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Journal of Biological Chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 48, pp. 33394 - 33405
Micro-RNAs are similar to 21-25-nucleotide-long noncoding RNAs that regulate gene expression primarily at the post-transcriptional level in animals. Here, we... 
SURVIVAL | C/EBP-ALPHA | MICRORNA FUNCTION | THERAPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | TUMOR-SUPPRESSOR | TARGETS | DEGRADATION | HUMAN HEPATOCELLULAR CARCINOMAS | EXPRESSION | Lung Neoplasms - drug therapy | Histone Deacetylases - biosynthesis | Antibiotics, Antineoplastic - pharmacology | Caspase 7 - biosynthesis | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | MicroRNAs - metabolism | Proto-Oncogene Proteins - biosynthesis | RNA, Neoplasm - metabolism | Receptors, Growth Factor - genetics | Caspase 3 - genetics | Caspase 3 - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - genetics | Forkhead Transcription Factors - biosynthesis | Histone Deacetylases - genetics | Caspase 7 - genetics | Cell Survival | Proto-Oncogene Proteins c-met | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Poly(ADP-ribose) Polymerases - biosynthesis | Down-Regulation - drug effects | Forkhead Transcription Factors - genetics | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Down-Regulation - genetics | Animals | Poly(ADP-ribose) Polymerases - genetics | Repressor Proteins - biosynthesis | Mice, Nude | Myeloid Cell Leukemia Sequence 1 Protein | Receptors, Growth Factor - biosynthesis | Cell Line, Tumor | Proto-Oncogene Proteins c-pim-1 - genetics | RNA, Neoplasm - genetics | Mice | MicroRNAs - genetics | Poly (ADP-Ribose) Polymerase-1 | Proto-Oncogene Proteins c-bcl-2 - genetics | Proto-Oncogene Proteins c-pim-1 - biosynthesis | Doxorubicin - pharmacology | Cell Movement | RNA-Mediated Regulation and Noncoding Rnas
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 06/2013, Volume 1832, Issue 6, pp. 848 - 863
Sepsis is characterized by systematic inflammation and contributes to cardiac dysfunction. This study was designed to examine the effect of protein kinase B... 
Heart | ER stress | Sepsis | Akt | Contractile function | Apoptosis | OXIDATIVE STRESS | CONTRACTILE DYSFUNCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | ENDOPLASMIC-RETICULUM STRESS | AUTOPHAGY | GROWTH-FACTOR I | SIGNAL-TRANSDUCTION | SYNTHASE | BIOPHYSICS | INFLAMMATORY RESPONSE | NF-KAPPA-B | Caspase 9 - genetics | Apoptosis - drug effects | Calcium - metabolism | Heat-Shock Proteins - biosynthesis | Myocardial Contraction - drug effects | bcl-2-Associated X Protein - biosynthesis | Apoptosis - genetics | Glycogen Synthase Kinase 3 beta | Heat-Shock Proteins - genetics | Phosphorylation - genetics | Caspase 3 - genetics | Phosphorylation - drug effects | Transcription Factor CHOP - biosynthesis | Proto-Oncogene Proteins c-akt - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Lipopolysaccharides - toxicity | Endoplasmic Reticulum Stress - drug effects | Mice, Transgenic | Glycogen Synthase Kinase 3 - genetics | Eukaryotic Initiation Factor-2 - genetics | Mice | Enzyme Activation - genetics | Transcription Factor CHOP - genetics | Eukaryotic Initiation Factor-2 - biosynthesis | Microtubule-Associated Proteins - genetics | bcl-X Protein - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Endoplasmic Reticulum Stress - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Myocardial Contraction - genetics | MAP Kinase Signaling System - genetics | Apoptosis Regulatory Proteins - genetics | Caspase 3 - biosynthesis | bcl-X Protein - biosynthesis | bcl-2-Associated X Protein - genetics | Beclin-1 | Gene Expression Regulation - genetics | Myocardium - pathology | Transcription Factors - biosynthesis | Transcription Factors - genetics | Enzyme Activation - drug effects | Glycogen Synthase Kinase 3 - metabolism | Microtubule-Associated Proteins - biosynthesis | Gene Expression Regulation - drug effects | Autophagy-Related Protein 7 | Myocardium - enzymology | Animals | MAP Kinase Signaling System - drug effects | Caspase 9 - biosynthesis
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2012, Volume 131, Issue 1, pp. 30 - 40
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 08/2016, Volume 304, pp. 59 - 69
Honokiol, an active constituent extracted from the bark of , possesses anticancer effects. Apoptosis is classified as type I programmed cell death, while... 
