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International Journal of Pediatric Otorhinolaryngology, ISSN 0165-5876, 2016, Volume 92, pp. 61 - 66
Abstract Objective Cisplatin is commonly used to treat solid tumors. However, permanent hearing loss is a major side effect of cisplatin chemotherapy and often... 
Otolaryngology | Pediatrics | Peanut sprout | Cell death | Cisplatin | Ototoxicity | Apoptosis | RESVERATROL | CELLS | ACTIVATION | PROTECTION | MECHANISMS | TOXICITY | ANTIOXIDANT | OTORHINOLARYNGOLOGY | PEDIATRICS | STRESS | EXPRESSION | Up-Regulation | Catalase - drug effects | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Plant Extracts - pharmacology | Heme Oxygenase-1 - drug effects | NAD(P)H Dehydrogenase (Quinone) - genetics | Antineoplastic Agents - toxicity | Heme Oxygenase-1 - genetics | Poly(ADP-ribose) Polymerases - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Cisplatin - toxicity | Oxidation-Reduction - drug effects | Caspases - drug effects | Glutathione Peroxidase - drug effects | Real-Time Polymerase Chain Reaction | Cell Line | Cell Survival - drug effects | Catalase - genetics | Membrane Proteins - genetics | NF-E2-Related Factor 2 - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Blotting, Western | Glutamate-Cysteine Ligase - drug effects | Glutathione Peroxidase - genetics | Seedlings | Hair Cells, Auditory - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Animals | NAD(P)H Dehydrogenase (Quinone) - drug effects | NF-E2-Related Factor 2 - metabolism | Proto-Oncogene Proteins c-bcl-2 - drug effects | Membrane Proteins - drug effects | Glutamate-Cysteine Ligase - genetics | Mice | In Vitro Techniques | Arachis | Labyrinth Supporting Cells - drug effects | Antioxidants | Medical colleges | Chemotherapy | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e104020
Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology. TLR4 may have a role in... 
OXIDATIVE STRESS | ACTIVATION | IMMUNE-SYSTEM | ENDOTHELIAL DYSFUNCTION | RESISTANCE ARTERIES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | LIPOPOLYSACCHARIDE | SMOOTH-MUSCLE-CELLS | EXPRESSION | BLOOD-PRESSURE | Reactive Oxygen Species - metabolism | Rats, Wistar | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Heart Rate - drug effects | Phenylephrine - pharmacology | Superoxides - metabolism | Blood Pressure - drug effects | Aorta - physiopathology | Hypertension - genetics | Toll-Like Receptor 4 - antagonists & inhibitors | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Rats, Inbred SHR | Angiotensin II - pharmacology | Acetylcholine - pharmacology | Aorta - drug effects | Endothelium, Vascular - physiopathology | Toll-Like Receptor 4 - genetics | Antioxidants - pharmacology | Toll-Like Receptor 4 - metabolism | Vasoconstriction - drug effects | Hypertension - pathology | Hypertension - physiopathology | Aorta - pathology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Endothelium, Vascular - pathology | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Vasodilation - drug effects | In Vitro Techniques | Potentiation | Oxidative stress | Reactive oxygen species | Biomedical research | Immunoglobulin G | Medical services | Smooth muscle | Innate immunity | mRNA | Activation | Biochemistry | Immunity | Experiments | Contraction | NAD(P)H oxidase | Ethics | Renin | Catalase | Rodents | Atherosclerosis | Phenylephrine | Toll-like receptors | Aorta | Physiology | Blood pressure | Angiotensin II | Heart diseases | Hypertension | Heparan sulfate | Muscles | Rats | Superoxide | Inflammation | Adaptive immunity | TLR4 protein | Endothelium | Heart rate | NAD | Pathology | Angiotensin | Acetylcholine | Cardiovascular diseases
Journal Article
Journal of Experimental Botany, ISSN 0022-0957, 11/2001, Volume 52, Issue 364, pp. 2115 - 2126
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 10/2006, Volume 33, Issue 10, pp. 940 - 945
SUMMARY • Chronic hyperglycaemia in diabetes leads to the overproduction of free radicals and evidence is increasing that these contribute to the development... 
