X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (43450) 43450
Book Review (5020) 5020
Publication (4954) 4954
Newspaper Article (919) 919
Magazine Article (427) 427
Book Chapter (404) 404
Report (191) 191
Conference Proceeding (179) 179
Trade Publication Article (123) 123
Dissertation (97) 97
Web Resource (89) 89
Book / eBook (84) 84
Reference (70) 70
Paper (36) 36
Newsletter (16) 16
Government Document (14) 14
Data Set (10) 10
Journal / eJournal (7) 7
Market Research (2) 2
Presentation (2) 2
Video Recording (2) 2
Archival Material (1) 1
Art (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (38777) 38777
humans (26126) 26126
animals (16798) 16798
atp-binding cassette transporters - genetics (9897) 9897
p-glycoprotein (9465) 9465
male (9252) 9252
atp-binding cassette transporters - metabolism (8991) 8991
female (8844) 8844
biochemistry & molecular biology (7782) 7782
pharmacology & pharmacy (7417) 7417
mice (7368) 7368
atp-binding cassette, sub-family b, member 1 - metabolism (6370) 6370
expression (5950) 5950
multidrug-resistance (4829) 4829
oncology (4667) 4667
atp-binding cassette, sub-family b, member 1 - genetics (4411) 4411
adult (4010) 4010
drug resistance (3994) 3994
molecular sequence data (3989) 3989
middle aged (3829) 3829
proteins (3804) 3804
rats (3801) 3801
multidrug resistance (3642) 3642
cell line, tumor (3576) 3576
microbiology (3467) 3467
research (3446) 3446
gene expression (3388) 3388
cancer (3348) 3348
mutation (3274) 3274
analysis (3262) 3262
cell biology (3105) 3105
cell line (3084) 3084
gene (3048) 3048
biological transport (2976) 2976
amino acid sequence (2813) 2813
drug resistance, multiple (2766) 2766
genetic aspects (2754) 2754
cells (2700) 2700
aged (2688) 2688
drug resistance, neoplasm (2654) 2654
genes (2625) 2625
atp-binding cassette transporters (2525) 2525
base sequence (2487) 2487
antineoplastic agents - pharmacology (2396) 2396
tumor cells, cultured (2390) 2390
physiological aspects (2323) 2323
cassettes (2320) 2320
drug-resistance (2275) 2275
in-vitro (2213) 2213
atp binding cassette transporter, sub-family g, member 2 (2165) 2165
chemotherapy (2098) 2098
escherichia-coli (2066) 2066
transporter (2063) 2063
atp-binding cassette, sub-family b, member 1 - antagonists & inhibitors (2054) 2054
article (2052) 2052
cells, cultured (2004) 2004
genotype (2003) 2003
abc transporter (1988) 1988
protein (1936) 1936
dose-response relationship, drug (1916) 1916
phenotype (1890) 1890
pharmacokinetics (1875) 1875
identification (1869) 1869
rna, messenger - metabolism (1864) 1864
atp-binding cassette transporters - chemistry (1839) 1839
abc transporters (1831) 1831
protein binding (1817) 1817
atp-binding cassette transporters - physiology (1757) 1757
genetics & heredity (1746) 1746
transport (1735) 1735
transfection (1730) 1730
cholesterol (1687) 1687
drug resistance in microorganisms (1687) 1687
neoplasm proteins - metabolism (1679) 1679
mice, knockout (1677) 1677
polymerase chain reaction (1674) 1674
abridged index medicus (1671) 1671
cholesterol - metabolism (1646) 1646
doxorubicin - pharmacology (1629) 1629
atp binding cassette transporter, sub-family b (1626) 1626
metabolism (1617) 1617
biophysics (1593) 1593
immunology (1588) 1588
apoptosis (1584) 1584
bacterial proteins - genetics (1582) 1582
kinetics (1565) 1565
reverse transcriptase polymerase chain reaction (1562) 1562
atp binding cassette transporter 1 (1560) 1560
atp binding cassette transporter, sub-family b - genetics (1553) 1553
neoplasm proteins - genetics (1545) 1545
gene-expression (1544) 1544
resistance (1543) 1543
research article (1533) 1533
multidisciplinary sciences (1528) 1528
liver - metabolism (1489) 1489
blotting, western (1479) 1479
rna, messenger - genetics (1478) 1478
