X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (58840) 58840
Publication (6184) 6184
Book Review (3053) 3053
Book Chapter (242) 242
Conference Proceeding (181) 181
Dissertation (29) 29
Book / eBook (4) 4
Magazine Article (4) 4
Web Resource (4) 4
Data Set (3) 3
Government Document (3) 3
Paper (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (55438) 55438
apoptosis (39342) 39342
humans (35718) 35718
animals (31965) 31965
apoptosis - drug effects (23173) 23173
caspases - metabolism (20500) 20500
caspase 3 - metabolism (18207) 18207
mice (15251) 15251
biochemistry & molecular biology (12446) 12446
male (12108) 12108
cell line, tumor (11987) 11987
cell biology (11290) 11290
rats (10899) 10899
activation (10884) 10884
caspase (10720) 10720
female (9030) 9030
oncology (8910) 8910
caspase 3 (8841) 8841
expression (8517) 8517
apoptosis - physiology (7949) 7949
proteins (7928) 7928
cells, cultured (7459) 7459
oxidative stress (7445) 7445
death (7185) 7185
caspase-3 (7074) 7074
cancer (6977) 6977
signal transduction (6618) 6618
cell death (6269) 6269
cell survival - drug effects (6230) 6230
cell line (6088) 6088
mitochondria (5900) 5900
enzyme activation (5737) 5737
proto-oncogene proteins c-bcl-2 - metabolism (5625) 5625
cell-death (5408) 5408
blotting, western (5387) 5387
reactive oxygen species - metabolism (5356) 5356
mitochondria - metabolism (5197) 5197
neurosciences (5181) 5181
pharmacology & pharmacy (5117) 5117
cell proliferation - drug effects (5003) 5003
dose-response relationship, drug (4988) 4988
inhibition (4961) 4961
phosphorylation (4846) 4846
antineoplastic agents - pharmacology (4788) 4788
analysis (4720) 4720
signal transduction - drug effects (4554) 4554
in-vitro (4350) 4350
cells (4328) 4328
gene expression (4267) 4267
flow cytometry (4254) 4254
time factors (4207) 4207
caspase inhibitors (4166) 4166
rats, sprague-dawley (4116) 4116
research (4113) 4113
caspases (4081) 4081
enzyme activation - drug effects (4017) 4017
article (3714) 3714
mitochondria - drug effects (3705) 3705
inflammation (3635) 3635
cytochrome-c (3590) 3590
immunology (3533) 3533
bcl-2-associated x protein - metabolism (3520) 3520
disease models, animal (3496) 3496
cytochromes c - metabolism (3432) 3432
research article (3424) 3424
tumor cells, cultured (3416) 3416
mice, inbred c57bl (3382) 3382
nf-kappa-b (3364) 3364
rodents (3360) 3360
multidisciplinary sciences (3324) 3324
caspase 9 - metabolism (3289) 3289
dna fragmentation (3272) 3272
immunohistochemistry (3252) 3252
protein (3203) 3203
enzyme inhibitors - pharmacology (3191) 3191
in-vivo (3103) 3103
kinases (3003) 3003
medicine (2992) 2992
toxicology (2973) 2973
cell cycle (2971) 2971
bcl-2 (2960) 2960
apoptosis - genetics (2956) 2956
cell proliferation (2948) 2948
transfection (2916) 2916
induced apoptosis (2914) 2914
caspase 8 - metabolism (2881) 2881
in situ nick-end labeling (2860) 2860
induction (2848) 2848
physiological aspects (2811) 2811
cell survival (2795) 2795
biochemistry (2781) 2781
medicine, research & experimental (2775) 2775
health aspects (2774) 2774
poly polymerases - metabolism (2765) 2765
pathway (2657) 2657
cytotoxicity (2642) 2642
cytochrome c (2633) 2633
membrane potential, mitochondrial - drug effects (2602) 2602
biology (2565) 2565
mechanisms (2553) 2553
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (57410) 57410
Chinese (1227) 1227
Russian (94) 94
Japanese (65) 65
Polish (29) 29
French (28) 28
German (18) 18
Spanish (13) 13
Ukrainian (9) 9
Portuguese (6) 6
Hungarian (4) 4
Korean (3) 3
Lithuanian (2) 2
Slovak (2) 2
Czech (1) 1
Danish (1) 1
Finnish (1) 1
Hebrew (1) 1
Italian (1) 1
Romanian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Immunity, ISSN 1074-7613, 05/2013, Volume 38, Issue 5, pp. 1038 - 1049
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 23, pp. 5438 - 5458
Abstract Oxidative stress is a major component of harmful cascades activated in neurodegenerative disorders. We sought to elucidate possible effects of... 
