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PloS one, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e96239 - e96239
...-Oncology, Departments of Neurology, Microbiology, and Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia, United... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplastic Stem Cells - cytology | Caspase 9 - genetics | Caspase 9 - metabolism | Humans | Caspase 3 - metabolism | Gene Expression Regulation, Neoplastic | Glycoproteins - metabolism | Peptides - genetics | 3' Untranslated Regions - genetics | Cell Survival - genetics | MicroRNAs - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Flow Cytometry | Peptides - metabolism | Bcl-2-Like Protein 11 | Glioblastoma - genetics | Neoplastic Stem Cells - metabolism | Caspase 3 - genetics | Apoptosis Regulatory Proteins - genetics | Glioblastoma - metabolism | Membrane Proteins - metabolism | Cell Survival - physiology | Glycoproteins - genetics | Proto-Oncogene Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | Proto-Oncogene Proteins - genetics | AC133 Antigen | Apoptosis Regulatory Proteins - metabolism | Cell Line, Tumor | MicroRNAs - genetics | DNA microarrays | MicroRNA | Analysis | Luciferase | Stem cells | Glioblastoma multiforme | Apoptosis | Brain | Flow cytometry | Brain tumors | Brain cancer | Glioblastoma | Fluorescence | Oncology | Biochemistry | Neurosurgery | Caspase-3 | Cancer therapies | Genetics | miRNA | Cell survival | Caspase | siRNA | Ribonucleic acid--RNA | Survival | Neurology | Brain research | Mutagenesis | 3' Untranslated regions | Cell number | MicroRNAs | Caspase-9 | Neural stem cells | Annexin V | BIM protein | Cancer | Tumors | Index Medicus | RNA | Ribonucleic acid
Journal Article
by Pattaro, Cristian and Köttgen, Anna and Teumer, Alexander and Böger, Carsten and Fuchsberger, Christian and Olden, Matthias and Chen, Ming-Huei and Li, Man and Gao, Xiaoyi and Gorski, Mathias and Yang, Qiong Fang and O'Seaghdha, Conall and Glazer, Nicole and Isaacs, Aaron and Liu, Ching-Ti and Smith, Albert Vernon and O´Connell, J.R and Struchalin, Maksim and Tanaka, Toshiko and Johnson, Anew and Feitosa, Mary Furlan and Hwang, S.J and Lohman, Kurt and Cornelis, Marilyn and Johansson, Åsa and Tönjes, Anke and Dehghan, Abbas and Chouraki, Vincent and Holliday, Elizabeth and Sorice, R and Kutalik, Zoltán and Lehtimäki, Terho and Esko, Tõnu and Ulivi, Shelia and Trompet, Stella and Imboden, Medea and Kollerits, Barbara and Pistis, Giorgio and Harris, Tamara and Launer, Lenore and Aspelund, Thor and Eiriksdottir, Gudny and Mitchell, Braxton and Boerwinkle, Eric and Schmidt, Reinhold and Cavalieri, Margherita and Hu, Frank and Demirkan, Ayşe and Oostra, Ben and Anade, Mariza and Anews, Jeanette and Koenig, Wolfgang and Illig, Thomas and Döring, Angela and Wichmann, Erich and Kolcic, Ivana and Zemunik, Tatijana and Boban, Mladen and Igl, Wilmar and Zaboli, Ghazal and Wild, Sarah and Wright, Alan and Campbell, Harry and Biffar, Reiner and Ernst, Florian and Homuth, Georg and Kroemer, Heyo and Nauck, Matthias and Kovacs, Peter and Stumvoll, Michael and Mägi, Reedik and Hofman, Albert and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and Aulchenko, Yurii and Polasek, Ozren and Hastie, Nick and Vitart, Veronique and Wang, Jie Jin and Bergmann, Sven and Kähönen, Mika and Viikari, Jorma and Province, Mike and Ketkar, Shamika and Doney, Alex and Ford, Ian and Buckley, Brendan M and Paulweber, Bernhard and Haun, Margot and Sala, Cinzia and Ciullo, M and Vollenweider, Peter and Raitakari, Olli and Metspalu, Anes and Palmer, Colin and Gasparini, Paolo and Jukema, Jan Wouter and Kronenberg, Florian and Toniolo, Daniela and Gudnason, Vilmundur and ... and CARDIoGRAM Consortium and ICBP Consortium and WTCCC2 and CARe Consortium and Wellcome Trust Case Control Consortium 2 (WTCCC2)
PLoS genetics, ISSN 1553-7390, 03/2012, Volume 8, Issue 3, pp. e1002584 - e1002584
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 8027 - 8035
