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International Journal of Pharmaceutics, ISSN 0378-5173, 10/2012, Volume 436, Issue 1-2, pp. 840 - 850
Nanoparticulate drug delivery system possesses distinct advantages for brain drug delivery. However, its amount that reach the brain is still not satisfied.... 
Nanoparticles | Blood–brain barrier (BBB) | Penetratin | Brain targeting | Cell-penetrating peptides | Blood-brain barrier (BBB) | PERMEABILITY SCREEN | BARRIER | CNS DELIVERY | MDCK CELL-LINE | IN-VITRO | TRANSPORT | POLYMERIC NANOPARTICLES | PEPTIDES | PHARMACOKINETICS | INTRACELLULAR DELIVERY | PHARMACOLOGY & PHARMACY | Fluorescent Dyes - pharmacokinetics | Nanoparticles - chemistry | Cell-Penetrating Peptides - pharmacokinetics | Drug Carriers - administration & dosage | Coumarins - chemistry | Male | Polyethylene Glycols - chemistry | Thiazoles - administration & dosage | Drug Carriers - chemistry | Thiazoles - pharmacokinetics | Brain - metabolism | Carrier Proteins - administration & dosage | Madin Darby Canine Kidney Cells | Carrier Proteins - chemistry | Fluorescent Dyes - administration & dosage | Cell-Penetrating Peptides - chemistry | Cell Survival - drug effects | Fluorescent Dyes - chemistry | Coumarins - administration & dosage | Coumarins - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Rats | Rats, Sprague-Dawley | Mice, Inbred ICR | Polyethylene Glycols - administration & dosage | Brain - drug effects | Animals | Mice, Nude | Dogs | Thiazoles - chemistry | Drug Carriers - pharmacokinetics | Mice | Nanoparticles - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Carrier Proteins - pharmacokinetics | Drugs | Drug delivery systems | Peptides | Vehicles | Index Medicus
Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2005, Volume 145, Issue 8, pp. 1093 - 1102
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 6/2012, Volume 29, Issue 6, pp. 1562 - 1569
Delivery of therapeutic proteins across the blood-brain barrier (BBB) is severely limited by their size and biochemical properties. Here we showed that a... 
Biomedical Engineering | Biochemistry, general | Biomedicine | protein delivery | Pharmacy | RDP fusion protein | Medical Law | Pharmacology/Toxicology | brain targeting | stroke | PATHWAYS | DRUG-DELIVERY | TRANSDUCTION | VIRULENCE | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES | SUPPLEMENTATION | GENE | DISEASE | PHARMACOLOGY & PHARMACY | BRAIN | Viral Proteins - pharmacokinetics | Capillary Permeability | Injections, Intravenous | Humans | Half-Life | Luciferases - administration & dosage | Male | Infarction, Middle Cerebral Artery - metabolism | Drug Carriers | beta-Galactosidase - administration & dosage | Rabies virus - metabolism | Tissue Distribution | Neuroprotective Agents - pharmacokinetics | Luciferases - chemistry | Luciferases - pharmacokinetics | Drug Compounding | Glycoproteins - pharmacokinetics | Viral Proteins - administration & dosage | Infarction, Middle Cerebral Artery - drug therapy | beta-Galactosidase - chemistry | Glycoproteins - chemistry | Neuroprotective Agents - administration & dosage | Recombinant Fusion Proteins - administration & dosage | Disease Models, Animal | Neuroprotective Agents - chemistry | Viral Proteins - chemistry | Peptide Fragments - administration & dosage | Peptide Fragments - pharmacokinetics | Technology, Pharmaceutical - methods | beta-Galactosidase - pharmacokinetics | Infarction, Middle Cerebral Artery - pathology | Recombinant Fusion Proteins - chemistry | Chemistry, Pharmaceutical | Glycoproteins - administration & dosage | Blood-Brain Barrier - metabolism | Brain-Derived Neurotrophic Factor - administration & dosage | Brain-Derived Neurotrophic Factor - chemistry | Peptide Fragments - chemistry | Animals | Brain-Derived Neurotrophic Factor - pharmacokinetics | Recombinant Fusion Proteins - pharmacokinetics | Mice | Proteins | Peptides | Neurons | Luciferase | Rabies | Central nervous system | Health aspects | Stroke | Drug delivery systems | Nervous system | Glycoproteins | Pharmacology | Index Medicus | Neuroprotection | Brain-derived neurotrophic factor | Blood-brain barrier | Fusion protein | beta -Galactosidase | Molecular weight
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 11/2015, Volume 495, Issue 1, pp. 9 - 18
Oral drug delivery is the most preferred route for patients; however, the low solubility of drugs and the resultant poor absorption compromise the benefits of... 