Advanced Basic Science | Dentistry | Oxidative stress | Mitochondria | Caspase-dependent apoptosis | Endoplasmic reticulum | Alginate oligosaccharide | PC12 cells | SIGNALING PATHWAYS | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | CASCADES | P53 | DISEASES | BAX | CYTOCHROME-C RELEASE | PROTEINS | BINDING | MEMBRANE PERMEABILIZATION | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Calcium - metabolism | Glutathione - metabolism | Amyloid beta-Peptides - pharmacology | Oxidative Stress - physiology | Caspase 3 - metabolism | Endoplasmic Reticulum - metabolism | NF-kappa B - metabolism | Neurons - cytology | Peptide Fragments - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | PC12 Cells | Oligosaccharides - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Apoptosis Inducing Factor - pharmacology | Cell Nucleus - metabolism | Endoplasmic Reticulum - drug effects | Oxidation-Reduction - drug effects | Neurons - metabolism | Phosphorylation - drug effects | Glucuronic Acid - chemistry | Neurons - drug effects | Polysaccharide-Lyases - chemistry | Apoptosis Inducing Factor - metabolism | Cell Survival - drug effects | Cytochromes c - metabolism | Hydrogen Peroxide - pharmacology | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | Rats | Mitochondria - metabolism | Caspase 12 - metabolism | Hexuronic Acids - chemistry | Mitochondria - drug effects | HSP70 Heat-Shock Proteins - metabolism | Cell Shape - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Animals | Models, Biological | Alginates - chemistry | NF-E2-Related Factor 2 - metabolism | HSP90 Heat-Shock Proteins - metabolism | Apoptosis - physiology | Oxidative Stress - drug effects | Cell Nucleus - drug effects | Neurosciences | Nervous system diseases | Biological products | Hydrogen peroxide | Heat shock proteins | Nerve growth factor | Superoxide | Mitochondrial DNA | Biochemistry | Antioxidants | Tumor proteins | Protein kinases | Alzheimer's disease | Apoptosis | Stresses | Surgical implants | Biomedical materials | Cell death | Cascades | Blocking | Activation | Kinases | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2011, Volume 186, Issue 11, pp. 6553 - 6561
Journal Article
Laboratory Investigation, ISSN 0023-6837, 05/2012, Volume 92, Issue 5, pp. 713 - 723
Non-alcoholic steatohepatitis (NASH) is typically associated with pro-apoptotic caspase activation. A potential role for pro-inflammatory caspases remains... 
Inflammasome | Inflammation | Caspases | Non-alcoholic fatty liver disease | Non-alcoholic steatohepatitis | Fibrosis | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | APOPTOSIS | non-alcoholic fatty liver disease | MICE DEFICIENT | FATTY LIVER-DISEASE | INJURY | NONALCOHOLIC STEATOHEPATITIS | MODEL | PATHOLOGY | inflammation | inflammasome | fibrosis | caspases | HEPATIC STEATOSIS | non-alcoholic steatohepatitis | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Clodronic Acid - pharmacology | Fatty Liver - pathology | Actins - metabolism | Caspase 3 - metabolism | Hepatic Stellate Cells - metabolism | Caspase 1 - metabolism | Choline Deficiency - complications | Hepatocytes - pathology | Hepatocytes - metabolism | Fatty Liver - chemically induced | LIM Domain Proteins - metabolism | Liver Cirrhosis - chemically induced | Inflammation - metabolism | Caspase 3 - blood | Interleukin-1beta - metabolism | Choline Deficiency - metabolism | Liver Cirrhosis - metabolism | Muscle Proteins - metabolism | Antigens, Differentiation - metabolism | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Methionine - deficiency | Collagen Type I - metabolism | Fatty Liver - metabolism | Liver - metabolism | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Choline Deficiency - pathology | Kupffer Cells - drug effects | Mice, Knockout | Animals | Caspase 1 - genetics | Caspase 1 - deficiency | Liver Cirrhosis - pathology | Mice | Transforming Growth Factor beta - metabolism | Index Medicus | Nonalcoholic fatty liver disease (NAFLD) | nonalcoholic steatohepatitis (NASH)
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, pp. e0130624 - e0130624
Neuroinflammation is the local reaction of the brain to infection, trauma, toxic molecules or protein aggregates. The brain resident macrophages, microglia,... 
