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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 48, pp. 20822 - 20827
According to the prevailing "amyloid cascade hypothesis," genetic dementias such as Alzheimer's disease and familial Danish dementia (FDD) are caused by... 
Memory disorders | Oligomers | Transgenic animals | Memory | Long term potentiation | Antibodies | Mice | Amyloids | Alzheimers disease | Dementia | ITM2b | Amyloid-β precursor protein | MECHANISM | BETA PRODUCTION | BRI2 | DEPOSITION | MULTIDISCIPLINARY SCIENCES | PATHOGENESIS | HIPPOCAMPUS | amyloid-beta precursor protein | MODELING ALZHEIMERS-DISEASE | HYPOTHESIS | PRECURSOR PROTEIN | TRANSGENIC MICE | Memory Disorders - physiopathology | Humans | Cataract - pathology | Dementia - physiopathology | Synapses - pathology | Memory Disorders - complications | Brain - metabolism | Cerebellar Ataxia - physiopathology | Neuronal Plasticity - physiology | Synapses - metabolism | Amyloid - metabolism | Long-Term Potentiation - physiology | Membrane Glycoproteins | Amyloidosis - complications | Dementia - pathology | Amyloidosis - pathology | Signal Transduction | Membrane Proteins - genetics | Brain - physiopathology | Mice, Inbred C57BL | Deafness - physiopathology | Cerebellar Ataxia - pathology | Mutation - genetics | Deafness - pathology | Cataract - complications | Animals | Cerebellar Ataxia - complications | Dementia - complications | Deafness - complications | Brain - pathology | HeLa Cells | Cataract - physiopathology | Neuroplasticity | Psychological aspects | Familial diseases | Causes of | Glycoproteins | Research | Health aspects | Proteins | Gene expression | Rodents | Animal memory | Cells | Index Medicus | Animal models | Deposits | Neurodegenerative diseases | Cognitive ability | Data processing | beta -Amyloid | Plasticity (synaptic) | Tau protein | Dementia disorders | Amyloid | Amyloidosis | Alzheimer's disease | Hippocampus | Plaques | Biological Sciences | amyloid-β precursor protein
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 4, pp. 1500 - 1505
Advances in human genetics are leading to the discovery of new disease-causing mutations at a remarkable rate. Many such mutations, however, occur in genes... 
Brain | Enzymes | Nervous system diseases | Disease models | Neurodegenerative diseases | Lipids | Mice | Lipid metabolism | Genotypes | Microglia | TOLL-LIKE-RECEPTOR-2 | neuroinflammation | MICROGLIA | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | MAST-CELLS | PHENOTYPE | CHEMOTACTIC MIGRATION | MICE | GENERATION | RECEPTORS | lipidomics | Lysophospholipids - metabolism | Microglia - metabolism | Humans | Cataract - pathology | Monoacylglycerol Lipases - deficiency | Polyneuropathies - metabolism | Monoacylglycerol Lipases - genetics | Brain - metabolism | Monoacylglycerol Lipases - metabolism | Ataxia - genetics | Ataxia - metabolism | Retinitis Pigmentosa - physiopathology | Ataxia - pathology | Disease Models, Animal | Ataxia - physiopathology | Mice, Inbred C57BL | Retinitis Pigmentosa - genetics | Retinitis Pigmentosa - metabolism | Behavior, Animal - physiology | Lipid Metabolism | Polyneuropathies - physiopathology | Cataract - metabolism | Mice, Knockout | Phenotype | Animals | Metabolic Networks and Pathways | Polyneuropathies - pathology | Brain - pathology | Polyneuropathies - genetics | Cataract - genetics | Models, Neurological | Mutation | Cataract - physiopathology | Retinitis Pigmentosa - pathology | Gene mutations | Serine | Genomics | Physiological aspects | Nervous system | Development and progression | Genetic aspects | Degeneration | Research | Health aspects | Proteins | Genotype & phenotype | Neurodegeneration | Rodents | Genetics | Neuropsychology | Index Medicus | Biological Sciences
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 10/2016, Volume 854, pp. 393 - 399
Journal Article
Cancer, ISSN 0008-543X, 08/2018, Volume 124, Issue 15, pp. 3249 - 3256
Among older adults with solid tumors, greater than one‐third report visual or hearing impairment, and 7% report both. Older patients with cancer and sensory... 