Honokiol | Malignant glioma | Autophagy | ROS | p53/PI3K/Akt/mTOR | APOPTOSIS | GLIOBLASTOMA-MULTIFORME | PROTEIN-KINASE | DNA-DAMAGE | CYCLE ARREST | P53 | BREAST-CANCER | IN-VITRO | INHIBITION | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Reactive Oxygen Species - metabolism | Tumor Suppressor Protein p53 - biosynthesis | Apoptosis - drug effects | Microtubule-Associated Proteins - drug effects | Autophagy - drug effects | Biphenyl Compounds - toxicity | Dose-Response Relationship, Drug | Lignans - toxicity | Time Factors | Phosphatidylinositol 3-Kinases - drug effects | RNA, Small Interfering - biosynthesis | Caspase 3 - drug effects | Caspase 3 - biosynthesis | TOR Serine-Threonine Kinases - biosynthesis | Phosphatidylinositol 3-Kinases - biosynthesis | TOR Serine-Threonine Kinases - drug effects | Adenine - analogs & derivatives | Signal Transduction | Down-Regulation | Adenine - pharmacology | Microtubule-Associated Proteins - biosynthesis | Sirolimus - pharmacology | Tumor Suppressor Protein p53 - drug effects | Proto-Oncogene Proteins c-akt - biosynthesis | Animals | Ascorbic Acid - pharmacology | Cell Line, Tumor | Mice | Glioma - drug therapy | Proto-Oncogene Proteins c-akt - drug effects | Biochemistry | Tumor proteins | Gliomas | Cell death | Index Medicus | GLIOMAS | ANTIOXIDANTS | RNA | IN VIVO | 60 APPLIED LIFE SCIENCES | ASCORBIC ACID | CONCENTRATION RATIO | ABUNDANCE | IN VITRO | CELL CYCLE | MICE | PROTEINS | TIME DEPENDENCE
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2013, Volume 65, pp. 1435 - 1446
Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of the insulin signaling pathway and is considered a promising therapeutic target in the... 
PTP1B | Mitochondrial dysfunction | Free radicals | Palmitate | Apoptosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELLS | DOWN-REGULATION | FACTOR-KAPPA-B | ENDOPLASMIC-RETICULUM STRESS | INSULIN SENSITIVITY | DAMAGE | FATTY-ACID OXIDATION | ENDOCRINOLOGY & METABOLISM | HUMAN OBESITY | EXPRESSION | Phosphorylation | Reactive Oxygen Species | Humans | Apoptosis - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Muscle Fibers, Skeletal - metabolism | Adenosine Triphosphate - biosynthesis | Muscle, Skeletal - cytology | Sirtuin 1 - genetics | Nuclear Respiratory Factor 1 - biosynthesis | Forkhead Transcription Factors - metabolism | Palmitates - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Caspase 3 - biosynthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Active Transport, Cell Nucleus | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Cell Survival | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Sirtuin 1 - biosynthesis | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondrial Proteins - biosynthesis | Insulin - metabolism | Sphingosine - analogs & derivatives | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Caspase 9 - biosynthesis | Forkhead Box Protein O1 | Apoptosis - physiology | DNA-Binding Proteins - biosynthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - biosynthesis | Sphingosine - chemistry | Tyrosine | Muscles | Phenols | Phosphatases | Diabetes | Free radicals (Chemistry)
Journal Article
Journal of Virology, ISSN 0022-538X, 10/2012, Volume 86, Issue 20, pp. 10961 - 10978
Journal Article