INTERLEUKIN-1 | ACTIVATION | MOLECULAR PLATFORM | INHIBITION | DISTINCT PATHWAYS | NEUROINFLAMMATION | MULTIDISCIPLINARY SCIENCES | IL-1-BETA | MECHANISMS | RECEPTORS | NALP3 INFLAMMASOME | Microglia - metabolism | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Peptide Fragments - toxicity | Caspase 1 - metabolism | Interleukin-1alpha - metabolism | alpha-Synuclein - pharmacology | Interleukin-1beta - metabolism | Interleukin-1beta - secretion | Microglia - cytology | Brain - cytology | Interleukin-1beta - analysis | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Amyloid beta-Peptides - toxicity | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | Caspase 1 - deficiency | Receptors, Purinergic P2X7 - metabolism | Mice | Interleukin-18 - metabolism | Astrocytes - metabolism | Cytokines | Health aspects | Nervous system diseases | Brain | Cell culture | Traumatic brain injury | Peptides | Aluminum sulfate | Homeostasis | Nervous system | Activation | Macrophages | Synuclein | Proteins | Rodents | Amyloid | Life sciences | Communication | Neurodegenerative diseases | Secretion | Astrocytes | Inflammation | Trauma | Molecular chains | Microglia | Interleukin 18 | Mode of action | Neurological diseases | Immune systems | Nigericin | Brain research | Ligands | Alum | Laboratory animals | Alzheimers disease | Chemokines | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2006, Volume 281, Issue 11, pp. 7260 - 7270
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7340, pp. 637 - 641
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 79 - 88
Despite great interest in cancer chemoprevention, effective agents are few. Here we show that chloroquine, a drug that activates the stress-responsive Atm-p53... 
MEDICINE, RESEARCH & EXPERIMENTAL | BCL-X-L | SIGNALING PATHWAYS | INDUCED APOPTOSIS | PHOSPHORYLATION | ATM | AUTOPHAGY | CYTOCHROME-C RELEASE | MYC-INDUCED LYMPHOMAGENESIS | TRANSGENIC MICE | P53 | Apoptosis - drug effects | Humans | Apoptosis - genetics | Male | Autophagy - drug effects | Burkitt Lymphoma - pathology | Neoplasms, Experimental - pathology | Chloroquine - pharmacology | Cell Transformation, Neoplastic - genetics | Autophagy - genetics | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Tumor Suppressor Proteins - metabolism | Embryo, Mammalian - pathology | Cell Cycle Proteins - metabolism | Neoplasms, Experimental - prevention & control | bcl-2-Associated X Protein - metabolism | Ataxia Telangiectasia Mutated Proteins | Fibroblasts - pathology | Ataxia Telangiectasia - pathology | Ataxia Telangiectasia - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Neoplasms, Experimental - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Embryo, Mammalian - metabolism | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Caspases - metabolism | Lysosomes - metabolism | Burkitt Lymphoma - prevention & control | Mice, Mutant Strains | Tumor Suppressor Proteins - genetics | Neoplasms, Experimental - genetics | Burkitt Lymphoma - genetics | Cell Cycle Proteins - genetics | Female | Lysosomes - pathology | Antirheumatic Agents - pharmacology | bcl-2-Associated X Protein - genetics | Antirheumatic Agents - therapeutic use | Ataxia Telangiectasia - prevention & control | Caspases - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Burkitt Lymphoma - metabolism | Chloroquine - therapeutic use | Ataxia Telangiectasia - metabolism | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Animals | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Cell Transformation, Neoplastic - pathology | Prevention | Chloroquine | Lysosomes | Dosage and administration | Research | Drug therapy | Health aspects | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 02/2003, Volume 23, Issue 4, pp. 1428 - 1440
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0136822 - e0136822
Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The... 
