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Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 1, pp. 221 - 230.e3
Background & Aims Anti–tumor necrosis factor (TNF)α antibodies are effective in treating patients with Crohn's disease whereas soluble TNFα receptors have not... 
Gastroenterology and Hepatology | Autoimmunity | IBD | Inflammatory Response | Type 2 Macrophage | MONOCLONAL-ANTIBODY | POLYMORPHISM | ACTIVE CROHNS-DISEASE | INFLAMMATORY-BOWEL-DISEASE | ACCENT-I | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | TNF-ALPHA | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | T-LYMPHOCYTES | Cell Proliferation | Certolizumab Pegol | Humans | Lectins, C-Type - immunology | Anti-Inflammatory Agents - immunology | Caspase 3 - immunology | Antibodies, Monoclonal, Humanized | Lymphocyte Activation - immunology | Immunoglobulin Fc Fragments - immunology | Etanercept | Infliximab | Immunoglobulin G - immunology | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Immunosuppressive Agents - pharmacology | Antibodies, Monoclonal - immunology | Macrophages - immunology | Cytokines - immunology | Polyethylene Glycols - pharmacology | Leukocytes, Mononuclear - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Cytokines - secretion | Crohn Disease - immunology | Receptors, Cell Surface - immunology | Immunoglobulin Fab Fragments - pharmacology | Mannose-Binding Lectins - immunology | Receptors, Fc - immunology | Immunosuppressive Agents - immunology | Lymphocyte Activation - drug effects | Caspase 3 - analysis | T-Lymphocytes - immunology | Immunoglobulin Fab Fragments - immunology | Adalimumab | Receptors, Tumor Necrosis Factor - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Apoptosis
Journal Article
Immunologic Research, ISSN 0257-277X, 10/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4640 - 4649
Dendritic cells (DC) are professional APCs that regulate innate and adaptive immunity. The role of fatty-acid synthesis in DC development and function is... 
CANCER-CELLS | APOPTOSIS | KAPPA-B ACTIVATION | UNFOLDED PROTEIN RESPONSE | CYTOKINE PRODUCTION | SYNTHASE INHIBITION | ER STRESS | MAP KINASE | MACROPHAGES | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | Fatty Acids - immunology | Leukocytes, Mononuclear - metabolism | Chemokine CCL2 - immunology | Dendritic Cells - immunology | Humans | Caspase 3 - metabolism | Male | Cyclin B1 - metabolism | Interferon-gamma - metabolism | PPAR gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Mitogen-Activated Protein Kinase Kinases - metabolism | Liver - immunology | CD8-Positive T-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Interleukin-12 - metabolism | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Intercellular Adhesion Molecule-1 - metabolism | Proto-Oncogene Proteins c-akt - immunology | T-Lymphocytes, Cytotoxic - metabolism | Endoplasmic Reticulum - immunology | Interleukin-12 - immunology | Mice | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | bcl-X Protein - metabolism | Fatty Acids - biosynthesis | Mitogen-Activated Protein Kinase Kinases - immunology | Caspase 3 - immunology | Endoplasmic Reticulum - metabolism | Genes, MHC Class II - immunology | PPAR gamma - immunology | Cyclin B1 - immunology | Leukocytes, Mononuclear - immunology | bcl-X Protein - immunology | Killer Cells, Natural - immunology | Chemokine CCL2 - metabolism | B7-2 Antigen - immunology | Fatty Acids - metabolism | Dendritic Cells - metabolism | T-Lymphocytes, Cytotoxic - immunology | B7-1 Antigen - immunology | Intercellular Adhesion Molecule-1 - immunology | Mice, Inbred C57BL | B7-1 Antigen - metabolism | Animals | Apoptosis - immunology | Interferon-gamma - immunology | Dendritic Cells - cytology | Fatty-acid synthesis | ER stress | NK cells | T cells | Bone marrow dendritic cells
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 84, Issue 1, pp. 172 - 186
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4846 - 10
Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this... 