lipid peroxidation | diabetic nephropathy | oxidative stress | curcumin | Lipid peroxidation | Oxidative stress | Diabetic nephropathy | Curcumin | PATHOGENESIS | PHYSIOLOGY | PHARMACOLOGY & PHARMACY | Diabetes Mellitus, Experimental - drug therapy | Glutathione - metabolism | Plant Extracts - pharmacology | Body Weight - drug effects | Diabetic Nephropathies - drug therapy | Diabetic Nephropathies - blood | Diabetes Mellitus, Experimental - mortality | Diabetes Mellitus, Experimental - blood | Blood Pressure - drug effects | Drug Evaluation, Preclinical | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Kidney - drug effects | Curcumin - pharmacology | Rats | Survival Rate | Kidney - anatomy & histology | Kidney - cytology | Rats, Sprague-Dawley | Diabetic Nephropathies - mortality | Blood Glucose - drug effects | Catalase - metabolism | Animals | Curcuma | Oxidative Stress - drug effects | Kidney, drug effects | Kidney, anatomy and histology | Oxidative Stress, drug effects | Superoxide Dismutase, metabolism | Blood Glucose, drug effects | Diabetes Mellitus, Experimental, mortality | Curcumin, pharmacology | Diabetic Nephropathies, blood | Glutathione, metabolism | Blood Pressure, drug effects | Plant Extracts, pharmacology | Catalase, metabolism | Diabetes Mellitus, Experimental, drug therapy | Diabetes Mellitus, Experimental, blood | Diabetic Nephropathies, drug therapy | Malondialdehyde, metabolism | Diabetic Nephropathies, mortality | Body Weight, drug effects | Kidney, cytology | Diabetic nephropathies
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52439
Aquaporin (AQP) proteins have been shown to transport water and other small molecules through biological membranes, which is crucial for plants to combat... 
ARABIDOPSIS-THALIANA | EXPRESSION ANALYSIS | MEMBRANE INTRINSIC PROTEINS | HYDRAULIC CONDUCTIVITY | MULTIDISCIPLINARY SCIENCES | ANTIOXIDANT ENZYMES | FUNCTIONAL-ANALYSIS | HYDROGEN-PEROXIDE | WATER TRANSPORT | SIGNALING MOLECULE | ABSCISIC-ACID | Triticum - physiology | Adaptation, Physiological - drug effects | Seedlings - genetics | Gene Expression Profiling | Dehydration | Aquaporins - genetics | Adaptation, Physiological - genetics | Droughts | Plants, Genetically Modified | Oocytes - drug effects | Cell Membrane - metabolism | Plant Proteins - metabolism | Stress, Physiological - drug effects | Cell Membrane - drug effects | Superoxide Dismutase - metabolism | Polyethylene Glycols - pharmacology | Tobacco - physiology | Malondialdehyde - metabolism | Permeability - drug effects | Oocytes - metabolism | Stress, Physiological - genetics | Xenopus laevis | Hydrogen Peroxide - pharmacology | Water - metabolism | Aquaporins - metabolism | Up-Regulation - genetics | Seedlings - drug effects | Catalase - metabolism | Triticum - genetics | Up-Regulation - drug effects | Abscisic Acid - pharmacology | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Animals | Tobacco - genetics | Osmotic Pressure - drug effects | Tobacco - enzymology | Triticum - drug effects | Antioxidants | Proteins | Care and treatment | Genes | Abscisic acid | Substance abuse | Genetic engineering | Superoxide | Dehydration (Physiology) | Wheat | Phosphorylation | Membranes | Hydrogen peroxide | Transcription | Laboratories | Superoxide dismutase | Genomes | Biosynthesis | Phosphatidylinositol 4,5-diphosphate | Transgenic plants | Oocytes | Genotype & phenotype | International cooperation | Catalase | Moisture content | Education | Polyethylene glycol | Drought resistance | Water content | Biological membranes | Life sciences | Trends | Fusion protein | Damage accumulation | Localization | Drought | Stresses | Plants (botany) | Polyethylene | Channel gating | Abiotic stress | Aquaporins | Biophysics | Gene expression | Malondialdehyde | Stress | Salinity | Signaling | Tobacco
Journal Article
Free Radical Research, ISSN 1071-5762, 05/2010, Volume 45, Issue 5, pp. 507 - 517
Abstract The bioactive flavonoid baicalein has been shown to have radioprotective activity, although the molecular mechanism is poorly understood in vivo.... 