AMINO-ACID-METABOLISM | OXIDATIVE STRESS | DNA METHYLATION | LIQUID-CHROMATOGRAPHY | NITRIC-OXIDE SYNTHASE | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | FOLLOW-UP | STEATOHEPATITIS | ONE-CARBON METABOLISM | MASS-SPECTROMETRY | Glycine N-Methyltransferase - metabolism | Blood Chemical Analysis | Homocysteine - metabolism | Glutathione - biosynthesis | Diet, High-Fat | Female | Metabolic Networks and Pathways - physiology | Cysteine - metabolism | Dipeptides - metabolism | Betaine-Homocysteine S-Methyltransferase - metabolism | Acyl Coenzyme A - metabolism | B-Lymphocytes - metabolism | Methionine - metabolism | Liver - metabolism | Mice, Inbred C57BL | Metabolome | Adenosylhomocysteinase - metabolism | Methionine Adenosyltransferase - metabolism | DNA Methylation - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Cystathionine beta-Synthase - metabolism | Random Allocation | Animals | 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - metabolism | Mice | Fatty liver | Physiological aspects | Development and progression | Genetic aspects | Research | Homocysteine | Amino acid metabolism | Transcription factors | Adenosylmethionine | High cholesterol diet | Bcl-2 protein | Laboratories | Liver | Glycine | Caspase-3 | Proteins | Elevation | Arginine | Betaine | Rodents | DNA methylation | Deoxyribonucleic acid--DNA | Glutathione | Phosphatidylethanolamine | Liver diseases | Nutrition | 5-Methyltetrahydrofolate-homocysteine S-methyltransferase | Methionine | Glycine N-methyltransferase | c-Jun protein | Caspase | Betaine-homocysteine S-methyltransferase | Gene expression | Metabolism | Fatty acids | Lymphoma | Fatty-acid synthase | Cholesterol | Molecular chains | Substrates | Depletion | Lymphocytes B | Diet | Nitric oxide | Fibrosis | DNA methyltransferase | Methylation | Nuclear reactions | Polymethyl methacrylate | B-cell lymphoma | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4640 - 4649
Dendritic cells (DC) are professional APCs that regulate innate and adaptive immunity. The role of fatty-acid synthesis in DC development and function is... 
CANCER-CELLS | APOPTOSIS | KAPPA-B ACTIVATION | UNFOLDED PROTEIN RESPONSE | CYTOKINE PRODUCTION | SYNTHASE INHIBITION | ER STRESS | MAP KINASE | MACROPHAGES | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | Fatty Acids - immunology | Leukocytes, Mononuclear - metabolism | Chemokine CCL2 - immunology | Dendritic Cells - immunology | Humans | Caspase 3 - metabolism | Male | Cyclin B1 - metabolism | Interferon-gamma - metabolism | PPAR gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Mitogen-Activated Protein Kinase Kinases - metabolism | Liver - immunology | CD8-Positive T-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Interleukin-12 - metabolism | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Intercellular Adhesion Molecule-1 - metabolism | Proto-Oncogene Proteins c-akt - immunology | T-Lymphocytes, Cytotoxic - metabolism | Endoplasmic Reticulum - immunology | Interleukin-12 - immunology | Mice | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | bcl-X Protein - metabolism | Fatty Acids - biosynthesis | Mitogen-Activated Protein Kinase Kinases - immunology | Caspase 3 - immunology | Endoplasmic Reticulum - metabolism | Genes, MHC Class II - immunology | PPAR gamma - immunology | Cyclin B1 - immunology | Leukocytes, Mononuclear - immunology | bcl-X Protein - immunology | Killer Cells, Natural - immunology | Chemokine CCL2 - metabolism | B7-2 Antigen - immunology | Fatty Acids - metabolism | Dendritic Cells - metabolism | T-Lymphocytes, Cytotoxic - immunology | B7-1 Antigen - immunology | Intercellular Adhesion Molecule-1 - immunology | Mice, Inbred C57BL | B7-1 Antigen - metabolism | Animals | Apoptosis - immunology | Interferon-gamma - immunology | Dendritic Cells - cytology | Index Medicus | Abridged Index Medicus | Fatty-acid synthesis | ER stress | NK cells | T cells | Bone marrow dendritic cells
Journal Article