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Brain research, ISSN 0006-8993, 2007, Volume 1134, Issue 1, pp. 1 - 11
Abstract Quantitative RT-PCR (qRT-PCR) and Western blotting studies on transporters at the blood–brain barrier (BBB... 
Neurology | Transporters | Brain microvessels | Rat | Blood–brain barrier | Blood-brain barrier | blood-brain barrier | ORGAN DISTRIBUTION | MRP1 | transporters | rat | MULTIDRUG-RESISTANCE PROTEINS | brain microvessels | ASTROCYTES | NEUROSCIENCES | P-GLYCOPROTEIN ABCB1 | EFFLUX TRANSPORT | LASER CAPTURE MICRODISSECTION | LUMINAL SIDE | FUNCTIONAL EXPRESSION | ENDOTHELIAL-CELLS | Biomarkers - metabolism | Glial Fibrillary Acidic Protein - genetics | Organ Culture Techniques - methods | Microcirculation - metabolism | Endothelial Cells - metabolism | Gene Expression Regulation - genetics | Biomarkers - analysis | Rats | Male | RNA, Messenger - metabolism | Rats, Sprague-Dawley | Blood-Brain Barrier - metabolism | Carrier Proteins - genetics | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Cerebral Arteries - metabolism | Membrane Transport Proteins - genetics | Multidrug Resistance-Associated Proteins - genetics | Genetic research | Brain | Breast cancer | RNA | Gene expression | Intermediate filament proteins | Cerebral Arteries | Endothelial Cells | Biological Markers | Biochemistry, Molecular Biology | Genomics | Gene Expression Regulation | Glial Fibrillary Acidic Protein | Life Sciences | Microcirculation | Membrane Transport Proteins | P-Glycoprotein | RNA, Messenger | Organ Culture Techniques | Multidrug Resistance-Associated Proteins | Blood-Brain Barrier | Carrier Proteins
Journal Article
Acta Neurochirurgica, ISSN 0001-6268, 1/2012, Volume 154, Issue 1, pp. 93 - 103
Journal Article
Autophagy, ISSN 1554-8635, 2018, Volume 15, Issue 1, pp. 34 - 57
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 488, Issue 7413, pp. 670 - 674
...)-1 beta, IL-18 and high-mobility group box 1 (HMGB1)(1-5). By studying HMGB1 release mechanisms, here we identify a role for double-stranded RNA-dependent protein kinase... 
PATHWAYS | APOPTOSIS | ACID | PROTEIN-KINASE PKR | MULTIDISCIPLINARY SCIENCES | INFECTION | NLRP3 INFLAMMASOME | ELF2-ALPHA | STRESS | BINDING | SUBSTRATE RECOGNITION | Crystallins - metabolism | Interleukin-6 - analysis | Phosphorylation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | eIF-2 Kinase - metabolism | Humans | Salmonella Infections - immunology | Male | Salmonella Infections - metabolism | HMGB1 Protein - secretion | Interleukin-1beta - blood | eIF-2 Kinase - deficiency | Adenosine Triphosphate - pharmacology | CARD Signaling Adaptor Proteins - metabolism | Transfection | Interleukin-6 - blood | Rotenone - pharmacology | Female | Membrane Proteins - metabolism | Escherichia coli - physiology | Macrophages, Peritoneal - drug effects | eIF-2 Kinase - genetics | Calcium-Binding Proteins - metabolism | Cell Line | Salmonella typhimurium - physiology | Interleukin-18 - blood | Salmonella typhimurium - immunology | Inflammasomes - agonists | Mice, Inbred C57BL | Peritonitis - metabolism | Cells, Cultured | Escherichia coli - immunology | Antigens, Bacterial - pharmacology | Escherichia coli Infections - metabolism | eIF-2 Kinase - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Carrier Proteins - metabolism | Bacterial Toxins - pharmacology | Uric Acid - pharmacology | RNA, Double-Stranded - immunology | RNA, Double-Stranded - pharmacology | Escherichia coli Infections - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | HMGB1 Protein - blood | Physiological aspects | Chromosomal proteins | Research | Cytokines | Aluminum | Health aspects | Proteins | E coli | Pathogenesis | Plasmids | Bone marrow | Bacteria | Kinases
Journal Article
Cancer cell, ISSN 1535-6108, 2016, Volume 29, Issue 4, pp. 508 - 522
.... In contrast, SHH-medulloblastoma, a less curable disease subtype, contains an intact blood brain barrier, rendering this tumor impermeable and resistant to chemotherapy... 
