X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7735) 7735
Dissertation (201) 201
Book Chapter (80) 80
Publication (17) 17
Conference Proceeding (15) 15
Magazine Article (8) 8
Book / eBook (6) 6
Web Resource (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
crispr (4025) 4025
crispr/cas9 (3547) 3547
cas9 (3407) 3407
genomes (1926) 1926
crispr-cas9 (1923) 1923
humans (1785) 1785
animals (1764) 1764
crispr-cas systems (1466) 1466
mutation (1380) 1380
genome editing (1339) 1339
biochemistry & molecular biology (1260) 1260
genomics (1221) 1221
genome (1214) 1214
genes (1184) 1184
gene editing (1144) 1144
deoxyribonucleic acid--dna (1047) 1047
rna (1011) 1011
biotechnology & applied microbiology (1000) 1000
cell biology (985) 985
proteins (985) 985
genetic engineering (984) 984
expression (961) 961
gene expression (923) 923
gene (900) 900
dna (883) 883
mice (876) 876
crispr-cas systems - genetics (803) 803
gene editing - methods (743) 743
genetics & heredity (742) 742
system (732) 732
multidisciplinary sciences (703) 703
mutagenesis (681) 681
nucleases (677) 677
research (664) 664
genetic aspects (662) 662
analysis (660) 660
homologous recombination (613) 613
cells (607) 607
biology (599) 599
plant sciences (587) 587
endonuclease (583) 583
ribonucleic acid--rna (576) 576
genetic research (549) 549
biotechnology (515) 515
mutations (513) 513
clustered regularly interspaced short palindromic repeats (508) 508
rna, guide - genetics (506) 506
stem cells (503) 503
specificity (502) 502
human-cells (499) 499
base sequence (473) 473
transcription (472) 472
cancer (465) 465
genetics (454) 454
protein (447) 447
gene therapy (437) 437
biochemical research methods (433) 433
generation (420) 420
editing (406) 406
medicine, research & experimental (405) 405
in-vivo (390) 390
nuclease (390) 390
targeted mutagenesis (389) 389
life sciences (386) 386
gene targeting (380) 380
gene-expression (377) 377
methods (373) 373
genetic modification (370) 370
microbiology (370) 370
efficiency (364) 364
female (358) 358
zinc-finger nucleases (346) 346
review (344) 344
cell line (333) 333
activation (331) 331
homology (320) 320
genetic engineering - methods (318) 318
clustered regularly interspaced short palindromic repeats - genetics (310) 310
identification (310) 310
gen (309) 309
cloning (307) 307
hek293 cells (304) 304
crispr/cas9 system (301) 301
plasmids (298) 298
male (292) 292
genom (288) 288
plants (286) 286
mouse (280) 280
rice (279) 279
zebrafish (271) 271
enzymes (262) 262
one-step generation (260) 260
nucleotide sequence (259) 259
developmental biology (257) 257
gene deletion (256) 256
chemistry, multidisciplinary (253) 253
dna repair (253) 253
mouse model (251) 251
cleavage (250) 250
genome engineering (248) 248
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (7714) 7714
Chinese (274) 274
Japanese (46) 46
French (34) 34
Korean (26) 26
German (20) 20
Russian (11) 11
Spanish (11) 11
Portuguese (10) 10
Czech (5) 5
Italian (1) 1
Norwegian (1) 1
Persian (1) 1
Polish (1) 1
Slovenian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 33, pp. 10437 - 10442
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2015, Volume 54, Issue 41, pp. 12029 - 12033
Journal Article
Plant biotechnology journal, ISSN 1467-7644, 2018, Volume 16, Issue 11, pp. 1848 - 1857
Summary Previous studies revealed that the promoters for driving both Cas9 and sgRNAs are quite important for efficient genome editing by CRISPR/Cas9 in... 
