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The Journal of immunology (1950), ISSN 1550-6606, 04/2015, Volume 194, Issue 8, pp. 3829 - 3839
We have examined the molecular pathways involved in the adjuvant action of cholera toxin (CT) and two novel nontoxic molecules, multiple-mutated CT (mmCT) and... 
Life Sciences & Biomedicine | Immunology | Science & Technology | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | Adjuvants, Immunologic - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Interleukin-1beta - immunology | Male | Caspase 1 - immunology | Enzyme Activation - drug effects | Enzyme Activation - immunology | Signal Transduction - immunology | Signal Transduction - drug effects | Calcium-Binding Proteins - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Cyclic AMP - immunology | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - immunology | Th17 Cells - immunology | Adult | Female | Th17 Cells - cytology | Cholera Toxin - pharmacology | Carrier Proteins - immunology | Index Medicus | Abridged Index Medicus | Calcium-Binding Proteins/immunology | Signal Transducing/immunology | Apoptosis Regulatory Proteins/immunology | Cyclic AMP/ immunology | Enzyme Activation/drug effects/immunology | Adjuvants | Immunologi inom det medicinska området | Interleukin-1beta/ immunology | Adaptor Proteins | Th17 Cells/cytology/ immunology | Signal Transduction/ drug effects/immunology | Caspase 1/immunology | Carrier Proteins/immunology | Cholera Toxin/ pharmacology | Cyclic AMP-Dependent Protein Kinases/ immunology | CARD Signaling Adaptor Proteins/immunology | Immunologic/ pharmacology | Immunology in the medical area | Inflammasomes/ immunology
Journal Article
PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175153 - e0175153
IL-1 beta is a potent player in cutaneous inflammation and central for the development of a Th17 micro-milieu in autoinflammatory diseases including psoriasis.... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Caspases - immunology | Humans | Interleukin-17 - immunology | Interleukin-17 - pharmacology | Interleukin-1beta - genetics | S100 Proteins - immunology | Psoriasis - genetics | S100 Proteins - genetics | Th17 Cells - drug effects | Transfection | Inflammasomes - drug effects | Psoriasis - pathology | Adaptor Proteins, Signal Transducing - immunology | Apoptosis Regulatory Proteins - genetics | Skin - pathology | Skin - immunology | Th17 Cells - pathology | Interleukin-1beta - secretion | Psoriasis - immunology | S100 Calcium Binding Protein A7 | Apoptosis Regulatory Proteins - immunology | DNA - immunology | Signal Transduction | Caspases - genetics | Cells, Cultured | Gene Expression Regulation | Interleukin-17 - genetics | Interleukin-1beta - immunology | Vitamin D - pharmacology | Keratinocytes - cytology | Keratinocytes - immunology | DNA - genetics | Interleukin-17 - antagonists & inhibitors | Keratinocytes - drug effects | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - genetics | Th17 Cells - immunology | Interferon-gamma - pharmacology | Interleukins | Physiological aspects | Development and progression | Skin diseases | Genetic aspects | Inflammation | Research | Cell culture | Transcription | Interleukin | Helper cells | Lymphocytes T | Inflammatory diseases | Vitamin D | Lymphocytes | Interleukin 1 | Lesions | Deoxyribonucleic acid--DNA | Psoriasis | Cytokines | Dermatology | Keratinocytes | Caspase | Epidermis | Hazards | Gene expression | Caspase-5 | Hospitals | Biopsy | Interferon | Autoimmune diseases | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature immunology, ISSN 1529-2916, 04/2012, Volume 13, Issue 5, pp. 449 - 456
Intestinal phagocytes transport oral antigens and promote immune tolerance, but their role in innate immune responses remains unclear. Here we found that... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammasomes - metabolism | Humans | Receptors, Interleukin-1 - genetics | Salmonella Infections - genetics | Salmonella Infections - immunology | Clonal Anergy | Caspase 1 - metabolism | Monocytes - metabolism | Monocytes - immunology | Intestines - immunology | Host-Pathogen Interactions - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Apoptosis Regulatory Proteins - genetics | Pseudomonas - immunology | Toll-Like Receptors - metabolism | Neutrophil Infiltration - immunology | Neutrophils - pathology | Apoptosis Regulatory Proteins - immunology | Flagellin - immunology | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Neutrophils - immunology | Salmonella - genetics | Signal Transduction - genetics | Phagocytes - immunology | Neutrophil Infiltration - genetics | Mice, Knockout | Pseudomonas Infections - immunology | Salmonella - immunology | Animals | Intestines - microbiology | Phagocytes - microbiology | Inflammasomes - immunology | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Calcium-Binding Proteins - genetics | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2916, 06/2014, Volume 15, Issue 8, pp. 727 - 737
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 451 - 462
Endoplasmic reticulum (ER) stress is observed in many human diseases, often associated with inflammation. ER stress can trigger inflammation through... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Caspase 2 - genetics | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Brucella abortus - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | BH3 Interacting Domain Death Agonist Protein - genetics | Caspase 2 - metabolism | Mitochondria - immunology | Endoplasmic Reticulum Stress - genetics | Endoplasmic Reticulum Stress - immunology | Caspase 2 - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Mitochondria - genetics | Brucella abortus - immunology | Interleukin-1beta - metabolism | Reactive Oxygen Species - immunology | HEK293 Cells | Transcription Factors - immunology | BH3 Interacting Domain Death Agonist Protein - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Protein-Serine-Threonine Kinases - metabolism | RNA Interference - immunology | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-1beta - immunology | Mitochondria - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Protein-Serine-Threonine Kinases - immunology | Endoribonucleases - immunology | Medical colleges | Stress (Physiology) | Mitochondrial DNA | Analysis | Cytochrome | Bacterial infections | Dehydrogenases | Infections | Inflammation | Proteins | Studies | Mitochondria | Rodents | Ligands | Endoplasmic reticulum | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 03/2014, Volume 192, Issue 6, pp. 2837 - 2845
Inflammation is associated with development of atherosclerosis, and cholesterol crystals (CC) have long been recognized as a hallmark of atherosclerotic... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Complement C1q - immunology | Humans | Complement Pathway, Classical - drug effects | Complement C5a - metabolism | Complement System Proteins - immunology | Caspase 1 - metabolism | Monocytes - metabolism | Caspase 1 - immunology | Macrophage-1 Antigen - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Complement Activation - immunology | Complement C1q - metabolism | Complement System Proteins - metabolism | Inflammasomes - drug effects | Reactive Oxygen Species - immunology | Complement C5 - immunology | Tumor Necrosis Factor-alpha - immunology | Macrophage-1 Antigen - metabolism | Complement Activation - drug effects | Cytokines - immunology | Interleukin-1beta - secretion | Complement C5 - metabolism | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Cytokines - secretion | Phagocytosis - immunology | Interleukin-1beta - immunology | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Monocytes - drug effects | Complement Pathway, Classical - immunology | Microscopy, Confocal | Complement Pathway, Alternative - drug effects | Complement Pathway, Alternative - immunology | Inflammasomes - immunology | Cholesterol - pharmacology | Complement C5a - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Immunologic research, ISSN 1559-0755, 08/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | Life Sciences & Biomedicine | Science & Technology | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | Index Medicus | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article