Absorption mechanism | Nanoemulsions | Insoluble drug | Pharmacokinetics | Globular protein | Solidification | MECHANISM | VIVO | NANOCARRIERS | MICELLES | FORMULATION | DIRECT CYTOSOLIC DELIVERY | TRANSPORT | NANOSUSPENSIONS | PHARMACOLOGY & PHARMACY | ABSORPTION | Nanoparticles - chemistry | Soybean Proteins - pharmacokinetics | Emulsions - adverse effects | Humans | Bile Acids and Salts - chemistry | Drug Carriers - administration & dosage | Biological Availability | Fenofibrate - chemistry | Soybean Proteins - chemistry | Drug Carriers - chemistry | Intestinal Absorption | Tissue Distribution | Emulsions - administration & dosage | Bile Acids and Salts - administration & dosage | Protein Denaturation | Water - chemistry | Bile Acids and Salts - pharmacokinetics | Caco-2 Cells | Cell Survival - drug effects | Soybean Proteins - administration & dosage | Administration, Oral | Emulsions - chemistry | Nanoparticles - ultrastructure | Solubility | Fenofibrate - administration & dosage | Rats | Chemistry, Pharmaceutical | Fenofibrate - blood | Particle Size | Fenofibrate - pharmacokinetics | Animals | Suspensions - pharmacokinetics | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Emulsions - pharmacokinetics | Drugs | Drug delivery systems | Analysis | Gastrointestinal system | Vehicles | Index Medicus
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 2/2010, Volume 27, Issue 2, pp. 264 - 271
The aim was to investigate that a bio-degradable alginate and poly lactide-co-glycolide (PLG) system capable of delivering growth factors sequentially would be... 
Biomedical Engineering | Biochemistry, general | alginate | polymer | Biomedicine | Pharmacy | angiogenesis | PDGF | VEGF | Medical Law | Pharmacology/Toxicology | Angiogenesis | Polymer | Alginate | FACTOR DELIVERY | DISEASE | ISCHEMIA | PHARMACOLOGY & PHARMACY | NEOVASCULARIZATION | CHEMISTRY, MULTIDISCIPLINARY | PDGF-BB | Neovascularization, Physiologic - drug effects | Polymers - administration & dosage | Drug Carriers - administration & dosage | Hexuronic Acids - administration & dosage | Male | Hexuronic Acids - pharmacokinetics | Angiogenesis Inhibitors - administration & dosage | Intercellular Signaling Peptides and Proteins - pharmacokinetics | Polyesters - administration & dosage | Glucuronic Acid - administration & dosage | Intercellular Signaling Peptides and Proteins - administration & dosage | Alginates - pharmacokinetics | Ischemia - metabolism | Angiogenesis Inhibitors - pharmacokinetics | Glucuronic Acid - pharmacokinetics | Random Allocation | Mice, Knockout | Neovascularization, Physiologic - physiology | Polyesters - pharmacokinetics | Alginates - administration & dosage | Animals | Ischemia - drug therapy | Hindlimb - blood supply | Polymers - pharmacokinetics | Hindlimb - drug effects | Drug Carriers - pharmacokinetics | Mice | Delayed-Action Preparations | Drug Delivery Systems - methods | Medical colleges | Platelet-derived growth factor | Environmental health | Neovascularization | Polymers | Apolipoproteins | Health aspects | Vascular endothelial growth factor | Public health | Biomedical engineering | Proteins | Blood vessels | Drug delivery systems | Pharmacology | Cellular biology | Index Medicus | Research Paper
Journal Article
Journal Article
Journal Article