LUNG-CANCER | ANGIOGENESIS | ONCOLOGY | PATHWAY | IN-VIVO | VINCRISTINE | TUMOR | CNS | CENTRAL-NERVOUS-SYSTEM | SUBGROUPS | CHEMOTHERAPY | CELL BIOLOGY | Humans | Neoplasm Proteins - physiology | Cerebellar Neoplasms - blood supply | Culture Media, Conditioned - pharmacology | Genetic Vectors - therapeutic use | Medulloblastoma - secretion | Recombinant Fusion Proteins - metabolism | Endothelium, Vascular - ultrastructure | Cerebellar Neoplasms - secretion | Wnt Proteins - genetics | Membrane Proteins - physiology | Pericytes - pathology | Glucose Transporter Type 1 - physiology | Antineoplastic Agents - pharmacokinetics | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Vincristine - pharmacokinetics | Disease Models, Animal | Carrier Proteins - physiology | Cerebellar Neoplasms - drug therapy | Transduction, Genetic | Genetic Association Studies | Genotype | Mice, Transgenic | Cerebellar Neoplasms - genetics | Tight Junctions - ultrastructure | Animals | Wnt Signaling Pathway - drug effects | Endothelium, Vascular - metabolism | Paracrine Communication - drug effects | Vincristine - therapeutic use | Medulloblastoma - blood supply | Mice | Wnt Proteins - physiology | Medulloblastoma - drug therapy | Drug Resistance, Neoplasm - physiology | Medulloblastoma - classification | Blood-Brain Barrier | Chemotherapy | Medulloblastoma | Brain tumors | Genetic aspects | Permeability | Cells | Cancer | Neurophysiology | Endothelium
Journal Article
The EMBO journal, ISSN 1460-2075, 2006, Volume 25, Issue 17, pp. 3955 - 3965
Histone acetyltransferases (HATs) p300 and CREB‐binding protein (CBP) function as co‐activators for a variety of sequence... 
transcription regulation | histone acetyltransferase | protein phosphorylation | Protein phosphorylation | Histone acetyltransferase | Transcription regulation | DNA-BINDING | STEM-CELLS | MICE DEFICIENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYB | HISTONE ACETYLTRANSFERASE ACTIVITY | SYNERGISTICALLY ACTIVATE | FETAL LIVER HEMATOPOIESIS | CELL BIOLOGY | COACTIVATOR P300 | CREB-BINDING-PROTEIN | FUSION PROTEIN | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Transcriptional Activation | Histone Acetyltransferases - genetics | Molecular Sequence Data | Embryo, Mammalian - metabolism | Blood Vessels - embryology | p300-CBP Transcription Factors - genetics | Hematopoiesis | Histone Acetyltransferases - metabolism | Cell Cycle Proteins - genetics | Acetylation | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Cell Line | Embryo, Mammalian - pathology | Core Binding Factor Alpha 2 Subunit - metabolism | Embryo, Mammalian - blood supply | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-fos - metabolism | Transcription Factors - genetics | Proto-Oncogene Proteins c-myb - metabolism | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | p300-CBP Transcription Factors - metabolism | Animals | Carrier Proteins - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Neovascularization, Pathologic - genetics | Trans-Activators - metabolism | Mice | Enzyme Activation | Core Binding Factor Alpha 2 Subunit - genetics | Proteins | Blood vessels | Genetics | Molecular biology | Kinases | Rodents
Journal Article
Vaccine, ISSN 0264-410X, 2016, Volume 34, Issue 46, pp. 5612 - 5622
.... • PfRipr is a promising candidate for next generation P. falciparum malaria blood-stage vaccine. 
