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Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 15, pp. 6814 - 6829
Polyamine derivatives have a promising prospect in dealing with disseminated tumor cells, a major obstacle in cancer therapy. To develop a bifunctional... 
SIDE-CHAINS | DESIGN | CHEMISTRY, MEDICINAL | F14512 | BIOLOGICAL EVALUATION | VECTORIZED ANTICANCER DRUG | OPTIMIZATION | MEDIATED APOPTOSIS | INHIBITORS | AUTOPHAGY | CANCER
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2007, Volume 30, Issue 9, pp. 1466 - 1476
Abstract Apoptosis has been identified as one of the important mechanisms involved in the degeneration of dopaminergic neurons in Parkinson's disease (PD). Our... 
Neurology | Internal Medicine | Divalent metal transporter 1 (DMT1) | Iron | Parkinson's disease | Iron regulatory protein (IRP) | Iron chelator | Apoptosis | IRON CONCENTRATION | SUBSTANTIA-NIGRA | TRANSITION-METALS | ASCORBIC-ACID | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | CYTOPLASMIC POOL | MESSENGER-RNA | TRANSFERRIN | HYDROGEN-PEROXIDE | RAT-BRAIN | PARKINSONS-DISEASE | Neurons - pathology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Caspase 3 - metabolism | Mitochondrial Diseases - metabolism | Nerve Degeneration - physiopathology | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Cation Transport Proteins - metabolism | Up-Regulation - physiology | Membrane Potential, Mitochondrial - physiology | Cation Transport Proteins - genetics | Neurons - metabolism | Parkinson Disease - metabolism | Neurons - drug effects | Cation Transport Proteins - drug effects | Mitochondrial Diseases - genetics | Gene Expression Regulation - genetics | Rats | Herbicides - toxicity | Parkinson Disease - physiopathology | Iron - metabolism | Up-Regulation - drug effects | Animals | 1-Methyl-4-phenylpyridinium - toxicity | Mice | Apoptosis - physiology | Cell Line, Transformed | Iron compounds | RNA | Analysis | Mitochondrial DNA | Blood proteins | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2006, Volume 99, Issue 3, pp. 868 - 880
Journal Article
Autophagy, ISSN 1554-8627, 2012, Volume 8, Issue 1, pp. 6 - 17
Beclin 1 (Atg6) is a well-known key regulator of autophagy. Although Beclin 1 is enzymatically inert, it governs the autophagic process by regulating... 
Bcl-2 | Membrane trafficking | Atg6 | Autophagy | Beclin 1 | BCL-X-L | APOPTOSIS | autophagy | AUTOPHAGY-RELATED PROTEIN | PHOSPHATIDYLINOSITOL 3-KINASE COMPLEXES | REGULATES AUTOPHAGY | MUTANT HUNTINGTIN | BH3 DOMAIN | CELL BIOLOGY | GENE | CASPASE-MEDIATED CLEAVAGE | MOLECULAR-BASIS | membrane trafficking
Journal Article
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 09/2011, Volume 243, Issue 1, pp. 206 - 214
Journal Article