immunohistochemistry (1475) 1475
hematology (1474) 1474
binding sites (1468) 1468
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (17) 17
UTL at Downsview - May be requested (17) 17
Online Resources - Online (9) 9
Gerstein Science - Stacks (7) 7
Law (Bora Laskin) - Stacks (7) 7
Music - Stacks (6) 6
Engineering & Comp. Sci. - Stacks (5) 5
UofT at Scarborough - Stacks (5) 5
Collection Dvlpm't (Acquisitions) - Vendor file (4) 4
Faculty of Information - Stacks (4) 4
St. Michael's College (John M. Kelly) - 2nd Floor (4) 4
UofT at Mississauga - Stacks (4) 4
Collection Dvlpm't (Acquisitions) - Closed Orders (3) 3
Music - Library use only (3) 3
OISE - Stacks (3) 3
Pontifical Inst. Mediaeval Studies - Library use only (2) 2
Victoria University E.J. Pratt - Stacks (2) 2
Chemistry (A D Allen) - Stacks (1) 1
Engineering & Comp. Sci. - Special Collections (1) 1
Faculty of Information - May be requested in 6-10 wks (1) 1
Law (Bora Laskin) - Closed Orders (1) 1
Media Commons - Storage (1) 1
Music - Reference (1) 1
OISE - Children's Literature (1) 1
OISE - On order (1) 1
Robarts - Course Reserves (1) 1
Royal Ontario Museum - Far Eastern (1) 1
Royal Ontario Museum - Stacks (1) 1
Scarborough Hospital - Online (1) 1
St. Michael's College (John M. Kelly) - 3rd Floor (1) 1
St. Michael's College (John M. Kelly) - Audio Visual (1) 1
St. Michael's Hospital - Online (1) 1
Thomas Fisher Rare Book - Reference (1) 1
UofT at Mississauga - 1st Floor (1) 1
Victoria University CRRS - Library use only (1) 1
Victoria University E.J. Pratt - Internal dept (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (44172) 44172
Chinese (788) 788
Japanese (331) 331
French (103) 103
Russian (92) 92
Spanish (84) 84
German (66) 66
Polish (40) 40
Korean (26) 26
Czech (17) 17
Hungarian (17) 17
Dutch (11) 11
Portuguese (11) 11
Turkish (11) 11
Italian (8) 8
Finnish (6) 6
Ukrainian (6) 6
Danish (4) 4
Persian (4) 4
Hebrew (3) 3
Norwegian (3) 3
Slovak (3) 3
Romanian (2) 2
Swedish (2) 2
Amharic (1) 1
Arabic (1) 1
Indonesian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 7, pp. 1133 - 1142
RATIONALE:High-density lipoprotein (HDL) is a heterogeneous population of particles. Differences in the capacities of HDL subfractions to remove cellular... 
foam cells | HDL | ATP-binding cassette transporters | macrophages | cholesterol, HDL | ATP binding cassette transporter 1 | Cholesterol | cholesterol-efflux regulatory protein | ABCA1 | CARDIAC & CARDIOVASCULAR SYSTEMS | APOA-I | HIGH-DENSITY-LIPOPROTEIN | TANGIER DISEASE | EFFLUX | MESSENGER-RNA | CASSETTE TRANSPORTER A1 | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ABCG1 | APOLIPOPROTEIN-A-I | Lipoproteins - deficiency | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cricetulus | Humans | Lipoproteins, HDL - metabolism | ATP-Binding Cassette Transporters - physiology | Recombinant Fusion Proteins - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP Binding Cassette Transporter 1 - physiology | Biological Transport | Foam Cells - metabolism | Lipoproteins, HDL2 - metabolism | CHO Cells | Cell Line | Cricetinae | Tangier Disease - enzymology | Tangier Disease - genetics | Cholesterol, HDL - metabolism | Mice, Inbred C57BL | Gene Silencing | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Lipoproteins - physiology | Mice, Knockout | Particle Size | Macrophages - metabolism | Animals | ATP Binding Cassette Transporter 1 - deficiency | ATP Binding Cassette Transporter 1 - antagonists & inhibitors | Mice | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
Journal Article
Toxicological Sciences, ISSN 1096-6080, 11/2013, Volume 136, Issue 1, pp. 216 - 241
The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it serves as the primary route of elimination for monovalent bile... 