Bacterial LPS (endotoxin) is implicated in the pathogenesis of acute liver failure and several chronic inflammatory liver diseases. To evaluate the effect of... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Aspartate Aminotransferases - genetics | Caspase 9 - genetics | Caspase 9 - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Liver Failure, Acute - enzymology | Apoptosis - genetics | Alanine Transaminase - blood | Mitogen-Activated Protein Kinase 9 - genetics | Necrosis - immunology | Cyclooxygenase 2 - genetics | Hepatitis - genetics | Caspase 3 - genetics | Hepatitis - metabolism | Gene Expression | Hemorrhage - genetics | Lipopolysaccharides - toxicity | Mitogen-Activated Protein Kinase 9 - metabolism | Hemorrhage - immunology | Mice, Transgenic | Aspartate Aminotransferases - immunology | Signal Transduction - genetics | Caspase 9 - immunology | Aspartate Aminotransferases - blood | Signal Transduction - drug effects | Up-Regulation - immunology | Liver Failure, Acute - immunology | Liver Failure, Acute - pathology | Mice | Necrosis - genetics | Receptors, Prostaglandin E, EP1 Subtype | Chronic Disease | Galactosamine - toxicity | Hepatocytes - enzymology | Organ Specificity - drug effects | Poly(ADP-ribose) Polymerases - immunology | Caspase 3 - immunology | Hepatocytes - pathology | Necrosis - pathology | Receptors, Prostaglandin E - genetics | Organ Specificity - immunology | Organ Specificity - genetics | Signal Transduction - immunology | Alanine Transaminase - genetics | Liver Failure, Acute - genetics | Receptors, Prostaglandin E - immunology | Alanine Transaminase - immunology | Cyclooxygenase 2 - immunology | Transgenes - genetics | Hepatitis - pathology | Mitogen-Activated Protein Kinase 9 - immunology | Up-Regulation - genetics | Hepatocytes - immunology | Up-Regulation - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Animals | Apoptosis - immunology | Poly(ADP-ribose) Polymerases - genetics | Cyclooxygenase 2 - metabolism | Hemorrhage - enzymology | Hepatitis - immunology | Transgenes - immunology | Hemorrhage - pathology | Necrosis - enzymology | Receptors, Prostaglandin E - metabolism | Index Medicus | Abridged Index Medicus | Lipopolysaccharide | EP1 receptor | liver | acute hepatic failure | cyclooxygenase-2 | endotoxin
Journal Article
Molecular cancer research, ISSN 1557-3125, 05/2011, Volume 9, Issue 7, pp. 889 - 900
Journal Article
PloS one, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e82742 - e82742
.... We have genetically modified human T cells with a lentiviral vector to express a CD20-CAR containing both CD28 and CD137 co-stimulatory domains, a "suicide gene'' relying on inducible activation of caspase 9 (iC9... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | NIH 3T3 Cells | Immunotherapy, Adoptive - methods | Caspase 9 - genetics | Genes, Transgenic, Suicide | Jurkat Cells | Humans | Cells, Cultured | Lymphoma - immunology | Lymphoma - genetics | Treatment Outcome | Mice, SCID | T-Lymphocytes - transplantation | Mice, Knockout | Antigens, CD20 - genetics | Xenograft Model Antitumor Assays | Animals | Lymphoma - therapy | T-Lymphocytes - metabolism | Recombinant Fusion Proteins - genetics | Mice, Inbred NOD | Mice | Receptors, Antigen, T-Cell - genetics | Antigens | Care and treatment | Immunotherapy | Genetically modified organisms | Lymphomas | T cells | Gene therapy | Suicide | Cancer | Bioengineering | Transplants & implants | Toxicity | Leukemia | Adoptive immunotherapy | Clinical trials | Cytotoxicity | Lymphocytes T | CD28 antigen | Signal transduction | Receptors | Cell activation | Lymphocytes | Xenografts | Insertional mutagenesis | Genetic modification | Suicide genes | Medical research | CD19 antigen | CD137 antigen | Cytokines | Feasibility studies | Caspase | T cell receptors | Lymphoma | Medicine | Mutagenesis | Antigen-presenting cells | Stem cells | Caspase-9 | CD20 antigen | Tumors | Index Medicus | Activation
Journal Article