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JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 03/2012, Volume 104, Issue 6, pp. 476 - 487
Journal Article
International journal of cancer, ISSN 0020-7136, 01/2018, Volume 142, Issue 1, pp. 202 - 213
Journal Article
Cell death and differentiation, ISSN 1476-5403, 06/2014, Volume 21, Issue 10, pp. 1511 - 1521
Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1) and RIPK3 by receptors such as... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Kinases - metabolism | Protein Structure, Tertiary | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - metabolism | Cell Line | Phosphorylation | Protein Kinases - genetics | Cell Survival | Humans | Protein Multimerization | Receptors, Tumor Necrosis Factor, Type I | Caspase 8 - metabolism | Imidazoles - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Necrosis - physiopathology | RNA Interference | Indoles - pharmacology | RNA, Small Interfering | Apoptosis - physiology | Enzyme Activation | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Receptor-Interacting Protein Serine-Threonine Kinases/genetics | Protein Kinases/genetics | Receptor-Interacting Protein Serine-Threonine Kinases/antagonists & inhibitors | Caspase 8/metabolism | Receptor-Interacting Protein Serine-Threonine Kinases/metabolism | Tumor Necrosis Factor-alpha/antagonists & inhibitors | Indoles/pharmacology | Life Sciences | Tumor Necrosis Factor-alpha/metabolism | Imidazoles/pharmacology | Immunology | Apoptosis/physiology | Protein Kinases/metabolism | Necrosis/physiopathology | Original Paper
Journal Article
Cancer medicine (Malden, MA), ISSN 2045-7634, 11/2017, Volume 6, Issue 11, pp. 2646 - 2659
.... To investigate the effects of Akt inhibitors on MPM cell survival, we examined the effects of nine selective Akt inhibitors, namely, afuresertib, Akti... 
Afuresertib | cancer therapy | Mesothelioma | Akt inhibitor | Life Sciences & Biomedicine | Oncology | Science & Technology | Caspase 7 - metabolism | Apoptosis - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Humans | Caspase 3 - metabolism | Phosphorylcholine - analogs & derivatives | Heterocyclic Compounds, 4 or More Rings - pharmacology | Pleural Neoplasms - drug therapy | Quinoxalines - pharmacology | Oxadiazoles - pharmacology | Phosphorylcholine - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Pyrazoles - pharmacology | Thiadiazoles - pharmacology | Forkhead Box Protein O1 - metabolism | Thiophenes - pharmacology | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Glycogen Synthase Kinase 3 beta - metabolism | Mesothelioma - drug therapy | Pyrroles - pharmacology | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | G1 Phase Cell Cycle Checkpoints - drug effects | Benzylamines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Proteins | Analysis | Cell proliferation | Phosphorylation | Asbestos | Cell survival | Caspase | Cytotoxicity | Occupational diseases | AKT protein | Thorax | Myc protein | Cisplatin | Western blotting | 1-Phosphatidylinositol 3-kinase | Cyclin-dependent kinase inhibitor p21 | Cell number | Cell cycle | Forkhead protein | Apoptosis | G1 phase | Index Medicus
Journal Article
Clinical cancer research, ISSN 1557-3265, 05/2007, Volume 13, Issue 10, pp. 3024 - 3032
Journal Article
Oncogene, ISSN 0950-9232, 10/2006, Volume 25, Issue 47, pp. 6304 - 6318
Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs... 
Caspase | Indirubin | Cell death | Protein kinase | Autophagy | Cancer | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Caspases - physiology | Phosphorylation | Proto-Oncogene Proteins c-bcl-2 - physiology | Humans | Indoles - chemical synthesis | Male | Cell Line, Tumor - drug effects | Structure-Activity Relationship | Quinolines - pharmacology | Spodoptera | Tumor Suppressor Protein p53 - physiology | Recombinant Fusion Proteins - antagonists & inhibitors | Amino Acid Chloromethyl Ketones - pharmacology | Swine | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Indoles - pharmacology | Starfish | Cell Death - drug effects | Cyclin-Dependent Kinases - antagonists & inhibitors | STAT3 Transcription Factor - metabolism | Cell Line | CDC2 Protein Kinase - antagonists & inhibitors | Cell Line, Tumor - enzymology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Oximes - chemical synthesis | Cell Nucleus - ultrastructure | Oximes - chemistry | Animals | Cysteine Proteinase Inhibitors - pharmacology | bcl-X Protein - physiology | Oximes - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Protein Processing, Post-Translational | Cell Cycle - drug effects | Indoles - chemistry | Proteins | Inhibitor drugs | Kinases | Leukemia | Apoptosis | Index Medicus | Oximes | Quinolines | CDC2 Protein Kinase | Glycogen Synthase Kinase 3 | Recombinant Fusion Proteins | Life Sciences | Cell Death | Cyclin-Dependent Kinases | Indoles | bcl-X Protein | Cyclin-Dependent Kinase Inhibitor p21 | Biochemistry, Molecular Biology | Protein Kinase Inhibitors | Tumor Suppressor Protein p53 | Cell Cycle | Cysteine Proteinase Inhibitors | Amino Acid Chloromethyl Ketones | Cell Line, Tumor | STAT3 Transcription Factor | Proto-Oncogene Proteins c-bcl-2 | Caspases | Cell Nucleus
Journal Article
Journal Article