A-INDUCED APOPTOSIS | ACTIVATION | TOXIN-B | GASDERMIN D | COMMON POLYMORPHISM | MULTIDISCIPLINARY SCIENCES | INFLAMMASOME | GLUCOSYLATION | PYROPTOSIS | RHO-GTPASES | INTERLEUKIN-8 GENE PROMOTER | Organoids - microbiology | Clostridium difficile - immunology | Humans | Caspase 3 - immunology | Pyrin - genetics | Enterocolitis, Pseudomembranous - microbiology | Host-Pathogen Interactions - immunology | Enterotoxins - immunology | Intestinal Mucosa - immunology | Enterocolitis, Pseudomembranous - immunology | Pyrin - immunology | Caspase 3 - genetics | Bacterial Toxins - genetics | Bacterial Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Disease Models, Animal | Signal Transduction | Caspase 7 - genetics | Bacterial Toxins - immunology | Mice, Inbred C57BL | Bacterial Proteins - genetics | Enterocolitis, Pseudomembranous - genetics | Gene Expression Regulation | Intestinal Mucosa - microbiology | Immunity, Innate | Inflammasomes - genetics | Mice, Knockout | Enterotoxins - genetics | Animals | Apoptosis - immunology | Epithelial Cells - immunology | Epithelial Cells - microbiology | Inflammasomes - immunology | Clostridium difficile - growth & development | Mice | Organoids - immunology | Caspase 7 - immunology | Cytotoxicity, Immunologic | Pathogenesis | Epithelial cells | Enterotoxins | Caspase | Cytotoxicity | Infections | Inflammation | Macrophages | Caspase-3 | Inflammatory bowel disease | Pyrin protein | Intestine | Bacteria | In vivo methods and tests | Colon | Colitis | Pseudomembranous colitis | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0166891
Background Approximately fifty percent of patients with acute myeloid leukemia can be cured with current therapeutic strategies which include, standard dose... 
GEMTUZUMAB OZOGAMICIN | PHARMACOKINETICS | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN | DEATH | ON-TARGET | CASPASE-9 | INDUCED KILLER-CELLS | SAFETY SWITCH | LYMPHOCYTES | Recombinant Fusion Proteins - immunology | Cyclophosphamide - analogs & derivatives | Caspase 9 - genetics | Humans | Sialic Acid Binding Ig-like Lectin 3 - immunology | Leukemia, Myeloid, Acute - immunology | Cellular Reprogramming | Biphenyl Compounds - pharmacology | Lysosomal-Associated Membrane Protein 1 - genetics | Nitrophenols - pharmacology | Myeloid Cells - immunology | T-Lymphocytes - drug effects | Lysosomal-Associated Membrane Protein 1 - immunology | Tumor Necrosis Factor-alpha - immunology | Myeloid Cells - drug effects | Receptors, Antigen, T-Cell - immunology | Leukemia, Myeloid, Acute - therapy | Sialic Acid Binding Ig-like Lectin 3 - genetics | Leukemia, Myeloid, Acute - pathology | Clinical Trials as Topic | Sulfonamides - pharmacology | Piperazines - pharmacology | Caspase 9 - immunology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | T-Lymphocytes - cytology | B7-H1 Antigen - pharmacology | Cyclophosphamide - pharmacology | Interferon-gamma - immunology | Sialic Acid Binding Ig-like Lectin 3 - antagonists & inhibitors | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Cell Engineering | T-Lymphocytes - immunology | Cell Proliferation - drug effects | Receptors, Antigen, T-Cell - genetics | Myeloid Cells - pathology | Primary Cell Culture | Genetic Vectors | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - biosynthesis | Cytotoxicity, Immunologic | Leukemia, Myeloid, Acute - genetics | Usage | Transplantation | Research | T cells | Immunotherapy | Stem cells | Transplants & implants | Bcl-2 protein | Leukemia | Mental health | Oncology | Standard error | Lymphocytes T | Suicide | Hematopoietic stem cells | Infusion | Immunology | Granulocytes | Lymphocytes | Drug dosages | Genetic modification | Suicide genes | Antigens | Cytokines | Risk groups | Hematology | Myeloid leukemia | Safety measures | Risk reduction | T cell receptors | Tumor necrosis factor-α | Patients | Hemopoiesis | Studies | Chemotherapy | Inhibitors | γ-Interferon | Degranulation | Antitumor activity | Ligands | Interferon | Gene therapy | Acute myeloid leukemia | Cancer | Apoptosis
Journal Article