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Arthritis Research and Therapy, ISSN 1478-6354, 10/2013, Volume 15, Issue 5, pp. R155 - R155
Introduction: Myeloid dendritic cells (mDCs) are potent T cell activating antigen presenting cells that have been suggested to play a crucial role in the... 
T-HELPER-1 | IMMUNITY | CYTOKINE PRODUCTION | HUMAN PERIPHERAL-BLOOD | SYNOVIUM | SUBSETS | MONOCYTES | RHEUMATOLOGY | CD1C | RECEPTORS | LYMPHOCYTES | Immunoassay | Arthritis, Rheumatoid - blood | Dendritic Cells - immunology | Humans | Middle Aged | Glycoproteins - metabolism | Male | Th2 Cells - immunology | Th1 Cells - immunology | Th1 Cells - metabolism | Arthritis, Rheumatoid - metabolism | Lymphocyte Activation - immunology | Flow Cytometry | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Cartilage, Articular - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Adult | Female | Synovial Fluid - cytology | Dendritic Cells - metabolism | Chemokines - immunology | Cytokines - immunology | Antigens, CD1 - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Cells, Cultured | Th2 Cells - metabolism | Synovial Fluid - immunology | Cartilage, Articular - pathology | Glycoproteins - immunology | Antigens, CD1 - metabolism | Th17 Cells - immunology | T-Lymphocytes - immunology | Aged | Chemokines - metabolism | Arthritis, Rheumatoid - immunology | Cartilage, Articular - immunology | Histocompatibility antigens | Immune response | Dendritic cells | Rheumatoid arthritis | HLA histocompatibility antigens | Fluorescence | B cells | Comparative analysis | Immunity | Interferon gamma | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 8, pp. 4879 - 4886
The CD200 receptor (CD200R) acts as a negative regulator of myeloid cells by interacting with its widely expressed ligand CD200. Using mutants expressed in... 
STEM-CELLS | ACTIVATION | PROGNOSTIC-FACTOR | INHIBITION | DOCKING PROTEIN | PHOSPHORYLATION | NEGATIVE REGULATION | MACROPHAGES | DOWN-REGULATION | SURFACE-PROTEINS | IMMUNOLOGY | Phosphoproteins - immunology | Antigens, CD - immunology | p120 GTPase Activating Protein - metabolism | Humans | Glycoproteins - metabolism | p120 GTPase Activating Protein - genetics | Phosphoproteins - metabolism | Antigens, CD - metabolism | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Matrilin Proteins | Signal Transduction - immunology | ras GTPase-Activating Proteins - genetics | Interleukin-4 - pharmacology | RNA, Small Interfering - immunology | Myeloid Cells - immunology | Adaptor Proteins, Signal Transducing - immunology | Antigens, Surface - metabolism | Myeloid Cells - drug effects | Interleukin-8 - metabolism | Extracellular Matrix Proteins - metabolism | Macrophages - immunology | ras GTPase-Activating Proteins - metabolism | DNA-Binding Proteins - immunology | Cartilage Oligomeric Matrix Protein | RNA-Binding Proteins - immunology | Antigens, Surface - genetics | Rats | Receptors, Cell Surface - metabolism | Phosphoproteins - genetics | Receptors, Cell Surface - immunology | Glycoproteins - immunology | Macrophages - metabolism | Animals | Extracellular Matrix Proteins - immunology | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Myeloid Cells - metabolism | Macrophages - drug effects | Mice | ras GTPase-Activating Proteins - immunology | Adaptor Proteins, Signal Transducing - metabolism | Interleukin-8 - immunology | Antigens, Surface - immunology | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 528 - 540
Journal Article
Journal of Interferon & Cytokine Research, ISSN 1079-9907, 01/2013, Volume 33, Issue 1, pp. 1 - 8
In view of well-established immunomodulatory properties of Lactobacillus , present investigation was carried out to evaluate antioxidant and anti-inflammatory... 