Multidrug resistance- associated protein | Drug-induced liver injury | ATP-binding cassette transporter | Transporter | Bile acid | Bile salt export pump | drug-induced liver injury | BSEP | MRP2 | bile acid | SALT EXPORT PUMP | multidrug resistance- associated protein | CHOLESTASIS | INDUCED LIVER-INJURY | IN-VITRO | INHIBITION | transporter | DRUG DEVELOPMENT | bile salt export pump | TOXICOLOGY | HEPATOTOXICITY | BILE-ACIDS | Humans | Drug-Related Side Effects and Adverse Reactions - metabolism | Male | ATP-Binding Cassette Transporters - genetics | Biological Transport | Liver - drug effects | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - genetics | Toxicity Tests - methods | ATP Binding Cassette Transporter, Sub-Family B - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - etiology | Recombinant Proteins - metabolism | Risk Assessment | Liver - metabolism | Risk Factors | Rats | Drug-Related Side Effects and Adverse Reactions - etiology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Rats, Sprague-Dawley | Animals | ATP Binding Cassette Subfamily B Member 11 | Chemical and Drug Induced Liver Injury - metabolism | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Pharmacokinetics | ATP Binding Cassette Transporter, Sub-Family B - genetics | Multidrug Resistance-Associated Proteins - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Cluster Analysis | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 2014, Volume 134, Issue 6, pp. 1484 - 1494
Crizotinib is an oral tyrosine kinase inhibitor approved for treating patients with non-small cell lung cancer (NSCLC) containing an anaplastic lymphoma kinase... 
brain accumulation | crizotinib | P‐glycoprotein | ALK inhibitor | elacridar | P-glycoprotein | EML4-ALK FUSION GENE | METASTASES | MOUSE | PENETRATION | GF120918 | BIOAVAILABILITY | CELL LUNG-CANCER | ANAPLASTIC LYMPHOMA KINASE | ONCOLOGY | MULTIDRUG-RESISTANCE | PHASE-I | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Pyridines - pharmacokinetics | Biological Availability | Male | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | ATP-Binding Cassette Transporters - physiology | Brain - metabolism | Tissue Distribution | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Drug Therapy, Combination | Neoplasm Proteins - genetics | Pyrazoles - pharmacokinetics | Pyrazoles - pharmacology | Protein Kinase Inhibitors - pharmacokinetics | Tetrahydroisoquinolines - pharmacology | Administration, Oral | Cells, Cultured | Mice, Knockout | Brain - drug effects | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Acridines - pharmacology | ATP Binding Cassette Transporter, Sub-Family B | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Plasma | Chemotherapy | Brain cancer | Rodents | Lymphomas | Glycoproteins | Metastasis | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 10/2008, Volume 68, Issue 19, pp. 7905 - 7914
Lapatinib is active at the ATP-binding site of Lyrosine kinases that are associated with the human epidermal growth factor receptor (Her-1 or ErbB1) and Her-2.... 
