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Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 451 - 462
Endoplasmic reticulum (ER) stress is observed in many human diseases, often associated with inflammation. ER stress can trigger inflammation through... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Caspase 2 - genetics | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Brucella abortus - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | BH3 Interacting Domain Death Agonist Protein - genetics | Caspase 2 - metabolism | Mitochondria - immunology | Endoplasmic Reticulum Stress - genetics | Endoplasmic Reticulum Stress - immunology | Caspase 2 - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Mitochondria - genetics | Brucella abortus - immunology | Interleukin-1beta - metabolism | Reactive Oxygen Species - immunology | HEK293 Cells | Transcription Factors - immunology | BH3 Interacting Domain Death Agonist Protein - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Protein-Serine-Threonine Kinases - metabolism | RNA Interference - immunology | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-1beta - immunology | Mitochondria - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Protein-Serine-Threonine Kinases - immunology | Endoribonucleases - immunology | Medical colleges | Stress (Physiology) | Mitochondrial DNA | Analysis | Cytochrome | Bacterial infections | Dehydrogenases | Infections | Inflammation | Proteins | Studies | Mitochondria | Rodents | Ligands | Endoplasmic reticulum | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 10/2011, Volume 166, Issue 1, pp. 1 - 15
Summary While interleukin (IL)‐1β plays an important role in combating the invading pathogen as part of the innate immune response, its dysregulation is... 
infections | NLRP3 | interleukin‐1 | innate immunity | inflammasome | Innate immunity | Interleukin-1 | Infections | Inflammasome | Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Enzyme Precursors - genetics | Gout - drug therapy | Mycoses - microbiology | Caspase 1 - metabolism | Virus Diseases - virology | Caspase 1 - immunology | Interleukin-1beta - genetics | Signal Transduction - immunology | Bacterial Infections - immunology | Inflammation - drug therapy | Interleukin-1beta - metabolism | Diabetes Mellitus, Type 2 - immunology | Gout - immunology | Hereditary Autoinflammatory Diseases - pathology | Bacterial Infections - microbiology | Carrier Proteins - immunology | Molecular Targeted Therapy - methods | Virus Diseases - immunology | Anti-Inflammatory Agents - pharmacology | Enzyme Precursors - immunology | Gene Expression Regulation | Hereditary Autoinflammatory Diseases - immunology | Interleukin-1beta - immunology | Mice, Transgenic | Inflammation - immunology | Immunity, Innate | Hereditary Autoinflammatory Diseases - drug therapy | Inflammasomes - genetics | Neoplasms - drug therapy | Carrier Proteins - genetics | Enzyme Precursors - metabolism | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | Gout - pathology | Neoplasms - immunology | Inflammasomes - immunology | Mice | Diabetes Mellitus, Type 2 - pathology | Enzyme Activation | Diabetes Mellitus, Type 2 - drug therapy | Neoplasms - pathology | Mycoses - immunology | Medical research | Immune system | Index Medicus | Infection | Pathogens | Immune response | Diabetes mellitus | Gout | Interleukin 1 | Cancer | Caspase-1 | interleukin-1 | Review
Journal Article
Immunologic research, ISSN 1559-0755, 08/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | Life Sciences & Biomedicine | Science & Technology | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | Index Medicus | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 09/2009, Volume 284, Issue 36, pp. 24035 - 24048
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Toll-Like Receptor 2 - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Immunity, Innate - genetics | Extracellular Matrix - metabolism | Caspase 1 - metabolism | Male | Ureteral Obstruction - metabolism | Interleukin-1beta - genetics | Inflammation - metabolism | Kidney - metabolism | Carrier Proteins - immunology | Signal Transduction | Proteoglycans - immunology | Extracellular Matrix Proteins - genetics | Proteoglycans - metabolism | Toll-Like Receptor 4 - genetics | Biglycan | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Ureteral Obstruction - immunology | Macrophages - metabolism | Receptors, Purinergic P2 - metabolism | Toll-Like Receptor 2 - immunology | Mice | Proteoglycans - genetics | Extracellular Matrix - immunology | Kidney - immunology | Caspase 1 - immunology | Extracellular Matrix - genetics | Receptors, Purinergic P2 - genetics | Ureteral Obstruction - genetics | Interleukin-1beta - biosynthesis | Lung - metabolism | Receptors, Purinergic P2 - immunology | Extracellular Matrix Proteins - metabolism | Macrophages - immunology | Carrier Proteins - biosynthesis | Interleukin-1beta - immunology | Inflammation - immunology | Protein Structure, Tertiary - genetics | Receptors, Purinergic P2X7 | Carrier Proteins - genetics | Immunity, Innate - immunology | Animals | Caspase 1 - genetics | Extracellular Matrix Proteins - immunology | Receptors, Purinergic P2X4 | Inflammation - genetics | Lung - immunology | Animal models | Reactive oxygen species | Oligomerization | Proteoglycans | Transcription | Lung | Inflammation | Macrophages | Kidney | Stress | Caspase-1 | Purine P2X receptors | Signal transduction | Cell activation | TLR2 protein | Interleukin 1 | Toll-like receptors | Extracellular matrix | Sepsis | Cooperativity | Injuries | Index Medicus | Glycobiology and Extracellular Matrices
Journal Article
PloS one, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121393 - e0121393
...) major allergen, Der p 2, can induce proinflammatory cytokine production which contributes to airway inflammation and allergic asthma... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Leukocytes, Mononuclear - metabolism | Eosinophils - metabolism | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Caspase 1 - immunology | Eosinophils - immunology | CD4-Positive T-Lymphocytes - immunology | Antigens, Dermatophagoides - immunology | Interleukin-1beta - metabolism | Leukocytes, Mononuclear - immunology | Cell-Penetrating Peptides - immunology | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Interferon-alpha - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-1beta - immunology | Arthropod Proteins - immunology | Antigens, Dermatophagoides - metabolism | Interferon-alpha - immunology | Animals | Carrier Proteins - metabolism | Up-Regulation - immunology | Inflammasomes - immunology | Interleukin-6 - immunology | Arthropod Proteins - metabolism | Interleukin-8 - immunology | Cell-Penetrating Peptides - metabolism | Pyroglyphidae - immunology | Proteins | Allergens | Inflammation | Cytokines | Asthma | Peptides | Mites | Stimulation | Leukocytes (mononuclear) | Mitochondrial DNA | CD14 antigen | Autophagy | Caspase-1 | Respiratory tract | Interleukin 6 | α-Interferon | Cell activation | Immunology | Immunotherapy | Penicillin | Peripheral blood mononuclear cells | Respiratory tract diseases | Interleukin 8 | Medical research | Bacterial infections | Immunomodulation | Hypersensitivity | House dust | Rheumatology | Caspase | Allergies | Hospitals | Internalization | Cations | Eosinophil cationic protein | Phagocytosis | Index Medicus
Journal Article