Research Reports | RHEUMATOID-ARTHRITIS | ADJUVANT-INDUCED ARTHRITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYTOKINE | IMMUNOLOGY | INTERLEUKIN-6 | CELL BIOLOGY | PATHOGENESIS | REACTIVE OXYGEN | ARTICULAR-CARTILAGE | MICE | NF-KAPPA-B | EXPRESSION | Probiotics - administration & dosage | Rats, Wistar | Glutathione - metabolism | Antioxidants - metabolism | Tumor Necrosis Factor-alpha - blood | Interleukin-17 - immunology | Oxidative Stress - immunology | Interleukin-10 - blood | Male | Arthritis, Experimental - microbiology | Host-Pathogen Interactions - immunology | Interleukin-1beta - blood | Signal Transduction - immunology | Time Factors | Interleukin-6 - blood | Arthritis, Experimental - prevention & control | Lipid Peroxidation - drug effects | Tumor Necrosis Factor-alpha - immunology | Lactobacillus acidophilus - immunology | Lactobacillus casei - physiology | Superoxide Dismutase - metabolism | Interleukin-17 - blood | Glutathione Peroxidase - metabolism | Inflammation - microbiology | Catalase - immunology | Lactobacillus acidophilus - physiology | Interleukin-1beta - immunology | Rats | Arthritis, Experimental - immunology | Inflammation - immunology | Probiotics - pharmacology | Lactobacillus casei - immunology | Catalase - metabolism | Glutathione - immunology | Interleukin-4 - immunology | Superoxide Dismutase - immunology | Interleukin-4 - blood | Animals | Signal Transduction - drug effects | Glutathione Peroxidase - immunology | Interleukin-6 - immunology | Oxidative Stress - drug effects | Interleukin-10 - immunology | Lipid Peroxidation - immunology | Index Medicus
Journal Article
Drugs & Aging, ISSN 1170-229X, 02/2010, Volume 27, Issue 2, pp. 95 - 115
Several recent in vitro investigations and experimental studies performed in animal models of osteoarthritis (OA) sustained the previously held view that... 
Osteoarthritis, pathogenesis | Cytokine-inhibitors, therapeutic use | Elderly | Osteoarthritis, treatment | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Geriatrics/Gerontology | Tumor Necrosis Factor-alpha - metabolism | Interleukin-18 - immunology | Interleukin-6 - antagonists & inhibitors | Cartilage - pathology | Humans | Interleukin-18 - antagonists & inhibitors | Antirheumatic Agents - immunology | Interleukin-17 - immunology | Synovial Fluid - metabolism | Osteoarthritis - drug therapy | Synovial Fluid - drug effects | Insulin-Like Growth Factor I - immunology | Signal Transduction - immunology | Interleukin-1 - immunology | Tumor Necrosis Factor-alpha - immunology | Fibroblast Growth Factor 2 - physiology | Interleukin-1 - antagonists & inhibitors | Joints - metabolism | Antirheumatic Agents - therapeutic use | Cytokines - immunology | Transforming Growth Factor beta - immunology | Cartilage - immunology | Interleukin-1beta - analysis | Osteoarthritis - immunology | Transforming Growth Factor beta - physiology | Interleukin-1beta - immunology | Joints - pathology | Arthritis, Experimental | Cartilage, Articular - pathology | Interleukin-7 - immunology | Interleukin-17 - antagonists & inhibitors | Joints - immunology | Interleukin-6 - immunology | Interleukin 1 Receptor Antagonist Protein | Platelet-Derived Growth Factor | Aged | Cytokines - antagonists & inhibitors | Interleukin-7 - antagonists & inhibitors | Cartilage, Articular - immunology | Insulin-Like Growth Factor I - metabolism | Interleukins | Tumor necrosis factor | Physiological aspects | Research | Drug therapy | Health aspects | Osteoarthritis | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 04/2006, Volume 107, Issue 8, pp. 3221 - 3228
Mammalian Glyco_18-domain-containing proteins include catalytically active chitinases and chitinase-like proteins with cytokine activity involved in host... 
RHEUMATOID-ARTHRITIS | ACIDIC MAMMALIAN CHITINASE | SERUM YKL-40 | CYTOSOLIC PH | HUMAN CHITOTRIOSIDASE | GENE-EXPRESSION | ANTIGEN-PRESENTING CELLS | ECF-L | HEMATOLOGY | CARTILAGE | FAMILY | Bronchoalveolar Lavage Fluid | Golgi Apparatus - enzymology | Gene Expression Regulation, Enzymologic - drug effects | Macrophage Activation - genetics | Dexamethasone - immunology | Humans | Anti-Inflammatory Agents - immunology | Receptors, Lymphocyte Homing - immunology | Chitinases - genetics | Protein Transport - immunology | Dexamethasone - pharmacology | Golgi Apparatus - immunology | Carrier Proteins - immunology | Macrophages, Alveolar - immunology | Cytokines - immunology | Anti-Inflammatory Agents - pharmacology | Macrophage Activation - immunology | Cells, Cultured | Up-Regulation - genetics | Inflammation - immunology | Protein Structure, Tertiary - genetics | Chitinases - biosynthesis | Protein Transport - genetics | Macrophages, Alveolar - enzymology | Up-Regulation - drug effects | Carrier Proteins - genetics | Receptors, Lymphocyte Homing - biosynthesis | Up-Regulation - immunology | Gene Expression Regulation, Enzymologic - genetics | Cell Adhesion Molecules, Neuronal - biosynthesis | Chitinases - immunology | Macrophages, Alveolar - cytology | Gene Expression Regulation, Enzymologic - immunology | Macrophage Activation - drug effects | Inflammation - enzymology | Lysosomes - immunology | Cell Adhesion Molecules, Neuronal - immunology | Cytokines - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e45478 - e45478
Objective: The S100A9 and S100A8 proteins are highly expressed by neutrophils and monocytes and are part of a group of damage-associated molecular pattern... 
