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PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, pp. e0146129 - e0146129
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, pp. e0162082 - e0162082
Background Diabetes mellitus type 2 (T2DM) is associated with oxidative stress which in turn can lead to DNA damage. The aim of the present study was to... 
KIDNEY-DISEASE | GLYCEMIC CONTROL | PLASMA | COMET ASSAY | GLUTATHIONE | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | BETA-CELL FAILURE | COMPLICATIONS | ASSOCIATION | CANCER | Blood Pressure | Superoxide Dismutase - genetics | Catalase - blood | F2-Isoprostanes - blood | Oxidative Stress | DNA Ligases - genetics | Diabetes Mellitus, Type 2 - genetics | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Superoxide Dismutase - blood | Poly-ADP-Ribose Binding Proteins | DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics | Malondialdehyde - blood | Aged, 80 and over | Adult | Cholesterol, LDL - blood | Female | Body Mass Index | Hypoglycemic Agents - therapeutic use | Cross-Sectional Studies | Catalase - genetics | Glutathione Peroxidase - blood | Gene Expression Regulation | DNA-(Apurinic or Apyrimidinic Site) Lyase - blood | Xenopus Proteins | DNA-Binding Proteins - genetics | Glutathione Peroxidase - genetics | DNA Ligases - blood | Diabetes Mellitus, Type 2 - diagnosis | Leukocytes, Mononuclear - chemistry | DNA Repair | Triglycerides - blood | Cholesterol, HDL - blood | DNA Ligase ATP | Aged | DNA Damage | DNA-Binding Proteins - blood | Diabetes Mellitus, Type 2 - pathology | Diabetes Mellitus, Type 2 - drug therapy | X-ray Repair Cross Complementing Protein 1 | Lipoproteins, LDL - blood | Glutathione - blood | Type 2 diabetes | Oxidative stress | Complications and side effects | Care and treatment | DNA damage | Analysis | Research | Health aspects | DNA repair | Lipoproteins (low density) | Thiols | Medical services | Leukocytes (mononuclear) | Superoxide dismutase | Biochemistry | Base excision repair | Blood | Antioxidants | Hyperglycemia | Catalase | Atherosclerosis | Hemoglobin | Peripheral blood mononuclear cells | Peroxidase | Blood pressure | Repair | Damage | Lipoproteins (high density) | Diabetes mellitus (non-insulin dependent) | Deoxyribonucleic acid--DNA | Glutathione | Glutathione peroxidase | Stresses | Gel electrophoresis | Medical treatment | Diabetes mellitus | Superoxide | Triglycerides | Gene expression | Patients | Insulin | Malondialdehyde | Cholesterol | Stress | Body mass | Kidney diseases | Diabetes | Health risk assessment | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0179654 - e0179654
Background This study aimed to investigate the pathophysiology of hepatic microcirculatory dysfunction in non-alcoholic fatty liver disease (NAFLD). Methods In... 
PATHOGENESIS | METABOLIC SYNDROME | ENDOTHELIAL DYSFUNCTION | MULTIDISCIPLINARY SCIENCES | ELEVATED LEVELS | CARDIOVASCULAR-DISEASE | MICROCIRCULATION | STEATOHEPATITIS | MODEL | INFLAMMATORY RESPONSE | PROGRESSION | Non-alcoholic Fatty Liver Disease - pathology | Oxidative Stress | Rats, Wistar | Cholesterol - blood | Tumor Necrosis Factor-alpha - blood | Male | Interleukin-1beta - blood | Microcirculation - physiology | Diet, High-Fat | Liver - diagnostic imaging | Blood Pressure - physiology | Receptor for Advanced Glycation End Products - genetics | Real-Time Polymerase Chain Reaction | Leukocytes - cytology | Blood Glucose - analysis | Glycation End Products, Advanced - analysis | Catalase - genetics | Liver - metabolism | Receptor for Advanced Glycation End Products - metabolism | Rats | Non-alcoholic Fatty Liver Disease - metabolism | Catalase - metabolism | Liver - blood supply | Animals | Triglycerides - blood | Catalase - analysis | Leukocytes - metabolism | Physiology, Pathological | Microcirculation disorders | Fatty liver | Research | Pathogenesis | Liver | Impairment | Leukocytes | Glucose | Blood | Enzymatic activity | Lasers | Imaging | Blood pressure | Stresses | Advanced glycosylation end products | Liver diseases | Glycosylation | Metabolism | Gene expression | Insulin | Studies | Polymerase chain reaction | Pathology | Diet | Perfusion | Disturbances | Liver cirrhosis | Endocrinology | Oxidative stress | Enzyme activity | Laboratories | Fluorescence | High fat diet | Catalase | Rodents | Ultrasound | Injuries | Age | Enzyme-linked immunosorbent assay | Hypertension | Fasting | Triglycerides | Inflammation | Histology | Adhesion | Cholesterol | Blood flow | Steatosis | Feeding | Hypotheses | Microscopy | Insulin resistance | Microvasculature | Diabetes | Leukocyte rolling | Index Medicus
Journal Article
Journal Article
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 2013, Volume 36, Issue 2, pp. 472 - 483
Highlights • Diabetic tissues dysfunction results from hyperglycemia and oxidative stress. • Excessive production of ROS decreases the insulin secretion. • To... 
Emergency | Lipid profile | Oxidative stress | Rebaudioside A | Diabetes | Streptozotocin | VITAMIN-C | GLUTATHIONE-PEROXIDASE | DNA-DAMAGE | MELLITUS | INSULIN | STEVIOSIDE | ENVIRONMENTAL SCIENCES | PHARMACOLOGY & PHARMACY | COMPLICATIONS | TOXICOLOGY | SUPEROXIDE-DISMUTASE | HYPERTENSIVE-RATS | Diabetes Mellitus, Experimental - drug therapy | Liver - pathology | Catalase - blood | Rats, Wistar | Cholesterol - blood | Diabetes Mellitus, Experimental - genetics | Superoxide Dismutase - blood | Male | Insulin - blood | Diabetes Mellitus, Experimental - blood | Kidney - metabolism | Hypoglycemic Agents - administration & dosage | Liver - drug effects | Lipid Peroxides - blood | Lipids - blood | Lipid Peroxidation - drug effects | Fatty Acids, Nonesterified - blood | Phospholipids - blood | Ascorbic Acid - blood | Diterpenes, Kaurane - pharmacology | Kidney - drug effects | Administration, Oral | Glutathione Peroxidase - blood | Liver - metabolism | Rats | Vitamin E - blood | Thiobarbituric Acid Reactive Substances - metabolism | Antioxidants - pharmacology | Biomarkers - blood | Hypolipidemic Agents - pharmacology | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Animals | Antioxidants - administration & dosage | Hypolipidemic Agents - administration & dosage | Triglycerides - blood | Diabetes Mellitus, Experimental - pathology | DNA Damage | Oxidative Stress - drug effects | Blood Glucose - metabolism | Diterpenes, Kaurane - administration & dosage | Glutathione - blood | Antioxidants | Lipids | Hyperglycemia | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article