carotid Artery Thrombosis - drug therapy | Immunoprecipitation | Ticlopidine - pharmacology | Calcium - metabolism | Humans | Male | Carotid Artery Thrombosis - metabolism | Serotonin - pharmacology | Receptor, Serotonin, 5-HT2A - chemistry | Serotonin Receptor Agonists - pharmacology | Cyproheptadine - pharmacology | Flow Cytometry | Pizotyline - pharmacology | Platelet Function Tests | Platelet Aggregation Inhibitors - pharmacology | Indoles - pharmacology | Antidepressive Agents - pharmacology | Platelet Aggregation - drug effects | Mice, Inbred C57BL | Platelet Aggregation - physiology | Hemorrhage - metabolism | Serotonin Antagonists - pharmacology | Piperazines - pharmacology | Blotting, Western | Ticlopidine - analogs & derivatives | Adenosine Diphosphate - pharmacology | Hemorrhage - drug therapy | Animals | Mice | Platelet Activation - drug effects | Carotid Artery Thrombosis - pathology | Hemorrhage - pathology | Occlusion | Health sciences | Flow cytometry | Phosphorylation | G protein-coupled receptors | Calcium | Kinases | ADP | Experiments | Bleeding | Blood platelets | Hemostasis | Antidepressants | Hemostatics | Carotid artery | Thromboembolism | Phosphatidylserine | Drug dosages | Pharmaceutical sciences | Tyrosine | Calcium (intracellular) | Serotonin | Glycoprotein | Platelet aggregation | FDA approval | Serotonin S2 receptors | Thrombosis | Studies | Cytometry | Cyproheptadine | Pharmacy | Clopidogrel | In vivo methods and tests | P-selectin
Journal Article