BREAST-CANCER | ACQUIRED MUTATIONS | IN-VITRO | HUMAN P-GLYCOPROTEIN | ONCOLOGY | METHOTREXATE TRANSPORT | TYROSINE KINASE INHIBITOR | DRUG-RESISTANCE | PHASE-I | CATALYTIC CYCLE | ABCG2 | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Neoplasms - metabolism | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Adenosine Triphosphatases - drug effects | Quinazolines - pharmacokinetics | Neoplasm Proteins - antagonists & inhibitors | Paclitaxel - pharmacokinetics | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | Dose-Response Relationship, Drug | Transfection | ATP-Binding Cassette Transporters - genetics | Neoplasms - genetics | Up-Regulation - physiology | ATP-Binding Cassette Transporters - metabolism | Quinazolines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Paclitaxel - administration & dosage | Drug Resistance, Multiple - genetics | Cells, Cultured | Adenosine Triphosphatases - metabolism | Neoplasms - drug therapy | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Tumor Burden - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | ATP Binding Cassette Transporter, Sub-Family B | Mice | Neoplasms - pathology | Quinazolines - pharmacology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | Index Medicus | BCRP | multidrug resistance | ABCB1 | P-gp | MXR | lapatinib | EGFR tyrosine kinase inhibitor
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 01/2014, Volume 1838, Issue 1, pp. 134 - 147
ATP Binding Cassette (ABC) transporters play prominent roles in numerous cellular processes and many have been implicated in human diseases. Unfortunately,... 
P-glycoprotein | Membrane protein structure | ATP Binding Cassette transporter | Lipid–protein interaction | Membrane transport | ABCA4 | Lipid-protein interaction | ATPASE ACTIVITY | DRUG-BINDING | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | 10-glycoprotein | ELECTRON-MICROSCOPY | BINDING CASSETTE TRANSPORTER | BIOPHYSICS | Lipid protein interaction | PURIFICATION | MULTIDRUG-RESISTANCE | EXPRESSION | RECONSTITUTION | P-GLYCOPROTEIN REVEALS | Temperature | Baculoviridae - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Baculoviridae - genetics | Colorimetry | Membrane Lipids - chemistry | Recombinant Proteins - isolation & purification | ATP-Binding Cassette Transporters - chemistry | Sf9 Cells - virology | ATP-Binding Cassette Transporters - genetics | Protein Structure, Quaternary | ATP-Binding Cassette Transporters - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Protein Stability | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Microscopy, Electron | ATP-Binding Cassette Transporters - isolation & purification | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | ATP Binding Cassette Transporter, Sub-Family B | ATP-Binding Cassette, Sub-Family B, Member 1 - isolation & purification | Membrane lipids | Precipitation (Meteorology) | Membrane proteins
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2013, Volume 33, Issue 7, pp. 1484 - 1493
OBJECTIVE—Transintestinal cholesterol excretion (TICE) is an alternate pathway to hepatobiliary secretion. Our study aimed at identifying molecular mechanisms... 
PCSK9 | ATP-binding cassette transporter B1 | Lipoprotein | Low-density lipoprotein receptor | Transintestinal cholesterol excretion | MULTIDRUG TRANSPORTER | low-density lipoprotein receptor | lipoprotein | LDL RECEPTOR | KNOCKOUT MICE | COMPLETE BILE DIVERSION | P-GLYCOPROTEIN | BILIARY STEROL SECRETION | PLASMA-CHOLESTEROL | IN-VIVO | CONVERTASE SUBTILISIN/KEXIN TYPE-9 | PERIPHERAL VASCULAR DISEASE | transintestinal cholesterol excretion | HEMATOLOGY | DENSITY-LIPOPROTEIN RECEPTOR | Lovastatin - pharmacology | Humans | Male | Proprotein Convertases - genetics | Jejunum - drug effects | Time Factors | Serine Endopeptidases - genetics | ATP Binding Cassette Transporter, Subfamily B - genetics | Recombinant Proteins - metabolism | Receptors, LDL - genetics | Jejunum - enzymology | Serine Endopeptidases - deficiency | Cholesterol, HDL - metabolism | Mice, Inbred C57BL | Proprotein Convertases - metabolism | ATP Binding Cassette Transporter, Subfamily B - deficiency | Receptors, LDL - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 - deficiency | Cholesterol - metabolism | Proprotein Convertases - deficiency | ATP Binding Cassette Transporter, Subfamily B - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | Mice, Knockout | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Biopsy | Cholesterol, LDL - metabolism | Mice | Serine Endopeptidases - metabolism | Proprotein Convertase 9 | Index Medicus
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 07/2010, Volume 334, Issue 1, pp. 147 - 155
Journal Article
2000, Highsmith Press handbook series, ISBN 157950034X, 85
Book
Drug Metabolism and Disposition, ISSN 0090-9556, 2013, Volume 41, Issue 4, pp. 754 - 762
Journal Article
Biochemical journal, ISSN 0264-6021, 2003, Volume 369, Issue Part 3, pp. 539 - 547
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that controls expression of genes involved in lipid metabolism and is... 