Baicalein | NF-κB | FOXOs | inflammation | ionizing radiation | GAMMA | FORKHEAD TRANSCRIPTION FACTOR | TISSUE-INJURY | CELLS | OXIDATIVE STRESS | ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-NECROSIS-FACTOR | NF-kappa B | MANGANESE SUPEROXIDE-DISMUTASE | RESISTANCE | Lipid Peroxidation - radiation effects | Extracellular Signal-Regulated MAP Kinases - radiation effects | NF-kappa B - metabolism | Nephritis - prevention & control | NF-kappa B - radiation effects | Creatinine - metabolism | Inflammation - metabolism | Kidney - metabolism | Superoxide Dismutase - radiation effects | Forkhead Transcription Factors - metabolism | Lipid Peroxidation - drug effects | Oxidation-Reduction - drug effects | Radiation-Protective Agents - pharmacology | Catalase - radiation effects | Urea - metabolism | Phosphorylation - drug effects | Signal Transduction - radiation effects | Radiation Injuries, Experimental - metabolism | Kidney - drug effects | Superoxide Dismutase - drug effects | Kidney - radiation effects | Signal Transduction - drug effects | X-Rays | Forkhead Box Protein O1 | Inflammation - prevention & control | Mice | NF-kappa B - drug effects | Extracellular Signal-Regulated MAP Kinases - drug effects | Glutathione - metabolism | Oxidation-Reduction - radiation effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Forkhead Transcription Factors - drug effects | Glutathione - drug effects | Radiation Injuries, Experimental - drug therapy | Oncogene Protein v-akt - metabolism | Superoxide Dismutase - metabolism | Flavanones - pharmacology | Mice, Inbred C57BL | Oncogene Protein v-akt - drug effects | Antioxidants - pharmacology | Forkhead Transcription Factors - radiation effects | Oncogene Protein v-akt - radiation effects | Creatinine - urine | Glutathione - radiation effects | Catalase - metabolism | Urea - radiation effects | Animals | Urea - urine | Nephritis - metabolism | Creatinine - radiation effects
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2014, Volume 58, Issue 11, pp. 6627 - 6638
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0129589
Group A protein phosphatases 2Cs (PP2Cs) are essential components of abscisic acid (ABA) signaling in Arabidopsis; however, the function of group F2 subfamily... 