anxiety | geriatric oncology | activities of daily living | older adults | depression | hearing loss | neoplasms | cognitive dysfunction | vision disorders | GERIATRIC ASSESSMENT | VALIDATION | GLOBAL SENSORY IMPAIRMENT | CATARACT-SURGERY | CHEMOTHERAPY TOXICITY | DECLINE | ONCOLOGY | QUALITY-OF-LIFE | HEALTH | OUTCOMES | Geriatric Assessment | Depression - physiopathology | Hearing Loss - psychology | Humans | Male | Activities of Daily Living | Neoplasms - complications | Vision Disorders - physiopathology | Cognitive Dysfunction - epidemiology | Aged, 80 and over | Cognition - physiology | Cognitive Dysfunction - psychology | Depression - complications | Female | Cognitive Dysfunction - complications | Neoplasms - physiopathology | Patient Reported Outcome Measures | Depression - epidemiology | Cross-Sectional Studies | Hearing Loss - physiopathology | Hearing Loss - epidemiology | Self Report | Vision Disorders - psychology | Hearing Loss - complications | Neoplasms - psychology | Cognitive Dysfunction - physiopathology | Aged | Vision Disorders - epidemiology | Neoplasms - epidemiology | Elderly people | Lung | Cognitive ability | Impairment | Cognition | Mental depression | Older people | Dependence | Anxiety | Secondary analysis | Visually handicapped people | Activities of daily living | Regression analysis | Hearing impairment | Patients | Variance analysis | Hearing loss | Chemotherapy | Hearing | Anxieties | Visual impairment | Blindness | Adults | Solid tumors | Cancer | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Ophthalmology, ISSN 0002-9394, 2015, Volume 159, Issue 4, pp. 690 - 697
Journal Article
Audiology and Neurotology, ISSN 1420-3030, 06/2012, Volume 17, Issue 4, pp. 219 - 227
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0170804 - e0170804
Objective To determine the prevalence, risk factors, and impact of undiagnosed visually significant cataract in an Asian population. Methods The Singapore... 
SURGERY | SURVIVAL | POPULATION | METHODOLOGY | ANDHRA-PRADESH | MULTIDISCIPLINARY SCIENCES | LENS OPACITIES | ADULTS | PEOPLE | RURAL CHINESE | IMPAIRMENT | Diabetes Complications - physiopathology | Cataract - diagnosis | Humans | Middle Aged | Risk Factors | Male | Cataract - epidemiology | Diabetes Complications - diagnosis | Eye Diseases - diagnosis | Vision Disorders - diagnosis | Vision Disorders - physiopathology | Vision, Ocular - physiology | Ethnic Groups | Aged, 80 and over | Diabetes Complications - epidemiology | Eye Diseases - epidemiology | Quality of Life | Adult | Female | Aged | Vision Disorders - epidemiology | Cataract - physiopathology | Eye Diseases - physiopathology | Eye - physiopathology | Complications and side effects | Vision disorders | Cataract | Health promotion | Blindness | Diagnosis | Planning | Risk factors | Elderly people | Cataracts | Diabetic retinopathy | Impairment | Population studies | Epidemiology | Medical schools | Visual perception | Acuity | Eye | Archives & records | Older people | Population | Public health | Visually handicapped people | Evaluation | Medical research | Task forces | Mortality | Diabetes mellitus | Visual acuity | Eye surgery | Risk analysis | Minority & ethnic groups | Quality of life | Studies | Ethnicity | Visual impairment | Eye diseases | Adults | Asian Americans | Diabetes | Elderly | Geriatrics | Eye lens | Index Medicus
Journal Article