targeted genome editing | CRISPR/Cas9 | dmc1 promoter | maize | RNA-GUIDED CAS9 | SPECIFICITY | ZEA-MAYS | CRISPR-CAS9 | PLANT SCIENCES | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PLANTS | GENERATION | ARABIDOPSIS | TARGETED MUTAGENESIS | MULTIPLEX | Analysis | Genomics | Plant genetics | Genetic research | Corn | Evolution | Plants | Gametes | CRISPR | DMC1 gene | Editing | Genomes | Loci | Promoters | Optimization | Mutants | Zygotes | Evolutionary conservation | Mutation | Target detection | s | Cas9
Journal Article
Plant and cell physiology, ISSN 1471-9053, 2016, Volume 57, Issue 5, pp. 1058 - 1068
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 08/2018, Volume 36, Issue 8, pp. 765 - 765
CRISPR-Cas9 is poised to become the gene editing tool of choice in clinical contexts. Thus far, exploration of Cas9-induced genetic alterations has been... 
CRISPR/CAS9 | SPECIFICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | EMBRYONIC STEM-CELLS | RNAS | CAS9 | MUTATIONS | NUCLEASES
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2018, Volume 57, Issue 10, pp. 2657 - 2661
Direct and rapid intracellular delivery of a functional Cas9/sgRNA complex using ultrasound‐powered nanomotors is reported. The Cas9/sgRNA complex is loaded... 
GFP knockout | CRISPR/Cas9 | intracellular delivery | nanowires | nanomotors | CRISPR | CRISPR-CAS9 | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | GENOME | GLUTATHIONE | Cas9 | MOTORS | CELL | EFFICIENCY | Proteins | Physiological aspects | Ultrasonic imaging | Incubation | Therapeutic applications | Green fluorescent protein | Intracellular | Nanowires | Ultrasound | Nanotechnology
Journal Article
Plant biotechnology journal, ISSN 1467-7644, 2018, Volume 16, Issue 1, pp. 292 - 297
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2016, Volume 113, Issue 11, pp. 2868 - 2873
A central challenge to the development of protein-based therapeutics is the inefficiency of delivery of protein cargo across the mammalian cell membrane,... 
Protein delivery | Genome editing | CRISPR/Cas9 | Cre recombinase | Lipid nanoparticle | THERAPEUTICS | genome editing | COMBINATORIAL LIBRARY | VIVO | RNA | CELLS IN-VITRO | CAS9 PROTEIN | TRANSFECTION | MULTIDISCIPLINARY SCIENCES | CANCER-THERAPY | lipid nanoparticle | protein delivery | INTRACELLULAR DELIVERY | Endonucleases - genetics | Thalamus - metabolism | Nanoparticles - chemistry | Humans | Green Fluorescent Proteins - genetics | Structure-Activity Relationship | Recombinant Proteins - biosynthesis | Endosomes - metabolism | Drug Carriers | Luminescent Proteins - biosynthesis | RNA - genetics | Cholesterol - chemistry | Endocytosis | Lipids - chemistry | Integrases - administration & dosage | Endonucleases - administration & dosage | Recombination, Genetic | Nanoparticles - metabolism | Molecular Structure | Genes, Reporter | Genetic Engineering - methods | Bacterial Proteins - genetics | Genes, Synthetic | Ceramides - chemistry | Lipids - administration & dosage | Gene Knockout Techniques | Static Electricity | Nanoparticles - toxicity | Bacterial Proteins - administration & dosage | Animals | Hypothalamus - metabolism | Lipids - chemical synthesis | Green Fluorescent Proteins - biosynthesis | CRISPR-Cas Systems | Luminescent Proteins - genetics | Mice | Nanoparticles - administration & dosage | HeLa Cells | Integrases - genetics | Phosphatidylethanolamines - chemistry | Nanoparticles | Genetic aspects | Nucleotide sequencing | Lipid metabolism | Health aspects | Methods | DNA sequencing | CRISPR | Physical Sciences | Cas9
Journal Article
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 15058
Precisely measuring the location and frequency of DNA double-strand breaks (DSBs) along the genome is instrumental to understanding genomic fragility, but... 
RECOMBINATION | SPECIFICITIES | CAS9 NUCLEASES | ENDONUCLEASES | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | OFF-TARGET CLEAVAGE | CPF1 | GAMMA-H2AX | CRISPR-CAS9 | SEQ
Journal Article