Allergy and Immunology | PfRipr | Plasmodium falciparum | Malaria blood-stage vaccine | Growth inhibition | Polymorphism | ANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | PFRH5 | PROTECTION | CELL-FREE SYSTEM | ANTIGENS | IMMUNOLOGY | DISCOVERY | GENETIC DIVERSITY | DENSITY | TRIAL | INVASION | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Reticulocytes - parasitology | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Antibodies, Protozoan - blood | Merozoite Surface Protein 1 - isolation & purification | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Protozoan Proteins - chemistry | Carrier Proteins - immunology | Plasmodium falciparum - chemistry | Rabbits | Antigens, Protozoan - chemistry | Merozoites - physiology | Recombinant Proteins - chemistry | Reticulocytes - metabolism | Polymorphism, Genetic | Cross Reactions | Merozoite Surface Protein 1 - administration & dosage | Carrier Proteins - genetics | Animals | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Uganda | Erythrocytes - parasitology | Protozoan Proteins - immunology | Vaccines | Malaria | Malaria vaccine | Protein binding | Antigens | Medical research | DNA binding proteins | Recombinant proteins | Genetic polymorphisms | Biological diversity | Anopheles | Analysis | Medicine, Experimental | Conflicts of interest | Laboratories | Genes | Erythrocytes
Journal Article
Atherosclerosis, ISSN 0021-9150, 2015, Volume 241, Issue 1, pp. 130 - 137
...). We examined AT secretion of the hepatokine, Fetuin-A, LBP, sCD14 and HMGB-1, and toll-like receptor 2 and 4 protein levels in MetS and controls... 
Cardiovascular | Adipose tissue | TLR | Metabolic syndrome | Lipopolysaccharide binding protein | Fetuin A | CARDIAC & CARDIOVASCULAR SYSTEMS | MARKER | MONOCYTES | HMGB1 | HEART | OBESITY | PATTERN | INSULIN-RESISTANCE | INFLAMMATION | PERIPHERAL VASCULAR DISEASE | LIGAND | EXPRESSION | Up-Regulation | alpha-2-HS-Glycoprotein - analysis | Carrier Proteins - secretion | Humans | Middle Aged | Male | Acute-Phase Proteins - genetics | RNA, Messenger - metabolism | Case-Control Studies | HMGB1 Protein - genetics | HMGB1 Protein - secretion | Young Adult | Metabolic Syndrome - blood | Subcutaneous Fat - metabolism | Adiposity | Subcutaneous Fat - secretion | HMGB1 Protein - metabolism | Metabolic Syndrome - physiopathology | Adult | Female | Adipogenesis | Disease Models, Animal | Carrier Proteins - blood | Acute-Phase Proteins - secretion | Mice, Inbred C57BL | alpha-2-HS-Glycoprotein - secretion | Membrane Glycoproteins - blood | Obesity - physiopathology | Biomarkers - blood | 3T3-L1 Cells | Lipopolysaccharide Receptors - blood | Membrane Glycoproteins - genetics | Obesity - metabolism | Carrier Proteins - genetics | Membrane Glycoproteins - secretion | Animals | Toll-Like Receptor 4 - blood | Metabolic Syndrome - diagnosis | Metabolic Syndrome - genetics | Adipocytes - metabolism | Toll-Like Receptor 2 - blood | alpha-2-HS-Glycoprotein - metabolism | Mice, Obese | Aged | Mice | alpha-2-HS-Glycoprotein - genetics | HMGB1 Protein - blood | Adipose tissues | Medical colleges | Insulin resistance | Mitogens | Atherosclerosis | Protein binding
Journal Article
Biochimica et biophysica acta. Biomembranes, ISSN 0005-2736, 07/2015, Volume 1848, Issue 7, pp. 1619 - 1628
Journal Article