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Osteoarthritis and Cartilage, ISSN 1063-4584, 2015, Volume 23, Issue 12, pp. 2288 - 2296
Summary Objective Hypoxia-inducible factor-2α (HIF-2α) transcriptionally upregulates Nampt in articular chondrocytes. NAMPT, which exhibits nicotinamide... 
Rheumatology | NAD+ biosynthesis | Hypoxia-inducible factor (HIF) | Sirtuin | Osteoarthritis | Chondrocytes | NAD | biosynthesis | APOPTOSIS | RHEUMATOLOGY | SIRTUINS | NAD(+) biosynthesis | SIRT1 | CARTILAGE | NUCLEUS PULPOSUS CELLS | METABOLISM | BIOLOGY | GROWTH | STRESS | ORTHOPEDICS | EXPRESSION | Sirtuin 1 - metabolism | Up-Regulation | Arthritis, Experimental - genetics | Immunoprecipitation | Matrix Metalloproteinase 12 - genetics | RNA, Messenger - metabolism | Sirtuin 1 - genetics | Arthritis, Experimental - metabolism | Sirtuin 2 - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Cartilage, Articular - metabolism | Sirtuins - genetics | Cytokines - genetics | Chondrocytes - metabolism | NAD - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Cytokines - metabolism | Matrix Metalloproteinase 13 - genetics | Matrix Metalloproteinase 3 - metabolism | Matrix Metalloproteinase 12 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Matrix Metalloproteinase 13 - metabolism | Sirtuin 2 - genetics | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Osteoarthritis, Knee - genetics | Mice | Matrix Metalloproteinase 3 - genetics | Sirtuins - metabolism | Osteoarthritis, Knee - metabolism | Index Medicus
Journal Article
Therapeutic Advances in Musculoskeletal Disease, ISSN 1759-720X, 8/2012, Volume 4, Issue 4, pp. 269 - 285
Chondrogenesis occurs as a result of mesenchymal cell condensation and chondroprogenitor cell differentiation. Following chondrogenesis, the chondrocytes... 
articular cartilage | mouse models | chondrogenesis | inflammation | osteoarthritis | Reviews
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