RHEUMATOID-ARTHRITIS | BETA INTEGRIN MAC-1 | PROTEIN MRP-14 | CELLS | URATE MONOHYDRATE CRYSTALS | HUMAN NEUTROPHILS | SYNOVIAL-FLUID | MULTIDISCIPLINARY SCIENCES | DISEASE | FACTOR-KAPPA-B | JOINT INFLAMMATION | Bone and Bones - pathology | Calgranulin B - metabolism | Cartilage - pathology | Autoantibodies - blood | Humans | Leukocyte L1 Antigen Complex - metabolism | Monocytes - immunology | Leukocyte L1 Antigen Complex - immunology | Arthritis, Experimental - metabolism | Transendothelial and Transepithelial Migration - drug effects | Antibodies, Neutralizing - immunology | Inflammation - metabolism | Calgranulin B - immunology | Inflammation Mediators - metabolism | Female | Antibodies, Monoclonal - immunology | Cytokines - immunology | Inflammation Mediators - immunology | Cytokines - metabolism | Antibodies, Monoclonal - pharmacology | Neutrophils - drug effects | Neutrophils - immunology | Antibodies, Neutralizing - pharmacology | Arthritis, Experimental - immunology | Inflammation - immunology | Cell Adhesion - drug effects | Transendothelial and Transepithelial Migration - immunology | Cell Adhesion - immunology | Monocytes - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Autoantibodies - immunology | Animals | Mice | Development and progression | Inflammation | Genetic aspects | Arthritis | Research | Disease | Leukocyte migration | Medical services | Antibodies | Stimulation | Experiments | Inflammatory diseases | Interleukin 6 | Proteins | Fibroblasts | Tumor necrosis factor-TNF | Immune response | Cytokines | Computational fluid dynamics | Secretion | Neutrophils | Rheumatology | Leukocytes (neutrophilic) | Tumor necrosis factor-α | Joint diseases | Damage patterns | White blood cells | Immune systems | Monocytes | S100A9 protein | Rheumatoid arthritis | Collagen | Infiltration | Monocyte chemoattractant protein 1 | Cell migration | Chemokines | Integrity | Index Medicus
Journal Article
Cellular Immunology, ISSN 0008-8749, 07/2012, Volume 278, Issue 1-2, pp. 35 - 44
Mesenchymal stem cells derived from human umbilical cord Wharton's jelly (hWJMSCs) became prospective seed cell candidate for tissue engineering and cell-based... 
Immune character | Transplantation tolerance | WJMSCs | Chondrogenic differenciation | TOLERANCE | MECHANISMS | IMMUNOLOGY | HLA-G | TRANSPLANTATION | CELL BIOLOGY | RESPONSES | IMMUNOGENICITY | DIFFERENTIATION | EXPRESSION | MARROW STROMAL CELLS | IMMUNOLOGICAL-PROPERTIES | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Antigens, CD - immunology | Transforming Growth Factors - genetics | Humans | Umbilical Cord - cytology | Transplantation, Heterologous | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Dinoprostone - immunology | Mesenchymal Stromal Cells - immunology | Mesenchymal Stromal Cells - cytology | Umbilical Cord - metabolism | Transforming Growth Factors - immunology | Cartilage - cytology | Hepatocyte Growth Factor - genetics | Cell Differentiation | HLA-G Antigens - immunology | HLA-G Antigens - genetics | Wharton Jelly - immunology | Cartilage - immunology | Rabbits | Wharton Jelly - metabolism | Gene Expression | Signal Transduction | Dinoprostone - genetics | Hepatocyte Growth Factor - immunology | Umbilical Cord - immunology | Immune Tolerance | Mesenchymal Stromal Cells - metabolism | Rats | Vascular Endothelial Growth Factor A - immunology | Cartilage - metabolism | Animals | Interleukin-10 - genetics | Interleukin-10 - immunology | Mesenchymal Stem Cell Transplantation | Wharton Jelly - cytology | Stem cells | Index Medicus | Antibodies
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 07/2014, Volume 66, Issue 7, pp. 1779 - 1788
Objective. Obesity is a major risk factor for the development of osteoarthritis (OA) that is associated with a state of low-grade inflammation and increased... 