SIGNAL-TRANSDUCTION | ABA | RESPONSES | ARABIDOPSIS-THALIANA | OXIDATIVE DAMAGE | TOLERANCE | MULTIDISCIPLINARY SCIENCES | PLANTS | ABSCISIC-ACID | TRANSCRIPTION FACTOR | EXPRESSION | Transcription, Genetic - drug effects | Genes, Plant | Sodium Chloride - pharmacology | Phosphoprotein Phosphatases - metabolism | Molecular Sequence Data | Plant Roots - genetics | Gene Expression Profiling | Protein Transport - drug effects | Plant Roots - drug effects | Salt-Tolerance - drug effects | Germination - genetics | Plants, Genetically Modified | Cloning, Molecular | Salt-Tolerance - genetics | Plant Proteins - metabolism | Stress, Physiological - drug effects | Triticum - enzymology | Plant Roots - growth & development | Superoxide Dismutase - metabolism | Tobacco - physiology | Germination - drug effects | Malondialdehyde - metabolism | Subcellular Fractions - drug effects | Stress, Physiological - genetics | Hydrogen Peroxide - pharmacology | Oxidative Stress - genetics | Protein Phosphatase 2C | Tobacco - drug effects | Down-Regulation - drug effects | Subcellular Fractions - metabolism | Salinity | Catalase - metabolism | Triticum - genetics | Up-Regulation - drug effects | Abscisic Acid - pharmacology | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Phosphoprotein Phosphatases - genetics | Tobacco - genetics | Oxidative Stress - drug effects | Triticum - drug effects | Antioxidants | Arabidopsis thaliana | Abscisic acid | Genetic engineering | Phosphatases | Oxidative stress | Biotechnology | Reactive oxygen species | Salts | Phosphorylation | Transcription factors | Hydrogen peroxide | Transcription | Laboratories | Phosphoprotein phosphatase | Genomics | Plant resistance | Biology | Phosphatase | Transgenic plants | Proteins | Oxidation resistance | International cooperation | Genetically altered foods | Education | Life sciences | Agriculture | Fusion protein | Stress response | Localization | Sensitivity analysis | Abiotic stress | Crops | Biophysics | Sodium chloride | Gene expression | Seedlings | Signaling | Tobacco | Acids | Protein phosphatase | Wheat
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 02/2017, Volume 95, pp. 1216 - 1222
The present study evaluated the ameliorative effects of Trametes orientalis polysaccharide (TOP-2) against cyclophosphamide (CP) induced toxicity in mice.... 
Antioxidant | Trametes orientalis polysaccharide | Immunomodulatory | IMMUNITY | POLYMER SCIENCE | IMMUNOMODULATORY ACTIVITY | ANTIOXIDANT ACTIVITIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTITUMOR-ACTIVITY | IDENTIFICATION | FREE-RADICALS | PROTECTS | SUPPLEMENTATION | MYELOSUPPRESSION | IN-VITRO | CHEMISTRY, APPLIED | Spleen - immunology | Antioxidants - chemistry | Kidney - immunology | Male | Spleen - drug effects | Cyclophosphamide - adverse effects | T-Lymphocytes, Cytotoxic - drug effects | Liver - immunology | Liver - drug effects | Killer Cells, Natural - immunology | Female | Anti-Inflammatory Agents - isolation & purification | Cyclophosphamide - antagonists & inhibitors | Macrophages - immunology | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | T-Lymphocytes, Cytotoxic - immunology | Glutathione Peroxidase - metabolism | Phagocytosis - drug effects | Kidney - drug effects | Anti-Inflammatory Agents - pharmacology | Catalase - immunology | Immunosuppressive Agents - antagonists & inhibitors | Antioxidants - pharmacology | Thymus Gland - drug effects | Catalase - metabolism | Superoxide Dismutase - immunology | Immunosuppression | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - isolation & purification | Malondialdehyde - immunology | Fungal Polysaccharides - isolation & purification | Glutathione Peroxidase - immunology | Heart - drug effects | Immunosuppressive Agents - adverse effects | Macrophages - drug effects | Thymus Gland - immunology | Fungal Polysaccharides - pharmacology | Killer Cells, Natural - drug effects | Mice | Oxidative Stress - drug effects | Trametes - chemistry | Fungal Polysaccharides - chemistry | Oxidative stress | Immunoglobulins | Liver | Biological response modifiers | T cells | Antioxidants | Polysaccharides | Cyclophosphamide | Interleukins | Nitric oxide | Immunotherapy | Interferon | Food supply | Index Medicus
Journal Article
Annals of Surgical Oncology, ISSN 1068-9265, 9/2012, Volume 19, Issue 9, pp. 3097 - 3106
Journal Article
Physiologia Plantarum, ISSN 0031-9317, 06/2011, Volume 142, Issue 2, pp. 128 - 143
Journal Article