ATP binding cassette (ABC) transporter | Phospholipid | Peroxisome proliferator-activated receptor α (PPARα)-null mouse | Bile salt | Bile | BILE-SALTS | BILIARY LIPID SECRETION | SALT EXPORT PUMP | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | P-GLYCOPROTEIN EXPRESSION | DEFICIENT MICE | HEPATIC TRANSPORT | peroxisome proliferator-activated receptor alpha (PPAR alpha)-null mouse | bile | LIPOPROTEIN METABOLISM | bile salt | GENE-EXPRESSION | CHOLESTEROL 7-ALPHA-HYDROXYLASE | phospholipid | Organic Anion Transporters, Sodium-Independent - genetics | Liver - pathology | Lipoproteins - genetics | Bile - chemistry | Bile - metabolism | Male | Transcription Factors - drug effects | Clofibric Acid - pharmacology | Taurochenodeoxycholic Acid - pharmacology | ATP-Binding Cassette Transporters - genetics | Clofibric Acid - analogs & derivatives | Liver - drug effects | Mice, Mutant Strains | Organic Anion Transporters, Sodium-Independent - metabolism | Symporters | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Fibric Acids | ATP Binding Cassette Transporter 1 | Hepatocytes - physiology | Lipids - secretion | Receptors, Cytoplasmic and Nuclear - drug effects | Liver - metabolism | Cells, Cultured | Peroxisome Proliferators - pharmacology | Receptors, Cytoplasmic and Nuclear - genetics | Pyrimidines - pharmacology | Transcription Factors - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Organ Size - drug effects | Animals | Carrier Proteins - metabolism | ATP Binding Cassette Subfamily B Member 11 | ATP-Binding Cassette Transporters - drug effects | Membrane Transport Proteins | ATP Binding Cassette Transporter, Sub-Family B - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 8 | Mice | ATP Binding Cassette Transporter, Sub-Family B - genetics | Taurochenodeoxycholic Acid - administration & dosage | Organic Anion Transporters, Sodium-Dependent | ATP Binding Cassette Transporter, Sub-Family B - drug effects | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
The Plant Cell, ISSN 1040-4651, 1/2007, Volume 19, Issue 1, pp. 131 - 147
Directional transport of the phytohormone auxin is established primarily at the point of cellular efflux and is required for the establishment and maintenance... 
Proteins | Yeasts | Hypocotyls | Plant roots | HeLa cells | Auxins | Cell membranes | Plants | Seedlings | Plant cells | ABC TRANSPORTER | ROOT GRAVITROPISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT DEVELOPMENT | POLAR TRANSPORT | DRUG-RESISTANCE | PLASMA-MEMBRANE | PLANT SCIENCES | CELL BIOLOGY | GENE-EXPRESSION | TWISTED DWARF1 | EFFLUX CARRIER | RNA-POLYMERASE | Hypocotyl - genetics | ATP Binding Cassette Transporter, Sub-Family B - analysis | Plant Roots - genetics | RNA, Messenger - metabolism | ATP-Binding Cassette Transporters - physiology | Arabidopsis Proteins - metabolism | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Hypocotyl - metabolism | Arabidopsis Proteins - analysis | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | Plant Roots - metabolism | Indoleacetic Acids - metabolism | Membrane Transport Proteins - analysis | ATP-Binding Cassette Transporters - analysis | Arabidopsis - metabolism | Arabidopsis - genetics | Two-Hybrid System Techniques | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Biological Transport - physiology | Mutation | ATP Binding Cassette Transporter, Sub-Family B - genetics | Plant translocation | Physiological aspects | Glycoproteins | Research | Arabidopsis | Index Medicus
Journal Article