OBESITY | RISK-FACTORS | NUTRITION EXAMINATION SURVEY | FREE FATTY-ACIDS | INSULIN-RESISTANCE | 3RD NATIONAL-HEALTH | ENDOPLASMIC-RETICULUM STRESS | RHEUMATOLOGY | KNEE OSTEOARTHRITIS | ASSOCIATION | HAND OSTEOARTHRITIS | Interleukin-1beta - pharmacology | Apoptosis - drug effects | Chondrocytes - immunology | Humans | Middle Aged | Palmitates - immunology | Extracellular Matrix - immunology | Extracellular Matrix - metabolism | Synovial Membrane - drug effects | Fatty Acids, Nonesterified - pharmacology | Young Adult | Chondrocytes - drug effects | Oleic Acid - pharmacology | Cattle | Cyclooxygenase 2 - genetics | Palmitates - pharmacology | Adult | Osteoarthritis, Knee - immunology | Cyclooxygenase 2 - immunology | Fatty Acids, Nonesterified - immunology | Interleukin-6 - genetics | Extracellular Matrix - drug effects | Cells, Cultured | Interleukin-1beta - immunology | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 4 - metabolism | Drug Synergism | Animals | Apoptosis - immunology | Oleic Acid - immunology | Interleukin-6 - immunology | Aged | Cartilage, Articular - drug effects | Cartilage, Articular - immunology | Osteoarthritis, Knee - drug therapy | Synovial Membrane - cytology | Fibroblasts | Cytokines | Gene expression | Rodents | Index Medicus | Abridged Index Medicus | fatty acids | Osteoarthritis | cartilage
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 06/2011, Volume 13, Issue 3, pp. R93 - R93
Introduction: Epigallocatechin-3-gallate (EGCG) is a bioactive polyphenol of green tea and exerts potent anti-inflammatory effects by inhibiting signaling... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | GREEN TEA | TUMOR-NECROSIS-FACTOR | COLONY-STIMULATING FACTOR | NITRIC-OXIDE SYNTHASE | LEUKEMIA INHIBITORY FACTOR | FACTOR-KAPPA-B | HUMAN ARTICULAR CHONDROCYTES | RHEUMATOLOGY | HUMAN OSTEOARTHRITIS CHONDROCYTES | Tumor Necrosis Factor-alpha - metabolism | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-8 - genetics | Chondrocytes - cytology | Interleukin-1beta - pharmacology | Interleukin-1 Receptor-Associated Kinases - genetics | Gene Expression - drug effects | Chondrocytes - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Nitrites - metabolism | NF-kappa B - metabolism | TNF Receptor-Associated Factor 6 - immunology | Osteoarthritis - drug therapy | MAP Kinase Signaling System - immunology | Chondrocytes - drug effects | Intercellular Signaling Peptides and Proteins - metabolism | Drug Interactions | Interleukin-1beta - metabolism | Interleukin-1 Receptor-Associated Kinases - immunology | Cytoprotection - drug effects | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-8 - metabolism | Osteoarthritis - pathology | TNF Receptor-Associated Factor 6 - genetics | Catechin - pharmacology | Cytoprotection - immunology | Interleukin-6 - metabolism | Interleukin-6 - genetics | Osteoarthritis - immunology | Interleukin-1beta - immunology | Antioxidants - pharmacology | MAP Kinase Signaling System - drug effects | Interleukin-6 - immunology | TNF Receptor-Associated Factor 6 - metabolism | Aged | Catechin - analogs & derivatives | Primary Cell Culture | Interleukin-8 - immunology | Intercellular Signaling Peptides and Proteins - immunology | Care and treatment | Physiological aspects | Polyphenols | Research | Diagnosis | Cartilage cells | Gene expression | Osteoarthritis | Health aspects | Index Medicus
Journal Article